The Experts below are selected from a list of 219 Experts worldwide ranked by ideXlab platform

Ronald A. Hinder - One of the best experts on this subject based on the ideXlab platform.

  • Insights Gained from Symptom Evaluation of Esophageal Motility Disorders: A Review of 4,215 Patients
    Digestion, 2012
    Co-Authors: Kazuto Tsuboi, Ronald A. Hinder, Tom R. Demeester, Charles J Filipi, Masato Hoshino, Ananth Srinivasan, Fumiaki Yano, Sumeet K. Mittal
    Abstract:

    Background/Aims: Achalasia (Ach), Diffuse Esophageal Spasm (DES), nutcracker esophagus (NE), and nonspecific motility disorder (NSMD) are described primary Esophageal body motility

  • A Comprehensive Appraisal of the Surgical Treatment of Diffuse Esophageal Spasm
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2007
    Co-Authors: Cristina Almansa, Ronald A. Hinder, C. Daniel Smith, Sami R. Achem
    Abstract:

    Diffuse Esophageal Spasm is a motility disorder of undetermined cause. The optimal treatment remains controversial, and evidence-based data are lacking. Several medical treatment modalities have been proposed, but none has emerged as the treatment of choice. Patients who do not respond to medical therapy may be considered for surgical treatment. The surgical treatment of Diffuse Esophageal Spasm is based on similar principles to the treatment of achalasia. A long Esophageal myotomy is done to divide the hypertrophied circular muscle that is frequently noted in Diffuse Esophageal Spasm. To protect against postoperative reflux, an antireflux procedure may be added. However, the surgical treatment of Diffuse Esophageal Spasm has not been subjected to randomized clinical trials. The purpose of this article is to provide a review of the available literature regarding the surgical management of the Diffuse Esophageal Spasm. In particular, we offer an appraisal of surgical outcomes, the effects of surgery on manometric and radiologic parameters (when available), complications, and mortality.

  • thoracoscopic Esophageal myotomy a surgical technique for achalasia Diffuse Esophageal Spasm and nutcracker esophagus
    Surgical Endoscopy and Other Interventional Techniques, 1994
    Co-Authors: Charles J Filipi, Ronald A. Hinder
    Abstract:

    Thoracoscopic myotomy has been performed for Diffuse Esophageal Spasm "nutcracker esophagus" and achalasia. Technical considerations for thoracoscopic long myotomy such as trocar placement, length of myotomy, extent of myotomy distal to the gastroEsophageal junction, hiatal closure, fundoplication and degree of Esophageal mobilization are discussed.

Charles J Filipi - One of the best experts on this subject based on the ideXlab platform.

Hyung Hun Kim - One of the best experts on this subject based on the ideXlab platform.

  • A case of symptomatic Diffuse Esophageal Spasm during multiple rapid swallowing test on high-resolution manometry.
    Journal of neurogastroenterology and motility, 2010
    Co-Authors: Eun Mi Lee, Moo In Park, Won Moon, Kyung Mi Kim, Seun Ja Park, Hyung Hun Kim
    Abstract:

    Diffuse Esophageal Spasm (DES) is an uncommon motility disorder of unknown etiology in which the abnormal motility has been offered as a possible cause for the patient's dysphagia or chest pain. Esophageal manometry is the gold standard for the diagnosis of DES and the diagnostic hallmark is identification of simultaneous contractions in at least 20% of wet swallows, alternating with normal peristalsis. Recently, a new diagnostic technique, high-resolution manometry has been reported to improve the accuracy and detail in describing Esophageal function. We report a female patient with intermittent dysphagia and chest pain occurring only when swallowing a large amount of water. On HRM, this patient had Esophageal Spasms, increased pressurization front velocity attributable to rapid contractile wave front, associated with symptoms, which were provoked by a multiple rapid swallowing test, and thereby was diagnosed with DES.

Meinhard Classen - One of the best experts on this subject based on the ideXlab platform.

