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Mitsuru Atsuta - One of the best experts on this subject based on the ideXlab platform.

  • adhesive bonding of noble metal alloys with a triazine Dithiol Derivative primer and an adhesive resin
    Journal of Oral Rehabilitation, 1999
    Co-Authors: Yohsuke Taira, Mitsuru Atsuta
    Abstract:

    The purpose of this study was to evaluate the bond strength and durability of a metal adhesive system bonded to noble metal alloys. Disc specimens were cast from type IV gold (type IV, Casting Gold M.C.®), metal–ceramic gold (Au–Pt–Pd, Degudent Universal®), metal–ceramic palladium (Pd–Ga–Co, PTM 88®), silver–indium (Ag–In–Zn, Salivan Hard®) and silver–palladium–copper–gold (Ag–Pd–Cu, S12®) alloys and pure silver (pure Ag). The specimens were air-abraded with 50 μm alumina, conditioned with a thiol-based primer designed for noble alloys (V-Primer®), and then bonded with an adhesive resin (Super-Bond Opaque Ivory®). Shear bond strengths were determined after repeated thermocycling (4–60 °C, 1 min each, 100 000 cycles). The average bond strengths in MPa (n=8) were 30·9 for the type IV alloy, 29·0 for the Ag–Pd–Cu alloy, 28·0 for the Au–Pt–Pd alloy, 26·3 for the pure Ag, 26·0 for the Pd–Ga–Co alloy and 9·3 for the Ag–In–Zn alloy. The Ag–In–Zn alloy exhibited significantly lower bond strength than the other alloys, whereas the bond strengths of the other four alloys and pure Ag were comparable (P<0·05). It is concluded that the combined use of the thiol Derivative primer and the adhesive resin is effective for bonding the noble metal alloys examined, with the exception of the Ag–In–Zn alloy.

  • adhesive bonding of noble metal alloys with a triazine Dithiol Derivative primer and an adhesive resin
    Journal of Oral Rehabilitation, 1999
    Co-Authors: Hideo Matsumura, Yohsuke Taira, Mitsuru Atsuta
    Abstract:

    : The purpose of this study was to evaluate the bond strength and durability of a metal adhesive system bonded to noble metal alloys. Disc specimens were cast from type IV gold (type IV, Casting Gold M. C., metal-ceramic gold (Au-Pt-Pd, Degudent Universal, metal-ceramic palladium (Pd-Ga-Co, PTM 88 silver-indium (Ag-In-Zn, Salivan Hard and silver-palladium-copper-gold (Ag-Pd-Cu, S12) alloys and pure silver (pure Ag). The specimens were air-abraded with 50 micron alumina, conditioned with a thiol-based primer designed for noble alloys (V-Primer), and then bonded with an adhesive resin (Super-Bond Opaque Ivory). Shear bond strengths were determined after repeated thermocycling (4-60 degrees C, 1 min each, 100 000 cycles). The average bond strengths in MPa (n=8) were 30.9 for the type IV alloy, 29.0 for the Ag-Pd-Cu alloy, 28.0 for the Au-Pt-Pd alloy, 26.3 for the pure Ag, 26.0 for the Pd-Ga-Co alloy and 9.3 for the Ag-In-Zn alloy. The Ag-In-Zn alloy exhibited significantly lower bond strength than the other alloys, whereas the bond strengths of the other four alloys and pure Ag were comparable (P<0.05). It is concluded that the combined use of the thiol Derivative primer and the adhesive resin is effective for bonding the noble metal alloys examined, with the exception of the Ag-In-Zn alloy.

  • Adhesive bonding of noble metal alloys with a triazine Dithiol Derivative primer and an adhesive resin.
    Journal of Oral Rehabilitation, 1999
    Co-Authors: Hideo Matsumura, Yohsuke Taira, Mitsuru Atsuta
    Abstract:

