The Experts below are selected from a list of 16404 Experts worldwide ranked by ideXlab platform

Anders Kallner - One of the best experts on this subject based on the ideXlab platform.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Introduction Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer. The iCa concentrations of systemic and post filter samples were measured using six distinct, frequently used blood gas analyzers. We obtained iCa results of 74 systemic and 84 post filter samples from patients undergoing RCA for CRRT at the University Medicine of Greifswald. The systemic samples showed concordant results on all analyzers with median iCa concentrations ranging from 1.07 to 1.16 mmol/L. The medians of iCa concentrations for post filter samples ranged from 0.21 to 0.50 mmol/L. Results of >70 % of the post filter samples would lead to major differences in decisions regarding citrate flow depending on the instrument used. Measurements of iCa in post filter samples may give misleading information in monitoring the RCA. Recommendations of the dialysis Manufacturer need to be revised. Meanwhile, little weight should be given to post filter iCa. Reference methods for low iCa in whole blood containing citrate should be established.

Patrik Schwarzer - One of the best experts on this subject based on the ideXlab platform.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Introduction Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer. The iCa concentrations of systemic and post filter samples were measured using six distinct, frequently used blood gas analyzers. We obtained iCa results of 74 systemic and 84 post filter samples from patients undergoing RCA for CRRT at the University Medicine of Greifswald. The systemic samples showed concordant results on all analyzers with median iCa concentrations ranging from 1.07 to 1.16 mmol/L. The medians of iCa concentrations for post filter samples ranged from 0.21 to 0.50 mmol/L. Results of >70 % of the post filter samples would lead to major differences in decisions regarding citrate flow depending on the instrument used. Measurements of iCa in post filter samples may give misleading information in monitoring the RCA. Recommendations of the dialysis Manufacturer need to be revised. Meanwhile, little weight should be given to post filter iCa. Reference methods for low iCa in whole blood containing citrate should be established.

Sigrun Friesecke - One of the best experts on this subject based on the ideXlab platform.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Introduction Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer. The iCa concentrations of systemic and post filter samples were measured using six distinct, frequently used blood gas analyzers. We obtained iCa results of 74 systemic and 84 post filter samples from patients undergoing RCA for CRRT at the University Medicine of Greifswald. The systemic samples showed concordant results on all analyzers with median iCa concentrations ranging from 1.07 to 1.16 mmol/L. The medians of iCa concentrations for post filter samples ranged from 0.21 to 0.50 mmol/L. Results of >70 % of the post filter samples would lead to major differences in decisions regarding citrate flow depending on the instrument used. Measurements of iCa in post filter samples may give misleading information in monitoring the RCA. Recommendations of the dialysis Manufacturer need to be revised. Meanwhile, little weight should be given to post filter iCa. Reference methods for low iCa in whole blood containing citrate should be established.

Maximilian Helm - One of the best experts on this subject based on the ideXlab platform.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Introduction Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer. The iCa concentrations of systemic and post filter samples were measured using six distinct, frequently used blood gas analyzers. We obtained iCa results of 74 systemic and 84 post filter samples from patients undergoing RCA for CRRT at the University Medicine of Greifswald. The systemic samples showed concordant results on all analyzers with median iCa concentrations ranging from 1.07 to 1.16 mmol/L. The medians of iCa concentrations for post filter samples ranged from 0.21 to 0.50 mmol/L. Results of >70 % of the post filter samples would lead to major differences in decisions regarding citrate flow depending on the instrument used. Measurements of iCa in post filter samples may give misleading information in monitoring the RCA. Recommendations of the dialysis Manufacturer need to be revised. Meanwhile, little weight should be given to post filter iCa. Reference methods for low iCa in whole blood containing citrate should be established.

Sixten Selleng - One of the best experts on this subject based on the ideXlab platform.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Introduction Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer.

  • discrepant post filter ionized calcium concentrations by common blood gas analyzers in crrt using regional citrate anticoagulation
    Critical Care, 2015
    Co-Authors: Patrik Schwarzer, Svenolaf Kuhn, Sylvia Stracke, Matthias Grundling, Stephan Knigge, Sixten Selleng, Maximilian Helm, Sigrun Friesecke, Peter Abel, Anders Kallner
    Abstract:

    Ionized calcium (iCa) concentration is often used in critical care and measured using blood gas analyzers at the point of care. Controlling and adjusting regional citrate anticoagulation (RCA) for continuous renal replacement therapy (CRRT) involves measuring the iCa concentration in two samples: systemic with physiological iCa concentrations and post filter samples with very low iCa concentrations. However, modern blood gas analyzers are optimized for physiological iCa concentrations which might make them less suitable for measuring low iCa in blood with a high concentration of citrate. We present results of iCa measurements from six different blood gas analyzers and the impact on clinical decisions based on the recommendations of the dialysis’ Device Manufacturer. The iCa concentrations of systemic and post filter samples were measured using six distinct, frequently used blood gas analyzers. We obtained iCa results of 74 systemic and 84 post filter samples from patients undergoing RCA for CRRT at the University Medicine of Greifswald. The systemic samples showed concordant results on all analyzers with median iCa concentrations ranging from 1.07 to 1.16 mmol/L. The medians of iCa concentrations for post filter samples ranged from 0.21 to 0.50 mmol/L. Results of >70 % of the post filter samples would lead to major differences in decisions regarding citrate flow depending on the instrument used. Measurements of iCa in post filter samples may give misleading information in monitoring the RCA. Recommendations of the dialysis Manufacturer need to be revised. Meanwhile, little weight should be given to post filter iCa. Reference methods for low iCa in whole blood containing citrate should be established.