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Ana Monteagudo - One of the best experts on this subject based on the ideXlab platform.
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Cystadenofibromas: Can transvaginal ultrasound appearance reduce some surgical interventions?
Journal of clinical ultrasound : JCU, 2014Co-Authors: Steven R. Goldstein, Ilan E. Timor-tritsch, Ana Monteagudo, S. Monda, Dorota PopiolekAbstract:Purpose Cystadenofibromas are benign ovarian neoplasms. Their most typical features on sonography (US) are unilocular cysts with small, shadowing hyperechoic, solid papillae without internal vascularity. In the past, they were virtually always surgically removed to exclude malignancy. This study was undertaken to review the sonographic appearances of benign cystadenomas. Methods We retrospectively reviewed the transvaginal US studies of 32 cases of pathologically proven ovarian Cystadenofibromas. Results Twenty-two of the tumors presented as unilocular cystic structures with one or more solid, hyperechoic, shadowing, mural nodules with no discernible blood flow projecting from the inner cyst wall. Ten lesions were multiloculated with multiple small solid areas, with scant or no blood vessels. Conclusions Cystadenofibromas do not always have a classic appearance on transvaginal US and color Doppler imaging. In our series, however, the majority (69%) presented as unilocular cysts with one or more small solid, avascular projections from the inner cyst wall. These features had 100% reliability for a diagnosis of benign Cystadenofibroma in this small series. Further study is necessary to confirm the reliability of this finding for benign Cystadenofibroma, thus possibly avoiding or minimizing any surgical exploration. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43:393–396, 2015
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OC25.03: Ultrasound appearance of Cystadenofibroma: can we reduce surgical intervention?
Ultrasound in Obstetrics & Gynecology, 2009Co-Authors: Steven R. Goldstein, Ilan E. Timor-tritsch, S. Monda, D. Popliolek, Ana MonteagudoAbstract:Objectives: Transvaginal ultrasound has greatly improved our understanding of ovarian neoplasms. Transvaginal ultrasound has had a very high negative predictive value for excluding ovarian malignancy in cases of unilocular cysts and or minimal septations. Solid components and/or mural nodules have been felt to be a more ominous sonographic finding. Cystadenofibromas are benign ovarian neoplasms that originate from the surface epithelium as well as underlying cortical connective tissue of the ovary. Sonographically they often have solid areas that appear to be papillations coming off the cyst wall (‘‘mural nodules’’) and thus are almost always surgically removed to exclude malignancy. This study was undertaken to determine if any consistent finding of Cystadenofibroma could be discerned thereby increasing the negative predictive value of transvaginal ultrasound and color flow Doppler in identifying them as benign. Material and methods: Over a 6 year period 58 cases of pathologically proven Cystadenofibromas were identified from our hospital’s pathology database. Of these 32 had transvaginal ultrasound with color flow Doppler performed in our imaging facility. The images were analyzed for size, presence of features beyond simple cystic appearance, and presence or absence of blood flow. Results: 22 of the tumors presented as unilocular cystic structures with one or more solid mural nodules projecting from the cyst wall. None of these displayed any discernable blood flow within the solid area. Ten were multi loculated with multiple solid areas and did not follow this more typical classic appearance. Conclusion: Not all cystadenofribromas will look the same on transvaginal ultrasound and color flow Doppler. The majority(69% in our series) presented as unilocular cysts with a small solid non vascular projection from the cyst wall. This particular presentation was virtually pathognomonic and when present seemed to have reliability for benign cystadenofribroma that approached 100% in this small series. Further study is clearly necessary.
Andrea Rockall - One of the best experts on this subject based on the ideXlab platform.
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The MRI features of histologically proven ovarian Cystadenofibromas—an assessment of the morphological and enhancement patterns
European Radiology, 2013Co-Authors: Yen Zhi Tang, Sid Liyanage, Priya Narayanan, Anju Sahdev, Aslam Sohaib, Naveena Singh, Andrea RockallAbstract:Objectives To assess the morphological and enhancement features of histologically proven Cystadenofibromas (CAFs) on magnetic resonance imaging (MRI). Methods Forty-seven histologically proven CAFs (42 benign, five borderline) were retrospectively reviewed. One benign CAF had a synchronous adenocarcinoma in the same ovary. The morphological, signal and enhancement characteristics on MRI were recorded. Results The mean long axis diameter of the CAFs was 80 mm. The contralateral ovary was abnormal in 45 % of cases. A solid component was seen in 85 %, which returned low T2-weighted signal in 75 % of CAFs. Septa were seen in 74 % and one CAF was purely cystic. The majority of solid components and septa demonstrated enhancement that was less than the myometrium. Wash-in rates (WIR) of the solid tissue were available for measurement in nine patients with an average WIR of 3.2 l/s. Conclusion This is the largest series describing MRI appearances of histologically proven CAFs. They are typically complex adnexal lesions containing septa, cystic components and solid tissue. The majority of solid components demonstrate low T2 signal and minimal enhancement. Almost half of the cases have an abnormal contralateral ovary. Key Points • Cystadenofibromas are complex adnexal lesions containing septa, cystic, and solid components. • Some MRI features of Cystadenofibromas overlap with those of malignant ovarian lesions. • Almost 50 % of patients with a Cystadenofibroma have an abnormal contralateral ovary. • Most contralateral lesions are benign, but we found four borderline tumours.