    The purpose of this study was to evaluate the bond strength and durability of a metal adhesive system bonded to noble metal alloys. Disc specimens were cast from type IV gold (type IV, Casting Gold M. C., metal-ceramic gold (Au-Pt-Pd, Degudent Universal, metal-ceramic palladium (Pd-Ga-Co, PTM 88 silver-indium (Ag-In-Zn, Salivan Hard and silver-palladium-copper-gold (Ag-Pd-Cu, S12) alloys and pure silver (pure Ag). The specimens were air-abraded with 50 micron alumina, conditioned with a thiol-based primer designed for noble alloys (V-Primer), and then bonded with an adhesive resin (Super-Bond Opaque Ivory). Shear bond strengths were determined after repeated thermocycling (4-60 degrees C, 1 min each, 100 000 cycles). The average bond strengths in MPa (n=8) were 30.9 for the type IV alloy, 29.0 for the Ag-Pd-Cu alloy, 28.0 for the Au-Pt-Pd alloy, 26.3 for the pure Ag, 26.0 for the Pd-Ga-Co alloy and 9.3 for the Ag-In-Zn alloy. The Ag-In-Zn alloy exhibited significantly lower bond strength than the other alloys, whereas the bond strengths of the other four alloys and pure Ag were comparable (P

Yohsuke Taira - One of the best experts on this subject based on the ideXlab platform.

  • adhesive bonding of noble metal alloys with a triazine Dithiol Derivative primer and an adhesive resin
    Journal of Oral Rehabilitation, 1999
    Co-Authors: Yohsuke Taira, Mitsuru Atsuta
    Abstract:

    The purpose of this study was to evaluate the bond strength and durability of a metal adhesive system bonded to noble metal alloys. Disc specimens were cast from type IV gold (type IV, Casting Gold M.C.®), metal–ceramic gold (Au–Pt–Pd, Degudent Universal®), metal–ceramic palladium (Pd–Ga–Co, PTM 88®), silver–indium (Ag–In–Zn, Salivan Hard®) and silver–palladium–copper–gold (Ag–Pd–Cu, S12®) alloys and pure silver (pure Ag). The specimens were air-abraded with 50 μm alumina, conditioned with a thiol-based primer designed for noble alloys (V-Primer®), and then bonded with an adhesive resin (Super-Bond Opaque Ivory®). Shear bond strengths were determined after repeated thermocycling (4–60 °C, 1 min each, 100 000 cycles). The average bond strengths in MPa (n=8) were 30·9 for the type IV alloy, 29·0 for the Ag–Pd–Cu alloy, 28·0 for the Au–Pt–Pd alloy, 26·3 for the pure Ag, 26·0 for the Pd–Ga–Co alloy and 9·3 for the Ag–In–Zn alloy. The Ag–In–Zn alloy exhibited significantly lower bond strength than the other alloys, whereas the bond strengths of the other four alloys and pure Ag were comparable (P<0·05). It is concluded that the combined use of the thiol Derivative primer and the adhesive resin is effective for bonding the noble metal alloys examined, with the exception of the Ag–In–Zn alloy.

  • adhesive bonding of noble metal alloys with a triazine Dithiol Derivative primer and an adhesive resin
    Journal of Oral Rehabilitation, 1999
    Co-Authors: Hideo Matsumura, Yohsuke Taira, Mitsuru Atsuta
    Abstract:

    : The purpose of this study was to evaluate the bond strength and durability of a metal adhesive system bonded to noble metal alloys. Disc specimens were cast from type IV gold (type IV, Casting Gold M. C., metal-ceramic gold (Au-Pt-Pd, Degudent Universal, metal-ceramic palladium (Pd-Ga-Co, PTM 88 silver-indium (Ag-In-Zn, Salivan Hard and silver-palladium-copper-gold (Ag-Pd-Cu, S12) alloys and pure silver (pure Ag). The specimens were air-abraded with 50 micron alumina, conditioned with a thiol-based primer designed for noble alloys (V-Primer), and then bonded with an adhesive resin (Super-Bond Opaque Ivory). Shear bond strengths were determined after repeated thermocycling (4-60 degrees C, 1 min each, 100 000 cycles). The average bond strengths in MPa (n=8) were 30.9 for the type IV alloy, 29.0 for the Ag-Pd-Cu alloy, 28.0 for the Au-Pt-Pd alloy, 26.3 for the pure Ag, 26.0 for the Pd-Ga-Co alloy and 9.3 for the Ag-In-Zn alloy. The Ag-In-Zn alloy exhibited significantly lower bond strength than the other alloys, whereas the bond strengths of the other four alloys and pure Ag were comparable (P<0.05). It is concluded that the combined use of the thiol Derivative primer and the adhesive resin is effective for bonding the noble metal alloys examined, with the exception of the Ag-In-Zn alloy.

