The Experts below are selected from a list of 51 Experts worldwide ranked by ideXlab platform
Rita Lucena - One of the best experts on this subject based on the ideXlab platform.
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The Importance of Methylmalonic Acid Dosage on the Assessment of Patients with Neurological Manifestations Following Bariatric Surgery
Obesity Surgery, 2011Co-Authors: Camilo Vieira, Camila Cosmo, Rita LucenaAbstract:Vitamin B12 or Cyanocobalamin is an important substance that is included in several metabolic pathways. Its Deficiency is a common event after bariatric surgery, decreasing the vitamin B12 absorption after almost all of the stomach and duodenum are eliminated from the digestion process. Neurological manifestations of Cyanocobalamin Deficiency are not uncommon. We report a case of a young woman who developed ataxia, weakness and peripheral neuropathy after bariatric surgery, but with normal value of vitamin B12 dosage. For the diagnosis, it was necessary to dose methylmalonic acid. We discuss the importance of methylmalonic acid dosage after bariatric surgery in patients who present suspect of Cyanocobalamin Deficiency with normal values of this vitamin and the role of proton pump inhibitor use and vitamin supplementation in patients with early neurological presentation.
Camilo Vieira - One of the best experts on this subject based on the ideXlab platform.
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The Importance of Methylmalonic Acid Dosage on the Assessment of Patients with Neurological Manifestations Following Bariatric Surgery
Obesity Surgery, 2011Co-Authors: Camilo Vieira, Camila Cosmo, Rita LucenaAbstract:Vitamin B12 or Cyanocobalamin is an important substance that is included in several metabolic pathways. Its Deficiency is a common event after bariatric surgery, decreasing the vitamin B12 absorption after almost all of the stomach and duodenum are eliminated from the digestion process. Neurological manifestations of Cyanocobalamin Deficiency are not uncommon. We report a case of a young woman who developed ataxia, weakness and peripheral neuropathy after bariatric surgery, but with normal value of vitamin B12 dosage. For the diagnosis, it was necessary to dose methylmalonic acid. We discuss the importance of methylmalonic acid dosage after bariatric surgery in patients who present suspect of Cyanocobalamin Deficiency with normal values of this vitamin and the role of proton pump inhibitor use and vitamin supplementation in patients with early neurological presentation.
Camila Cosmo - One of the best experts on this subject based on the ideXlab platform.
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The Importance of Methylmalonic Acid Dosage on the Assessment of Patients with Neurological Manifestations Following Bariatric Surgery
Obesity Surgery, 2011Co-Authors: Camilo Vieira, Camila Cosmo, Rita LucenaAbstract:Vitamin B12 or Cyanocobalamin is an important substance that is included in several metabolic pathways. Its Deficiency is a common event after bariatric surgery, decreasing the vitamin B12 absorption after almost all of the stomach and duodenum are eliminated from the digestion process. Neurological manifestations of Cyanocobalamin Deficiency are not uncommon. We report a case of a young woman who developed ataxia, weakness and peripheral neuropathy after bariatric surgery, but with normal value of vitamin B12 dosage. For the diagnosis, it was necessary to dose methylmalonic acid. We discuss the importance of methylmalonic acid dosage after bariatric surgery in patients who present suspect of Cyanocobalamin Deficiency with normal values of this vitamin and the role of proton pump inhibitor use and vitamin supplementation in patients with early neurological presentation.
Duhan Himanshu - One of the best experts on this subject based on the ideXlab platform.
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acute psychosis a presentation of Cyanocobalamin Deficiency megaloblastic anemia
Indian Journal of Hematology and Blood Transfusion, 2010Co-Authors: A K Tripathi, Shailendra Prasad Verma, Duhan HimanshuAbstract:Cyanocobalamin Deficiency is not rare in India. Patients present with megaloblastic anemia, pancytopenia and sometimes neuropsychiatric manifestations. Subacute combined degeneration of the cord, peripheral neuropathy, dementia, psychotic depression and paranoid schizophrenia are well reported. We are reporting a case of Cyanocobalamine Deficiency anemia who presented with acute psychosis which readily reversed on Cyanocobalamin replacement.
Medhat N. Nassif - One of the best experts on this subject based on the ideXlab platform.
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Ultrasonographic evaluation to diagnose hepatic lipidosis in Egyptian Zaraibi goats with vitamin B12 Deficiency
Journal of Advanced Research, 2011Co-Authors: Sabry A. El-khodery, Hussein S. Hussein, Mohamed El-boshy, Medhat N. NassifAbstract:Abstract As little is known about the ultrasonographic features of hepatic lipidosis (white liver disease) in goats, this study was undertaken to evaluate the use of ultrasound for the diagnosis of hepatic lipidosis associated with vitamin B12 (Cyanocobalamin) Deficiency in Egyptian Zaraibi goats. A total of 38 goats (28 with weight loss, diarrhoea and anaemia and 10 clinically healthy) were studied. Twenty-one goats were demonstrated to have cobalt and Cyanocobalamin Deficiency (0.33 ± 0.12 μmol/l and 0.17 ± 0.10 μg/l, respectively). Goats were examined with a real-time ultrasound system using a 5-MHz convex transducer. Ultrasound-guided liver biopsies and blood samples were obtained from each animal at examination. Based on the histopathological findings, diseased goats were classified as having mild ( n = 6), moderate ( n = 6) or severe lipidosis ( n = 9). Ultrasonographic-hepatic changes were recorded in 19 (90.4%) out of 21 goats. Severe lipidosis showed diffuse hyper-echogenicity of hepatic parenchyma. However, focal hyper-echoic lesions with various shapes, sizes and positions were visualized in mild and moderate lipidosis. Liver size increased significantly ( P P