The Experts below are selected from a list of 1791 Experts worldwide ranked by ideXlab platform
Jianbo Wang - One of the best experts on this subject based on the ideXlab platform.
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rh i catalyzed intramolecular 2 2 1 cycloaddition of diynes with the n terminal of the Diazo Group
Organic chemistry frontiers, 2019Co-Authors: Bo Wang, Jianbo Wang, Yuankai Wang, Zixuan WangAbstract:A new type of Rh(I)-catalyzed intramolecular [2 + 2 + 1] cycloaddition of diynes and the N-terminal of a Diazo moiety is reported. This study is the first attempt to combine oxidative cyclometallation with carbene migratory insertion. This reaction is suggested to involve the initial oxidative cyclometallation, followed by migratory nitrogen insertion and reductive elimination.
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Nucleophilic Addition to C=O and C=N Bonds by Nucleophiles Containing a Diazo Group
Synlett, 2005Co-Authors: Yonghua Zhao, Jianbo WangAbstract:This account summarizes recent developments in the nucleophilic addition reaction of Diazo compound derived anion or enolate with electrophilic C=O and C=N bonds. Subsequent reaction of the addition products under transition-metal-catalyzed conditions, as well as their synthetic utility, are also presented.
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An efficient synthesis of aryl α-keto esters
Tetrahedron Letters, 2005Co-Authors: Lingling Peng, Fang Xie, Xiu Zhang, Jianbo WangAbstract:A new one-pot approach for the synthesis of aryl α-keto ester based on the Diazo transfer and oxidation of Diazo Group is developed.
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Diazo decomposition in the presence of tributyltin hydride reduction of α Diazo carbonyl compounds
Tetrahedron, 2000Co-Authors: Zhaohui Qu, Bei Chen, Jianbo WangAbstract:Abstract The Diazo Group of a series of α-Diazo carbonyl compounds can be reduced to the corresponding CH2 Group by Bu3SnH under Cu(acac)2-catalytic or photochemical conditions. The mechanistic aspects of this reaction were investigated in some detail, and a possible reaction pathway was discussed.
Vladimir Gevorgyan - One of the best experts on this subject based on the ideXlab platform.
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a new reactivity mode for the Diazo Group diastereoselective 1 3 aminoalkylation reaction of β amino α Diazoesters to give triazolines
ChemInform, 2014Co-Authors: Alexey Kuznetsov, Anton V. Gulevich, Donald J. Wink, Vladimir GevorgyanAbstract:This method presents a novel mode of reactivity for the Diazo Group: an intramolecular aminoalkylation of β-amino-α-Diazoesters via a 1,3-addition of a nucleophile and an electrophile to the Diazo Group yielding 1,2,3-triazolines.
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A New Reactivity Mode for the Diazo Group: Diastereoselective 1,3‐Aminoalkylation Reaction of β‐Amino‐α‐Diazoesters to Give Triazolines.
ChemInform, 2014Co-Authors: Alexey Kuznetsov, Anton V. Gulevich, Donald J. Wink, Vladimir GevorgyanAbstract:This method presents a novel mode of reactivity for the Diazo Group: an intramolecular aminoalkylation of β-amino-α-Diazoesters via a 1,3-addition of a nucleophile and an electrophile to the Diazo Group yielding 1,2,3-triazolines.
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a new reactivity mode for the Diazo Group diastereoselective 1 3 aminoalkylation reaction of β amino α Diazoesters to give triazolines
Angewandte Chemie, 2014Co-Authors: Alexey Kuznetsov, Anton V. Gulevich, Donald J. Wink, Vladimir GevorgyanAbstract:A novel mode of reactivity for the Diazo Group, the 1,3-addition of a nucleophile and an electrophile to the Diazo Group, has been realized in the intramolecular aminoalkylation of β-amino-α-Diazoesters to form tetrasubstituted 1,2,3-triazolines. The reaction exhibited a broad scope, good functional Group tolerance, and excellent diastereoselectivity. In addition, a new Au-catalyzed intramolecular transannulation reaction of the obtained propargyl triazolines to give pyrroles has been discovered.
