The Experts below are selected from a list of 35280 Experts worldwide ranked by ideXlab platform
Mikio Namiki - One of the best experts on this subject based on the ideXlab platform.
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Cumulative Probability of prostate cancer detection in biopsy according to free total psa ratio in men with total psa levels of 2 1 10 0 ng ml at population screening
Journal of Cancer Research and Clinical Oncology, 2014Co-Authors: Yasuhide Kitagawa, Satoru Ueno, Kouji Izumi, Yoshifumi Kadono, Hiroyuki Konaka, Atsushi Mizokami, Mikio NamikiAbstract:Purpose The aim of this study was to investigate the Cumulative Probability of prostate cancer detection according to free/total prostate-specific antigen (PSA) ratio in men with PSA levels of 2.1–10.0 ng/ml and also likelihood of detecting clinically insignificant prostate cancer in population-based screening.
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Cumulative Probability of prostate cancer detection using the international prostate symptom score in a prostate specific antigen based population screening program in japan
Asian Pacific Journal of Cancer Prevention, 2014Co-Authors: Yasuhide Kitagawa, Kouji Izumi, Yoshifumi Kadono, Hiroyuki Konaka, Atsushi Mizokami, Satoko Urata, Kazutaka Narimoto, Tomomi Nakagawa, Mikio NamikiAbstract:The International Prostate Symptom Score (IPSS) is often used as an interview sheet for assessing lower urinary tract symptoms (LUTS) at the time of prostate-specific antigen (PSA) testing during population-based screening for prostate cancer. However, the relationship between prostate cancer detection and LUTS status remains controversial. To elucidate this relationship, the Cumulative Probability of prostate cancer detection using IPSS in biopsy samples from patients categorized by serum PSA levels was investigated. The clinical characteristics of prostate cancer detected using IPSS during screening were also investigated. A total of 1,739 men aged 54-75 years with elevated serum PSA levels who completed the IPSS questionnaire during the initial population screening in Kanazawa City, Japan and underwent systematic transrectal ultrasonography-guided prostate biopsy between 2000 and 2013 were enrolled in the present study. Of the 1,739 men, 544 (31.3%) were diagnosed with prostate cancer during the observation period. The Probability of cancer detection at 3 years in the entire study population was 27.4% and 32.7% for men with IPSS≤7 and those with IPSS≥8, respectively; there was no statistically significant difference between groups. In men with serum PSA levels of 6.1 to 12.0ng/ mL at initial screening, the Probability of cancer detection was significantly higher in men with IPSS≤7 than in those with IPSS≥8. There were no significant differences in clinical characteristics between groups of patients stratified by IPSS. These findings indicate that the use of IPSS for LUTS status evaluation may be useful for prostate cancer detection in the limited range of serum PSA levels.
Didi D.m. Braat - One of the best experts on this subject based on the ideXlab platform.
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Cumulative Probability of achieving an ongoing pregnancy after in-vitro fertilization and intracytoplasmic sperm injection according to a woman's age, subfertility diagnosis and primary or secondary subfertility
Human Reproduction, 2000Co-Authors: Annette M. Stolwijk, Alex M.m. Wetzels, Didi D.m. BraatAbstract:The aim of this study was to estimate reliable Cumulative probabilities of achieving an ongoing pregnancy after successive in-vitro fertilization or intracytoplasmic sperm injection (IVF/ICSI) cycles, according to a woman's age, subfertility diagnosis and primary or secondary subfertility. Therefore reasons for quitting treatment without achieving an ongoing pregnancy were taken into account. Moreover, we studied whether there were trends in Cumulative probabilities after adjustment for potential confounding effects of the other two characteristics, duration of subfertility, year of first treatment and reason for quitting treatment. In total, 2984 IVF/ICSI cycles were performed in 1315 couples at the University Hospital Nijmegen, The Netherlands, between 1991 and 1998. The 'realistic' Cumulative Probability of achieving an ongoing pregnancy was 54.5% after five consecutive IVF/ICSI cycles, which was about 10% lower (absolute value) than the optimistic Probability calculated by life-table analysis and about 10% higher (absolute value) than the most pessimistic estimate. Women of 35 years or younger had a higher Probability of achieving an ongoing pregnancy than the older women. As ICSI is now an option, there were no obvious differences between the subfertility diagnosis subgroups. The Cumulative Probability after the first two IVF/ICSI cycles was higher in women with secondary subfertility than in those with primary subfertility; this advantage disappeared after further treatment. These trends remained valid after adjustment for confounding factors.
Kelly Benfer - One of the best experts on this subject based on the ideXlab platform.
