Coumarin Derivative

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Hui Zhang - One of the best experts on this subject based on the ideXlab platform.

  • antiviral efficiency of a Coumarin Derivative on spring viremia of carp virus in vivo
    Virus Research, 2019
    Co-Authors: Guanglu Liu, Hui Zhang, Chunjie Wang, Haifeng Wang, Lili Zhu, Yunsheng Wang, Chaoyu Pei, Lei Liu
    Abstract:

    Abstract Spring viraemia of carp (SVC) in aquaculture is challenging because there are few preventative measures and/or treatments. The previous study demonstrated that an antiviral Coumarin Derivative, 7-(4-(4-methyl-imidazole))-Coumarin (C2), inhibits spring viremia of carp virus (SVCV) infection by targeting Nrf2-ARE signaling pathway in fish cells. Thus, we hypothesized whether C2 may be used as a potential therapeutic agent for controlling SVCV infection in aquaculture. In this study, SVCV infectivity was significantly inhibited in vitro in a dose-dependent manner by preincubation with C2. C2 was verified against SVCV in zebrafish, in which the mortality and viral titer in fish body were decreased. Like other Coumarins, C2 was stable with a prolonged inhibitory half-life (3.5 days) at 15 °C in the early stage of SVCV infection. The results show that horizontal transmission of SVCV was reduced by C2 in a static cohabitation challenge model, especially for recipient fish in injection treatment, which suggested that C2 may be suitable as a possible therapeutic agent for SVCV in aquaculture. Overall, this study provides the new insight that a small molecule antiviral drug can be used to control rhabdovirus infection in fish aquacultures.

  • high efficiency blue electroluminescence based on Coumarin Derivative 3 4 anthracen 10 yl phenyl benzo 5 6 Coumarin
    Journal of Fluorescence, 2012
    Co-Authors: Hui Zhang, Tianzhi Yu, Haifang Chai, Yuling Zhao
    Abstract:

    The electroluminescent (EL) properties of a new Coumarin Derivative, 3-(4-(anthracen-10-yl)phenyl)-benzo[5,6]Coumarin (APBC), were investigated. The results show that the EL devices comprised of vacuum vapor-deposited films using the Derivative as dopant exhibited blue emission that is identical to the photoluminescence of the thin film. The electroluminescence device of ITO/2-TNATA (5 nm)/NPB (40 nm)/CBP : APBC (1.0 wt%, 30 nm)/PBD (30 nm)/LiF (1 nm)/Al (100 nm) gives a maximum luminous efficiency of 2.3 cd/A at the current density of 20 mA/cm2, and maximum luminance of 5169 cd/m2 at 16 V. The external quantum efficiency of the device is 1.85 %.

  • synthesis crystal structure and photoluminescent property of an iridium complex with Coumarin Derivative ligand
    Inorganica Chimica Acta, 2011
    Co-Authors: Sidan Yang, Hui Zhang, Yuling Zhao, Duowang Fan, Xiaoqian Han, Zaiman Liu
    Abstract:

    Novel iridium complex containing Coumarin Derivative as a cyclometalated ligand (L) and picolinate (pic) as the ancillary ligand, Ir(III) bis (3-(pyridin-2-yl)Coumarinato N,C 4 )(picolinate) [Ir(L) 2 (pic)], was synthesized and characterized. It was demonstrated that the iridium (III) ion in Ir(L) 2 (pic) is hexacoordinated by two C atoms and two N atoms from 3-(pyridin-2-yl)Coumarin ligands and one N atom and one O atom from picolinate ligand, displaying a distorted octahedral coordination geometry. The Ir(L) 2 (pic) has very strong absorption and intensive emission at 532 nm. These results show the promising future of that Ir(L) 2 (pic) in fabrication organic light-emitting diodes.

