The Experts below are selected from a list of 1512 Experts worldwide ranked by ideXlab platform
Colleen Bamford - One of the best experts on this subject based on the ideXlab platform.
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a Dimorphic fungus causing disseminated Infection in south africa
The New England Journal of Medicine, 2013Co-Authors: Chris Kenyon, Kim Bonorchis, Craig Corcoran, Graeme Meintjes, Michael Locketz, Hester F Vismer, Preneshni Naicker, Hans Prozesky, Marelize Van Wyk, Colleen BamfordAbstract:Background The genus emmonsia contains three species that are associated with human disease. Emmonsia crescens and Emmonsia parva are the agents that cause adiaspiromycosis, and one human case of Emmonsia pasteuriana Infection has been described. We report a Fungal pathogen within the genus emmonsia that is most closely related to E. pasteuriana in human immunodeficiency virus (HIV)–infected adults in South Africa. Methods Between July 2008 and July 2011, we conducted enhanced surveillance to identify the cause of systemic, Dimorphic Fungal Infections in patients presenting to Groote Schuur Hospital and other hospitals affiliated with the University of Cape Town, Cape Town, South Africa. DNA sequencing was used to identify pathogenic fungi. Results A total of 24 cases of Dimorphic Fungal Infection were diagnosed, 13 of which were caused by an emmonsia species. All 13 patients were HIV-infected, with a median CD4+ T-cell count of 16 cells per cubic millimeter (interquartile range, 10 to 44), and all had ev...
Chris Kenyon - One of the best experts on this subject based on the ideXlab platform.
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a Dimorphic fungus causing disseminated Infection in south africa
The New England Journal of Medicine, 2013Co-Authors: Chris Kenyon, Kim Bonorchis, Craig Corcoran, Graeme Meintjes, Michael Locketz, Hester F Vismer, Preneshni Naicker, Hans Prozesky, Marelize Van Wyk, Colleen BamfordAbstract:Background The genus emmonsia contains three species that are associated with human disease. Emmonsia crescens and Emmonsia parva are the agents that cause adiaspiromycosis, and one human case of Emmonsia pasteuriana Infection has been described. We report a Fungal pathogen within the genus emmonsia that is most closely related to E. pasteuriana in human immunodeficiency virus (HIV)–infected adults in South Africa. Methods Between July 2008 and July 2011, we conducted enhanced surveillance to identify the cause of systemic, Dimorphic Fungal Infections in patients presenting to Groote Schuur Hospital and other hospitals affiliated with the University of Cape Town, Cape Town, South Africa. DNA sequencing was used to identify pathogenic fungi. Results A total of 24 cases of Dimorphic Fungal Infection were diagnosed, 13 of which were caused by an emmonsia species. All 13 patients were HIV-infected, with a median CD4+ T-cell count of 16 cells per cubic millimeter (interquartile range, 10 to 44), and all had ev...
G. V. Manjunath - One of the best experts on this subject based on the ideXlab platform.
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Cytodiagnosis of Dimorphic Fungi with Disseminated Infection in a HIV Positive Patient – A Diagnostic Dilemma
2015Co-Authors: Chitresh Yadav, Ini N. M, Shruti M. K, Sowmya G. S, M. R. Shivaprakash, G. V. ManjunathAbstract:Abstract: Systemic mycosis caused by fungi (or Dimorphic fungi) such as Histoplasma, emmonsia, candida & penicillium has emerged as an important opportunistic Fungal Infection in immunocompromised patient in South- East Asia. Several cases of opportunistic Fungal Infection has been reported but cytological diagnosis of disseminated (Dimorphic) Fungal Infection has been reported in very few cases. Cytological diagnosis of these Infections depending on the morphological characteristics has always been a challenge to practising cytologists. A case of rare disseminated Fungal Infection reported in a 45 year old seropositive male who is noncompliant on ART presented with ulcer over palate, fever, weight loss, occasional per rectal bleeding. On examination having bilateral cervical lymphadenopathy and hepatomegaly. On investigation- anaemia, high ESR, deranged liver function test, CD4 count 16/cumm, USG showed hepatomegaly, underwent FNAC cervical lymphnodes and guided FNAC of liver, which showed these organisms, but no pathogens were found with classical microbiological procedure
Kim Bonorchis - One of the best experts on this subject based on the ideXlab platform.
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a Dimorphic fungus causing disseminated Infection in south africa
The New England Journal of Medicine, 2013Co-Authors: Chris Kenyon, Kim Bonorchis, Craig Corcoran, Graeme Meintjes, Michael Locketz, Hester F Vismer, Preneshni Naicker, Hans Prozesky, Marelize Van Wyk, Colleen BamfordAbstract:Background The genus emmonsia contains three species that are associated with human disease. Emmonsia crescens and Emmonsia parva are the agents that cause adiaspiromycosis, and one human case of Emmonsia pasteuriana Infection has been described. We report a Fungal pathogen within the genus emmonsia that is most closely related to E. pasteuriana in human immunodeficiency virus (HIV)–infected adults in South Africa. Methods Between July 2008 and July 2011, we conducted enhanced surveillance to identify the cause of systemic, Dimorphic Fungal Infections in patients presenting to Groote Schuur Hospital and other hospitals affiliated with the University of Cape Town, Cape Town, South Africa. DNA sequencing was used to identify pathogenic fungi. Results A total of 24 cases of Dimorphic Fungal Infection were diagnosed, 13 of which were caused by an emmonsia species. All 13 patients were HIV-infected, with a median CD4+ T-cell count of 16 cells per cubic millimeter (interquartile range, 10 to 44), and all had ev...
Craig Corcoran - One of the best experts on this subject based on the ideXlab platform.
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a Dimorphic fungus causing disseminated Infection in south africa
The New England Journal of Medicine, 2013Co-Authors: Chris Kenyon, Kim Bonorchis, Craig Corcoran, Graeme Meintjes, Michael Locketz, Hester F Vismer, Preneshni Naicker, Hans Prozesky, Marelize Van Wyk, Colleen BamfordAbstract:Background The genus emmonsia contains three species that are associated with human disease. Emmonsia crescens and Emmonsia parva are the agents that cause adiaspiromycosis, and one human case of Emmonsia pasteuriana Infection has been described. We report a Fungal pathogen within the genus emmonsia that is most closely related to E. pasteuriana in human immunodeficiency virus (HIV)–infected adults in South Africa. Methods Between July 2008 and July 2011, we conducted enhanced surveillance to identify the cause of systemic, Dimorphic Fungal Infections in patients presenting to Groote Schuur Hospital and other hospitals affiliated with the University of Cape Town, Cape Town, South Africa. DNA sequencing was used to identify pathogenic fungi. Results A total of 24 cases of Dimorphic Fungal Infection were diagnosed, 13 of which were caused by an emmonsia species. All 13 patients were HIV-infected, with a median CD4+ T-cell count of 16 cells per cubic millimeter (interquartile range, 10 to 44), and all had ev...