The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform
Matthew T. Olson - One of the best experts on this subject based on the ideXlab platform.
-
© American Society for Clinical Pathology Anatomic Pathology / Cytotechnologist On-Site Adequacy Evaluation of Thyroid FNA Cytotechnologist-Attended On-Site Adequacy Evaluation of Thyroid Fine-Needle Aspiration Comparison With Cytopathologists and Co
2016Co-Authors: Matthew T. Olson, Armanda D. Tatsas, Syed Z. Ali, Key Words, On-site Thyroid, Fna Cytotechnologist CytopathologistAbstract:A b s t r a c t Recent increases in the number of thyroid fine-needle aspiration (FNAs) biopsies and the popularity of on-site evaluation for adequacy (OSEA) have led many practices, including ours, to rely on Cytotechnologists for performing OSEA. We retrospectively analyzed the accuracy of a Cytotechnologist against that of a cytopathologist in performing OSEA and making the final diagnosis. Of 2,261 thyroid FNA specimens evaluated over a 33-month period under ultrasound guidance with OSEA, the Cytotechnologist attended 64.7 % (1,462/2,261) of the procedures whereas the cytopathologist attended 35.3 % (799/2,261). There was no difference in the adequacy downgrade rate for Cytotechnologists compared with that for cytopathologists during this study period (4.1 % vs 5.0 % downgrade rate, P =.33). Regardless of who rendered the OSEA, subadequate specimens had a higher rate of indeterminate diagnosis (25.2%) than those specimens deemed adequate at the time of OSEA (11.9%, P =.00001). These results indicate that the accuracy of Cytotechnologists is comparable with that of cytopathologists in conducting OSEA of the thyroid. Fine-needle aspiration (FNA) biopsy of the thyroid is a valuable and time-proven diagnostic modality for the assess-ment of thyroid nodules.1-3 Despite its widespread use, the procedure has the potential for yielding material that is inad-equate or suboptimal for rendering a diagnosis. A shortage of cellularity is a common factor leading to the inability to make a definitively malignant or benign diagnosis. For this reason, adequacy evaluation is a key component of cytopathologic evaluation of thyroid FNA and is included as a component o
-
Cytotechnologist Performance for Screening Hürthle Cell Atypia in Indeterminate Thyroid Fine-Needle Aspirates.
Acta cytologica, 2015Co-Authors: Christopher J Vandenbussche, Syed Z. Ali, Christina Adams, Matthew T. OlsonAbstract:Objectives: We have previously shown that specimens diagnosed as containing Hurthle cells have a 12% chance of being malignant if they are classified as atypia of undetermined significance (AUS-HC). The identification of Hurthle cells by Cytotechnologists (CTs) during screening can improve cytopathologist efficiency and may prevent diagnostic errors due to the oversights of focal findings. Here, we examine the performance of our institutional CTs when screening for Hurthle cell atypia in thyroid fine-needle aspiration (FNA) specimens. Study Design: Information on 8,814 thyroid cytopathology specimens was retrieved for a 10-year period. Specimens were screened by 1 of 11 CTs. A subsample of cases was categorized either as AUS-HC or suspicious for Hurthle cell neoplasm. Results: AUS-HC screening diagnoses were more likely to be downgraded to benign but less likely to be upgraded compared to AUS diagnoses with nuclear or microfollicular atypia. AUS-HC represents almost all papillary thyroid carcinoma (PTC) screening diagnoses downgraded to the AUS category, which suggests that even low levels of Hurthle cell atypia can result in PTC being included in the differential diagnosis. Conclusion: Overall, there are few major discrepancies between CT and pathologist diagnoses for specimens containing Hurthle cell atypia.