  • synthesis crystal structure and photoluminescence of 3 4 anthracen 10 yl phenyl benzo 5 6 Coumarin
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2010
    Co-Authors: Hui Zhang, Tianzhi Yu, Yuling Zhao, Peng Zhang, Lili Chen
    Abstract:

    Abstract A new Coumarin Derivative, 3-(4-(anthracen-10-yl)phenyl)-benzo[5,6]Coumarin, was synthesized and characterized by FT-IR, 1H NMR, element analysis and single crystal X-ray crystallography. The dihedral angle of benzo[5,6]Coumarin ring and phenyl group is 36.15°, and the dihedral angle of phenyl group and anthracene skeleton is 89.37°. The UV–vis absorption and photoluminescence of the compound were discussed. The result shown that the compound exhibits high fluorescence quantum yield (ΦF), large Stokes shift and green emission (508 nm). The molecular structure of the compound was optimized using density functional theory (DFT) at B3LYP/6-31G(d) level, and the HOMO and LUMO levels of the compound were deduced.

Yuling Zhao - One of the best experts on this subject based on the ideXlab platform.

  • high efficiency blue electroluminescence based on Coumarin Derivative 3 4 anthracen 10 yl phenyl benzo 5 6 Coumarin
    Journal of Fluorescence, 2012
    Co-Authors: Hui Zhang, Tianzhi Yu, Haifang Chai, Yuling Zhao
    Abstract:

    The electroluminescent (EL) properties of a new Coumarin Derivative, 3-(4-(anthracen-10-yl)phenyl)-benzo[5,6]Coumarin (APBC), were investigated. The results show that the EL devices comprised of vacuum vapor-deposited films using the Derivative as dopant exhibited blue emission that is identical to the photoluminescence of the thin film. The electroluminescence device of ITO/2-TNATA (5 nm)/NPB (40 nm)/CBP : APBC (1.0 wt%, 30 nm)/PBD (30 nm)/LiF (1 nm)/Al (100 nm) gives a maximum luminous efficiency of 2.3 cd/A at the current density of 20 mA/cm2, and maximum luminance of 5169 cd/m2 at 16 V. The external quantum efficiency of the device is 1.85 %.

  • synthesis crystal structure and photoluminescent property of an iridium complex with Coumarin Derivative ligand
    Inorganica Chimica Acta, 2011
    Co-Authors: Sidan Yang, Hui Zhang, Yuling Zhao, Duowang Fan, Xiaoqian Han, Zaiman Liu
    Abstract:

    Novel iridium complex containing Coumarin Derivative as a cyclometalated ligand (L) and picolinate (pic) as the ancillary ligand, Ir(III) bis (3-(pyridin-2-yl)Coumarinato N,C 4 )(picolinate) [Ir(L) 2 (pic)], was synthesized and characterized. It was demonstrated that the iridium (III) ion in Ir(L) 2 (pic) is hexacoordinated by two C atoms and two N atoms from 3-(pyridin-2-yl)Coumarin ligands and one N atom and one O atom from picolinate ligand, displaying a distorted octahedral coordination geometry. The Ir(L) 2 (pic) has very strong absorption and intensive emission at 532 nm. These results show the promising future of that Ir(L) 2 (pic) in fabrication organic light-emitting diodes.

  • synthesis crystal structure and photoluminescence of 3 4 anthracen 10 yl phenyl benzo 5 6 Coumarin
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2010
    Co-Authors: Hui Zhang, Tianzhi Yu, Yuling Zhao, Peng Zhang, Lili Chen
    Abstract:

    Abstract A new Coumarin Derivative, 3-(4-(anthracen-10-yl)phenyl)-benzo[5,6]Coumarin, was synthesized and characterized by FT-IR, 1H NMR, element analysis and single crystal X-ray crystallography. The dihedral angle of benzo[5,6]Coumarin ring and phenyl group is 36.15°, and the dihedral angle of phenyl group and anthracene skeleton is 89.37°. The UV–vis absorption and photoluminescence of the compound were discussed. The result shown that the compound exhibits high fluorescence quantum yield (ΦF), large Stokes shift and green emission (508 nm). The molecular structure of the compound was optimized using density functional theory (DFT) at B3LYP/6-31G(d) level, and the HOMO and LUMO levels of the compound were deduced.

Lili Chen - One of the best experts on this subject based on the ideXlab platform.

