The Experts below are selected from a list of 195 Experts worldwide ranked by ideXlab platform
Sek-kwong Poon - One of the best experts on this subject based on the ideXlab platform.
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Increased accuracy of the carbon-14d-xylose breath test in detecting small-intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14 d -xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of^14C- d -xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of^14C- d -xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of^14C- d -xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of^14C- d -xylose that entered the small intestine. The results of the percentage of expired^14CO_2 at 30 min were corrected with the amount of^14C- d -xylose that entered the small intestine. There were six patients in the culture-positive group with a^14CO_2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of^14C- d -xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected^14C- d -xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected^14C- d -xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of^14C- d -xylose as a Correcting Factor, we found a higher sensitivity and specificity for the^14C- d -xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
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increased accuracy of the carbon 14 d xylose breath test in detecting small intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine and Molecular Imaging, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14d-xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of14C-d-xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of14C-d-xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of14C-d-xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of14C-d-xylose that entered the small intestine. The results of the percentage of expired14CO2 at 30 min were corrected with the amount of14C-d-xylose that entered the small intestine. There were six patients in the culture-positive group with a14CO2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of14C-d-xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected14C-d-xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected14C-d-xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of14C-d-xylose as a Correcting Factor, we found a higher sensitivity and specificity for the14C-d-xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
Chi-sen Chang - One of the best experts on this subject based on the ideXlab platform.
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Increased accuracy of the carbon-14d-xylose breath test in detecting small-intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14 d -xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of^14C- d -xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of^14C- d -xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of^14C- d -xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of^14C- d -xylose that entered the small intestine. The results of the percentage of expired^14CO_2 at 30 min were corrected with the amount of^14C- d -xylose that entered the small intestine. There were six patients in the culture-positive group with a^14CO_2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of^14C- d -xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected^14C- d -xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected^14C- d -xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of^14C- d -xylose as a Correcting Factor, we found a higher sensitivity and specificity for the^14C- d -xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
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increased accuracy of the carbon 14 d xylose breath test in detecting small intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine and Molecular Imaging, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14d-xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of14C-d-xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of14C-d-xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of14C-d-xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of14C-d-xylose that entered the small intestine. The results of the percentage of expired14CO2 at 30 min were corrected with the amount of14C-d-xylose that entered the small intestine. There were six patients in the culture-positive group with a14CO2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of14C-d-xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected14C-d-xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected14C-d-xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of14C-d-xylose as a Correcting Factor, we found a higher sensitivity and specificity for the14C-d-xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
Shih-nen Peng - One of the best experts on this subject based on the ideXlab platform.
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Increased accuracy of the carbon-14d-xylose breath test in detecting small-intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14 d -xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of^14C- d -xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of^14C- d -xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of^14C- d -xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of^14C- d -xylose that entered the small intestine. The results of the percentage of expired^14CO_2 at 30 min were corrected with the amount of^14C- d -xylose that entered the small intestine. There were six patients in the culture-positive group with a^14CO_2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of^14C- d -xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected^14C- d -xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected^14C- d -xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of^14C- d -xylose as a Correcting Factor, we found a higher sensitivity and specificity for the^14C- d -xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
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increased accuracy of the carbon 14 d xylose breath test in detecting small intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine and Molecular Imaging, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14d-xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of14C-d-xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of14C-d-xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of14C-d-xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of14C-d-xylose that entered the small intestine. The results of the percentage of expired14CO2 at 30 min were corrected with the amount of14C-d-xylose that entered the small intestine. There were six patients in the culture-positive group with a14CO2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of14C-d-xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected14C-d-xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected14C-d-xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of14C-d-xylose as a Correcting Factor, we found a higher sensitivity and specificity for the14C-d-xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
Chih-kuen Huang - One of the best experts on this subject based on the ideXlab platform.
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Increased accuracy of the carbon-14d-xylose breath test in detecting small-intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14 d -xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of^14C- d -xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of^14C- d -xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of^14C- d -xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of^14C- d -xylose that entered the small intestine. The results of the percentage of expired^14CO_2 at 30 min were corrected with the amount of^14C- d -xylose that entered the small intestine. There were six patients in the culture-positive group with a^14CO_2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of^14C- d -xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected^14C- d -xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected^14C- d -xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of^14C- d -xylose as a Correcting Factor, we found a higher sensitivity and specificity for the^14C- d -xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
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increased accuracy of the carbon 14 d xylose breath test in detecting small intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine and Molecular Imaging, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14d-xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of14C-d-xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of14C-d-xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of14C-d-xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of14C-d-xylose that entered the small intestine. The results of the percentage of expired14CO2 at 30 min were corrected with the amount of14C-d-xylose that entered the small intestine. There were six patients in the culture-positive group with a14CO2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of14C-d-xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected14C-d-xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected14C-d-xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of14C-d-xylose as a Correcting Factor, we found a higher sensitivity and specificity for the14C-d-xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
Gran-hum Chen - One of the best experts on this subject based on the ideXlab platform.
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Increased accuracy of the carbon-14d-xylose breath test in detecting small-intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14 d -xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of^14C- d -xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of^14C- d -xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of^14C- d -xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of^14C- d -xylose that entered the small intestine. The results of the percentage of expired^14CO_2 at 30 min were corrected with the amount of^14C- d -xylose that entered the small intestine. There were six patients in the culture-positive group with a^14CO_2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of^14C- d -xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected^14C- d -xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected^14C- d -xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of^14C- d -xylose as a Correcting Factor, we found a higher sensitivity and specificity for the^14C- d -xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
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increased accuracy of the carbon 14 d xylose breath test in detecting small intestinal bacterial overgrowth by correction with the gastric emptying rate
European Journal of Nuclear Medicine and Molecular Imaging, 1995Co-Authors: Chi-sen Chang, Gran-hum Chen, Shih-nen Peng, Chih-kuen Huang, Chia-hung Kao, Shyh-jen Wang, Sek-kwong PoonAbstract:To date, there is no general agreement as to which test is to be preferred for the diagnosis of small-intestinal bacterial overgrowth. The 1-g carbon-14d-xylose breath test has been proposed as a very sensitive and specific test for the diagnosis of bacterial overgrowth. However, in patients with severe gastrointestinal motor dysfunction, the lack of consistent delivery of14C-d-xylose to the region of bacterial contamination may result in a “negative” result. The aim of this study was to determine whether the accuracy of14C-d-xylose breath test for detecting bacterial overgrowth can be increased by correction with the gastric emptying rate of14C-d-xylose. Ten culture-positive patients and ten culture-negative controls were included in the study. Small-intestinal aspirates for bacteriological culture were obtained endoscopically. A liquid-phase gastric emptying study was performed simultaneously to assess the amount of14C-d-xylose that entered the small intestine. The results of the percentage of expired14CO2 at 30 min were corrected with the amount of14C-d-xylose that entered the small intestine. There were six patients in the culture-positive group with a14CO2 concentration above the normal limit. Three out of four patients with initially negative results using the uncorrected method proved to be positive after correction. All these three patients had prolonged gastric emptying of14C-d-xylose. When compared with cultures of small-intestine aspirates, the sensitivity and specificity of the uncorrected14C-d-xylose breath test were 60% and 90%, respectively. In contrast, the sensitivity and specificity of the corrected14C-d-xylose breath test improved to 90% and 100%, respectively. In conclusion, using the gastric emptying rate of14C-d-xylose as a Correcting Factor, we found a higher sensitivity and specificity for the14C-d-xylose breath test in the detection of small-intestinal bacterial overgrowth than were achieved with the conventional method.