-
Accuracy of Cytotechnologist Evaluation of Specimen Adequacy and Screening Interpretation of Malignancy in Fine-Needle Aspiration of the Liver
Acta cytologica, 2014Co-Authors: Aadil Ahmed, Syed Z. Ali, Anna Novak, Aisha Farhat Sheerin, Thiraphon Boonyaarunnate, Matthew T. OlsonAbstract:Objective: To evaluate the performance of Cytotechnologists in assessing the adequacy and accuracy of the preliminary diagnosis for fine-needle aspirates of the liver. Study Design: We retrospectively analyzed 10 years of data and found 589 cases of ultrasound-guided fine-needle aspiration (FNA) of the liver with on-site evaluation of adequacy (OSEA). All the OSEA were performed by the cytopathologist because OSEA of liver FNA is not performed by Cytotechnologists at our institution at present. After OSEA, the material was seen by Cytotechnologists who rendered an adequacy assessment and preliminary diagnosis. We calculated the adequacy and accuracy statistics and compared the performance of the Cytotechnologists with the OSEA and final interpretation. Results: There was no statistically significant difference in adequacy downgrade rate for Cytotechnologist versus cytopathologist assessment during the study period (5 vs. 3%, p = 0.06). A total agreement of 88% was noted in overall diagnosis with 97% agreement in malignant cases. Conclusion: Cytotechnologists assess the adequacy of liver FNA accurately and there is therefore potential for them to perform OSEA for liver FNA.
-
Cytotechnologist performance for detecting nuclear atypia in indeterminate thyroid fine needle aspirates
Acta Cytologica, 2014Co-Authors: Christopher J Vandenbussche, Christina Adams, Matthew T. OlsonAbstract:Introduction: The thyroid gland is arguably the fastest growing anatomic site for fine needle aspiration (FNA). With the increase of thyroid cases, a reevaluation
-
Cytotechnologist-attended on-site evaluation of adequacy for fine-needle aspiration of bone and soft tissue neoplasms.
Journal of the American Society of Cytopathology, 2013Co-Authors: Matthew T. Olson, Anna Novak, Thiraphon Boonyaarunnate, Hinna Shahid, John Kirby, Syed Z. AliAbstract:Introduction On-site evaluation of adequacy (OSEA) is commonly used to increase the adequacy rate of fine-needle aspiration (FNA) procedures. OSEA is increasingly necessary with the widespread use of image-guided procedures, which are expensive to perform and repeat. The increased demand for OSEA has prompted an increasing reliance on Cytotechnologists for OSEA in many practices, including ours. However, the performance of Cytotechnologists has not been compared with that of cytopathologists for OSEA in FNA of bone and soft tissue tumors. Materials and methods We retrospectively analyzed 10 years of data in which both Cytotechnologists and cytopathologists performed OSEA for 632 bone and soft tissue tumor FNA. We calculated adequacy and accuracy statistics in conjunction with other variables including imaging modality, biopsy site, accompanying core biopsy, tissue type, final diagnosis, and number of smears. Results Of the 632 bone and soft tissue tumor FNA procedures, OSEA was performed in 223 (35.3%) by Cytotechnologists and in 409 (64.7%) by cytopathologists. There was no difference in the adequacy downgrade rate for Cytotechnologists versus cytopathologists during this study period (4.5 versus 2.4%, P = 0.23). The adequacy rates for procedures in which OSEA was performed by Cytotechnologists and cytopathologists did not differ significantly (78.9 versus 84.1%, P = 0.13). Conclusions Cytotechnologists and cytopathologists are comparably accurate in OSEA of bone and soft tissue neoplasms.
Syed Z. Ali - One of the best experts on this subject based on the ideXlab platform.
