The Experts below are selected from a list of 31047 Experts worldwide ranked by ideXlab platform
Manojit Pal - One of the best experts on this subject based on the ideXlab platform.
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a new strategy for accessing s 1 furan 2 yl pent 4 en 1 ol a key precursor of ipomoeassin family of compounds and c1 c15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, Yogi B Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
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A new strategy for accessing (S)-1-(furan-2-yl)pent-4-en-1-ol: a key precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, B. Yogi Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
Subba Rao Jammula - One of the best experts on this subject based on the ideXlab platform.
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a new strategy for accessing s 1 furan 2 yl pent 4 en 1 ol a key precursor of ipomoeassin family of compounds and c1 c15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, Yogi B Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
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A new strategy for accessing (S)-1-(furan-2-yl)pent-4-en-1-ol: a key precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, B. Yogi Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
Sudhakar Tatina - One of the best experts on this subject based on the ideXlab platform.
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a new strategy for accessing s 1 furan 2 yl pent 4 en 1 ol a key precursor of ipomoeassin family of compounds and c1 c15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, Yogi B Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
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A new strategy for accessing (S)-1-(furan-2-yl)pent-4-en-1-ol: a key precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, B. Yogi Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
Thalishetti Krishna - One of the best experts on this subject based on the ideXlab platform.
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a new strategy for accessing s 1 furan 2 yl pent 4 en 1 ol a key precursor of ipomoeassin family of compounds and c1 c15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, Yogi B Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
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A new strategy for accessing (S)-1-(furan-2-yl)pent-4-en-1-ol: a key precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, B. Yogi Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
Venkateswara Rao Anna - One of the best experts on this subject based on the ideXlab platform.
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a new strategy for accessing s 1 furan 2 yl pent 4 en 1 ol a key precursor of ipomoeassin family of compounds and c1 c15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, Yogi B Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
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A new strategy for accessing (S)-1-(furan-2-yl)pent-4-en-1-ol: a key precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins
Tetrahedron Letters, 2016Co-Authors: Subba Rao Jammula, Venkateswara Rao Anna, Sudhakar Tatina, Thalishetti Krishna, B. Yogi Sreenivas, Manojit PalAbstract:A highly efficient synthesis of (S)-1-(furan-2-yl)pent-4-en-1-ol, known to be an initial precursor of Ipomoeassin family of compounds and C1–C15 domain of halichondrins has been achieved via a sequence involving the use of Weinreb amide formation followed by Weinreb ketone synthesis and finally CBS (Corey–Bakshi–Shibata) reduction. Detailed study on improvement of each step is described. The title compound was converted to a potential Cytotoxic Agent for further pharmacological studies.
