The Experts below are selected from a list of 900 Experts worldwide ranked by ideXlab platform
Shigeyuki Ebisu - One of the best experts on this subject based on the ideXlab platform.
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ammonium hexafluorosilicate elicits calcium phosphate precipitation and shows continuous Dentin Tubule occlusion
Dental Materials, 2008Co-Authors: Toshiyuki Suge, A. Kawasaki, Kunio Ishikawa, Takashi Matsuo, Shigeyuki EbisuAbstract:Abstract Diamine silver fluoride [AgF: (NH 3 ) 2 AgF] has been used clinically in Japan, as it reduces dental caries and Dentin hypersensitivity. However, AgF stains the teeth black due to silver precipitation. To overcome this drawback, the authors prepared ammonium hexafluorosilicate [SiF: (NH 4 ) 2 SiF 6 ], which does not stain the teeth, and SiF occluded open Dentin Tubules completely with silica–calcium phosphate precipitate. Objectives The aim of this study was to evaluate the duration of Dentin Tubule occlusion after SiF treatment in a simulated oral environment. Methods To simulate Dentin Tubules subject to Dentin hypersensitivity, Dentin disks were treated with EDTA for 2 min. The disks were treated with 0.476 mol/L SiF for 3 min, and then the disks were immersed in synthetic saliva, which was regularly replenished to maintain its ionic concentration, for up to 7 days. The occluding ability of the Dentin Tubules was evaluated using scanning electron microscopy (SEM), and the hydraulic conductance was measured following Pashley's method at regular intervals. Results SEM photographs demonstrated that Dentin Tubules were occluded homogeneously and completely with the precipitate at 7 days after treatment with SiF. In addition, newly formed calcium phosphate precipitate was present at the Dentin surface. The Dentin permeability showed a consistently low value throughout the experimental period. The values immediately after SiF treatment and 7 days after immersion were 11.9 ± 3.7% and 7.9 ± 2.9%, respectively. Significance Ammonium hexafluorosilicate is useful for the treatment of Dentin hypersensitivity, since ammonium hexafluorosilicate induced calcium phosphate precipitation from the saliva; therefore, it has a continuous effect on Dentin Tubules occlusion under a simulated oral environment.
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Effect of ammonium hexafluorosilicate on Dentin Tubule occlusion for the treatment of Dentin hypersensitivity.
American journal of dentistry, 2006Co-Authors: Toshiyuki Suge, A. Kawasaki, Kunio Ishikawa, Takashi Matsuo, Shigeyuki EbisuAbstract:PURPOSE To evaluate the occluding ability of ammonium hexafluorosilicate (SiF). METHODS Dentin disks prepared from human extracted teeth were grouped as follows to prepare different situations of Dentin hypersensitivity: (1) those sonicated for 20 minutes; (2) those treated with 0.5 mol/L EDTA for 2 minutes; (3) those treated with 6% citric acid for 2 minutes; (4) those treated with 50% citric acid for 2 minutes. Then, SiF or diamine silver fluoride (AgF) was applied to the Dentin disks and the Dentin Tubule occlusion was observed with scanning electron microscopy (SEM). The percent of open Tubules before and after SiF or AgF treatment were measured by NIH image using SEM photographs. Also, the Dentin permeability was measured. RESULTS SEM micrographs demonstrated that the Dentin Tubules were completely occluded by the precipitate after SiF treatment. Also, the Dentin permeability was reduced to 10.3%. In contrast, most of the Dentin Tubules remained open after AgF treatment. EDXA analysis showed that the precipitate in the Dentin Tubules that forms after SiF treatment contains Si, Ca and P, indicating a silica-calcium phosphate complex.
C F Cox - One of the best experts on this subject based on the ideXlab platform.
