The Experts below are selected from a list of 18 Experts worldwide ranked by ideXlab platform
Rojo Javier - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of dimeric aryl b-D-galactopyranosides for the evaluation of their interaction with the Erythrina cristagalli lectin.
2009Co-Authors: Figueiredo,rute Cunha, Meyer,nádia Burkowski, Prado,maria Auxiliadôra Fontes, Rojo JavierAbstract:The synthesis of two new D-galactose-based dimers having a 1,4-butanediamine spacer is reported aiming at the evaluation of their interaction with the Erythrina cristagalli lectin. The title compounds were prepared in four and five steps from 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside bromide, in 20 % and 15 % overall yield, respectively, using the Doebner Modification of the Koenavenagel reaction as the key sep. The lectin-carbohydrate interaction could be evaluated for only one dimer, due to solubility problems. A twofold enhancement of affinity was observed, compared to the corresponding monovalent ligand
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Synthesis of dimeric aryl β-D-galactopyranosides for the evaluation of their interaction with the Erythrina cristagalli lectin
'FapUNIFESP (SciELO)', 2009Co-Authors: Cunha Figueiredo Rute, Alves,ricardo José, Burkowski Meyer Nádia, Fontes Prado, María Auxiliadora, Rojo JavierAbstract:5 páginas, 2 figuras, 1 tabla.The synthesis of two new D-galactose-based dimers having a 1,4-butanediamine spacer is reported aiming at the evaluation of their interaction with the Erythrina cristagalli lectin. The title compounds were prepared in four and five steps from 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside bromide, in 20 % and 15 % overall yield, respectively, using the Doebner Modification of the Koenavenagel reaction as the key sep. The lectin-carbohydrate interaction could be evaluated for only one dimer, due to solubility problems. A twofold enhancement of affinity was observed, compared to the corresponding monovalent ligand.Ao CNPq, CAPES e FAPEMIG a concessão de auxílio financeiro, bolsa de doutorado (R. C. Figueiredo) e bolsa de produtividade (M. A. F. Prado e R. J. Alves).Peer reviewe
Alves,ricardo José - One of the best experts on this subject based on the ideXlab platform.
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Síntese de β-D-galactopiranosídeos de arila diméricos para avaliação de sua interação com a lectina de Erythrina cristagalli
Sociedade Brasileira de Química, 2009Co-Authors: Figueiredo,rute Cunha, Meyer,nádia Burkowski, Prado,maria Auxiliadôra Fontes, Alves,ricardo JoséAbstract:The synthesis of two new D-galactose-based dimers having a 1,4-butanediamine spacer is reported aiming at the evaluation of their interaction with the Erythrina cristagalli lectin. The title compounds were prepared in four and five steps from 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside bromide, in 20 % and 15 % overall yield, respectively, using the Doebner Modification of the Koenavenagel reaction as the key sep. The lectin-carbohydrate interaction could be evaluated for only one dimer, due to solubility problems. A twofold enhancement of affinity was observed, compared to the corresponding monovalent ligand
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Synthesis of dimeric aryl β-D-galactopyranosides for the evaluation of their interaction with the Erythrina cristagalli lectin
'FapUNIFESP (SciELO)', 2009Co-Authors: Cunha Figueiredo Rute, Alves,ricardo José, Burkowski Meyer Nádia, Fontes Prado, María Auxiliadora, Rojo JavierAbstract:5 páginas, 2 figuras, 1 tabla.The synthesis of two new D-galactose-based dimers having a 1,4-butanediamine spacer is reported aiming at the evaluation of their interaction with the Erythrina cristagalli lectin. The title compounds were prepared in four and five steps from 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside bromide, in 20 % and 15 % overall yield, respectively, using the Doebner Modification of the Koenavenagel reaction as the key sep. The lectin-carbohydrate interaction could be evaluated for only one dimer, due to solubility problems. A twofold enhancement of affinity was observed, compared to the corresponding monovalent ligand.Ao CNPq, CAPES e FAPEMIG a concessão de auxílio financeiro, bolsa de doutorado (R. C. Figueiredo) e bolsa de produtividade (M. A. F. Prado e R. J. Alves).Peer reviewe
Figueiredo,rute Cunha - One of the best experts on this subject based on the ideXlab platform.
