The Experts below are selected from a list of 236679 Experts worldwide ranked by ideXlab platform
E Ortizrios - One of the best experts on this subject based on the ideXlab platform.
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donor derived Disease Transmission events in the united states data reviewed by the optn unos Disease Transmission advisory committee
American Journal of Transplantation, 2009Co-Authors: Michael G. Ison, Matthew J. Kuehnert, J. Hager, Emily A. Blumberg, J. Burdick, K. Carney, J. Cutler, J. M. Dimaio, Richard Hasz, E OrtizriosAbstract:Donor-derived Disease Transmission is increasingly recognized as a source of morbidity and mortality among transplant recipients. Policy 4.7 of the Organ Procurement and Transplantation Network (OPTN) currently requires reporting of donor-derived events. All potential donor-derived Transmission events (PDDTE) reported to OPTN/UNOS were reviewed by the Disease Transmission Advisory Committee (DTAC). Summary data from January 1, 2005-December 31, 2007, were prepared for presentation. Reports of PDDTE have increased from 7 in 2005, the first full year data were collected, to 60 in 2006 and to 97 in 2007. More detailed information is available for 2007; a classification system for determining likelihood of donor-derived Transmission was utilized. In 2007, there were four proven and one possible donor-derived malignancy Transmissions and four proven, two probable and six possible donor-derived infectious Diseases Transmissions. There were nine reported recipient deaths attributable to proven donor Transmissions events arising from eight donors during 2007. Although recognized Transmission events resulted in significant morbidity and mortality, Transmission was reported in only 0.96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the Transmission risk of infection and malignancy through organ transplantation.
Matthew J. Kuehnert - One of the best experts on this subject based on the ideXlab platform.
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Infectious Disease Transmission during organ and tissue transplantation
Emerging infectious diseases, 2012Co-Authors: Melissa A. Greenwald, Matthew J. Kuehnert, Jay A. FishmanAbstract:Infectious Disease Transmission through organ and tissue transplantation has been associated with severe complications in recipients. Determination of donor-derived infectious risk associated with organ and tissue transplantation is challenging and limited by availability and performance characteristics of current donor epidemiologic screening (e.g., questionnaire) and laboratory testing tools. Common methods and standards for evaluating potential donors of organs and tissues are needed to facilitate effective data collection for assessing the risk for infectious Disease Transmission. Research programs can use advanced microbiological technologies to define infectious risks posed by pathogens that are known to be transplant transmissible and provide insights into Transmission potential of emerging infectious Diseases for which Transmission characteristics are unknown. Key research needs are explored. Stakeholder collaboration for surveillance and research infrastructure is required to enhance transplant safety.
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donor derived Disease Transmission events in the united states data reviewed by the optn unos Disease Transmission advisory committee
American Journal of Transplantation, 2009Co-Authors: Michael G. Ison, Matthew J. Kuehnert, J. Hager, Emily A. Blumberg, J. Burdick, K. Carney, J. Cutler, J. M. Dimaio, Richard Hasz, E OrtizriosAbstract:Donor-derived Disease Transmission is increasingly recognized as a source of morbidity and mortality among transplant recipients. Policy 4.7 of the Organ Procurement and Transplantation Network (OPTN) currently requires reporting of donor-derived events. All potential donor-derived Transmission events (PDDTE) reported to OPTN/UNOS were reviewed by the Disease Transmission Advisory Committee (DTAC). Summary data from January 1, 2005-December 31, 2007, were prepared for presentation. Reports of PDDTE have increased from 7 in 2005, the first full year data were collected, to 60 in 2006 and to 97 in 2007. More detailed information is available for 2007; a classification system for determining likelihood of donor-derived Transmission was utilized. In 2007, there were four proven and one possible donor-derived malignancy Transmissions and four proven, two probable and six possible donor-derived infectious Diseases Transmissions. There were nine reported recipient deaths attributable to proven donor Transmissions events arising from eight donors during 2007. Although recognized Transmission events resulted in significant morbidity and mortality, Transmission was reported in only 0.96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the Transmission risk of infection and malignancy through organ transplantation.
