The Experts below are selected from a list of 258 Experts worldwide ranked by ideXlab platform
S Sasayama - One of the best experts on this subject based on the ideXlab platform.
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Enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina; evaluation by(13)N-ammonia positron emission tomography.
European heart journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P
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enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina evaluation by 13 n ammonia positron emission tomography
European Heart Journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P <0·05). In ischaemic regions, particularly the anterior region, myocardial perfusion at rest and with dipyridamole and coronary flow reserve improved significantly after therapy (at rest: 0·71±0·26 to 0·86±0·31; P <0·05, with dipyridamole: 1·26±0·65 to 1·84±0·94; P <0·02, coronary flow reserve: 1·75±0·24 to 2·08±0·28; P <0·04). Exercise time was prolonged and the time to 1-mm ST depression improved markedly ( P <0·01). After therapy, nitric oxide levels increased ( P <0·02) and neurohumoral factors decreased. Conclusions Enhanced external Counterpulsation therapy improved myocardial perfusion at rest and with dipyridamole and was associated with an increased exercise tolerance with13N-ammonia positron emission tomography and increased nitric oxide levels. These results suggest that one of the enhanced external Counterpulsation mechanisms is development and recruitment of collateral vessels.
Daisuke Masuda - One of the best experts on this subject based on the ideXlab platform.
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Enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina; evaluation by(13)N-ammonia positron emission tomography.
European heart journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P
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enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina evaluation by 13 n ammonia positron emission tomography
European Heart Journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P <0·05). In ischaemic regions, particularly the anterior region, myocardial perfusion at rest and with dipyridamole and coronary flow reserve improved significantly after therapy (at rest: 0·71±0·26 to 0·86±0·31; P <0·05, with dipyridamole: 1·26±0·65 to 1·84±0·94; P <0·02, coronary flow reserve: 1·75±0·24 to 2·08±0·28; P <0·04). Exercise time was prolonged and the time to 1-mm ST depression improved markedly ( P <0·01). After therapy, nitric oxide levels increased ( P <0·02) and neurohumoral factors decreased. Conclusions Enhanced external Counterpulsation therapy improved myocardial perfusion at rest and with dipyridamole and was associated with an increased exercise tolerance with13N-ammonia positron emission tomography and increased nitric oxide levels. These results suggest that one of the enhanced external Counterpulsation mechanisms is development and recruitment of collateral vessels.
Li-guang Chen - One of the best experts on this subject based on the ideXlab platform.
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Enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina; evaluation by(13)N-ammonia positron emission tomography.
European heart journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P
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enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina evaluation by 13 n ammonia positron emission tomography
European Heart Journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P <0·05). In ischaemic regions, particularly the anterior region, myocardial perfusion at rest and with dipyridamole and coronary flow reserve improved significantly after therapy (at rest: 0·71±0·26 to 0·86±0·31; P <0·05, with dipyridamole: 1·26±0·65 to 1·84±0·94; P <0·02, coronary flow reserve: 1·75±0·24 to 2·08±0·28; P <0·04). Exercise time was prolonged and the time to 1-mm ST depression improved markedly ( P <0·01). After therapy, nitric oxide levels increased ( P <0·02) and neurohumoral factors decreased. Conclusions Enhanced external Counterpulsation therapy improved myocardial perfusion at rest and with dipyridamole and was associated with an increased exercise tolerance with13N-ammonia positron emission tomography and increased nitric oxide levels. These results suggest that one of the enhanced external Counterpulsation mechanisms is development and recruitment of collateral vessels.
Ryuji Nohara - One of the best experts on this subject based on the ideXlab platform.
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Enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina; evaluation by(13)N-ammonia positron emission tomography.
European heart journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P
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enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina evaluation by 13 n ammonia positron emission tomography
European Heart Journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P <0·05). In ischaemic regions, particularly the anterior region, myocardial perfusion at rest and with dipyridamole and coronary flow reserve improved significantly after therapy (at rest: 0·71±0·26 to 0·86±0·31; P <0·05, with dipyridamole: 1·26±0·65 to 1·84±0·94; P <0·02, coronary flow reserve: 1·75±0·24 to 2·08±0·28; P <0·04). Exercise time was prolonged and the time to 1-mm ST depression improved markedly ( P <0·01). After therapy, nitric oxide levels increased ( P <0·02) and neurohumoral factors decreased. Conclusions Enhanced external Counterpulsation therapy improved myocardial perfusion at rest and with dipyridamole and was associated with an increased exercise tolerance with13N-ammonia positron emission tomography and increased nitric oxide levels. These results suggest that one of the enhanced external Counterpulsation mechanisms is development and recruitment of collateral vessels.
Tadakazu Hirai - One of the best experts on this subject based on the ideXlab platform.
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Enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina; evaluation by(13)N-ammonia positron emission tomography.
European heart journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P
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enhanced external Counterpulsation improved myocardial perfusion and coronary flow reserve in patients with chronic stable angina evaluation by 13 n ammonia positron emission tomography
European Heart Journal, 2001Co-Authors: Daisuke Masuda, Ryuji Nohara, Tadakazu Hirai, Kazuaki Kataoka, Li-guang Chen, Ryohei Hosokawa, M Inubushi, Eiji Tadamura, Masatoshi Fujita, S SasayamaAbstract:Aims The mechanism by which enhanced external Counterpulsation therapy exerts its beneficial effects on chronic and symptomatic stable angina is largely unknown. To clarify the mechanism of action of enhanced external Counterpulsation, we used13N-ammonia positron emission tomography to evaluate myocardial perfusion. Methods and Results This was not a randomized controlled study. Eleven patients (eight male, age: 61·6±9·7) with angina pectoris underwent enhanced external Counterpulsation therapy for 35 1h sessions. They underwent a treadmill exercise test and13N-ammonia positron emission tomography, both at rest and with dipyridamole, before and after enhanced external Counterpulsation therapy. Neurohumoral factors and nitric oxide were also evaluated. Myocardial perfusion increased at rest after therapy (0·69±0·27 to 0·85±0·47ml.min−1.g−1, P <0·05). In ischaemic regions, particularly the anterior region, myocardial perfusion at rest and with dipyridamole and coronary flow reserve improved significantly after therapy (at rest: 0·71±0·26 to 0·86±0·31; P <0·05, with dipyridamole: 1·26±0·65 to 1·84±0·94; P <0·02, coronary flow reserve: 1·75±0·24 to 2·08±0·28; P <0·04). Exercise time was prolonged and the time to 1-mm ST depression improved markedly ( P <0·01). After therapy, nitric oxide levels increased ( P <0·02) and neurohumoral factors decreased. Conclusions Enhanced external Counterpulsation therapy improved myocardial perfusion at rest and with dipyridamole and was associated with an increased exercise tolerance with13N-ammonia positron emission tomography and increased nitric oxide levels. These results suggest that one of the enhanced external Counterpulsation mechanisms is development and recruitment of collateral vessels.
