The Experts below are selected from a list of 34065 Experts worldwide ranked by ideXlab platform
Akihiro Umezawa - One of the best experts on this subject based on the ideXlab platform.
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single Cell Derived mesenchymal Stem Cells overexpressing csx nkx2 5 and gata4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2007Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.
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Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2006Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.
Yoji Yamada - One of the best experts on this subject based on the ideXlab platform.
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single Cell Derived mesenchymal Stem Cells overexpressing csx nkx2 5 and gata4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2007Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.
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Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2006Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.
Yukiji Takeda - One of the best experts on this subject based on the ideXlab platform.
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single Cell Derived mesenchymal Stem Cells overexpressing csx nkx2 5 and gata4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2007Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.
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Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2006Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.
Kazuhiro Sakurada - One of the best experts on this subject based on the ideXlab platform.
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single Cell Derived mesenchymal Stem Cells overexpressing csx nkx2 5 and gata4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2007Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.
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Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2006Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.
Satoshi Gojo - One of the best experts on this subject based on the ideXlab platform.
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single Cell Derived mesenchymal Stem Cells overexpressing csx nkx2 5 and gata4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2007Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.
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Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 undergo the stochastic cardiomyogenic fate and behave like transient amplifying Cells
Experimental Cell Research, 2006Co-Authors: Yoji Yamada, Kazuhiro Sakurada, Yukiji Takeda, Satoshi Gojo, Akihiro UmezawaAbstract:Bone marrow-Derived stromal Cells can give rise to cardiomyocytes as well as adipocytes, osteocytes, and chondrocytes in vitro. The existence of mesenchymal Stem Cells has been proposed, but it remains unclear if a single-Cell-Derived Stem Cell stochastically commits toward a cardiac lineage. By single-Cell marking, we performed a follow-up study of individual Cells during the differentiation of 9-15c mesenchymal stromal Cells Derived from bone marrow Cells. Three types of Cells, i.e., cardiac myoblasts, cardiac progenitors and multipotent Stem Cells were differentiated from a single Cell, implying that cardiomyocytes are generated stochastically from a single-Cell-Derived Stem Cell. We also demonstrated that overexpression of Csx/Nkx2.5 and GATA4, precardiac mesodermal transcription factors, enhanced cardiomyogenic differentiation of 9-15c Cells, and the frequency of cardiomyogenic differentiation was increased by co-culturing with fetal cardiomyocytes. Single-Cell-Derived mesenchymal Stem Cells overexpressing Csx/Nkx2.5 and GATA4 behaved like cardiac transient amplifying Cells, and still retained their plasticity in vivo.