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Samir Patel - One of the best experts on this subject based on the ideXlab platform.
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Cystoid Macular Edema retinal detachment and glaucoma after nd yag laser posterior capsulotomy
American Journal of Ophthalmology, 1991Co-Authors: Roger F Steinert, Carmen A Puliafito, Sanjiv R Kumar, Scott D Dudak, Samir PatelAbstract:Abstract A series of 897 Nd:YAG laser posterior capsulotomies were reviewed for the complications of Cystoid Macular Edema, retinal detachment, new onset of glaucoma, and worsened preexisting glaucoma. After Nd:YAG capsulotomy, 11 patients (1.23%; 95% confidence interval, 0.51% to 1.95%) developed Cystoid Macular Edema and eight patients (0.89%; 95% confidence interval, 0.28% to 1.5%) developed a retinal detachment. The new onset of glaucoma was observed in seven patients (0.78%; 95% confidence interval, 0.20% to 1.36%). Five patients (0.56%; 95% confidence interval, 0.07% to 1.05%) with preexisting glaucoma had persistent worsening of their glaucoma. Most patients with a complication had no identifiable risk factors in common. The numbers of laser pulses and energy delivered were not risk factors. Retinal detachment and Cystoid Macular Edema developed most often many months after capsulotomy and many months to years after the cataract surgery. Patients undergoing Nd:YAG laser capsulotomy therefore require ongoing medical observation to detect and treat these serious complications.
Roger F Steinert - One of the best experts on this subject based on the ideXlab platform.
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Cystoid Macular Edema retinal detachment and glaucoma after nd yag laser posterior capsulotomy
American Journal of Ophthalmology, 1991Co-Authors: Roger F Steinert, Carmen A Puliafito, Sanjiv R Kumar, Scott D Dudak, Samir PatelAbstract:Abstract A series of 897 Nd:YAG laser posterior capsulotomies were reviewed for the complications of Cystoid Macular Edema, retinal detachment, new onset of glaucoma, and worsened preexisting glaucoma. After Nd:YAG capsulotomy, 11 patients (1.23%; 95% confidence interval, 0.51% to 1.95%) developed Cystoid Macular Edema and eight patients (0.89%; 95% confidence interval, 0.28% to 1.5%) developed a retinal detachment. The new onset of glaucoma was observed in seven patients (0.78%; 95% confidence interval, 0.20% to 1.36%). Five patients (0.56%; 95% confidence interval, 0.07% to 1.05%) with preexisting glaucoma had persistent worsening of their glaucoma. Most patients with a complication had no identifiable risk factors in common. The numbers of laser pulses and energy delivered were not risk factors. Retinal detachment and Cystoid Macular Edema developed most often many months after capsulotomy and many months to years after the cataract surgery. Patients undergoing Nd:YAG laser capsulotomy therefore require ongoing medical observation to detect and treat these serious complications.
Sharon Fekrat - One of the best experts on this subject based on the ideXlab platform.
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intravitreal triamcinolone acetonide in eyes with Cystoid Macular Edema associated with central retinal vein occlusion
American Journal of Ophthalmology, 2003Co-Authors: Carl H Park, Glenn J Jaffe, Sharon FekratAbstract:Abstract Purpose To evaluate treatment of Cystoid Macular Edema associated with central retinal vein occlusion with intravitreal triamcinolone acetonide. Methods This study included 10 eyes of nine patients with perfused central retinal vein occlusion with visual acuity of 20/50 or worse. Following baseline evaluation, including best-corrected visual acuity, intraocular pressure (IOP), fluorescein angiography, and volumetric optical coherence tomography (VOCT), triamcinolone acetonide (4 mg in 0.1 ml) was injected into the vitreous cavity. Results Mean duration from the time of diagnosis to the intravitreal injection was 15.4 months. All 10 eyes demonstrated biomicroscopic improvement in Cystoid Macular Edema with corresponding improvement in VOCT measurements from a mean of 4.2 mm 3 preinjection to a mean of 2.6 mm 3 at last follow-up ( P P = .01). Six eyes (60%) were ≥20/50. There were no significant complications. Three eyes (30%) without previous history of glaucoma required initiation of topical aqueous suppressant therapy for IOP elevation at last follow-up. One eye with a previous history of open-angle glaucoma required a trabeculectomy. Conclusion Intravitreal injection of triamcinolone acetonide appears to be effective in reducing Cystoid Macular Edema associated with central retinal vein occlusion. This reduction often corresponded to an improvement in visual acuity. Further evaluation is warranted to assess its safety and efficacy in these eyes.