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a comparative scanning electron microscopic study on the characteristics of demineralized Dentin root surface using different tetracycline hcl concentrations and application times
Journal of Periodontology, 2000Co-Authors: Gulden A Isik, Berna Tarim, Abeer A Hafez, Funda Yalcin, Utku Onan, C F CoxAbstract:Background: The use of demineralizing agents has been reported to enhance the degree of connective tissue attachment to denuded roots. Of the agents used, tetracycline HCl has received the most attention. Methods: The purpose of this study was to evaluate and compare the SEM surface morphology of human root Dentin following various concentrations and application times of tetracycline HCl. The surface characteristics were compared and the width of Dentin Tubule orifices were measured and analyzed. Twelve human teeth were collected and stored in distilled water after soft tissue removal using hand instruments. The apical third of each root was removed and remaining mid-root region was sectioned longitudinally through the root canal following removal of its cementum with a fine diamond bur. A total of 48 Dentin specimens were randomly divided into 8 groups for conditioning at different tetracycline HCl concentrations, at 0, 10, 25, 50, 75, 100, 125, and 150 mg/ml. Application times for each group were 1, 3, ...
Toshiyuki Suge - One of the best experts on this subject based on the ideXlab platform.
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ammonium hexafluorosilicate elicits calcium phosphate precipitation and shows continuous Dentin Tubule occlusion
Dental Materials, 2008Co-Authors: Toshiyuki Suge, A. Kawasaki, Kunio Ishikawa, Takashi Matsuo, Shigeyuki EbisuAbstract:Abstract Diamine silver fluoride [AgF: (NH 3 ) 2 AgF] has been used clinically in Japan, as it reduces dental caries and Dentin hypersensitivity. However, AgF stains the teeth black due to silver precipitation. To overcome this drawback, the authors prepared ammonium hexafluorosilicate [SiF: (NH 4 ) 2 SiF 6 ], which does not stain the teeth, and SiF occluded open Dentin Tubules completely with silica–calcium phosphate precipitate. Objectives The aim of this study was to evaluate the duration of Dentin Tubule occlusion after SiF treatment in a simulated oral environment. Methods To simulate Dentin Tubules subject to Dentin hypersensitivity, Dentin disks were treated with EDTA for 2 min. The disks were treated with 0.476 mol/L SiF for 3 min, and then the disks were immersed in synthetic saliva, which was regularly replenished to maintain its ionic concentration, for up to 7 days. The occluding ability of the Dentin Tubules was evaluated using scanning electron microscopy (SEM), and the hydraulic conductance was measured following Pashley's method at regular intervals. Results SEM photographs demonstrated that Dentin Tubules were occluded homogeneously and completely with the precipitate at 7 days after treatment with SiF. In addition, newly formed calcium phosphate precipitate was present at the Dentin surface. The Dentin permeability showed a consistently low value throughout the experimental period. The values immediately after SiF treatment and 7 days after immersion were 11.9 ± 3.7% and 7.9 ± 2.9%, respectively. Significance Ammonium hexafluorosilicate is useful for the treatment of Dentin hypersensitivity, since ammonium hexafluorosilicate induced calcium phosphate precipitation from the saliva; therefore, it has a continuous effect on Dentin Tubules occlusion under a simulated oral environment.
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Effect of ammonium hexafluorosilicate on Dentin Tubule occlusion for the treatment of Dentin hypersensitivity.
American journal of dentistry, 2006Co-Authors: Toshiyuki Suge, A. Kawasaki, Kunio Ishikawa, Takashi Matsuo, Shigeyuki EbisuAbstract:PURPOSE To evaluate the occluding ability of ammonium hexafluorosilicate (SiF). METHODS Dentin disks prepared from human extracted teeth were grouped as follows to prepare different situations of Dentin hypersensitivity: (1) those sonicated for 20 minutes; (2) those treated with 0.5 mol/L EDTA for 2 minutes; (3) those treated with 6% citric acid for 2 minutes; (4) those treated with 50% citric acid for 2 minutes. Then, SiF or diamine silver fluoride (AgF) was applied to the Dentin disks and the Dentin Tubule occlusion was observed with scanning electron microscopy (SEM). The percent of open Tubules before and after SiF or AgF treatment were measured by NIH image using SEM photographs. Also, the Dentin permeability was measured. RESULTS SEM micrographs demonstrated that the Dentin Tubules were completely occluded by the precipitate after SiF treatment. Also, the Dentin permeability was reduced to 10.3%. In contrast, most of the Dentin Tubules remained open after AgF treatment. EDXA analysis showed that the precipitate in the Dentin Tubules that forms after SiF treatment contains Si, Ca and P, indicating a silica-calcium phosphate complex.
