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Brito Iva - One of the best experts on this subject based on the ideXlab platform.

  • Espectro clínico das manifestações musculoesqueléticas da diabetes mellitus
    Sociedade Portuguesa de Endocrinologia Diabetes e Metabolismo. Published by Elsevier España S.L.U., 2016
    Co-Authors: Marques, Ana Raquel, Brito Iva
    Abstract:

    ResumoIntrodução e objetivoA diabetes mellitus pode estar associada a uma grande variedade de manifestações musculoesqueléticas, muitas vezes subclínicas, correlacionadas com tempo de evolução da diabetes e com controlo glicémico, que devem ser reconhecidas e tratadas atempadamente. Na maioria dos casos, estão associadas a incapacidade física e dor, e a sua abordagem precoce é importante para melhorar a qualidade de vida dos doentes. O objetivo é fazer uma revisão sobre as manifestações musculoesqueléticas da diabetes, focando‐se na sua apresentação clínica, abordagem, diagnóstico e tratamento.MétodosFoi realizada uma pesquisa de artigos na Pubmed, National Guideline Clearinghouse, Canadian Medical Association Infobase, The Cochrane Library, DARE, Bandolier e TRIP, de guidelines, meta‐análises, revisões sistemáticas e ensaios clínicos aleatorizados, publicados nos últimos 10 anos, nas línguas portuguesa, inglesa e espanhola, usando os seguintes termos MESH: diabetes mellitus, doenças musculoesqueléticas e prevalência.Corpo da revisãoAs manifestações musculoesqueléticas podem ser divididas em 3 grupos: manifestações intrínsecas da diabetes – enfarte muscular diabético; as mais comuns na diabetes, como a síndrome da mobilidade articular limitada, síndrome da mão diabética (síndrome da mão rígida/queiroartropatia diabética), capsulite adesiva, dedo em gatilho, contratura de Dupuytren, periartrite calcificada – mais frequentes – e, por último, manifestações com associação possível com os fatores de risco da diabetes, como a hiperostose esquelética idiopática difusa, gota e osteoartrite.ConclusõesExiste uma associação entre as manifestações musculoesqueléticas e a diabetes, que ocorrem mais frequentemente na mão e ombro. O reconhecimento da associação entre a diabetes e a capsulite adesiva, contratura de Dupruyten e dedo em gatilho, facilita o seu correto diagnóstico, no contexto da diabetes, e o início rápido e apropriado do tratamento, que pode incluir uma otimização do controlo glicémico. No entanto, estudos adicionais são necessários para esclarecimento da sua fisiopatologia e a sua correlação com a progressão da doença.AbstractIntroduction and aimDiabetes Mellitus is associated with several musculoskeletal disorders, whose development is dependent on the duration and metabolic control of Diabetes. These should be recognized and treated as soon as possible. In the majority of cases, these manifestations are associated with physical incapacity and pain, and an early diagnose is important to improve the patient's quality of life. The present review addresses both the common and uncommon manifestations of Diabetes, focusing on their clinical presentations, diagnosis, management and treatment.MethodsA research, in Pubmed, National Guideline Clearinghouse, Canadian Medical Association Infobase, The Cochrane Library, DARE, Bandolier e TRIP, of guidelines, meta‐analyses, systematic reviews and randomized trials, published in the last ten years, in Portuguese, English and Spanish, was done, using the following MESH terms: diabetes mellitus, musculoskeletal diseases and prevalence.ReviewThe musculoskeletal disorders can be divided into three categories: conditions unique to Diabetes ‐ Diabetic muscular infarction; conditions more frequent in Diabetes, such as limited joint mobility, Diabetic hand syndrome/Diabetic Cheiroarthropathy, adhesive capsulitis, trigger finger, Dupuytren's contracture, periarthritis; and at last, conditions sharing risk factors of Diabetes, such as Diffuse Idiopathic Skeletal Hyperostosis, gout and osteoarthritis.ConclusionsThere is a relation between musculosketetal disorders and Diabetes Mellitus. Hand and shoulder disorders occur more frequently than other musculoskeletal manifestations of diabetes. Recognition of the association between diabetes and shoulder adhesive capsulitis, Dupuytren's contracture and stenosing flexor tenosynovitis facilitates their correct diagnosis in the setting of diabetes and prompt initiation of appropriate treatment, which may include optimizing glycemic control. However, more studies are necessary to clarify the physiopathology and the correlation with the progression of the disease

Marques, Ana Raquel - One of the best experts on this subject based on the ideXlab platform.

