The Experts below are selected from a list of 17226 Experts worldwide ranked by ideXlab platform
Mi Yan-jun - One of the best experts on this subject based on the ideXlab platform.
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Influence of Curcuma Longa on Sports-Fatigue of Mice
Herald of Medicine, 2009Co-Authors: Mi Yan-junAbstract:Objective To study the influence of Curcuma Longa on the exhausted swimming time and biochemical index of blood and organs of mice,probing the anti-sports fatigue effects of which and possible mechanism for its application development in the field of sports. Methods Curcuma Longa were given intragastrically to mice at different dose for 30 days,then continuously loaded-swimming test was carried out. Results It was showed that Curcuma Longa obviously prolonged the loaded-swimming duration of mice,lowered blood urea nitrogen,decreased the consumption of liver glycogen,cut down blood post exercise lactic acid and increased the activity of lactic dehydrogenase. Conclusion Curcuma Longa may have a significant effect on the adaptation to heavy exercise and prevent or eliminate fatigue post exercise.
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Anti-Sports-Fatigue Effects and Mechanism of Curcuma Longa
Herald of Medicine, 2009Co-Authors: Mi Yan-junAbstract:Objective To investigate the anti-sports-fatigue effect of Chinese medicine Curcuma Longa and its mechanism. Methods Continuously pole climbing and anti-anoxia experiments were carried out on mice which were given with Curcuma Longa intragastrically at different doses for 30 days.The skeletal muscle contraction of rats and content of superoxide dismutase(SOD),malonaldehyde(MDA) and Ca2+-Mg2+-ATPase activity were detected. Results It was showed that Curcuma Longa obviously prolonged the time of climbing,raised anti-anoxia capability of mice,enforced the contraction of skeletal muscle and increased activities of Ca2+-Mg2+-ATPase and SOD,lowered the content of MDA. Conclusion Curcuma Longa may have significant effect on the capability of adaptation to heavy exercise and prevention or elimination fatigue after exercise.
Mohamed Salah Allagui - One of the best experts on this subject based on the ideXlab platform.
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Protective effects of Curcuma Longa against neurobehavioral and neurochemical damage caused by cerium chloride in mice
Environmental Science and Pollution Research, 2018Co-Authors: Yamina Kadri, Riadh Nciri, Noura Brahmi, Saber Saidi, Saleh Alwasel, Waleed Aldahmash, Abdelfatteh El Feki, Abdel Halim Harrath, Mohamed Salah AllaguiAbstract:Cerium chloride (CeCl_3) is considered an environmental pollutant and a potent neurotoxic agent. Medicinal plants have many bioactive compounds that provide protection against damage caused by such pollutants. Curcuma Longa is a bioactive compound-rich plant with very important antioxidant properties. To study the preventive and healing effects of Curcuma Longa on cerium-damaged mouse brains, we intraperitoneally injected cerium chloride (CeCl_3, 20 mg/kg BW) along with Curcuma Longa extract, administrated by gavage (100 mg/kg BW), into mice for 60 days. We then examined mouse behavior, brain tissue damage, and brain oxidative stress parameters. Our results revealed a significant modification in the behavior of the CeCl_3-treated mice. In addition, CeCl_3 induced a significant increment in lipid peroxidation, carbonyl protein (PCO), and advanced oxidation protein product levels, as well as a significant reduction in superoxide dismutase (SOD) and glutathione peroxidase (GPx) activities. Acetylcholinesterase (AChE) activity remarkably increased in the brain of CeCl_3-treated mice. Histopathological observations confirmed these results. Curcuma Longa attenuated CeCl_3-induced oxidative stress and increased the activities of antioxidant enzymes. It also decreased AChE activity in the CeCl_3-damaged mouse brain that was confirmed by histopathology. In conclusion, this study suggests that Curcuma Longa has a neuroprotective effect against CeCl_3-induced damage in the brain.