-
© American Society for Clinical Pathology Anatomic Pathology / Cytotechnologist On-Site Adequacy Evaluation of Thyroid FNA Cytotechnologist-Attended On-Site Adequacy Evaluation of Thyroid Fine-Needle Aspiration Comparison With Cytopathologists and Co
2016Co-Authors: Matthew T. Olson, Armanda D. Tatsas, Syed Z. Ali, Key Words, On-site Thyroid, Fna Cytotechnologist CytopathologistAbstract:A b s t r a c t Recent increases in the number of thyroid fine-needle aspiration (FNAs) biopsies and the popularity of on-site evaluation for adequacy (OSEA) have led many practices, including ours, to rely on Cytotechnologists for performing OSEA. We retrospectively analyzed the accuracy of a Cytotechnologist against that of a cytopathologist in performing OSEA and making the final diagnosis. Of 2,261 thyroid FNA specimens evaluated over a 33-month period under ultrasound guidance with OSEA, the Cytotechnologist attended 64.7 % (1,462/2,261) of the procedures whereas the cytopathologist attended 35.3 % (799/2,261). There was no difference in the adequacy downgrade rate for Cytotechnologists compared with that for cytopathologists during this study period (4.1 % vs 5.0 % downgrade rate, P =.33). Regardless of who rendered the OSEA, subadequate specimens had a higher rate of indeterminate diagnosis (25.2%) than those specimens deemed adequate at the time of OSEA (11.9%, P =.00001). These results indicate that the accuracy of Cytotechnologists is comparable with that of cytopathologists in conducting OSEA of the thyroid. Fine-needle aspiration (FNA) biopsy of the thyroid is a valuable and time-proven diagnostic modality for the assess-ment of thyroid nodules.1-3 Despite its widespread use, the procedure has the potential for yielding material that is inad-equate or suboptimal for rendering a diagnosis. A shortage of cellularity is a common factor leading to the inability to make a definitively malignant or benign diagnosis. For this reason, adequacy evaluation is a key component of cytopathologic evaluation of thyroid FNA and is included as a component o
-
Cytotechnologist Performance for Screening Hürthle Cell Atypia in Indeterminate Thyroid Fine-Needle Aspirates.
Acta cytologica, 2015Co-Authors: Christopher J Vandenbussche, Syed Z. Ali, Christina Adams, Matthew T. OlsonAbstract:Objectives: We have previously shown that specimens diagnosed as containing Hurthle cells have a 12% chance of being malignant if they are classified as atypia of undetermined significance (AUS-HC). The identification of Hurthle cells by Cytotechnologists (CTs) during screening can improve cytopathologist efficiency and may prevent diagnostic errors due to the oversights of focal findings. Here, we examine the performance of our institutional CTs when screening for Hurthle cell atypia in thyroid fine-needle aspiration (FNA) specimens. Study Design: Information on 8,814 thyroid cytopathology specimens was retrieved for a 10-year period. Specimens were screened by 1 of 11 CTs. A subsample of cases was categorized either as AUS-HC or suspicious for Hurthle cell neoplasm. Results: AUS-HC screening diagnoses were more likely to be downgraded to benign but less likely to be upgraded compared to AUS diagnoses with nuclear or microfollicular atypia. AUS-HC represents almost all papillary thyroid carcinoma (PTC) screening diagnoses downgraded to the AUS category, which suggests that even low levels of Hurthle cell atypia can result in PTC being included in the differential diagnosis. Conclusion: Overall, there are few major discrepancies between CT and pathologist diagnoses for specimens containing Hurthle cell atypia.
-
Accuracy of Cytotechnologist Evaluation of Specimen Adequacy and Screening Interpretation of Malignancy in Fine-Needle Aspiration of the Liver
Acta cytologica, 2014Co-Authors: Aadil Ahmed, Syed Z. Ali, Anna Novak, Aisha Farhat Sheerin, Thiraphon Boonyaarunnate, Matthew T. OlsonAbstract:Objective: To evaluate the performance of Cytotechnologists in assessing the adequacy and accuracy of the preliminary diagnosis for fine-needle aspirates of the liver. Study Design: We retrospectively analyzed 10 years of data and found 589 cases of ultrasound-guided fine-needle aspiration (FNA) of the liver with on-site evaluation of adequacy (OSEA). All the OSEA were performed by the cytopathologist because OSEA of liver FNA is not performed by Cytotechnologists at our institution at present. After OSEA, the material was seen by Cytotechnologists who rendered an adequacy assessment and preliminary diagnosis. We calculated the adequacy and accuracy statistics and compared the performance of the Cytotechnologists with the OSEA and final interpretation. Results: There was no statistically significant difference in adequacy downgrade rate for Cytotechnologist versus cytopathologist assessment during the study period (5 vs. 3%, p = 0.06). A total agreement of 88% was noted in overall diagnosis with 97% agreement in malignant cases. Conclusion: Cytotechnologists assess the adequacy of liver FNA accurately and there is therefore potential for them to perform OSEA for liver FNA.