  • Espectro clínico das manifestações musculoesqueléticas da diabetes mellitus
    Sociedade Portuguesa de Endocrinologia Diabetes e Metabolismo. Published by Elsevier España S.L.U., 2016
    Co-Authors: Marques, Ana Raquel, Brito Iva
    Abstract:

    ResumoIntrodução e objetivoA diabetes mellitus pode estar associada a uma grande variedade de manifestações musculoesqueléticas, muitas vezes subclínicas, correlacionadas com tempo de evolução da diabetes e com controlo glicémico, que devem ser reconhecidas e tratadas atempadamente. Na maioria dos casos, estão associadas a incapacidade física e dor, e a sua abordagem precoce é importante para melhorar a qualidade de vida dos doentes. O objetivo é fazer uma revisão sobre as manifestações musculoesqueléticas da diabetes, focando‐se na sua apresentação clínica, abordagem, diagnóstico e tratamento.MétodosFoi realizada uma pesquisa de artigos na Pubmed, National Guideline Clearinghouse, Canadian Medical Association Infobase, The Cochrane Library, DARE, Bandolier e TRIP, de guidelines, meta‐análises, revisões sistemáticas e ensaios clínicos aleatorizados, publicados nos últimos 10 anos, nas línguas portuguesa, inglesa e espanhola, usando os seguintes termos MESH: diabetes mellitus, doenças musculoesqueléticas e prevalência.Corpo da revisãoAs manifestações musculoesqueléticas podem ser divididas em 3 grupos: manifestações intrínsecas da diabetes – enfarte muscular diabético; as mais comuns na diabetes, como a síndrome da mobilidade articular limitada, síndrome da mão diabética (síndrome da mão rígida/queiroartropatia diabética), capsulite adesiva, dedo em gatilho, contratura de Dupuytren, periartrite calcificada – mais frequentes – e, por último, manifestações com associação possível com os fatores de risco da diabetes, como a hiperostose esquelética idiopática difusa, gota e osteoartrite.ConclusõesExiste uma associação entre as manifestações musculoesqueléticas e a diabetes, que ocorrem mais frequentemente na mão e ombro. O reconhecimento da associação entre a diabetes e a capsulite adesiva, contratura de Dupruyten e dedo em gatilho, facilita o seu correto diagnóstico, no contexto da diabetes, e o início rápido e apropriado do tratamento, que pode incluir uma otimização do controlo glicémico. No entanto, estudos adicionais são necessários para esclarecimento da sua fisiopatologia e a sua correlação com a progressão da doença.AbstractIntroduction and aimDiabetes Mellitus is associated with several musculoskeletal disorders, whose development is dependent on the duration and metabolic control of Diabetes. These should be recognized and treated as soon as possible. In the majority of cases, these manifestations are associated with physical incapacity and pain, and an early diagnose is important to improve the patient's quality of life. The present review addresses both the common and uncommon manifestations of Diabetes, focusing on their clinical presentations, diagnosis, management and treatment.MethodsA research, in Pubmed, National Guideline Clearinghouse, Canadian Medical Association Infobase, The Cochrane Library, DARE, Bandolier e TRIP, of guidelines, meta‐analyses, systematic reviews and randomized trials, published in the last ten years, in Portuguese, English and Spanish, was done, using the following MESH terms: diabetes mellitus, musculoskeletal diseases and prevalence.ReviewThe musculoskeletal disorders can be divided into three categories: conditions unique to Diabetes ‐ Diabetic muscular infarction; conditions more frequent in Diabetes, such as limited joint mobility, Diabetic hand syndrome/Diabetic Cheiroarthropathy, adhesive capsulitis, trigger finger, Dupuytren's contracture, periarthritis; and at last, conditions sharing risk factors of Diabetes, such as Diffuse Idiopathic Skeletal Hyperostosis, gout and osteoarthritis.ConclusionsThere is a relation between musculosketetal disorders and Diabetes Mellitus. Hand and shoulder disorders occur more frequently than other musculoskeletal manifestations of diabetes. Recognition of the association between diabetes and shoulder adhesive capsulitis, Dupuytren's contracture and stenosing flexor tenosynovitis facilitates their correct diagnosis in the setting of diabetes and prompt initiation of appropriate treatment, which may include optimizing glycemic control. However, more studies are necessary to clarify the physiopathology and the correlation with the progression of the disease

Sarpel T. - One of the best experts on this subject based on the ideXlab platform.