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A New Reactivity Mode for the Diazo Group: Diastereoselective 1,3‐Aminoalkylation Reaction of β‐Amino‐α‐Diazoesters To Give Triazolines
Angewandte Chemie, 2014Co-Authors: Alexey Kuznetsov, Anton V. Gulevich, Donald J. Wink, Vladimir GevorgyanAbstract:A novel mode of reactivity for the Diazo Group, the 1,3-addition of a nucleophile and an electrophile to the Diazo Group, has been realized in the intramolecular aminoalkylation of β-amino-α-Diazoesters to form tetrasubstituted 1,2,3-triazolines. The reaction exhibited a broad scope, good functional Group tolerance, and excellent diastereoselectivity. In addition, a new Au-catalyzed intramolecular transannulation reaction of the obtained propargyl triazolines to give pyrroles has been discovered.
Graham K Murphy - One of the best experts on this subject based on the ideXlab platform.
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denitrogenative hydrofluorination of aromatic aldehyde hydrazones using difluoroiodo toluene
Organic and Biomolecular Chemistry, 2016Co-Authors: Kaivalya G Kulkarni, Boris Miokovic, Matthew Sauder, Graham K MurphyAbstract:An operationally simple conversion of aromatic aldehyde hydrazones to monofluoromethylated arenes is reported. The hypervalent iodine reagent TolIF2 serves as an oxidant, converting the hydrazone to the corresponding Diazo compounds. The by-product of the oxidation process, HF, is consumed in situ by a denitrogenative hydrofluorination reaction of the Diazo Group.
Albert Padwa - One of the best experts on this subject based on the ideXlab platform.
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Rh(II)-Catalyzed Reactions of Differentially Substituted Bis(Diazo) Functionalities.
ChemInform, 2013Co-Authors: Sara A. Bonderoff, Albert PadwaAbstract:The bis(Diazo)compound (I) undergoes chemoselective cyclopropanation, OH- or NH-insertion without affecting the second Diazo Group present in the same molecule.
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Rh(II)-catalyzed reactions of differentially substituted bis(Diazo) functionalities.
Organic Letters, 2013Co-Authors: Sara A. Bonderoff, Albert PadwaAbstract:The chemoselective reaction of donor/acceptor (D/A) and acceptor/acceptor (A/A) Diazo moieties in the same molecule was examined using 3-Diazo-1-(ethyl 2-Diazomalonyl)indolin-2-one under rhodium(II) catalysis. The D/A Diazo Group undergoes selective cyclopropanation as well as XH-insertion, leaving behind the second Diazo Group for a further intramolecular dipolar cycloaddition reaction.
Ronald G Brisbois - One of the best experts on this subject based on the ideXlab platform.
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detrifluoroacetylative Diazo Group transfer e 1 Diazo 4 phenyl 3 buten 2 one
Organic Syntheses, 2003Co-Authors: Rick L Danheiser, Raymond F Miller, Ronald G BrisboisAbstract:Detrifluoroacetylative Diazo Group transfer: (E)-1-Diazo-4-phenyl-3-buten-2-one product: (E)-1-Diazo-4-phenyl-3-buten-2-one product: α-Diazoacetophenone Keywords: acylation; acylation; condensation, ester-active methylene condensation; deacylation; Diazo transfer; acetonitrile; assay methods, for butyllithium, with 2-butanol, menthol, 2-pentanol, or 2-propanol, 1,10-phenanthroline indicator; 1,1,1,3,3,3-hexamethyldisilazane; tetrahydrofuran; triethylamine; acetonitrile; Diazo compounds; methanesulfonyl azide, shock sensitive
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Organic Syntheses - Detrifluoroacetylative Diazo Group Transfer: (E)‐1‐Diazo‐4‐Phenyl‐3‐Buten‐2‐One
Organic Syntheses, 2003Co-Authors: Rick L Danheiser, Raymond F Miller, Ronald G BrisboisAbstract:Detrifluoroacetylative Diazo Group transfer: (E)-1-Diazo-4-phenyl-3-buten-2-one product: (E)-1-Diazo-4-phenyl-3-buten-2-one product: α-Diazoacetophenone Keywords: acylation; acylation; condensation, ester-active methylene condensation; deacylation; Diazo transfer; acetonitrile; assay methods, for butyllithium, with 2-butanol, menthol, 2-pentanol, or 2-propanol, 1,10-phenanthroline indicator; 1,1,1,3,3,3-hexamethyldisilazane; tetrahydrofuran; triethylamine; acetonitrile; Diazo compounds; methanesulfonyl azide, shock sensitive