-
Cytotechnologist-attended on-site evaluation of adequacy for fine-needle aspiration of bone and soft tissue neoplasms.
Journal of the American Society of Cytopathology, 2013Co-Authors: Matthew T. Olson, Anna Novak, Thiraphon Boonyaarunnate, Hinna Shahid, John Kirby, Syed Z. AliAbstract:Introduction On-site evaluation of adequacy (OSEA) is commonly used to increase the adequacy rate of fine-needle aspiration (FNA) procedures. OSEA is increasingly necessary with the widespread use of image-guided procedures, which are expensive to perform and repeat. The increased demand for OSEA has prompted an increasing reliance on Cytotechnologists for OSEA in many practices, including ours. However, the performance of Cytotechnologists has not been compared with that of cytopathologists for OSEA in FNA of bone and soft tissue tumors. Materials and methods We retrospectively analyzed 10 years of data in which both Cytotechnologists and cytopathologists performed OSEA for 632 bone and soft tissue tumor FNA. We calculated adequacy and accuracy statistics in conjunction with other variables including imaging modality, biopsy site, accompanying core biopsy, tissue type, final diagnosis, and number of smears. Results Of the 632 bone and soft tissue tumor FNA procedures, OSEA was performed in 223 (35.3%) by Cytotechnologists and in 409 (64.7%) by cytopathologists. There was no difference in the adequacy downgrade rate for Cytotechnologists versus cytopathologists during this study period (4.5 versus 2.4%, P = 0.23). The adequacy rates for procedures in which OSEA was performed by Cytotechnologists and cytopathologists did not differ significantly (78.9 versus 84.1%, P = 0.13). Conclusions Cytotechnologists and cytopathologists are comparably accurate in OSEA of bone and soft tissue neoplasms.
-
Cytotechnologist-attended on-site evaluation of adequacy for metastatic disease involving bone and soft tissue.
Acta cytologica, 2013Co-Authors: Matthew T. Olson, Anna Novak, Thiraphon Boonyaarunnate, Hinna Shahid, John Kirby, Syed Z. AliAbstract:Introduction: Image-guided fine needle aspiration (FNA) of the musculoskeletal system is expensive to perform and repeat, so on-site evaluation of adequacy (OSEA) is increasingly used to ensure an optimal sample. Metastatic disease to the musculoskeletal system is not uncommon and often requires OSEA when sampled. At large academic centers, Cytotechnologists have filled the increased demand for OSEA. However, the performance of Cytotechnologists has not been compared with that of cytopathologists for OSEA in FNA of metastatic disease involving bone and soft tissue. Methods: We retrospectively analyzed 10 years of data in which both Cytotechnologists and cytopathologists performed OSEA for 1,995 FNAs of bone and soft tissue sites in which metastatic malignancy was suspected or found. We calculated adequacy and accuracy statistics in conjunction with other variables including imaging modality, biopsy site, accompanying core biopsy, tissue type, final diagnosis, and number of smears. Results: A total of 1,995 aspirates of metastatic disease carcinoma, melanoma or lymphoma to bone or soft tissue had OSEA performed by Cytotechnologists (681, 33.7%) or cytopathologists (1,314, 66.3%). The adequacy downgrade rate was statistically equivalent (4.1 vs. 3.6%; p = 0.64). Conclusion: Cytotechnologists and cytopathologists perform with reasonable equivalence at OSEA of aspirates from metastatic carcinoma, melanoma or lymphoma involving bone or soft tissue.
Anna Novak - One of the best experts on this subject based on the ideXlab platform.