  • An overlooked rheumatologic manifestation of diabetes: Diabetic Cheiroarthropathy
    'Springer Science and Business Media LLC', 2019
    Co-Authors: Gokcen N., Cetinkaya Altuntas S., Coskun Benlidayi, Sert M., Nazlican E., Sarpel T.
    Abstract:

    PubMedID: 30712127Objectives: The objectives of the study were to analyze the clinical characteristic of Diabetic Cheiroarthropathy (DCA) in patients with type 1 diabetes mellitus (DM), type 2 DM, and prediabetes and to evaluate the frequency of DCA among groups. Method: The cross-sectional study was conducted at the Division of Endocrinology and Metabolism outpatient clinic over a 14-month period. A total of 239 patients (160 female, 79 male), who had type 1 DM, type 2 DM, and prediabetes, were enrolled. The demographics, clinical variables, and laboratory outcomes were recorded. Diabetic Cheiroarthropathy was defined according to physical examination. The functional disability of patients with DCA was assessed by the self-administered questionnaire (disabilities of the arm, shoulder and hand-DASH). Results: Diabetic Cheiroarthropathy was determined in 35.1% of all patients. The frequency of DCA was higher in patients with prediabetes (x 2 = 0.009, post hoc power = 0.794). According to the logistic regression analysis, prediabetes (OR = 4.52, 95% CI 2.16–9.47, p < 0.001), presence of polyneuropathy (OR = 3.82, 95% CI 1.61–9.07, p = 0.002), and fasting glucose level (OR = 1.01, 95% CI 1.00–1.01, p = 0.004) found as the most effective risk factors in determining DCA. DASH disability scores were significantly higher in preDiabetic patients than that in type 2 DM group (p = 0.021). Conclusion: High frequency of DCA and impaired hand function are observed in preDiabetic patients. Musculoskeletal manifestations can emerge as an early sign of Diabetic status. Also, people who suffer from hand involvement should be examined for diabetes along with rheumatologic diseases. © 2019, International League of Associations for Rheumatology (ILAR)

J. J. Hamblin - One of the best experts on this subject based on the ideXlab platform.

  • British Journal of Rheumatology 1996;35:676-679 ULTRASONOGRAPHIC FEATURES OF Diabetic Cheiroarthropathy
    2015
    Co-Authors: A. A. Ismail, B. Dasgupta, A. B. Tanqueray, J. J. Hamblin
    Abstract:

    Ultrasonography was used to measure flexor tendon sheath thickness in 14 insulin-dependent (IDDM) Diabetics with Diabetic Cheiroarthropathy (DCA) and compared to 17 IDDM patients without DCA along with 10 healthy volunteers. Assessment was also made of the presence of systemic Diabetic microvascular disease complications. A blinded visual 'eyeball ' report on the ultrasound scans by a radiologist found hypoechoic thickening of the flexor tendon sheaths in 12 of the 14 patients with DCA, three of the 17 unaffected Diabetics and two of the healthy volunteers (Fisher's exact, P < 0.001). However, further quantitation of tendon sheath thickness separated patients with DCA from others. In all patients with DCA, tendon sheath thickness was> 1 mm (median 1.8 mm, range 1.0-2.3 mm) and < 1 mm in the other two groups (medians 0.6 and 0.5 mm, range 0.3-1.0 mm) (Kruskal-Wallis, P < 0.001). All patients with DCA had evidence of systemic microvascular disease complications, particularly proliferative retinopathy (82%). It appears that flexor tendon sheath thickening in the hand is an integral part of the pathology in DCA and is easily demonstrated by ultrasound. It is closely associated with overt Diabetic raicrovascular disease complications. KEY WORDS: Diabetic Cheiroarthropathy, Tendon sheath, Insulin-dependent diabetes, Diabetic microvascular complications. A LARGE proportion of morbidity and mortality due to diabetes mellitus is due to chronic microvascular complications such as retinopathy, nephropathy and neuropathy. An under-recognized complication is Diabetic Cheiroarthropathy (DCA). DCA is a syndrom

Gail Nunlee-bland - One of the best experts on this subject based on the ideXlab platform.

  • Diabetic Cheiroarthropathy: A Case Report and Review of the Literature
    Hindawi Limited, 2013
    Co-Authors: Rabia Cherqaoui, Sheldon Mckenzie, Gail Nunlee-bland
    Abstract:

    Diabetes mellitus is associated with a wide variety of rheumatologic manifestations which can significantly affect a patient's quality of life. One of these manifestations includes Diabetic Cheiroarthropathy (DCA) which affects the hands. We review a case of a 28-year-old female patient with type 1 diabetes mellitus who was diagnosed with DCA after complaining of limited movements of all joints in her hands and tightening of the skin. We examine how the diagnosis was made, the treatment administered, and the successful clinical outcome. Clinicians should be able to identify and treat this affliction. The diagnosis is mainly clinical. It is imperative to remember that the presence of DCA carries with it a significant relationship with microvascular disease