  • Adhesive bonding of noble metal alloys with a triazine Dithiol Derivative primer and an adhesive resin.
    Journal of Oral Rehabilitation, 1999
    Co-Authors: Hideo Matsumura, Yohsuke Taira, Mitsuru Atsuta
    Abstract:

    The purpose of this study was to evaluate the bond strength and durability of a metal adhesive system bonded to noble metal alloys. Disc specimens were cast from type IV gold (type IV, Casting Gold M. C., metal-ceramic gold (Au-Pt-Pd, Degudent Universal, metal-ceramic palladium (Pd-Ga-Co, PTM 88 silver-indium (Ag-In-Zn, Salivan Hard and silver-palladium-copper-gold (Ag-Pd-Cu, S12) alloys and pure silver (pure Ag). The specimens were air-abraded with 50 micron alumina, conditioned with a thiol-based primer designed for noble alloys (V-Primer), and then bonded with an adhesive resin (Super-Bond Opaque Ivory). Shear bond strengths were determined after repeated thermocycling (4-60 degrees C, 1 min each, 100 000 cycles). The average bond strengths in MPa (n=8) were 30.9 for the type IV alloy, 29.0 for the Ag-Pd-Cu alloy, 28.0 for the Au-Pt-Pd alloy, 26.3 for the pure Ag, 26.0 for the Pd-Ga-Co alloy and 9.3 for the Ag-In-Zn alloy. The Ag-In-Zn alloy exhibited significantly lower bond strength than the other alloys, whereas the bond strengths of the other four alloys and pure Ag were comparable (P

Hideo Matsumura - One of the best experts on this subject based on the ideXlab platform.

  • adhesive bonding of noble metal alloys with a triazine Dithiol Derivative primer and an adhesive resin
    Journal of Oral Rehabilitation, 1999
    Co-Authors: Hideo Matsumura, Yohsuke Taira, Mitsuru Atsuta
    Abstract:

    : The purpose of this study was to evaluate the bond strength and durability of a metal adhesive system bonded to noble metal alloys. Disc specimens were cast from type IV gold (type IV, Casting Gold M. C., metal-ceramic gold (Au-Pt-Pd, Degudent Universal, metal-ceramic palladium (Pd-Ga-Co, PTM 88 silver-indium (Ag-In-Zn, Salivan Hard and silver-palladium-copper-gold (Ag-Pd-Cu, S12) alloys and pure silver (pure Ag). The specimens were air-abraded with 50 micron alumina, conditioned with a thiol-based primer designed for noble alloys (V-Primer), and then bonded with an adhesive resin (Super-Bond Opaque Ivory). Shear bond strengths were determined after repeated thermocycling (4-60 degrees C, 1 min each, 100 000 cycles). The average bond strengths in MPa (n=8) were 30.9 for the type IV alloy, 29.0 for the Ag-Pd-Cu alloy, 28.0 for the Au-Pt-Pd alloy, 26.3 for the pure Ag, 26.0 for the Pd-Ga-Co alloy and 9.3 for the Ag-In-Zn alloy. The Ag-In-Zn alloy exhibited significantly lower bond strength than the other alloys, whereas the bond strengths of the other four alloys and pure Ag were comparable (P<0.05). It is concluded that the combined use of the thiol Derivative primer and the adhesive resin is effective for bonding the noble metal alloys examined, with the exception of the Ag-In-Zn alloy.