-
Accuracy of Cytotechnologist Evaluation of Specimen Adequacy and Screening Interpretation of Malignancy in Fine-Needle Aspiration of the Liver
Acta cytologica, 2014Co-Authors: Aadil Ahmed, Syed Z. Ali, Anna Novak, Aisha Farhat Sheerin, Thiraphon Boonyaarunnate, Matthew T. OlsonAbstract:Objective: To evaluate the performance of Cytotechnologists in assessing the adequacy and accuracy of the preliminary diagnosis for fine-needle aspirates of the liver. Study Design: We retrospectively analyzed 10 years of data and found 589 cases of ultrasound-guided fine-needle aspiration (FNA) of the liver with on-site evaluation of adequacy (OSEA). All the OSEA were performed by the cytopathologist because OSEA of liver FNA is not performed by Cytotechnologists at our institution at present. After OSEA, the material was seen by Cytotechnologists who rendered an adequacy assessment and preliminary diagnosis. We calculated the adequacy and accuracy statistics and compared the performance of the Cytotechnologists with the OSEA and final interpretation. Results: There was no statistically significant difference in adequacy downgrade rate for Cytotechnologist versus cytopathologist assessment during the study period (5 vs. 3%, p = 0.06). A total agreement of 88% was noted in overall diagnosis with 97% agreement in malignant cases. Conclusion: Cytotechnologists assess the adequacy of liver FNA accurately and there is therefore potential for them to perform OSEA for liver FNA.
-
Cytotechnologist-attended on-site evaluation of adequacy for fine-needle aspiration of bone and soft tissue neoplasms.
Journal of the American Society of Cytopathology, 2013Co-Authors: Matthew T. Olson, Anna Novak, Thiraphon Boonyaarunnate, Hinna Shahid, John Kirby, Syed Z. AliAbstract:Introduction On-site evaluation of adequacy (OSEA) is commonly used to increase the adequacy rate of fine-needle aspiration (FNA) procedures. OSEA is increasingly necessary with the widespread use of image-guided procedures, which are expensive to perform and repeat. The increased demand for OSEA has prompted an increasing reliance on Cytotechnologists for OSEA in many practices, including ours. However, the performance of Cytotechnologists has not been compared with that of cytopathologists for OSEA in FNA of bone and soft tissue tumors. Materials and methods We retrospectively analyzed 10 years of data in which both Cytotechnologists and cytopathologists performed OSEA for 632 bone and soft tissue tumor FNA. We calculated adequacy and accuracy statistics in conjunction with other variables including imaging modality, biopsy site, accompanying core biopsy, tissue type, final diagnosis, and number of smears. Results Of the 632 bone and soft tissue tumor FNA procedures, OSEA was performed in 223 (35.3%) by Cytotechnologists and in 409 (64.7%) by cytopathologists. There was no difference in the adequacy downgrade rate for Cytotechnologists versus cytopathologists during this study period (4.5 versus 2.4%, P = 0.23). The adequacy rates for procedures in which OSEA was performed by Cytotechnologists and cytopathologists did not differ significantly (78.9 versus 84.1%, P = 0.13). Conclusions Cytotechnologists and cytopathologists are comparably accurate in OSEA of bone and soft tissue neoplasms.
-
Cytotechnologist-attended on-site evaluation of adequacy for metastatic disease involving bone and soft tissue.
