The Experts below are selected from a list of 141 Experts worldwide ranked by ideXlab platform

Ji-ho Yoon - One of the best experts on this subject based on the ideXlab platform.

Moonkyoon Chun - One of the best experts on this subject based on the ideXlab platform.

Burnaby Munson - One of the best experts on this subject based on the ideXlab platform.

  • The use of Deuterium Oxide as a mobile phase for structural elucidation by HPLC/UV/ESI/MS
    Analytical Chemistry, 2000
    Co-Authors: Mark A Olsen, Paul G Cummings, Brian M Wagner, Gordon R Nicol, Sonya Kennedy-gabb, Burnaby Munson
    Abstract:

    The use of Deuterium Oxide as a mobile phase in the routine analysis of pharmaceutical compounds was investigated. The Deuterium exchange of labile hydrogen atoms aids in structural confirmation and elucidation of unknown impurities and degradation products. Although Deuterium Oxide as a mobile phase does in some cases change the retention times, the changes in retention times do not interfere with the analysis. A study of the high-performance liquid chromatography system shows that equilibration times for the Deuterium-containing mobile phases are similar to equilibration times with changes of other mobile phases. The use of this technique in the analysis of pharmaceutical compounds and other small molecules is presented.

  • the use of Deuterium Oxide as a mobile phase for structural elucidation by hplc uv esi ms
    Analytical Chemistry, 2000
    Co-Authors: Mark A Olsen, Paul G Cummings, Sonya Kennedygabb, Brian M Wagner, Gordon R Nicol, Burnaby Munson
    Abstract:

    The use of Deuterium Oxide as a mobile phase in the routine analysis of pharmaceutical compounds was investigated. The Deuterium exchange of labile hydrogen atoms aids in structural confirmation and elucidation of unknown impurities and degradation products. Although Deuterium Oxide as a mobile phase does in some cases change the retention times, the changes in retention times do not interfere with the analysis. A study of the high-performance liquid chromatography system shows that equilibration times for the Deuterium-containing mobile phases are similar to equilibration times with changes of other mobile phases. The use of this technique in the analysis of pharmaceutical compounds and other small molecules is presented.

Mark A Olsen - One of the best experts on this subject based on the ideXlab platform.

  • The use of Deuterium Oxide as a mobile phase for structural elucidation by HPLC/UV/ESI/MS
    Analytical Chemistry, 2000
    Co-Authors: Mark A Olsen, Paul G Cummings, Brian M Wagner, Gordon R Nicol, Sonya Kennedy-gabb, Burnaby Munson
    Abstract:

    The use of Deuterium Oxide as a mobile phase in the routine analysis of pharmaceutical compounds was investigated. The Deuterium exchange of labile hydrogen atoms aids in structural confirmation and elucidation of unknown impurities and degradation products. Although Deuterium Oxide as a mobile phase does in some cases change the retention times, the changes in retention times do not interfere with the analysis. A study of the high-performance liquid chromatography system shows that equilibration times for the Deuterium-containing mobile phases are similar to equilibration times with changes of other mobile phases. The use of this technique in the analysis of pharmaceutical compounds and other small molecules is presented.

  • the use of Deuterium Oxide as a mobile phase for structural elucidation by hplc uv esi ms
    Analytical Chemistry, 2000
    Co-Authors: Mark A Olsen, Paul G Cummings, Sonya Kennedygabb, Brian M Wagner, Gordon R Nicol, Burnaby Munson
    Abstract:

    The use of Deuterium Oxide as a mobile phase in the routine analysis of pharmaceutical compounds was investigated. The Deuterium exchange of labile hydrogen atoms aids in structural confirmation and elucidation of unknown impurities and degradation products. Although Deuterium Oxide as a mobile phase does in some cases change the retention times, the changes in retention times do not interfere with the analysis. A study of the high-performance liquid chromatography system shows that equilibration times for the Deuterium-containing mobile phases are similar to equilibration times with changes of other mobile phases. The use of this technique in the analysis of pharmaceutical compounds and other small molecules is presented.

Kathrin Spendier - One of the best experts on this subject based on the ideXlab platform.