Steven D Hokett - One of the best experts on this subject based on the ideXlab platform.
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the effects of different tetracyclines on the Dentin root surface of instrumented periodontally involved human teeth a comparative scanning electron microscope study
Journal of Periodontology, 1997Co-Authors: James G Madison, Steven D HokettAbstract:This in vitro study compares, by scanning electron microscope (SEM) examination, the surface effects of various topical applications of tetracycline on the instrumented Dentin root surface of human teeth. Eighty-two (82) Dentin samples were prepared from periodontally-compromised teeth planned for extraction. Solutions of tetracycline HCl, doxycycline, minocycline, sumycin, and a saline control were prepared and applied to the Dentin samples for 0.5, 1, 3, 5, and 10 minutes. Each solution pH was measured: tetracycline HCI (pH 1.6), doxycycline (pH 2.2), minocycline (pH 3.8), sumycin (pH 4.4), and saline (pH 5.1). A tetracycline periodontal fiber was also evaluated at 1, 4, 7, and 10 days of exposure for Dentin surface effects. Tetracycline HCI removed the Dentin smear layer leaving clean and open Tubules significantly better than other solutions tested in as little as 30 seconds. Doxycycline and minocycline produced similar results to each other, which were significantly better than sumycin and saline, but not as effective as tetracycline HCl. Smear layer removal was attained by doxycycline and minocycline in five to ten minutes; however, sumycin and the saline control ineffectively removed the surface smear layer and Dentinal Tubules remained partially to totally occluded by debris. The periodontal fiber did not significantly alter the surface smear layer. Results of this study suggest that tetracycline HCl is the best current tetracycline form for root surface conditioning as measured by its ability to affect both Dentin smear layer removal and Dentin Tubule exposure.
T E Van Dyke - One of the best experts on this subject based on the ideXlab platform.
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an in vivo study of Dentin sensitivity the relation of Dentin sensitivity and the patency of Dentin Tubules
Journal of Periodontology, 1991Co-Authors: M F Cuenin, David H. Pashley, M J Scheidt, R B Oneal, S L Strong, J A Horner, T E Van DykeAbstract:Dentin hypersensitivity can be a major problem for periodontal patients. The relationship between Dentin hypersensitivity and the patency of Dentin Tubules in vivo has been established. Thirteen adult patients with teeth scheduled for extraction were selected and a stent fabricated to confirm location of the root surface being examined. Response to a constant air blast was recorded on a numeric pain rating scale (from 0 to 4) during the course of treatment. The tooth surface was initially treated with 0.5 molar EDTA (pH = 7.4), to remove the smear layer and expose Tubules. The region was then treated with either a 3% monopotassium-monohydrogen oxalate solution or a 3% sodium chloride solution, both at pH = 2.4. Solutions were prepared to be indistinguishable to the examiner. Response to air was evaluated before and after EDTA treatment and after treatment with a desensitizing agent. The patient was anesthetized and the treated tooth extracted. Specimens were sectioned, critical point dried, sputter coated with gold, and examined under the scanning electron microscope. Photomicrographs were analyzed by computer assisted digital analysis to evaluate the degree of Tubule occlusion. Statistical analysis by repeated measures ANOVA for univariate tests of hypothesis for within subject effects showed the sodium chloride solution was more effective in reducing Dentin sensitivity than the potassium oxalate solution. Scanning electron micrographic analysis revealed a mean Dentin Tubule aperture size of 1.720 square microns following EDTA treatment alone, 0.564 square micron following potassium oxalate treatment, and 0.386 square micron following sodium chloride treatment.(ABSTRACT TRUNCATED AT 250 WORDS)