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Donor-Derived Disease Transmission Events in the United States: Data Reviewed by the OPTN/UNOS Disease Transmission Advisory Committee
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2009Co-Authors: Michael G. Ison, Matthew J. Kuehnert, J. Hager, Emily A. Blumberg, J. Burdick, K. Carney, J. Cutler, J. M. Dimaio, Richard Hasz, E. Ortiz-riosAbstract:Donor-derived Disease Transmission is increasingly recognized as a source of morbidity and mortality among transplant recipients. Policy 4.7 of the Organ Procurement and Transplantation Network (OPTN) currently requires reporting of donor-derived events. All potential donor-derived Transmission events (PDDTE) reported to OPTN/UNOS were reviewed by the Disease Transmission Advisory Committee (DTAC). Summary data from January 1, 2005-December 31, 2007, were prepared for presentation. Reports of PDDTE have increased from 7 in 2005, the first full year data were collected, to 60 in 2006 and to 97 in 2007. More detailed information is available for 2007; a classification system for determining likelihood of donor-derived Transmission was utilized. In 2007, there were four proven and one possible donor-derived malignancy Transmissions and four proven, two probable and six possible donor-derived infectious Diseases Transmissions. There were nine reported recipient deaths attributable to proven donor Transmissions events arising from eight donors during 2007. Although recognized Transmission events resulted in significant morbidity and mortality, Transmission was reported in only 0.96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the Transmission risk of infection and malignancy through organ transplantation.
Michael G. Ison - One of the best experts on this subject based on the ideXlab platform.
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Donor-Derived Disease Transmission in Lung Transplantation
Current Pulmonology Reports, 2020Co-Authors: Scott C Roberts, Michael G. IsonAbstract:Understanding the risk of donor-derived infection, particularly in the lung transplant population, should reduce discarding organs without risk. Ongoing regulatory efforts and improved clinician awareness can help improve organ supply and post-transplantation outcomes. Infections can be divided into expected and unexpected. Syndromes that manifest in the early-post-transplant period should raise concern of a donor-derived Transmission. Emerging data suggests that donors with certain bacterial infections can be safely used while donors with HCV infection can be a useful source of previously discarded organs. Donor-derived Disease Transmission events are rare. Thoughtful donor and recipient screening can mitigate the risk of Disease Transmission through organ transplantation and may identify donor organs that can be safely used.
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An Update on Donor-Derived Disease Transmission in Organ Transplantation
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2011Co-Authors: Michael G. Ison, Michael A. NalesnikAbstract:Several recent donor-to-recipient Disease Transmissions have highlighted the importance of this rare complication of solid organ transplantation. The epidemiology of donor-derived Disease Transmissions in the United States has been described through reports to the Organ Procurement and Transplant Network (OPTN); these reports are reviewed and categorized by the ad hoc Disease Transmission Advisory Committee (DTAC); additional data comes through the published literature. From these reports, it is possible to estimate that donor-derived Disease Transmission complicates less than 1% of all transplant procedures but when a Transmission occurs, significant morbidity and mortality can result. Only through continued presentation of the available data can continuous quality improvements be made. As the epidemiology of donor-derived Disease Transmission has become better understood, several groups have been working on methods to further mitigate this risk.
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donor derived Disease Transmission events in the united states data reviewed by the optn unos Disease Transmission advisory committee
American Journal of Transplantation, 2009Co-Authors: Michael G. Ison, Matthew J. Kuehnert, J. Hager, Emily A. Blumberg, J. Burdick, K. Carney, J. Cutler, J. M. Dimaio, Richard Hasz, E OrtizriosAbstract:Donor-derived Disease Transmission is increasingly recognized as a source of morbidity and mortality among transplant recipients. Policy 4.7 of the Organ Procurement and Transplantation Network (OPTN) currently requires reporting of donor-derived events. All potential donor-derived Transmission events (PDDTE) reported to OPTN/UNOS were reviewed by the Disease Transmission Advisory Committee (DTAC). Summary data from January 1, 2005-December 31, 2007, were prepared for presentation. Reports of PDDTE have increased from 7 in 2005, the first full year data were collected, to 60 in 2006 and to 97 in 2007. More detailed information is available for 2007; a classification system for determining likelihood of donor-derived Transmission was utilized. In 2007, there were four proven and one possible donor-derived malignancy Transmissions and four proven, two probable and six possible donor-derived infectious Diseases Transmissions. There were nine reported recipient deaths attributable to proven donor Transmissions events arising from eight donors during 2007. Although recognized Transmission events resulted in significant morbidity and mortality, Transmission was reported in only 0.96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the Transmission risk of infection and malignancy through organ transplantation.