Acta cytologica, 2013Co-Authors: Matthew T. Olson, Anna Novak, Thiraphon Boonyaarunnate, Hinna Shahid, John Kirby, Syed Z. AliAbstract:Introduction: Image-guided fine needle aspiration (FNA) of the musculoskeletal system is expensive to perform and repeat, so on-site evaluation of adequacy (OSEA) is increasingly used to ensure an optimal sample. Metastatic disease to the musculoskeletal system is not uncommon and often requires OSEA when sampled. At large academic centers, Cytotechnologists have filled the increased demand for OSEA. However, the performance of Cytotechnologists has not been compared with that of cytopathologists for OSEA in FNA of metastatic disease involving bone and soft tissue. Methods: We retrospectively analyzed 10 years of data in which both Cytotechnologists and cytopathologists performed OSEA for 1,995 FNAs of bone and soft tissue sites in which metastatic malignancy was suspected or found. We calculated adequacy and accuracy statistics in conjunction with other variables including imaging modality, biopsy site, accompanying core biopsy, tissue type, final diagnosis, and number of smears. Results: A total of 1,995 aspirates of metastatic disease carcinoma, melanoma or lymphoma to bone or soft tissue had OSEA performed by Cytotechnologists (681, 33.7%) or cytopathologists (1,314, 66.3%). The adequacy downgrade rate was statistically equivalent (4.1 vs. 3.6%; p = 0.64). Conclusion: Cytotechnologists and cytopathologists perform with reasonable equivalence at OSEA of aspirates from metastatic carcinoma, melanoma or lymphoma involving bone or soft tissue.
Thiraphon Boonyaarunnate - One of the best experts on this subject based on the ideXlab platform.
-
Accuracy of Cytotechnologist Evaluation of Specimen Adequacy and Screening Interpretation of Malignancy in Fine-Needle Aspiration of the Liver
Acta cytologica, 2014Co-Authors: Aadil Ahmed, Syed Z. Ali, Anna Novak, Aisha Farhat Sheerin, Thiraphon Boonyaarunnate, Matthew T. OlsonAbstract:Objective: To evaluate the performance of Cytotechnologists in assessing the adequacy and accuracy of the preliminary diagnosis for fine-needle aspirates of the liver. Study Design: We retrospectively analyzed 10 years of data and found 589 cases of ultrasound-guided fine-needle aspiration (FNA) of the liver with on-site evaluation of adequacy (OSEA). All the OSEA were performed by the cytopathologist because OSEA of liver FNA is not performed by Cytotechnologists at our institution at present. After OSEA, the material was seen by Cytotechnologists who rendered an adequacy assessment and preliminary diagnosis. We calculated the adequacy and accuracy statistics and compared the performance of the Cytotechnologists with the OSEA and final interpretation. Results: There was no statistically significant difference in adequacy downgrade rate for Cytotechnologist versus cytopathologist assessment during the study period (5 vs. 3%, p = 0.06). A total agreement of 88% was noted in overall diagnosis with 97% agreement in malignant cases. Conclusion: Cytotechnologists assess the adequacy of liver FNA accurately and there is therefore potential for them to perform OSEA for liver FNA.
-
Cytotechnologist-attended on-site evaluation of adequacy for fine-needle aspiration of bone and soft tissue neoplasms.
Journal of the American Society of Cytopathology, 2013Co-Authors: Matthew T. Olson, Anna Novak, Thiraphon Boonyaarunnate, Hinna Shahid, John Kirby, Syed Z. AliAbstract:Introduction On-site evaluation of adequacy (OSEA) is commonly used to increase the adequacy rate of fine-needle aspiration (FNA) procedures. OSEA is increasingly necessary with the widespread use of image-guided procedures, which are expensive to perform and repeat. The increased demand for OSEA has prompted an increasing reliance on Cytotechnologists for OSEA in many practices, including ours. However, the performance of Cytotechnologists has not been compared with that of cytopathologists for OSEA in FNA of bone and soft tissue tumors. Materials and methods We retrospectively analyzed 10 years of data in which both Cytotechnologists and cytopathologists performed OSEA for 632 bone and soft tissue tumor FNA. We calculated adequacy and accuracy statistics in conjunction with other variables including imaging modality, biopsy site, accompanying core biopsy, tissue type, final diagnosis, and number of smears. Results Of the 632 bone and soft tissue tumor FNA procedures, OSEA was performed in 223 (35.3%) by Cytotechnologists and in 409 (64.7%) by cytopathologists. There was no difference in the adequacy downgrade rate for Cytotechnologists versus cytopathologists during this study period (4.5 versus 2.4%, P = 0.23). The adequacy rates for procedures in which OSEA was performed by Cytotechnologists and cytopathologists did not differ significantly (78.9 versus 84.1%, P = 0.13). Conclusions Cytotechnologists and cytopathologists are comparably accurate in OSEA of bone and soft tissue neoplasms.
