The Experts below are selected from a list of 58416 Experts worldwide ranked by ideXlab platform
Zhen Zhang - One of the best experts on this subject based on the ideXlab platform.
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Voltammetric sensing of recombinant viral Dengue Virus 2 NS1 based on Au nanoparticle–decorated multiwalled carbon nanotube composites
Microchimica Acta, 2020Co-Authors: Quentin Palomar, Chantal Gondran, Michael Holzinger, Serge Cosnier, Zhen ZhangAbstract:A homemade gold electrode is modified with a carbon nanotubes/gold nanoparticles nanocomposite to perform selective and sensitive electrochemical detection of Dengue toxin. This nanostructured composite offers a large specific surface and a reactive interface allowing the immobilization of biological material. Dengue antibodies are immobilized on gold nanoparticles via covalent bonding for Dengue toxin detection. The porous tridimensional network of carbon nanotubes and gold nanoparticles enhances the electrochemical signal and the overall performance of the sensor. After optimization, the system exhibits a high sensitivity of − 0.44 ± 0.01 μA per decade with wide linear range between 1 × 10 −12 and 1 × 10 −6 g/mL at a working potential of 0.22 V vs Ag/AgCl. The extremely low detection limit (3 × 10 −13 g/mL) ranks this immunosensor as one of the most efficient reported in the literature for the detection of recombinant viral Dengue Virus 2 NS1. This biosensor also offers good selectivity, characterized by a low response to various non-specific targets and assays in human serum. The outstanding performances and the reproducibility of the system place the biosensor developed among the best candidates for future medical applications and for early diagnosis of Dengue fever.
Quentin Palomar - One of the best experts on this subject based on the ideXlab platform.
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Voltammetric sensing of recombinant viral Dengue Virus 2 NS1 based on Au nanoparticle–decorated multiwalled carbon nanotube composites
Microchimica Acta, 2020Co-Authors: Quentin Palomar, Chantal Gondran, Michael Holzinger, Serge Cosnier, Zhen ZhangAbstract:A homemade gold electrode is modified with a carbon nanotubes/gold nanoparticles nanocomposite to perform selective and sensitive electrochemical detection of Dengue toxin. This nanostructured composite offers a large specific surface and a reactive interface allowing the immobilization of biological material. Dengue antibodies are immobilized on gold nanoparticles via covalent bonding for Dengue toxin detection. The porous tridimensional network of carbon nanotubes and gold nanoparticles enhances the electrochemical signal and the overall performance of the sensor. After optimization, the system exhibits a high sensitivity of − 0.44 ± 0.01 μA per decade with wide linear range between 1 × 10 −12 and 1 × 10 −6 g/mL at a working potential of 0.22 V vs Ag/AgCl. The extremely low detection limit (3 × 10 −13 g/mL) ranks this immunosensor as one of the most efficient reported in the literature for the detection of recombinant viral Dengue Virus 2 NS1. This biosensor also offers good selectivity, characterized by a low response to various non-specific targets and assays in human serum. The outstanding performances and the reproducibility of the system place the biosensor developed among the best candidates for future medical applications and for early diagnosis of Dengue fever.
Chantal Gondran - One of the best experts on this subject based on the ideXlab platform.
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Voltammetric sensing of recombinant viral Dengue Virus 2 NS1 based on Au nanoparticle–decorated multiwalled carbon nanotube composites
Microchimica Acta, 2020Co-Authors: Quentin Palomar, Chantal Gondran, Michael Holzinger, Serge Cosnier, Zhen ZhangAbstract:A homemade gold electrode is modified with a carbon nanotubes/gold nanoparticles nanocomposite to perform selective and sensitive electrochemical detection of Dengue toxin. This nanostructured composite offers a large specific surface and a reactive interface allowing the immobilization of biological material. Dengue antibodies are immobilized on gold nanoparticles via covalent bonding for Dengue toxin detection. The porous tridimensional network of carbon nanotubes and gold nanoparticles enhances the electrochemical signal and the overall performance of the sensor. After optimization, the system exhibits a high sensitivity of − 0.44 ± 0.01 μA per decade with wide linear range between 1 × 10 −12 and 1 × 10 −6 g/mL at a working potential of 0.22 V vs Ag/AgCl. The extremely low detection limit (3 × 10 −13 g/mL) ranks this immunosensor as one of the most efficient reported in the literature for the detection of recombinant viral Dengue Virus 2 NS1. This biosensor also offers good selectivity, characterized by a low response to various non-specific targets and assays in human serum. The outstanding performances and the reproducibility of the system place the biosensor developed among the best candidates for future medical applications and for early diagnosis of Dengue fever.
Michael Holzinger - One of the best experts on this subject based on the ideXlab platform.
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Voltammetric sensing of recombinant viral Dengue Virus 2 NS1 based on Au nanoparticle–decorated multiwalled carbon nanotube composites
Microchimica Acta, 2020Co-Authors: Quentin Palomar, Chantal Gondran, Michael Holzinger, Serge Cosnier, Zhen ZhangAbstract:A homemade gold electrode is modified with a carbon nanotubes/gold nanoparticles nanocomposite to perform selective and sensitive electrochemical detection of Dengue toxin. This nanostructured composite offers a large specific surface and a reactive interface allowing the immobilization of biological material. Dengue antibodies are immobilized on gold nanoparticles via covalent bonding for Dengue toxin detection. The porous tridimensional network of carbon nanotubes and gold nanoparticles enhances the electrochemical signal and the overall performance of the sensor. After optimization, the system exhibits a high sensitivity of − 0.44 ± 0.01 μA per decade with wide linear range between 1 × 10 −12 and 1 × 10 −6 g/mL at a working potential of 0.22 V vs Ag/AgCl. The extremely low detection limit (3 × 10 −13 g/mL) ranks this immunosensor as one of the most efficient reported in the literature for the detection of recombinant viral Dengue Virus 2 NS1. This biosensor also offers good selectivity, characterized by a low response to various non-specific targets and assays in human serum. The outstanding performances and the reproducibility of the system place the biosensor developed among the best candidates for future medical applications and for early diagnosis of Dengue fever.
Serge Cosnier - One of the best experts on this subject based on the ideXlab platform.
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Voltammetric sensing of recombinant viral Dengue Virus 2 NS1 based on Au nanoparticle–decorated multiwalled carbon nanotube composites
Microchimica Acta, 2020Co-Authors: Quentin Palomar, Chantal Gondran, Michael Holzinger, Serge Cosnier, Zhen ZhangAbstract:A homemade gold electrode is modified with a carbon nanotubes/gold nanoparticles nanocomposite to perform selective and sensitive electrochemical detection of Dengue toxin. This nanostructured composite offers a large specific surface and a reactive interface allowing the immobilization of biological material. Dengue antibodies are immobilized on gold nanoparticles via covalent bonding for Dengue toxin detection. The porous tridimensional network of carbon nanotubes and gold nanoparticles enhances the electrochemical signal and the overall performance of the sensor. After optimization, the system exhibits a high sensitivity of − 0.44 ± 0.01 μA per decade with wide linear range between 1 × 10 −12 and 1 × 10 −6 g/mL at a working potential of 0.22 V vs Ag/AgCl. The extremely low detection limit (3 × 10 −13 g/mL) ranks this immunosensor as one of the most efficient reported in the literature for the detection of recombinant viral Dengue Virus 2 NS1. This biosensor also offers good selectivity, characterized by a low response to various non-specific targets and assays in human serum. The outstanding performances and the reproducibility of the system place the biosensor developed among the best candidates for future medical applications and for early diagnosis of Dengue fever.