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Donor-Derived Disease Transmission Events in the United States: Data Reviewed by the OPTN/UNOS Disease Transmission Advisory Committee
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2009Co-Authors: Michael G. Ison, Matthew J. Kuehnert, J. Hager, Emily A. Blumberg, J. Burdick, K. Carney, J. Cutler, J. M. Dimaio, Richard Hasz, E. Ortiz-riosAbstract:Donor-derived Disease Transmission is increasingly recognized as a source of morbidity and mortality among transplant recipients. Policy 4.7 of the Organ Procurement and Transplantation Network (OPTN) currently requires reporting of donor-derived events. All potential donor-derived Transmission events (PDDTE) reported to OPTN/UNOS were reviewed by the Disease Transmission Advisory Committee (DTAC). Summary data from January 1, 2005-December 31, 2007, were prepared for presentation. Reports of PDDTE have increased from 7 in 2005, the first full year data were collected, to 60 in 2006 and to 97 in 2007. More detailed information is available for 2007; a classification system for determining likelihood of donor-derived Transmission was utilized. In 2007, there were four proven and one possible donor-derived malignancy Transmissions and four proven, two probable and six possible donor-derived infectious Diseases Transmissions. There were nine reported recipient deaths attributable to proven donor Transmissions events arising from eight donors during 2007. Although recognized Transmission events resulted in significant morbidity and mortality, Transmission was reported in only 0.96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the Transmission risk of infection and malignancy through organ transplantation.
J. M. Dimaio - One of the best experts on this subject based on the ideXlab platform.
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donor derived Disease Transmission events in the united states data reviewed by the optn unos Disease Transmission advisory committee
American Journal of Transplantation, 2009Co-Authors: Michael G. Ison, Matthew J. Kuehnert, J. Hager, Emily A. Blumberg, J. Burdick, K. Carney, J. Cutler, J. M. Dimaio, Richard Hasz, E OrtizriosAbstract:Donor-derived Disease Transmission is increasingly recognized as a source of morbidity and mortality among transplant recipients. Policy 4.7 of the Organ Procurement and Transplantation Network (OPTN) currently requires reporting of donor-derived events. All potential donor-derived Transmission events (PDDTE) reported to OPTN/UNOS were reviewed by the Disease Transmission Advisory Committee (DTAC). Summary data from January 1, 2005-December 31, 2007, were prepared for presentation. Reports of PDDTE have increased from 7 in 2005, the first full year data were collected, to 60 in 2006 and to 97 in 2007. More detailed information is available for 2007; a classification system for determining likelihood of donor-derived Transmission was utilized. In 2007, there were four proven and one possible donor-derived malignancy Transmissions and four proven, two probable and six possible donor-derived infectious Diseases Transmissions. There were nine reported recipient deaths attributable to proven donor Transmissions events arising from eight donors during 2007. Although recognized Transmission events resulted in significant morbidity and mortality, Transmission was reported in only 0.96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the Transmission risk of infection and malignancy through organ transplantation.
