The Experts below are selected from a list of 300 Experts worldwide ranked by ideXlab platform
Allison R. Phillips - One of the best experts on this subject based on the ideXlab platform.
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Integrating PCR Theory and Bioinformatics into a Research-oriented Primer Design Exercise
CBE life sciences education, 2008Co-Authors: Amber L. Robertson, Allison R. PhillipsAbstract:Polymerase chain reaction (PCR) is a conceptually difficult technique that embodies many fundamental biological processes. Traditionally, students have struggled to analyze PCR results due to an incomplete understanding of the biological concepts (theory) of DNA replication and strand complementarity. Here we describe the Design of a novel research-oriented Exercise that prepares students to Design DNA primers for PCR. Our Exercise Design includes broad and specific learning goals and assessments of student performance and perceptions. We developed this interactive Primer Design Exercise using the principles of scientific teaching to enhance student understanding of the theory behind PCR and provide practice in Designing PCR primers to amplify DNA. In the end, the students were more poised to troubleshoot problems that arose in real experiments using PCR. In addition, students had the opportunity to utilize several bioinformatics tools to gain an increased understanding of primer quality, directionality, and specificity. In the course of this study many misconceptions about DNA replication during PCR and the need for primer specificity were identified and addressed. Students were receptive to the new materials and the majority achieved the learning goals.
C. Wright - One of the best experts on this subject based on the ideXlab platform.
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An Undergraduate Design Exercise at Rolls-Royce Plc
The International journal of mechanical engineering education, 2008Co-Authors: Gary D Lock, C. WrightAbstract:The Department of Mechanical Engineering at the University of Bath has been conducting an undergraduate engine-related Design Exercise at Rolls-Royce, Bristol, since 2000. Each year, between February and September, a team of six undergraduates completes an engine-related Design project under supervision from the company. This work is co-ordinated and assessed at both the company and university, and counts overall as 20% of the student's four-year degree. In addition to working at Rolls-Royce, the students submit reports and give seminars at the university. The Design Exercise is predominantly technical in nature but must include a significant business element. The students are paid as company employees, typically £7200 for the six months. This paper describes the Design Exercise and how it is accommodated within the undergraduate programme of study at the university. The benefits to the university, the students and the company are discussed. In addition, the six students undertaking the 2005 Exercise desc...
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An Undergraduate Industrial Design Exercise at Rolls-Royce plc
Volume 1: Combustion and Fuels Education, 2006Co-Authors: Gary D Lock, V. Cheng, W. Mezzullo, S. Peet, Michael Child, R. Johnson, Colin Pattinson, C. WrightAbstract:The Department of Mechanical Engineering at the University of Bath has been conducting an undergraduate engine-related Design Exercise at Rolls-Royce, Bristol since 2000. Each year a team of six undergraduates complete an engine-related Design project under supervision from the company between February and September. This work is coordinated and assessed at both the company and university, and counts overall as 20% of the student’s four-year degree. In addition to working at Rolls-Royce, the students submit reports and give seminars at the university. The Design Exercise is predominantly technical in nature but must include a significant business element. The students are paid as company employees, typically £7.2k for the six months. This paper describes the Design Exercise and how it is accommodated into the undergraduate programme of study at the University of Bath. The benefits to the university, the students and the company are discussed. In addition, the six students undertaking the 2005 Exercise describe their projects. This year there were three projects, two of which were continuations from previous Design Exercises. The three projects are listed below. Aero-Engine Rotor-Dynamics (V Cheng and S Peet): An experimental and computation study of engine vibration using a rotor-dynamics rig, simulating the engine. The aim was to assess the accuracy and improve the modeling techniques used at Rolls-Royce. Implementing Design for Environment on Gas turbine engines using a Design Tool (W Mezzulo): A study to create a tool to enable the Designer to evaluate the environmental aspects of the life of an engine component. Aero-thermodynamics of aero-engines (M Child, R Johnson and C Pattinson): Various Design aspects of aero-engines, both computational and business. Note that M Child’s project is not discussed here for reasons of Rolls-Royce proprietary and confidentiality.Copyright © 2006 by ASME
Amber L. Robertson - One of the best experts on this subject based on the ideXlab platform.
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Integrating PCR Theory and Bioinformatics into a Research-oriented Primer Design Exercise
CBE life sciences education, 2008Co-Authors: Amber L. Robertson, Allison R. PhillipsAbstract:Polymerase chain reaction (PCR) is a conceptually difficult technique that embodies many fundamental biological processes. Traditionally, students have struggled to analyze PCR results due to an incomplete understanding of the biological concepts (theory) of DNA replication and strand complementarity. Here we describe the Design of a novel research-oriented Exercise that prepares students to Design DNA primers for PCR. Our Exercise Design includes broad and specific learning goals and assessments of student performance and perceptions. We developed this interactive Primer Design Exercise using the principles of scientific teaching to enhance student understanding of the theory behind PCR and provide practice in Designing PCR primers to amplify DNA. In the end, the students were more poised to troubleshoot problems that arose in real experiments using PCR. In addition, students had the opportunity to utilize several bioinformatics tools to gain an increased understanding of primer quality, directionality, and specificity. In the course of this study many misconceptions about DNA replication during PCR and the need for primer specificity were identified and addressed. Students were receptive to the new materials and the majority achieved the learning goals.
