Decerebration

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Michel Jouvet - One of the best experts on this subject based on the ideXlab platform.

  • effects of Decerebration on blood pressure during paradoxical sleep in cats
    Brain Research Bulletin, 1995
    Co-Authors: Norio Kanamori, Kazuya Sakai, Hiroyoshi Sei, Antoine Bouvard, Denise Salvert, G Vannimercier, Michel Jouvet
    Abstract:

    Abstract We investigated the effects of Decerebration on long-term variations in arterial blood pressure during paradoxical sleep (PS) in cats. In normal cats, the blood pressure decreased during the transition from slow wave sleep to PS and maintained its lower level throughout PS for several days after surgery. After this early postoperative stage, however, the arterial hypotension was replaced by tonic and phasic rises in blood pressure during PS. Such long-term changes in blood pressure were completely abolished when the brain stem was transected at the ponto-mesencepholic junction, and the cats consistently exhibited a sustained fall in blood pressure throughout the survival periods of 1 month or more.

Nicla Romano - One of the best experts on this subject based on the ideXlab platform.

  • Effects of hypophyseal or thymic allograft on thymus development in partially decerebrate chicken embryos: expression of PCNA and CD3 markers
    PAGEPress Publications, 2010
    Co-Authors: M. Aita, F. Benedetti, E. Carafelli, E. Caccia, Nicla Romano
    Abstract:

    Changes in chicken embryo thymus after partial Decerebration (including the hypophysis) and after hypophyseal or thymic allograft were investigated. Chicken embryos were partially decerebrated at 36-40 hr of incubation and on day 12 received a hypophysis or a thymus allograft from 18-day-old donor embryos. The thymuses of normal, sham-operated and partially decerebrate embryos were collected on day 12 and 18. The thymuses of the grafted embryos were collected on day 18. The samples were examined with histological method and tested for the anti-PCNA and anti-CD3 immune-reactions. After partial Decerebration, the thymic cortical and medullary compartments diminished markedly in size. Anti-PCNA and anti-CD3 revealed a reduced immune-reaction, verified also by statistical analysis. In hypophyseal or grafted embryos, the thymic morphological compartments improved, the anti-PCNA and anti-CD3 immune-reactions recovered much better after the thymic graft, probably due to the thymic growth factors and also by an emigration of thymocytes from the same grafted thymus

  • effects of partial Decerebration and hypophyseal allograft in the thymus of chicken embryos thymostimulin localization and enzymatic activities
    European Journal of Histochemistry, 2006
    Co-Authors: M. Aita, Nicla Romano
    Abstract:

    Changes in chicken embryo thymus after partial Decerebration (including the hypophysis) and hypophyseal allograft were investigated. Chicken embryos were partially decerebrated at 36-40 hr of incubation and on day 12 received a hypophyseal allograft from 18-day-old donor embryos. The embryonic thymuses were collected on day 18 and examined with histological methods, tested for the anti-thymostimulin-like immune-reaction, and for histoenzymatic activities and compared with normal and sham-operated embryos at the same age. After partial Decerebration, the thymic cortical and medullary compartments diminished markedly in size. Anti-thymostimulin, succinic dehydrogenase and ATPase enzymatic activities tested, yielded negative reactions. In partially decerebrated hypophyseal allografted embryos, the same thymic compartments improved and anti-thymostimulin-like immune-reaction and enzymatic activities partially recovered. These findings confirmed the key role of hypophysis in thymic ontogenic development and provided new information in metabolic enzymatic pathways and synthesis of a thymostimulin-like substance in the thymus.

Norio Kanamori - One of the best experts on this subject based on the ideXlab platform.

  • effects of Decerebration on blood pressure during paradoxical sleep in cats
    Brain Research Bulletin, 1995
    Co-Authors: Norio Kanamori, Kazuya Sakai, Hiroyoshi Sei, Antoine Bouvard, Denise Salvert, G Vannimercier, Michel Jouvet
    Abstract:

    Abstract We investigated the effects of Decerebration on long-term variations in arterial blood pressure during paradoxical sleep (PS) in cats. In normal cats, the blood pressure decreased during the transition from slow wave sleep to PS and maintained its lower level throughout PS for several days after surgery. After this early postoperative stage, however, the arterial hypotension was replaced by tonic and phasic rises in blood pressure during PS. Such long-term changes in blood pressure were completely abolished when the brain stem was transected at the ponto-mesencepholic junction, and the cats consistently exhibited a sustained fall in blood pressure throughout the survival periods of 1 month or more.