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Donor-Derived Disease Transmission Events in the United States: Data Reviewed by the OPTN/UNOS Disease Transmission Advisory Committee
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2009Co-Authors: Michael G. Ison, Matthew J. Kuehnert, J. Hager, Emily A. Blumberg, J. Burdick, K. Carney, J. Cutler, J. M. Dimaio, Richard Hasz, E. Ortiz-riosAbstract:Donor-derived Disease Transmission is increasingly recognized as a source of morbidity and mortality among transplant recipients. Policy 4.7 of the Organ Procurement and Transplantation Network (OPTN) currently requires reporting of donor-derived events. All potential donor-derived Transmission events (PDDTE) reported to OPTN/UNOS were reviewed by the Disease Transmission Advisory Committee (DTAC). Summary data from January 1, 2005-December 31, 2007, were prepared for presentation. Reports of PDDTE have increased from 7 in 2005, the first full year data were collected, to 60 in 2006 and to 97 in 2007. More detailed information is available for 2007; a classification system for determining likelihood of donor-derived Transmission was utilized. In 2007, there were four proven and one possible donor-derived malignancy Transmissions and four proven, two probable and six possible donor-derived infectious Diseases Transmissions. There were nine reported recipient deaths attributable to proven donor Transmissions events arising from eight donors during 2007. Although recognized Transmission events resulted in significant morbidity and mortality, Transmission was reported in only 0.96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the Transmission risk of infection and malignancy through organ transplantation.
K. Carney - One of the best experts on this subject based on the ideXlab platform.
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donor derived Disease Transmission events in the united states data reviewed by the optn unos Disease Transmission advisory committee
American Journal of Transplantation, 2009Co-Authors: Michael G. Ison, Matthew J. Kuehnert, J. Hager, Emily A. Blumberg, J. Burdick, K. Carney, J. Cutler, J. M. Dimaio, Richard Hasz, E OrtizriosAbstract:Donor-derived Disease Transmission is increasingly recognized as a source of morbidity and mortality among transplant recipients. Policy 4.7 of the Organ Procurement and Transplantation Network (OPTN) currently requires reporting of donor-derived events. All potential donor-derived Transmission events (PDDTE) reported to OPTN/UNOS were reviewed by the Disease Transmission Advisory Committee (DTAC). Summary data from January 1, 2005-December 31, 2007, were prepared for presentation. Reports of PDDTE have increased from 7 in 2005, the first full year data were collected, to 60 in 2006 and to 97 in 2007. More detailed information is available for 2007; a classification system for determining likelihood of donor-derived Transmission was utilized. In 2007, there were four proven and one possible donor-derived malignancy Transmissions and four proven, two probable and six possible donor-derived infectious Diseases Transmissions. There were nine reported recipient deaths attributable to proven donor Transmissions events arising from eight donors during 2007. Although recognized Transmission events resulted in significant morbidity and mortality, Transmission was reported in only 0.96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the Transmission risk of infection and malignancy through organ transplantation.
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Donor-Derived Disease Transmission Events in the United States: Data Reviewed by the OPTN/UNOS Disease Transmission Advisory Committee
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2009Co-Authors: Michael G. Ison, Matthew J. Kuehnert, J. Hager, Emily A. Blumberg, J. Burdick, K. Carney, J. Cutler, J. M. Dimaio, Richard Hasz, E. Ortiz-riosAbstract:Donor-derived Disease Transmission is increasingly recognized as a source of morbidity and mortality among transplant recipients. Policy 4.7 of the Organ Procurement and Transplantation Network (OPTN) currently requires reporting of donor-derived events. All potential donor-derived Transmission events (PDDTE) reported to OPTN/UNOS were reviewed by the Disease Transmission Advisory Committee (DTAC). Summary data from January 1, 2005-December 31, 2007, were prepared for presentation. Reports of PDDTE have increased from 7 in 2005, the first full year data were collected, to 60 in 2006 and to 97 in 2007. More detailed information is available for 2007; a classification system for determining likelihood of donor-derived Transmission was utilized. In 2007, there were four proven and one possible donor-derived malignancy Transmissions and four proven, two probable and six possible donor-derived infectious Diseases Transmissions. There were nine reported recipient deaths attributable to proven donor Transmissions events arising from eight donors during 2007. Although recognized Transmission events resulted in significant morbidity and mortality, Transmission was reported in only 0.96% of deceased donor donations overall. Improved reporting, through enhanced recognition and communication, will be critical to better estimate the Transmission risk of infection and malignancy through organ transplantation.