  • synthesis crystal structure and photoluminescence of 3 4 anthracen 10 yl phenyl benzo 5 6 Coumarin
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2010
    Co-Authors: Hui Zhang, Tianzhi Yu, Yuling Zhao, Peng Zhang, Lili Chen
    Abstract:

    Abstract A new Coumarin Derivative, 3-(4-(anthracen-10-yl)phenyl)-benzo[5,6]Coumarin, was synthesized and characterized by FT-IR, 1H NMR, element analysis and single crystal X-ray crystallography. The dihedral angle of benzo[5,6]Coumarin ring and phenyl group is 36.15°, and the dihedral angle of phenyl group and anthracene skeleton is 89.37°. The UV–vis absorption and photoluminescence of the compound were discussed. The result shown that the compound exhibits high fluorescence quantum yield (ΦF), large Stokes shift and green emission (508 nm). The molecular structure of the compound was optimized using density functional theory (DFT) at B3LYP/6-31G(d) level, and the HOMO and LUMO levels of the compound were deduced.

Tianzhi Yu - One of the best experts on this subject based on the ideXlab platform.

  • high efficiency blue electroluminescence based on Coumarin Derivative 3 4 anthracen 10 yl phenyl benzo 5 6 Coumarin
    Journal of Fluorescence, 2012
    Co-Authors: Hui Zhang, Tianzhi Yu, Haifang Chai, Yuling Zhao
    Abstract:

    The electroluminescent (EL) properties of a new Coumarin Derivative, 3-(4-(anthracen-10-yl)phenyl)-benzo[5,6]Coumarin (APBC), were investigated. The results show that the EL devices comprised of vacuum vapor-deposited films using the Derivative as dopant exhibited blue emission that is identical to the photoluminescence of the thin film. The electroluminescence device of ITO/2-TNATA (5 nm)/NPB (40 nm)/CBP : APBC (1.0 wt%, 30 nm)/PBD (30 nm)/LiF (1 nm)/Al (100 nm) gives a maximum luminous efficiency of 2.3 cd/A at the current density of 20 mA/cm2, and maximum luminance of 5169 cd/m2 at 16 V. The external quantum efficiency of the device is 1.85 %.

  • synthesis crystal structure and photoluminescence of 3 4 anthracen 10 yl phenyl benzo 5 6 Coumarin
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2010
    Co-Authors: Hui Zhang, Tianzhi Yu, Yuling Zhao, Peng Zhang, Lili Chen
    Abstract:

    Abstract A new Coumarin Derivative, 3-(4-(anthracen-10-yl)phenyl)-benzo[5,6]Coumarin, was synthesized and characterized by FT-IR, 1H NMR, element analysis and single crystal X-ray crystallography. The dihedral angle of benzo[5,6]Coumarin ring and phenyl group is 36.15°, and the dihedral angle of phenyl group and anthracene skeleton is 89.37°. The UV–vis absorption and photoluminescence of the compound were discussed. The result shown that the compound exhibits high fluorescence quantum yield (ΦF), large Stokes shift and green emission (508 nm). The molecular structure of the compound was optimized using density functional theory (DFT) at B3LYP/6-31G(d) level, and the HOMO and LUMO levels of the compound were deduced.

Peng Zhang - One of the best experts on this subject based on the ideXlab platform.

  • synthesis crystal structure and photoluminescence of 3 4 anthracen 10 yl phenyl benzo 5 6 Coumarin
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2010
    Co-Authors: Hui Zhang, Tianzhi Yu, Yuling Zhao, Peng Zhang, Lili Chen
    Abstract:

    Abstract A new Coumarin Derivative, 3-(4-(anthracen-10-yl)phenyl)-benzo[5,6]Coumarin, was synthesized and characterized by FT-IR, 1H NMR, element analysis and single crystal X-ray crystallography. The dihedral angle of benzo[5,6]Coumarin ring and phenyl group is 36.15°, and the dihedral angle of phenyl group and anthracene skeleton is 89.37°. The UV–vis absorption and photoluminescence of the compound were discussed. The result shown that the compound exhibits high fluorescence quantum yield (ΦF), large Stokes shift and green emission (508 nm). The molecular structure of the compound was optimized using density functional theory (DFT) at B3LYP/6-31G(d) level, and the HOMO and LUMO levels of the compound were deduced.