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Síntese de β-D-galactopiranosídeos de arila diméricos para avaliação de sua interação com a lectina de Erythrina cristagalli
Sociedade Brasileira de Química, 2009Co-Authors: Figueiredo,rute Cunha, Meyer,nádia Burkowski, Prado,maria Auxiliadôra Fontes, Alves,ricardo JoséAbstract:The synthesis of two new D-galactose-based dimers having a 1,4-butanediamine spacer is reported aiming at the evaluation of their interaction with the Erythrina cristagalli lectin. The title compounds were prepared in four and five steps from 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside bromide, in 20 % and 15 % overall yield, respectively, using the Doebner Modification of the Koenavenagel reaction as the key sep. The lectin-carbohydrate interaction could be evaluated for only one dimer, due to solubility problems. A twofold enhancement of affinity was observed, compared to the corresponding monovalent ligand
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Synthesis of dimeric aryl b-D-galactopyranosides for the evaluation of their interaction with the Erythrina cristagalli lectin.
2009Co-Authors: Figueiredo,rute Cunha, Meyer,nádia Burkowski, Prado,maria Auxiliadôra Fontes, Rojo JavierAbstract:The synthesis of two new D-galactose-based dimers having a 1,4-butanediamine spacer is reported aiming at the evaluation of their interaction with the Erythrina cristagalli lectin. The title compounds were prepared in four and five steps from 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside bromide, in 20 % and 15 % overall yield, respectively, using the Doebner Modification of the Koenavenagel reaction as the key sep. The lectin-carbohydrate interaction could be evaluated for only one dimer, due to solubility problems. A twofold enhancement of affinity was observed, compared to the corresponding monovalent ligand
Cunha Figueiredo Rute - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of dimeric aryl β-D-galactopyranosides for the evaluation of their interaction with the Erythrina cristagalli lectin
'FapUNIFESP (SciELO)', 2009Co-Authors: Cunha Figueiredo Rute, Alves,ricardo José, Burkowski Meyer Nádia, Fontes Prado, María Auxiliadora, Rojo JavierAbstract:5 páginas, 2 figuras, 1 tabla.The synthesis of two new D-galactose-based dimers having a 1,4-butanediamine spacer is reported aiming at the evaluation of their interaction with the Erythrina cristagalli lectin. The title compounds were prepared in four and five steps from 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside bromide, in 20 % and 15 % overall yield, respectively, using the Doebner Modification of the Koenavenagel reaction as the key sep. The lectin-carbohydrate interaction could be evaluated for only one dimer, due to solubility problems. A twofold enhancement of affinity was observed, compared to the corresponding monovalent ligand.Ao CNPq, CAPES e FAPEMIG a concessão de auxílio financeiro, bolsa de doutorado (R. C. Figueiredo) e bolsa de produtividade (M. A. F. Prado e R. J. Alves).Peer reviewe
Meyer,nádia Burkowski - One of the best experts on this subject based on the ideXlab platform.
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Síntese de β-D-galactopiranosídeos de arila diméricos para avaliação de sua interação com a lectina de Erythrina cristagalli
Sociedade Brasileira de Química, 2009Co-Authors: Figueiredo,rute Cunha, Meyer,nádia Burkowski, Prado,maria Auxiliadôra Fontes, Alves,ricardo JoséAbstract:The synthesis of two new D-galactose-based dimers having a 1,4-butanediamine spacer is reported aiming at the evaluation of their interaction with the Erythrina cristagalli lectin. The title compounds were prepared in four and five steps from 2,3,4,6-tetra-O-acetyl-β-D-galactopyranoside bromide, in 20 % and 15 % overall yield, respectively, using the Doebner Modification of the Koenavenagel reaction as the key sep. The lectin-carbohydrate interaction could be evaluated for only one dimer, due to solubility problems. A twofold enhancement of affinity was observed, compared to the corresponding monovalent ligand
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Synthesis of dimeric aryl b-D-galactopyranosides for the evaluation of their interaction with the Erythrina cristagalli lectin.
2009Co-Authors: Figueiredo,rute Cunha, Meyer,nádia Burkowski, Prado,maria Auxiliadôra Fontes, Rojo JavierAbstract:The synthesis of two new D-galactose-based dimers having a 1,4-butanediamine spacer is reported aiming at the evaluation of their interaction with the Erythrina cristagalli lectin. The title compounds were prepared in four and five steps from 2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside bromide, in 20 % and 15 % overall yield, respectively, using the Doebner Modification of the Koenavenagel reaction as the key sep. The lectin-carbohydrate interaction could be evaluated for only one dimer, due to solubility problems. A twofold enhancement of affinity was observed, compared to the corresponding monovalent ligand