Michal Kramer - One of the best experts on this subject based on the ideXlab platform.
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Anti-TNF-α agents for refractory Cystoid Macular Edema associated with noninfectious uveitis
Graefe's Archive for Clinical and Experimental Ophthalmology, 2014Co-Authors: Michal Schaap-fogler, Ronit Friling, Ethan Priel, Radgonde Amer, Michal KramerAbstract:BackgroundThe use of anti-tumor necrosis factor (TNF)-α agents for uveitis has been increasing since the first efficacy studies in 2004. However, information on their specific role in cystic Macular Edema remains sparse. The aim of this study was to evaluate the efficacy of anti-TNF-α agents for the treatment of uveitis-related refractory Cystoid Macular Edema.MethodsThe files of 23 consecutive patients treated for Cystoid Macular Edema at the uveitis services of two tertiary medical centers in 2006-2011 were reviewed for demographic data, visual acuity, and optical coherence tomography measurements at baseline and 3, 6, and 12 months after treatment. Changes in mean visual acuity and Macular thickness were analyzed. Findings were compared between patients treated with a conventional immunosuppressive regimen only (n = 18, 27 eyes) and patients treated with an anti-TNF-α agent after proving refractory to conventional treatment (n = 9, 15 eyes).ResultsMean duration of Cystoid Macular Edema before initiation of anti-TNF-α therapy was 12 ± 8 months. The two groups had similar baseline values of mean central Macular thickness and visual acuity. Significant improvement in Macular thickness was noted at 3 months in both groups, with a maximal effect at 6 months for the anti-TNF-α group (p = 0.002). Maximal improvement in visual acuity was achieved at 3 months in both groups, with a reduced effect towards 12 months. Mean visual acuity at 12 months was similar in both groups.ConclusionsAnti-TNF-α agents may serve as an effective lasting treatment for long-standing refractory uveitis-related Cystoid Macular Edema. Their role as first-line therapy in this setting warrants further investigation.
Lee M. Jampol - One of the best experts on this subject based on the ideXlab platform.
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Cystoid Macular Edema IN THE SETTING OF PRIMARY VITREORETINAL LYMPHOMA.
Retinal Cases & Brief Reports, 2018Co-Authors: Gábor Gy Deák, Scott R. Sneed, Lee M. JampolAbstract:PURPOSE To present a rare case of primary vitreoretinal lymphoma presenting with Cystoid Macular Edema without previous surgical intervention or radiotherapy. METHODS Retrospective chart review of one patient. RESULTS A 74-year-old patient was seen with a history of cataract surgery in 1 eye and presumed ocular inflammation with recurrent Cystoid Macular Edema in both eyes. On examination, subretinal pigment epithelial and intraretinal infiltrates raised the suspicion of primary vitreoretinal lymphoma despite the unusual presentation with Cystoid Macular Edema. A magnetic resonance imaging and brain biopsy confirmed the diagnosis of vitreoretinal lymphoma in the setting of central nervous system lymphoma. CONCLUSION Primary vitreoretinal lymphoma can present with Cystoid Macular Edema in rare cases.
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Near-UV radiation from the operating microscope and pseudophakic Cystoid Macular Edema.
Archives of Ophthalmology, 2016Co-Authors: Lee M. Jampol, Manus C. Kraff, Donald R. Sanders, Kenneth R. Alexander, Howard L. LiebermanAbstract:• We performed a prospective randomized study of 297 patients to determine the effect of a UV-blocking filter on the operating microscope on the angiographic incidence of Cystoid Macular Edema in patients undergoing extracapsular surgery with implantation of a posterior chamber lens. Patients were randomly allocated preoperatively to two groups undergoing surgery with or without a UV filter in place. Of the 297 patients, 205 had angiograms readable for the presence or absence of Cystoid Macular Edema. The incidence of aphakic Cystoid Macular Edema in patients without the filter was 21% v 17.3% in the group with a filter. This difference was not significant. The presence of a UV-blocking filter on the operating microscope makes no difference in the angiographic incidence of Cystoid Macular Edema or the visual outcome in these cases.
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PHARMACOLOGIC THERAPY OF PSEUDOPHAKIC Cystoid Macular Edema: 2010 Update
Retina-the Journal of Retinal and Vitreous Diseases, 2016Co-Authors: Heather N. Shelsta, Lee M. JampolAbstract:Purpose:To review the current management and pharmacologic treatment of pseudophakic Cystoid Macular Edema.Methods:Systematic review of currently accepted treatment modalities for pseudophakic Cystoid Macular Edema. Main outcome measures include visual acuity and retinal thickness measurement by opt