Gary D Lock - One of the best experts on this subject based on the ideXlab platform.
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An Undergraduate Design Exercise at Rolls-Royce Plc
The International journal of mechanical engineering education, 2008Co-Authors: Gary D Lock, C. WrightAbstract:The Department of Mechanical Engineering at the University of Bath has been conducting an undergraduate engine-related Design Exercise at Rolls-Royce, Bristol, since 2000. Each year, between February and September, a team of six undergraduates completes an engine-related Design project under supervision from the company. This work is co-ordinated and assessed at both the company and university, and counts overall as 20% of the student's four-year degree. In addition to working at Rolls-Royce, the students submit reports and give seminars at the university. The Design Exercise is predominantly technical in nature but must include a significant business element. The students are paid as company employees, typically £7200 for the six months. This paper describes the Design Exercise and how it is accommodated within the undergraduate programme of study at the university. The benefits to the university, the students and the company are discussed. In addition, the six students undertaking the 2005 Exercise desc...
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An Undergraduate Industrial Design Exercise at Rolls-Royce plc
Volume 1: Combustion and Fuels Education, 2006Co-Authors: Gary D Lock, V. Cheng, W. Mezzullo, S. Peet, Michael Child, R. Johnson, Colin Pattinson, C. WrightAbstract:The Department of Mechanical Engineering at the University of Bath has been conducting an undergraduate engine-related Design Exercise at Rolls-Royce, Bristol since 2000. Each year a team of six undergraduates complete an engine-related Design project under supervision from the company between February and September. This work is coordinated and assessed at both the company and university, and counts overall as 20% of the student’s four-year degree. In addition to working at Rolls-Royce, the students submit reports and give seminars at the university. The Design Exercise is predominantly technical in nature but must include a significant business element. The students are paid as company employees, typically £7.2k for the six months. This paper describes the Design Exercise and how it is accommodated into the undergraduate programme of study at the University of Bath. The benefits to the university, the students and the company are discussed. In addition, the six students undertaking the 2005 Exercise describe their projects. This year there were three projects, two of which were continuations from previous Design Exercises. The three projects are listed below. Aero-Engine Rotor-Dynamics (V Cheng and S Peet): An experimental and computation study of engine vibration using a rotor-dynamics rig, simulating the engine. The aim was to assess the accuracy and improve the modeling techniques used at Rolls-Royce. Implementing Design for Environment on Gas turbine engines using a Design Tool (W Mezzulo): A study to create a tool to enable the Designer to evaluate the environmental aspects of the life of an engine component. Aero-thermodynamics of aero-engines (M Child, R Johnson and C Pattinson): Various Design aspects of aero-engines, both computational and business. Note that M Child’s project is not discussed here for reasons of Rolls-Royce proprietary and confidentiality.Copyright © 2006 by ASME
Matthew A. Swabey - One of the best experts on this subject based on the ideXlab platform.
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Innovative Teaching of IC Design and Manufacture Using the Superchip Platform
IEEE Transactions on Education, 2010Co-Authors: Peter R. Wilson, Iain Mcnally, Reuben Wilcock, Matthew A. SwabeyAbstract:This paper describes how an intelligent chip architecture has allowed a large cohort of undergraduate (UG) students to be given effective practical insight into integrated circuit (IC) Design by Designing and manufacturing their own ICs. To achieve this, an efficient chip architecture, the ?Superchip,? was developed, which allows multiple student Designs to be fabricated on a single IC, and encapsulated in a standard package without excessive cost in terms of time or resources. This paper demonstrates how the practical process has been tightly coupled with theoretical aspects of the degree course and how transferable skills are incorporated into the Design Exercise. Furthermore, the students are introduced at an early stage to the key concepts of teamwork, exposure to real deadlines, and collaborative report writing. This paper provides details of the teaching rationale, Design Exercise overview, Design process, chip architecture, and test regime.
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IC Design and Manufacture for Undergraduates: Theory, Design and Practice
2008Co-Authors: Peter R. Wilson, Iain Mcnally, Matthew A. Swabey, Bashir M. Al-hashimiAbstract:In this paper we describe how the practical Design and manufacture of modern CMOS integrated circuits (ICs) have been incorporated into the second year of our undergraduate Electronics degree program. While many undergraduate degree programs offer theoretical and Design of ICs, none have published a complete Design cycle teaching approach including practical manufacture and test of ICs. We demonstrate how the Design process has been tightly coupled with theoretical aspects of the degree course and incorporate transferable skills into the Design Exercise. We will also provide the technical information on how this Design Exercise can be accomplished sensibly for a large cohort of students (~100) in practical terms.
