The Experts below are selected from a list of 264 Experts worldwide ranked by ideXlab platform
Justine M. Abais-battad - One of the best experts on this subject based on the ideXlab platform.
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Dietary Protein: Mechanisms Influencing Hypertension and Renal Disease
Current hypertension reports, 2020Co-Authors: John Henry Dasinger, Daniel J. Fehrenbach, Justine M. Abais-battadAbstract:This review will provide an in-depth coverage of the epidemiological and pre-clinical literature surrounding the role of Dietary Protein in hypertension, with a special emphasis on the history of our work on the Dahl salt-sensitive rat. Our studies have dedicated much effort into understanding the relationship between Dietary Protein and its effect on the development of salt-sensitive hypertension and renal injury. Our evidence over the last 15 years have demonstrated that both the source and amount of Dietary Protein can influence the severity of disease, where we have determined mechanisms related to immunity, the maternal environment during pregnancy, and more recently the gut microbiota, which significantly contribute to these diet-induced effects. Deeper understanding of these Dietary Protein-related mechanisms may provide insight on the plausibility of Dietary modifications as future therapeutic avenues for hypertension and renal disease.
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Dietary Protein: Mechanisms Influencing Hypertension and Renal Disease
Current Hypertension Reports, 2020Co-Authors: John Henry Dasinger, Daniel J. Fehrenbach, Justine M. Abais-battadAbstract:Purpose of Review This review will provide an in-depth coverage of the epidemiological and pre-clinical literature surrounding the role of Dietary Protein in hypertension, with a special emphasis on the history of our work on the Dahl salt-sensitive rat. Recent Findings Our studies have dedicated much effort into understanding the relationship between Dietary Protein and its effect on the development of salt-sensitive hypertension and renal injury. Our evidence over the last 15 years have demonstrated that both the source and amount of Dietary Protein can influence the severity of disease, where we have determined mechanisms related to immunity, the maternal environment during pregnancy, and more recently the gut microbiota, which significantly contribute to these diet-induced effects. Summary Deeper understanding of these Dietary Protein-related mechanisms may provide insight on the plausibility of Dietary modifications as future therapeutic avenues for hypertension and renal disease.
Pedro Cortes - One of the best experts on this subject based on the ideXlab platform.
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the role of Dietary Protein restriction in progressive azotemia
The New England Journal of Medicine, 1994Co-Authors: Robert G Narins, Pedro CortesAbstract:In rats, renal diseases progress to the end stage, but the rate of progression can be slowed dramatically by Dietary Protein restriction1. In humans, most renal diseases also progress to death due to uremia, unless transplantation or dialysis is provided2. Despite several studies to the contrary, the results of the Modification of Diet in Renal Diseases (MDRD) study, reported in this issue of the Journal by Klahr et al., suggest that the progression of renal diseases in humans is only minimally slowed by Dietary Protein restriction3. What accounts for these differences? In the studies in rats the . . .
John Henry Dasinger - One of the best experts on this subject based on the ideXlab platform.
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Dietary Protein: Mechanisms Influencing Hypertension and Renal Disease
Current hypertension reports, 2020Co-Authors: John Henry Dasinger, Daniel J. Fehrenbach, Justine M. Abais-battadAbstract:This review will provide an in-depth coverage of the epidemiological and pre-clinical literature surrounding the role of Dietary Protein in hypertension, with a special emphasis on the history of our work on the Dahl salt-sensitive rat. Our studies have dedicated much effort into understanding the relationship between Dietary Protein and its effect on the development of salt-sensitive hypertension and renal injury. Our evidence over the last 15 years have demonstrated that both the source and amount of Dietary Protein can influence the severity of disease, where we have determined mechanisms related to immunity, the maternal environment during pregnancy, and more recently the gut microbiota, which significantly contribute to these diet-induced effects. Deeper understanding of these Dietary Protein-related mechanisms may provide insight on the plausibility of Dietary modifications as future therapeutic avenues for hypertension and renal disease.
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Dietary Protein: Mechanisms Influencing Hypertension and Renal Disease
Current Hypertension Reports, 2020Co-Authors: John Henry Dasinger, Daniel J. Fehrenbach, Justine M. Abais-battadAbstract:Purpose of Review This review will provide an in-depth coverage of the epidemiological and pre-clinical literature surrounding the role of Dietary Protein in hypertension, with a special emphasis on the history of our work on the Dahl salt-sensitive rat. Recent Findings Our studies have dedicated much effort into understanding the relationship between Dietary Protein and its effect on the development of salt-sensitive hypertension and renal injury. Our evidence over the last 15 years have demonstrated that both the source and amount of Dietary Protein can influence the severity of disease, where we have determined mechanisms related to immunity, the maternal environment during pregnancy, and more recently the gut microbiota, which significantly contribute to these diet-induced effects. Summary Deeper understanding of these Dietary Protein-related mechanisms may provide insight on the plausibility of Dietary modifications as future therapeutic avenues for hypertension and renal disease.
Andrew S Levey - One of the best experts on this subject based on the ideXlab platform.
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Dietary Protein and renal function.
Journal of The American Society of Nephrology, 1993Co-Authors: A J King, Andrew S LeveyAbstract:Protein intake has been recognized as a modulator of renal function for over half a century. This review analyzes the renal response induced by changes in habitual Protein intake and with acute amino acid infusion or a meat meal in humans and animals. The pattern and magnitude of changes in GFR and creatinine clearance are examined along with a discussion of the effect of the variability of these measurements among individuals and populations on the interpretation of clinical studies. Potential mechanisms of Protein-induced changes in GFR and creatinine clearance are examined, including changes in the hormonal milieu, glomerular hemodynamics, and other intrarenal processes. Habitual Dietary Protein consumption varies significantly with respect to age, gender, and lean body mass--factors that are well known to influence GFR. This correlation raises the possibility that (1) variation in Dietary Protein intake may account, at least in part, for the differences in renal function among individuals; and (2) the level of Protein intake should be assessed in defining the normal range of renal function.
Robert G Narins - One of the best experts on this subject based on the ideXlab platform.
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the role of Dietary Protein restriction in progressive azotemia
The New England Journal of Medicine, 1994Co-Authors: Robert G Narins, Pedro CortesAbstract:In rats, renal diseases progress to the end stage, but the rate of progression can be slowed dramatically by Dietary Protein restriction1. In humans, most renal diseases also progress to death due to uremia, unless transplantation or dialysis is provided2. Despite several studies to the contrary, the results of the Modification of Diet in Renal Diseases (MDRD) study, reported in this issue of the Journal by Klahr et al., suggest that the progression of renal diseases in humans is only minimally slowed by Dietary Protein restriction3. What accounts for these differences? In the studies in rats the . . .