The Experts below are selected from a list of 36981 Experts worldwide ranked by ideXlab platform
Yutaka Imai - One of the best experts on this subject based on the ideXlab platform.
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a proposal for the Cutoff Point of waist circumference for the diagnosis of metabolic syndrome in the japanese population
Diabetes Care, 2006Co-Authors: Takayoshi Ohkubo, Masahiro Kikuya, Kei Asayama, Yutaka ImaiAbstract:In a community-based cohort of 692 Japanese individuals, Hara et al. (1) investigated the relationship between Cutoff values used for the waist circumference to define central obesity and rates of detection of subjects displaying multiple risk factors of metabolic syndrome. Using the receiver-operator characteristic (ROC) curve, they proposed an optimal Cutoff Point of waist circumference for the diagnosis of metabolic syndrome …
Luis Paulo Gomes Mascarenhas - One of the best experts on this subject based on the ideXlab platform.
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CARDIORESPIRATORY FITNESS ASSOCIATED TO TEENAGERS' FAT: VO2MAX Cutoff Point.
Revista Paulista De Pediatria, 2019Co-Authors: Leandro Smouter, André De Camargo Smolarek, William Cordeiro De Souza, Valderi Abreu De Lima, Luis Paulo Gomes MascarenhasAbstract:OBJECTIVE: To associate the Maximal Oxygen Uptake (VO2max) with body fat percentage (%BF), and to establish the best VO2max Cutoff Point for predicting risk %BF in teenagers. METHODS: This study was carried out with 979 subjects aged 10 to 18.8 years, 556 (56.8%) girls. The 20 m shuttle run protocol determined the VO2max, which was analyzed in quintiles and in a numeric scale. Cutaneous fold equations determined the %BF, later classified as risk to health/obesity when >25 in girls and >20 in boys. Regression method was used - Odds Ratio (OR) and Receiver Operating Characteristics Curve (ROC curve) with α
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cardiorespiratory fitness associated to teenagers fat vo2max Cutoff Point
Revista Paulista De Pediatria, 2019Co-Authors: Leandro Smouter, André De Camargo Smolarek, William Cordeiro De Souza, Valderi Abreu De Lima, Luis Paulo Gomes MascarenhasAbstract:OBJECTIVE: To associate the Maximal Oxygen Uptake (VO2max) with body fat percentage (%BF), and to establish the best VO2max Cutoff Point for predicting risk %BF in teenagers. METHODS: This study was carried out with 979 subjects aged 10 to 18.8 years, 556 (56.8%) girls. The 20 m shuttle run protocol determined the VO2max, which was analyzed in quintiles and in a numeric scale. Cutaneous fold equations determined the %BF, later classified as risk to health/obesity when >25 in girls and >20 in boys. Regression method was used - Odds Ratio (OR) and Receiver Operating Characteristics Curve (ROC curve) with α <5%. RESULTS: From the total number of valid cases, 341 (65.6%) girls and 202 (53.2%) boys presented %BF of risk, and a larger proportion of %BF of risk was observed in the 1st quintile of the VO2max for both genders. There was inverse association between VO2max and %BF of risk from the 4th quintile (OR 1.84, 95%CI 1.05-3.24) until the 1st quintile (OR 4.74, 95%CI 2.44-9.19) for girls, and from the 2nd quintile (OR 2.99, 95%CI 1.48-6.00) until the 1st quintile (OR 5.60, 95%CI 2.64-11.87) for boys. As analytic highlights, VO2max Cutoff Points for prediction of %BF of risk were ≤40.9 mL/kg-1/min-1 (AUC: 0.65; p<0.001) for girls and ≤44.8 mL/kg-1/min-1 (AUC: 0.66; p<0.001)for boys. CONCLUSIONS: VO2max was inversely associated to the %BF, and VO2max Cutoff Points for prediction of %BF of risk are important results to generate action to fight early obesity.
Ijmert Kant - One of the best experts on this subject based on the ideXlab platform.
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measurement of prolonged fatigue in the working population determination of a Cutoff Point for the checklist individual strength
Journal of Occupational Health Psychology, 2000Co-Authors: Ute Bultmann, Maaike De Vries, Anna Beurskens, Gijs Bleijenberg, J H M M Vercoulen, Ijmert KantAbstract:: In the Netherlands, a large-scale prospective cohort study was started on prolonged fatigue in the working population. The 1st issue that had to be addressed was the determination of a Cutoff Point for fatigue for use in the working population. Fatigue is measured with the Checklist Individual Strength (CIS), a 20-item self-report questionnaire. This article demonstrates the process of decision making in the determination of the Cutoff Point. Total CIS scores were calculated, sensitivity and specificity were compared for potential Cutoff Points, and a receiver operating characteristics analysis was conducted. A CIS total Cutoff Point for fatigue of >76 was determined, with a specificity of 90% and a sensitivity of 73%. Limitations regarding the use of Cutoff Points are discussed. It is concluded that the defined Cutoff Point seems to be appropriate for use in the working population.