-
Cytotechnologist-attended on-site evaluation of adequacy for metastatic disease involving bone and soft tissue.
Acta cytologica, 2013Co-Authors: Matthew T. Olson, Anna Novak, Thiraphon Boonyaarunnate, Hinna Shahid, John Kirby, Syed Z. AliAbstract:Introduction: Image-guided fine needle aspiration (FNA) of the musculoskeletal system is expensive to perform and repeat, so on-site evaluation of adequacy (OSEA) is increasingly used to ensure an optimal sample. Metastatic disease to the musculoskeletal system is not uncommon and often requires OSEA when sampled. At large academic centers, Cytotechnologists have filled the increased demand for OSEA. However, the performance of Cytotechnologists has not been compared with that of cytopathologists for OSEA in FNA of metastatic disease involving bone and soft tissue. Methods: We retrospectively analyzed 10 years of data in which both Cytotechnologists and cytopathologists performed OSEA for 1,995 FNAs of bone and soft tissue sites in which metastatic malignancy was suspected or found. We calculated adequacy and accuracy statistics in conjunction with other variables including imaging modality, biopsy site, accompanying core biopsy, tissue type, final diagnosis, and number of smears. Results: A total of 1,995 aspirates of metastatic disease carcinoma, melanoma or lymphoma to bone or soft tissue had OSEA performed by Cytotechnologists (681, 33.7%) or cytopathologists (1,314, 66.3%). The adequacy downgrade rate was statistically equivalent (4.1 vs. 3.6%; p = 0.64). Conclusion: Cytotechnologists and cytopathologists perform with reasonable equivalence at OSEA of aspirates from metastatic carcinoma, melanoma or lymphoma involving bone or soft tissue.
Christopher J Vandenbussche - One of the best experts on this subject based on the ideXlab platform.
-
Cytotechnologist Performance for Screening Hürthle Cell Atypia in Indeterminate Thyroid Fine-Needle Aspirates.
Acta cytologica, 2015Co-Authors: Christopher J Vandenbussche, Syed Z. Ali, Christina Adams, Matthew T. OlsonAbstract:Objectives: We have previously shown that specimens diagnosed as containing Hurthle cells have a 12% chance of being malignant if they are classified as atypia of undetermined significance (AUS-HC). The identification of Hurthle cells by Cytotechnologists (CTs) during screening can improve cytopathologist efficiency and may prevent diagnostic errors due to the oversights of focal findings. Here, we examine the performance of our institutional CTs when screening for Hurthle cell atypia in thyroid fine-needle aspiration (FNA) specimens. Study Design: Information on 8,814 thyroid cytopathology specimens was retrieved for a 10-year period. Specimens were screened by 1 of 11 CTs. A subsample of cases was categorized either as AUS-HC or suspicious for Hurthle cell neoplasm. Results: AUS-HC screening diagnoses were more likely to be downgraded to benign but less likely to be upgraded compared to AUS diagnoses with nuclear or microfollicular atypia. AUS-HC represents almost all papillary thyroid carcinoma (PTC) screening diagnoses downgraded to the AUS category, which suggests that even low levels of Hurthle cell atypia can result in PTC being included in the differential diagnosis. Conclusion: Overall, there are few major discrepancies between CT and pathologist diagnoses for specimens containing Hurthle cell atypia.
-
Cytotechnologist performance for detecting nuclear atypia in indeterminate thyroid fine needle aspirates
Acta Cytologica, 2014Co-Authors: Christopher J Vandenbussche, Christina Adams, Matthew T. OlsonAbstract:Introduction: The thyroid gland is arguably the fastest growing anatomic site for fine needle aspiration (FNA). With the increase of thyroid cases, a reevaluation