  • Adhesive bonding of noble metal alloys with a triazine Dithiol Derivative primer and an adhesive resin.
    Journal of Oral Rehabilitation, 1999
    Co-Authors: Hideo Matsumura, Yohsuke Taira, Mitsuru Atsuta
    Abstract:

    The purpose of this study was to evaluate the bond strength and durability of a metal adhesive system bonded to noble metal alloys. Disc specimens were cast from type IV gold (type IV, Casting Gold M. C., metal-ceramic gold (Au-Pt-Pd, Degudent Universal, metal-ceramic palladium (Pd-Ga-Co, PTM 88 silver-indium (Ag-In-Zn, Salivan Hard and silver-palladium-copper-gold (Ag-Pd-Cu, S12) alloys and pure silver (pure Ag). The specimens were air-abraded with 50 micron alumina, conditioned with a thiol-based primer designed for noble alloys (V-Primer), and then bonded with an adhesive resin (Super-Bond Opaque Ivory). Shear bond strengths were determined after repeated thermocycling (4-60 degrees C, 1 min each, 100 000 cycles). The average bond strengths in MPa (n=8) were 30.9 for the type IV alloy, 29.0 for the Ag-Pd-Cu alloy, 28.0 for the Au-Pt-Pd alloy, 26.3 for the pure Ag, 26.0 for the Pd-Ga-Co alloy and 9.3 for the Ag-In-Zn alloy. The Ag-In-Zn alloy exhibited significantly lower bond strength than the other alloys, whereas the bond strengths of the other four alloys and pure Ag were comparable (P

Shohko Tsunawaki - One of the best experts on this subject based on the ideXlab platform.

  • fungal gliotoxin targets the onset of superoxide generating nadph oxidase of human neutrophils
    Biochemical and Biophysical Research Communications, 2000
    Co-Authors: Lucia S Yoshida, Shigeru Abe, Shohko Tsunawaki
    Abstract:

    Abstract Gliotoxin from Aspergillus, bearing a SS bond in its structure, prevented the onset of O − 2 generation by the human neutrophil NADPH oxidase in response to phorbol myristate acetate (PMA). Gliotoxin affected the activation process harder than the activated oxidase, as shown by its stronger inhibition when added to neutrophils prior to, than post-PMA at maximum enzyme turnover. Decreased O − 2 generation persisted even if cells treated with gliotoxin were subsequently washed, with half-inhibition concentrations (IC 50 ) of 5.3, and 3.5 μM for treatments of 15 and 30 min, respectively. In addition, gliotoxin made neutrophils reduce cytochrome c regardless of absence of PMA, through its reaction with intracellular reductants in an oxygen-dependent process, named redox cycling. Thus, we next tested whether preincubation of neutrophils with gliotoxin under hypoxic conditions would relieve the inhibition of NADPH oxidase. Instead, this prevention of redox cycling significantly favored damage to the NADPH oxidase with an IC 50 of 0.009 μM. Moreover, conversion of gliotoxin to its Dithiol Derivative by addition of reduced dithiothreitol during incubation protected cells from losing oxidase activity. These findings support that the disulfide form of gliotoxin targets NADPH oxidase activation.

Lucia S Yoshida - One of the best experts on this subject based on the ideXlab platform.

  • fungal gliotoxin targets the onset of superoxide generating nadph oxidase of human neutrophils
    Biochemical and Biophysical Research Communications, 2000
    Co-Authors: Lucia S Yoshida, Shigeru Abe, Shohko Tsunawaki
    Abstract:

    Abstract Gliotoxin from Aspergillus, bearing a SS bond in its structure, prevented the onset of O − 2 generation by the human neutrophil NADPH oxidase in response to phorbol myristate acetate (PMA). Gliotoxin affected the activation process harder than the activated oxidase, as shown by its stronger inhibition when added to neutrophils prior to, than post-PMA at maximum enzyme turnover. Decreased O − 2 generation persisted even if cells treated with gliotoxin were subsequently washed, with half-inhibition concentrations (IC 50 ) of 5.3, and 3.5 μM for treatments of 15 and 30 min, respectively. In addition, gliotoxin made neutrophils reduce cytochrome c regardless of absence of PMA, through its reaction with intracellular reductants in an oxygen-dependent process, named redox cycling. Thus, we next tested whether preincubation of neutrophils with gliotoxin under hypoxic conditions would relieve the inhibition of NADPH oxidase. Instead, this prevention of redox cycling significantly favored damage to the NADPH oxidase with an IC 50 of 0.009 μM. Moreover, conversion of gliotoxin to its Dithiol Derivative by addition of reduced dithiothreitol during incubation protected cells from losing oxidase activity. These findings support that the disulfide form of gliotoxin targets NADPH oxidase activation.