Jin Yang - One of the best experts on this subject based on the ideXlab platform.
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Determining the optimal Cutoff Point for lymph node density and its impact on overall survival in children with Wilms' tumor.
Cancer management and research, 2019Co-Authors: Qingting Bu, Jin YangAbstract:Objective: Previous studies showed that the lymph node density (LND) was a predictor of survival in Wilms' tumor (WT). However, the optimal LND Cutoff Point is controversial due to methodological shortcomings of previous studies, and no studies have shown the effect of LND on survival in children with WT. The purpose of this study was to remedy this situation. Methods: We identified 376 children with WT. LND Cutoff Point was determined using the median value, the X-tile program, the survival-tree algorithm, and the time-dependent ROC curve analysis. Survival functions were estimated by the Kaplan-Meier method. We used Cox regression analysis to determine the impact of LND on survival. Smooth curve fitting between relative mortality risk and LND was performed. Results: The LND Cutoff Point was 0.44, 0.65, 0.65, and 0.64 according to the median value, the X-tile program, the survival-tree algorithm, and the time-dependent ROC curve analysis, respectively. The 5-, 10-, and 20-year overall survival rates were 86.9%, 86.9%, and 84.7%, respectively, in the
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determining the optimal Cutoff Point for lymph node density and its impact on overall survival in children with wilms tumor
Cancer management and research, 2019Co-Authors: Qingting Bu, Jin YangAbstract:Objective: Previous studies showed that the lymph node density (LND) was a predictor of survival in Wilms' tumor (WT). However, the optimal LND Cutoff Point is controversial due to methodological shortcomings of previous studies, and no studies have shown the effect of LND on survival in children with WT. The purpose of this study was to remedy this situation. Methods: We identified 376 children with WT. LND Cutoff Point was determined using the median value, the X-tile program, the survival-tree algorithm, and the time-dependent ROC curve analysis. Survival functions were estimated by the Kaplan-Meier method. We used Cox regression analysis to determine the impact of LND on survival. Smooth curve fitting between relative mortality risk and LND was performed. Results: The LND Cutoff Point was 0.44, 0.65, 0.65, and 0.64 according to the median value, the X-tile program, the survival-tree algorithm, and the time-dependent ROC curve analysis, respectively. The 5-, 10-, and 20-year overall survival rates were 86.9%, 86.9%, and 84.7%, respectively, in the <0.44 group and 81.3%, 80.3%, and 80.3%, respectively, in the ≥0.44 group. Survival did not differ significantly between the two groups (P=0.185). The 5-, 10-, and 20-year overall survival rates were 87.8%, 87.8%, and 86.0%, respectively, in the < 0.65 or < 0.64 group and 76.5%, 75.1%, and 75.1%, respectively, in the ≥ 0.65 or ≥ 0.64 group. Children with the high LND had a significantly worse survival (P=0.011) if 0.64 or 0.65 was used for the stratification. LND was a significant predictor for overall survival in the multivariate Cox regression analysis (HR =1.797; 95% CI, 1.043-3.097; P=0.035). Smooth curve fitting suggested that the risk of mortality tended to be ascending with the increase in LND in general. Conclusion: The three methods including the X-tile program, the survival-tree algorithm, and the time-dependent receiver operating characteristic (ROC) curve analysis are equivalent in their ability to stratify patients and clearly better than the median method. The results showed that the optimal LND Cutoff Point was around 0.65 and the LND was a reliable predictor of overall survival in children with WT.
Joseph Wang - One of the best experts on this subject based on the ideXlab platform.
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optimal Cutoff Point of glutamate decarboxylase antibody titers in differentiating two subtypes of adult onset latent autoimmune diabetes
Annals of the New York Academy of Sciences, 2004Co-Authors: Xiayu Li, Liting Yang, Zhiguang Zhou, Gan Huang, Xiang Chen, Joseph WangAbstract:: The optimal Cutoff Point of glutamate decarboxylase antibody (GAD-Ab) titers for differentiating two latent autoimmune diabetes (LADA) subtypes remains unclear. One hundred and forty-five GAD-Ab-positive patients screened from phenotypic type 2 diabetes were diagnosed as LADA. The clinical features were compared among LADA patients with different GAD-Ab titers. The receiver-operating characteristic (ROC) curve was used to evaluate the diagnostic value of GAD-Ab titers and to define the optimal Cutoff Point. The heterogeneity of clinical features in LADA could be discriminated by five GAD-Ab titers, with maximal differences at the titer of 175 U/mL. The ROC curve analysis showed that the optimal Cutoff Point for discriminating two LADA subtypes was at the titer of 175 U/mL, with sensitivity and specificity of 54.5% and 92.1%, respectively. These findings demonstrated that the two clinically distinct subtypes of LADA can be optimally discriminated by the GAD-Ab titers.