P. Kabai - One of the best experts on this subject based on the ideXlab platform.

  • Methamphetamine-Induced Stereotypies in Newly-Hatched Decerebrated Domestic Chicks
    1999
    Co-Authors: P. Kabai, Andras Liker, Andras Csillag
    Abstract:

    Metamphetamine in high dose has been reported to induce stereotypic behavior of abnormal form in the pigeon and domestic chick. A number of reports suggested that the target of metampheta-mine was the paleostriatal complex, the highest motor center of the avian brain. The present study tested this hypothesis by treating newly-hatched domestic chicks with high dose of metamphet-amine (10 mg/kg b.w.) after complete Decerebration or sham operation. Stereotypic mandibula-tions were observed both in sham-operated and in decerebrated birds in similar form following methamphetamine treatment. The results suggested that brainstem pattern generators remain re-sponsive to dopaminergic stimuli in the absence of the main telencephalic (striatal) targets. KEY WORDS: Domestic chick; methamphetamine; dopamine; basal ganglia; paleostriatum; stereotypic behavior

  • persistence of approach response after Decerebration in newly hatched quail chicks
    Physiology & Behavior, 1993
    Co-Authors: P. Kabai, J. K. Kovach
    Abstract:

    The role of telencephalon in controlling the unconditional approach response was studied in newly hatched Japanese quail chicks by lesions. Approach to flickering light and a moving object were not diminished by ablation of various telencephalic areas, ranging from caudal forebrain lesions to complete bilateral hemispherectomy. Open field activity and tonic immobility were likewise unaffected. Results indicated that the neural mediation of unconditional sensory-motor components of imprinting is anatomically separated from the telencephalon, where recognition memory is thought to be formed.

  • Japanese quail Ch ick Imprinting Approach Following response Open field Tonic
    1992
    Co-Authors: P. Kabai, J. K. Kovach
    Abstract:

    KABAI, P. AND J. K. KOVACH. Persistence of approach response after Decerebration in newly hatched quail chicks. PHYSIOL BEHAV 53(4) 699-707, 1993.--The role of telencephalon in controlling the unconditional pproach response was studied in newly hatched Japanese quail chicks by lesions. Approach to flickering light and a moving object were not diminished by ablation of various telencephalic areas, ranging from caudal forebrain lesions to complete bilateral hemispherectomy. Open field activity and tonic immobility were likewise unaffected. Results indicated that the neural mediation of unconditional sensory-motor components of imprinting isanatomically separated from the telencephalon, where recognition memory is thought to be formed

M. Aita - One of the best experts on this subject based on the ideXlab platform.

  • Effects of hypophyseal or thymic allograft on thymus development in partially decerebrate chicken embryos: expression of PCNA and CD3 markers
    PAGEPress Publications, 2010
    Co-Authors: M. Aita, F. Benedetti, E. Carafelli, E. Caccia, Nicla Romano
    Abstract:

    Changes in chicken embryo thymus after partial Decerebration (including the hypophysis) and after hypophyseal or thymic allograft were investigated. Chicken embryos were partially decerebrated at 36-40 hr of incubation and on day 12 received a hypophysis or a thymus allograft from 18-day-old donor embryos. The thymuses of normal, sham-operated and partially decerebrate embryos were collected on day 12 and 18. The thymuses of the grafted embryos were collected on day 18. The samples were examined with histological method and tested for the anti-PCNA and anti-CD3 immune-reactions. After partial Decerebration, the thymic cortical and medullary compartments diminished markedly in size. Anti-PCNA and anti-CD3 revealed a reduced immune-reaction, verified also by statistical analysis. In hypophyseal or grafted embryos, the thymic morphological compartments improved, the anti-PCNA and anti-CD3 immune-reactions recovered much better after the thymic graft, probably due to the thymic growth factors and also by an emigration of thymocytes from the same grafted thymus

  • effects of partial Decerebration and hypophyseal allograft in the thymus of chicken embryos thymostimulin localization and enzymatic activities
    European Journal of Histochemistry, 2006
    Co-Authors: M. Aita, Nicla Romano
    Abstract:

    Changes in chicken embryo thymus after partial Decerebration (including the hypophysis) and hypophyseal allograft were investigated. Chicken embryos were partially decerebrated at 36-40 hr of incubation and on day 12 received a hypophyseal allograft from 18-day-old donor embryos. The embryonic thymuses were collected on day 18 and examined with histological methods, tested for the anti-thymostimulin-like immune-reaction, and for histoenzymatic activities and compared with normal and sham-operated embryos at the same age. After partial Decerebration, the thymic cortical and medullary compartments diminished markedly in size. Anti-thymostimulin, succinic dehydrogenase and ATPase enzymatic activities tested, yielded negative reactions. In partially decerebrated hypophyseal allografted embryos, the same thymic compartments improved and anti-thymostimulin-like immune-reaction and enzymatic activities partially recovered. These findings confirmed the key role of hypophysis in thymic ontogenic development and provided new information in metabolic enzymatic pathways and synthesis of a thymostimulin-like substance in the thymus.