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The MRI features of histologically proven ovarian Cystadenofibromas-an assessment of the morphological and enhancement patterns.
European radiology, 2012Co-Authors: Yen Zhi Tang, Sid Liyanage, Priya Narayanan, Anju Sahdev, Aslam Sohaib, Naveena Singh, Andrea RockallAbstract:Objectives To assess the morphological and enhancement features of histologically proven Cystadenofibromas (CAFs) on magnetic resonance imaging (MRI).
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The MRI features of ovarian Cystadenofibromas (CAFs)- an assessment of the morphological and enhancement patterns with histological correlation
2012Co-Authors: Yen Zhi Tang, Priya Narayanan, Anju Sahdev, Sidath H. Liyanage, S.a. Sohaib, Andrea RockallAbstract:Poster: "ECR 2012 / C-1743 / The MRI features of ovarian Cystadenofibromas (CAFs)- an assessment of the morphological and enhancement patterns with histological correlation" by: "Y. Z. Tang1, S. H. Liyanage1, P. Narayanan1, A. Sahdev1, S. A. Sohaib2, A. G. Rockall1; 1London/UK, 2Sutton/UK"
Steven R. Goldstein - One of the best experts on this subject based on the ideXlab platform.
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Cystadenofibromas: Can transvaginal ultrasound appearance reduce some surgical interventions?
Journal of clinical ultrasound : JCU, 2014Co-Authors: Steven R. Goldstein, Ilan E. Timor-tritsch, Ana Monteagudo, S. Monda, Dorota PopiolekAbstract:Purpose Cystadenofibromas are benign ovarian neoplasms. Their most typical features on sonography (US) are unilocular cysts with small, shadowing hyperechoic, solid papillae without internal vascularity. In the past, they were virtually always surgically removed to exclude malignancy. This study was undertaken to review the sonographic appearances of benign cystadenomas. Methods We retrospectively reviewed the transvaginal US studies of 32 cases of pathologically proven ovarian Cystadenofibromas. Results Twenty-two of the tumors presented as unilocular cystic structures with one or more solid, hyperechoic, shadowing, mural nodules with no discernible blood flow projecting from the inner cyst wall. Ten lesions were multiloculated with multiple small solid areas, with scant or no blood vessels. Conclusions Cystadenofibromas do not always have a classic appearance on transvaginal US and color Doppler imaging. In our series, however, the majority (69%) presented as unilocular cysts with one or more small solid, avascular projections from the inner cyst wall. These features had 100% reliability for a diagnosis of benign Cystadenofibroma in this small series. Further study is necessary to confirm the reliability of this finding for benign Cystadenofibroma, thus possibly avoiding or minimizing any surgical exploration. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43:393–396, 2015
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OC25.03: Ultrasound appearance of Cystadenofibroma: can we reduce surgical intervention?
Ultrasound in Obstetrics & Gynecology, 2009Co-Authors: Steven R. Goldstein, Ilan E. Timor-tritsch, S. Monda, D. Popliolek, Ana MonteagudoAbstract:Objectives: Transvaginal ultrasound has greatly improved our understanding of ovarian neoplasms. Transvaginal ultrasound has had a very high negative predictive value for excluding ovarian malignancy in cases of unilocular cysts and or minimal septations. Solid components and/or mural nodules have been felt to be a more ominous sonographic finding. Cystadenofibromas are benign ovarian neoplasms that originate from the surface epithelium as well as underlying cortical connective tissue of the ovary. Sonographically they often have solid areas that appear to be papillations coming off the cyst wall (‘‘mural nodules’’) and thus are almost always surgically removed to exclude malignancy. This study was undertaken to determine if any consistent finding of Cystadenofibroma could be discerned thereby increasing the negative predictive value of transvaginal ultrasound and color flow Doppler in identifying them as benign. Material and methods: Over a 6 year period 58 cases of pathologically proven Cystadenofibromas were identified from our hospital’s pathology database. Of these 32 had transvaginal ultrasound with color flow Doppler performed in our imaging facility. The images were analyzed for size, presence of features beyond simple cystic appearance, and presence or absence of blood flow. Results: 22 of the tumors presented as unilocular cystic structures with one or more solid mural nodules projecting from the cyst wall. None of these displayed any discernable blood flow within the solid area. Ten were multi loculated with multiple solid areas and did not follow this more typical classic appearance. Conclusion: Not all cystadenofribromas will look the same on transvaginal ultrasound and color flow Doppler. The majority(69% in our series) presented as unilocular cysts with a small solid non vascular projection from the cyst wall. This particular presentation was virtually pathognomonic and when present seemed to have reliability for benign cystadenofribroma that approached 100% in this small series. Further study is clearly necessary.