Bhagat Meenakshi - One of the best experts on this subject based on the ideXlab platform.
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contraceptive effect of Curcuma Longa l in male albino rat
Asian Journal of Andrology, 2004Co-Authors: Purohit Ashok, Bhagat MeenakshiAbstract:Aim: To study the contraceptive effect of the crude extracts of Curcuma Longa in male albino rats. Methods: Rats were fed orally with Curcuma Longa aqueous and 70 % alcoholic extract for 60 days (500 mg.kg - 1 day - 1 ). Results: A reduction in sperm motility and density was observed in both the treated groups. Conclusion: Curcuma Longa may have affected the androgen synthesis either by inhibiting the Leydig cell function or the hypothalamus pituitary axis and as a result, spermatogenesis is arrested.
R. Sakthi - One of the best experts on this subject based on the ideXlab platform.
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Wound Healing Activity of Curcuma Longa with Oleum olivae
2015Co-Authors: A. Gayathri, D. Sathish Sekar, R. SakthiAbstract:Wound healing may be defined as a loss or breaking of cellular and anatomic or functional continuity of living tissues. In the present investigation, wound healing activity of Curcuma Longa with Oleum olivae was carried out. The progressive decrease in the wound area was monitored every 3 days tracing the wound margin on a tracing paper and assessed using group paper. The wound contraction was measured as percentage reduction in the wound area in each animal and the damaged skin prior to treatment and regenerated skin after treatment was examined. The wound applied with Curcuma Longa powder with Oleum olivae showed a faster contraction when compared to normal control.
Paulo R. De Melo-reis - One of the best experts on this subject based on the ideXlab platform.
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Physicochemical/photophysical characterization and angiogenic properties of Curcuma Longa essential oil
Anais da Academia Brasileira de Ciências, 2016Co-Authors: Lilhian A. AraÚjo, Rafael G.m. AraÚjo, FlÁvia O. Gomes, Susy R. Lemes, Luciane M. Almeida, Lauro J.q. Maia, Pablo J. GonÇalves, FÁtima MruÉ, Nelson J. Silva-junior, Paulo R. De Melo-reisAbstract:ABSTRACT This study analyzed the physicochemical and photophysical properties of essential oil of Curcuma Longa and its angiogenic potential. The results showed that curcumin is the main fluorescent component present in the oil, although the amount is relatively small. The experimental chorioallantoic membrane model was used to evaluate angiogenic activity, showing a significant increase in the vascular network of Curcuma Longa and positive control groups when compared to the neutral and inhibitor controls (P <0.05), but no significant difference was found between Curcuma Longa essential oil and the positive control (P >0.05). Histological analysis showed extensive neovascularization, hyperemia and inflammation in the positive control group and Curcuma Longa when compared to other controls (P <0.05), characteristic factors of the angiogenesis process. In conclusion, Curcuma Longa oil showed considerable proangiogenic activity and could be a potential compound in medical applications.
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Physicochemical/photophysical characterization and angiogenic properties of Curcuma Longa essential oil.
Anais da Academia Brasileira de Ciencias, 2016Co-Authors: Lilhian A. AraÚjo, Rafael G.m. AraÚjo, FlÁvia O. Gomes, Susy R. Lemes, Luciane M. Almeida, Lauro J.q. Maia, Pablo J. GonÇalves, FÁtima MruÉ, Nelson J. Silva-junior, Paulo R. De Melo-reisAbstract:This study analyzed the physicochemical and photophysical properties of essential oil of Curcuma Longa and its angiogenic potential. The results showed that curcumin is the main fluorescent component present in the oil, although the amount is relatively small. The experimental chorioallantoic membrane model was used to evaluate angiogenic activity, showing a significant increase in the vascular network of Curcuma Longa and positive control groups when compared to the neutral and inhibitor controls (P 0.05). Histological analysis showed extensive neovascularization, hyperemia and inflammation in the positive control group and Curcuma Longa when compared to other controls (P