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comparison of the Cumulative Probability of pregnancy after in vitro fertilization embryo transfer by infertility factor and age
Fertility and Sterility, 1994Co-Authors: J H Check, D Lurie, Carrie Callan, Amy Baker, Kelly BenferAbstract:Objective To compare the Cumulative Probability of pregnancy after multiple IVF cycles by age and cause of infertility. Design A prospective study was done in which patients were followed from the time they registered for their first IVF cycle until they achieved a clinical pregnancy, withdrew from treatment, or study was terminated. Patients, Setting, Treatments Infertile women undergoing IVF-ET at the Cooper Institute for In Vitro Fertilization were enrolled in this study if the luteal phase leuprolide acetate (LA) and hMG controlled ovarian hyperstimulation (COH) regimen was used. Main Outcome Measures Clinical pregnancy, as determined by a positive β -hCG level and ultrasonographic confirmation of a gestational sac, and delivery rates based on number of women with live births were compared by infertility factor and age. Results The 3-month Cumulative Probability of pregnancy based on life table analysis was 33% in women with tubal factor who were ≤35years of age, 25% in women with tubal factor who were >35years of age, 30% for women with multiple factors who were ≤35years of age, and 14% for women with multiple factors who were >35years of age. The rate for the older women with multiple factors was significantly lower than that for the other groups. The delivery rates were lower for the women with multiple factors than for women under 35 with tubal factor only. Conclusions There is a significant effect of age and infertility factor on pregnancy and delivery rates. Physicians should consider these factors in evaluating their patients' prospects for success in IVF-ET.
B A Malizia - One of the best experts on this subject based on the ideXlab platform.
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the Cumulative Probability of liveborn multiples after in vitro fertilization a cohort study of more than 10 000 women
Fertility and Sterility, 2013Co-Authors: B A Malizia, Laura E Dodge, Alan S Penzias, Michele R HackerAbstract:Objective To estimate the Cumulative Probability of liveborn multiples after IVF to improve patient counseling regarding this significant morbidity. Design Retrospective cohort study. Setting Large academic-affiliated infertility practice. Patient(s) A total of 10,169 women were followed from their first fresh, nondonor IVF cycle through up to six fresh and frozen IVF cycles from 2000–2010. Intervention(s) None. Main Outcome Measure(s) Delivery of a liveborn infant(s). Result(s) After three IVF cycles the Cumulative live birth rate (CLBR) was 53.2%. The singleton, twin, and triplet CLBRs were 38.0%, 14.5%, and 0.7%. After six IVF cycles the CLBR was 73.8%, with 52.8%, 19.8%, 1.3% for singletons, twins, and triplets. Of the 5,433 live births, 71.4% were singletons, 27.1% were twins, and 1.5% were triplets. Women more than 39 years had the lowest incidence of liveborn multiples with CLBRs of 5.2% after three cycles and 9.5% after six cycles. The twin CLBR doubled from cycles 1 through 3 with the rate of increase slowing from cycles 3 through 6. Although very low in absolute terms, the triplet CLBR also doubled from cycles 1 through 3 and doubled again from cycles 3 through 6. Of the 1,970 pregnancies that began as multifetal on ultrasound, 77.4% resulted in liveborn multiples. Conclusion(s) Providers should be aware of the Cumulative Probability of liveborn multiples to effectively counsel patients on this important issue. With nearly three-quarters of all women having live birth after up to six IVF cycles, it is encouraging to report a low incidence of liveborn multiples.
Yasuhide Kitagawa - One of the best experts on this subject based on the ideXlab platform.
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Cumulative Probability of prostate cancer detection in biopsy according to free total psa ratio in men with total psa levels of 2 1 10 0 ng ml at population screening
Journal of Cancer Research and Clinical Oncology, 2014Co-Authors: Yasuhide Kitagawa, Satoru Ueno, Kouji Izumi, Yoshifumi Kadono, Hiroyuki Konaka, Atsushi Mizokami, Mikio NamikiAbstract:Purpose The aim of this study was to investigate the Cumulative Probability of prostate cancer detection according to free/total prostate-specific antigen (PSA) ratio in men with PSA levels of 2.1–10.0 ng/ml and also likelihood of detecting clinically insignificant prostate cancer in population-based screening.
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Cumulative Probability of prostate cancer detection using the international prostate symptom score in a prostate specific antigen based population screening program in japan
Asian Pacific Journal of Cancer Prevention, 2014Co-Authors: Yasuhide Kitagawa, Kouji Izumi, Yoshifumi Kadono, Hiroyuki Konaka, Atsushi Mizokami, Satoko Urata, Kazutaka Narimoto, Tomomi Nakagawa, Mikio NamikiAbstract:The International Prostate Symptom Score (IPSS) is often used as an interview sheet for assessing lower urinary tract symptoms (LUTS) at the time of prostate-specific antigen (PSA) testing during population-based screening for prostate cancer. However, the relationship between prostate cancer detection and LUTS status remains controversial. To elucidate this relationship, the Cumulative Probability of prostate cancer detection using IPSS in biopsy samples from patients categorized by serum PSA levels was investigated. The clinical characteristics of prostate cancer detected using IPSS during screening were also investigated. A total of 1,739 men aged 54-75 years with elevated serum PSA levels who completed the IPSS questionnaire during the initial population screening in Kanazawa City, Japan and underwent systematic transrectal ultrasonography-guided prostate biopsy between 2000 and 2013 were enrolled in the present study. Of the 1,739 men, 544 (31.3%) were diagnosed with prostate cancer during the observation period. The Probability of cancer detection at 3 years in the entire study population was 27.4% and 32.7% for men with IPSS≤7 and those with IPSS≥8, respectively; there was no statistically significant difference between groups. In men with serum PSA levels of 6.1 to 12.0ng/ mL at initial screening, the Probability of cancer detection was significantly higher in men with IPSS≤7 than in those with IPSS≥8. There were no significant differences in clinical characteristics between groups of patients stratified by IPSS. These findings indicate that the use of IPSS for LUTS status evaluation may be useful for prostate cancer detection in the limited range of serum PSA levels.