  • Treatment of symptomatic Diffuse Esophageal Spasm by endoscopic injections of botulinum toxin: a prospective study with long-term follow-up.
    Gastrointestinal endoscopy, 2001
    Co-Authors: Martin Storr, Hans-dieter Allescher, Thomas Rösch, P. Born, N. Weigert, Meinhard Classen
    Abstract:

    Abstract Background: Diffuse Esophageal Spasm is a rare Esophageal motility disorder for which there are no satisfactory pharmacologic alternatives for treatment. The aim of this study was to investigate whether botulinum toxin (BTX) injection is an effective short- and long-term treatment for patients with symptoms caused by Diffuse Esophageal Spasm. Whether recurrence of clinical symptoms can be successfully retreated by BTX injection was also studied. Methods: Nine symptomatic patients (6 women, 3 men; 57-86 years) with manometrically proven Diffuse Esophageal Spasm underwent BTX injection. One hundred IU BTX were diluted in l0 mL of saline solution and injected endoscopically at multiple sites along the Esophageal wall beginning in the region of the lower Esophageal sphincter and moving proximally in 1- to 1.5-cm intervals, and into endoscopically visible contraction rings. Symptom scores based on an analogue scale for dysphagia, regurgitation, and noncardiac chest pain were assessed before and after therapy, 1 day thereafter, and at 1 and 6 months. Results: Symptoms improved immediately in 7 (78%) patients after 1 injection session. After 4 weeks 8 (89%) patients were in remission with a decrease in total symptom score. The total symptom score decreased from a median 8.0 (interquartile range: 6.75; 9.0) before treatment to 2.0 (1.5; 3.75) after 1 day ( p p Conclusions: BTX injection at several levels of the tubular esophagus is an effective treatment for patients with symptoms caused by Diffuse Esophageal Spasm. Symptom relapse can be effectively treated by repeated BTX injection.

Martin Storr - One of the best experts on this subject based on the ideXlab platform.

  • Botulinum toxin in the treatment of Diffuse Esophageal Spasm.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2010
    Co-Authors: Mohammad Bashashati, Christopher N. Andrews, S. Ghosh, Martin Storr
    Abstract:

    SUMMARY.Diffuse Esophageal Spasm is a primary Esophageal motility disorder. The prevalence is 3–10% in patients with dysphagia and treatment options are limited. This review summarizes the treatment of Diffuse Esophageal Spasm, including pharmacotherapy, endoscopic treatment, and surgical treatment

  • Treatment of symptomatic Diffuse Esophageal Spasm by endoscopic injections of botulinum toxin: a prospective study with long-term follow-up.
    Gastrointestinal endoscopy, 2001
    Co-Authors: Martin Storr, Hans-dieter Allescher, Thomas Rösch, P. Born, N. Weigert, Meinhard Classen
    Abstract:

    Abstract Background: Diffuse Esophageal Spasm is a rare Esophageal motility disorder for which there are no satisfactory pharmacologic alternatives for treatment. The aim of this study was to investigate whether botulinum toxin (BTX) injection is an effective short- and long-term treatment for patients with symptoms caused by Diffuse Esophageal Spasm. Whether recurrence of clinical symptoms can be successfully retreated by BTX injection was also studied. Methods: Nine symptomatic patients (6 women, 3 men; 57-86 years) with manometrically proven Diffuse Esophageal Spasm underwent BTX injection. One hundred IU BTX were diluted in l0 mL of saline solution and injected endoscopically at multiple sites along the Esophageal wall beginning in the region of the lower Esophageal sphincter and moving proximally in 1- to 1.5-cm intervals, and into endoscopically visible contraction rings. Symptom scores based on an analogue scale for dysphagia, regurgitation, and noncardiac chest pain were assessed before and after therapy, 1 day thereafter, and at 1 and 6 months. Results: Symptoms improved immediately in 7 (78%) patients after 1 injection session. After 4 weeks 8 (89%) patients were in remission with a decrease in total symptom score. The total symptom score decreased from a median 8.0 (interquartile range: 6.75; 9.0) before treatment to 2.0 (1.5; 3.75) after 1 day ( p p Conclusions: BTX injection at several levels of the tubular esophagus is an effective treatment for patients with symptoms caused by Diffuse Esophageal Spasm. Symptom relapse can be effectively treated by repeated BTX injection.