Yen Zhi Tang - One of the best experts on this subject based on the ideXlab platform.
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The MRI features of histologically proven ovarian Cystadenofibromas—an assessment of the morphological and enhancement patterns
European Radiology, 2013Co-Authors: Yen Zhi Tang, Sid Liyanage, Priya Narayanan, Anju Sahdev, Aslam Sohaib, Naveena Singh, Andrea RockallAbstract:Objectives To assess the morphological and enhancement features of histologically proven Cystadenofibromas (CAFs) on magnetic resonance imaging (MRI). Methods Forty-seven histologically proven CAFs (42 benign, five borderline) were retrospectively reviewed. One benign CAF had a synchronous adenocarcinoma in the same ovary. The morphological, signal and enhancement characteristics on MRI were recorded. Results The mean long axis diameter of the CAFs was 80 mm. The contralateral ovary was abnormal in 45 % of cases. A solid component was seen in 85 %, which returned low T2-weighted signal in 75 % of CAFs. Septa were seen in 74 % and one CAF was purely cystic. The majority of solid components and septa demonstrated enhancement that was less than the myometrium. Wash-in rates (WIR) of the solid tissue were available for measurement in nine patients with an average WIR of 3.2 l/s. Conclusion This is the largest series describing MRI appearances of histologically proven CAFs. They are typically complex adnexal lesions containing septa, cystic components and solid tissue. The majority of solid components demonstrate low T2 signal and minimal enhancement. Almost half of the cases have an abnormal contralateral ovary. Key Points • Cystadenofibromas are complex adnexal lesions containing septa, cystic, and solid components. • Some MRI features of Cystadenofibromas overlap with those of malignant ovarian lesions. • Almost 50 % of patients with a Cystadenofibroma have an abnormal contralateral ovary. • Most contralateral lesions are benign, but we found four borderline tumours.
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The MRI features of histologically proven ovarian Cystadenofibromas-an assessment of the morphological and enhancement patterns.
European radiology, 2012Co-Authors: Yen Zhi Tang, Sid Liyanage, Priya Narayanan, Anju Sahdev, Aslam Sohaib, Naveena Singh, Andrea RockallAbstract:Objectives To assess the morphological and enhancement features of histologically proven Cystadenofibromas (CAFs) on magnetic resonance imaging (MRI).
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The MRI features of ovarian Cystadenofibromas (CAFs)- an assessment of the morphological and enhancement patterns with histological correlation
2012Co-Authors: Yen Zhi Tang, Priya Narayanan, Anju Sahdev, Sidath H. Liyanage, S.a. Sohaib, Andrea RockallAbstract:Poster: "ECR 2012 / C-1743 / The MRI features of ovarian Cystadenofibromas (CAFs)- an assessment of the morphological and enhancement patterns with histological correlation" by: "Y. Z. Tang1, S. H. Liyanage1, P. Narayanan1, A. Sahdev1, S. A. Sohaib2, A. G. Rockall1; 1London/UK, 2Sutton/UK"
Kamil Kumanlioglu - One of the best experts on this subject based on the ideXlab platform.
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radioiodine accumulation in a large adnexal Cystadenofibroma
Thyroid, 2010Co-Authors: Omer Turker, Ismail Dogan, Kamil KumanliogluAbstract:Background: Posttherapy or diagnostic whole-body radioiodine (131I) scans are conducted to observe metastases of differentiated thyroid carcinomas. Sometimes, false-positive scans occur due a varie...
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Radioiodine Accumulation in a Large Adnexal Cystadenofibroma
Thyroid : official journal of the American Thyroid Association, 2010Co-Authors: Omer Turker, Ismail Dogan, Kamil KumanliogluAbstract:Background: Posttherapy or diagnostic whole-body radioiodine (131I) scans are conducted to observe metastases of differentiated thyroid carcinomas. Sometimes, false-positive scans occur due a variety of lesions. Here we report a patient with marked radioiodine accumulation in a large adnexal Cystadenofibroma, a benign ovarian tumor. Summary: A 51-year-old woman underwent subtotal thyroidectomy due to an enlarged-multinodular goiter that caused mild compression to trachea. In her preoperative neck ultrasonography, there were mixed cystic-solid nodules without suspicious ultrasound features that were smaller than 1 cm. Pathologic examination revealed multifocal papillary thyroid carcinoma. The residual thyroid tissue was ablated with 3.7 GBq radioiodine (131I) when the serum thyroglobulin concentration was 28.7 ng/mL and the serum thyroid-stimulating hormone level was 50 μIU/mL. A posttherapy whole-body scan on the 10th day after ablation revealed well-demarcated, circumscribed radioiodine uptake in the rig...
