The Experts below are selected from a list of 18 Experts worldwide ranked by ideXlab platform
David W. Lupton - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of Spirocyclic γ-Lactones by Cascade Beckwith–Dowd Ring Expansion/Cyclization
2016Co-Authors: Judith Hierold, David W. LuptonAbstract:A range of spirocyclic γ-lactones have been prepared exploiting a Beckwith–Dowd Ring Expansion cascade involving 1-, 3-, 4-, and 5-carbon Expansion of cyclopentanone and cyclohexanone followed by 5-exo-trig or 5-exo-dig cyclization. This radical cascade reaction can be achieved with various substrates to provide a broad range of γ-lactones spirofused to 6- to 10-membered cycloalkanones
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synthesis of spirocyclic γ lactones by cascade beckwith Dowd Ring Expansion cyclization
Organic Letters, 2012Co-Authors: Judith Hierold, David W. LuptonAbstract:A range of spirocyclic γ-lactones have been prepared exploiting a Beckwith–Dowd Ring Expansion cascade involving 1-, 3-, 4-, and 5-carbon Expansion of cyclopentanone and cyclohexanone followed by 5-exo-trig or 5-exo-dig cyclization. This radical cascade reaction can be achieved with various substrates to provide a broad range of γ-lactones spirofused to 6- to 10-membered cycloalkanones.
Hanfeng Ding - One of the best experts on this subject based on the ideXlab platform.
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Diastereoselective Total Synthesis of Salvileucalin C
Organic Letters, 2014Co-Authors: Chenchen Fu, Y.h. Zhang, Jun Xuan, Bingnan Wang, Hanfeng DingAbstract:A concise and efficient approach for the diastereoselective total synthesis of salvileucalin C, as well as their biosynthetically related diterpenoids salvileucalin D, salvipuberulin, isosalvipuberulin, and dugesin B, has been reported for the first time. The key features of the strategy are based on a Beckwith–Dowd Ring Expansion, a tandem diastereoselective Stille coupling/debromination/desilylation/lactonization reaction, and a photoinduced electrocyclic Ring contraction.
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Diastereoselective Total Synthesis of Salvileucalin C
2014Co-Authors: Yuanbao Zhang, Jun Xuan, Bingnan Wang, Chenlong Zhu, Hanfeng DingAbstract:A concise and efficient approach for the diastereoselective total synthesis of salvileucalin C, as well as their biosynthetically related diterpenoids salvileucalin D, salvipuberulin, isosalvipuberulin, and dugesin B, has been reported for the first time. The key features of the strategy are based on a Beckwith–Dowd Ring Expansion, a tandem diastereoselective Stille coupling/debromination/desilylation/lactonization reaction, and a photoinduced electrocyclic Ring contraction
Judith Hierold - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of Spirocyclic γ-Lactones by Cascade Beckwith–Dowd Ring Expansion/Cyclization
2016Co-Authors: Judith Hierold, David W. LuptonAbstract:A range of spirocyclic γ-lactones have been prepared exploiting a Beckwith–Dowd Ring Expansion cascade involving 1-, 3-, 4-, and 5-carbon Expansion of cyclopentanone and cyclohexanone followed by 5-exo-trig or 5-exo-dig cyclization. This radical cascade reaction can be achieved with various substrates to provide a broad range of γ-lactones spirofused to 6- to 10-membered cycloalkanones
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synthesis of spirocyclic γ lactones by cascade beckwith Dowd Ring Expansion cyclization
Organic Letters, 2012Co-Authors: Judith Hierold, David W. LuptonAbstract:A range of spirocyclic γ-lactones have been prepared exploiting a Beckwith–Dowd Ring Expansion cascade involving 1-, 3-, 4-, and 5-carbon Expansion of cyclopentanone and cyclohexanone followed by 5-exo-trig or 5-exo-dig cyclization. This radical cascade reaction can be achieved with various substrates to provide a broad range of γ-lactones spirofused to 6- to 10-membered cycloalkanones.
Chenchen Fu - One of the best experts on this subject based on the ideXlab platform.
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Diastereoselective Total Synthesis of Salvileucalin C
Organic Letters, 2014Co-Authors: Chenchen Fu, Y.h. Zhang, Jun Xuan, Bingnan Wang, Hanfeng DingAbstract:A concise and efficient approach for the diastereoselective total synthesis of salvileucalin C, as well as their biosynthetically related diterpenoids salvileucalin D, salvipuberulin, isosalvipuberulin, and dugesin B, has been reported for the first time. The key features of the strategy are based on a Beckwith–Dowd Ring Expansion, a tandem diastereoselective Stille coupling/debromination/desilylation/lactonization reaction, and a photoinduced electrocyclic Ring contraction.
Jun Xuan - One of the best experts on this subject based on the ideXlab platform.
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Diastereoselective Total Synthesis of Salvileucalin C
Organic Letters, 2014Co-Authors: Chenchen Fu, Y.h. Zhang, Jun Xuan, Bingnan Wang, Hanfeng DingAbstract:A concise and efficient approach for the diastereoselective total synthesis of salvileucalin C, as well as their biosynthetically related diterpenoids salvileucalin D, salvipuberulin, isosalvipuberulin, and dugesin B, has been reported for the first time. The key features of the strategy are based on a Beckwith–Dowd Ring Expansion, a tandem diastereoselective Stille coupling/debromination/desilylation/lactonization reaction, and a photoinduced electrocyclic Ring contraction.
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Diastereoselective Total Synthesis of Salvileucalin C
2014Co-Authors: Yuanbao Zhang, Jun Xuan, Bingnan Wang, Chenlong Zhu, Hanfeng DingAbstract:A concise and efficient approach for the diastereoselective total synthesis of salvileucalin C, as well as their biosynthetically related diterpenoids salvileucalin D, salvipuberulin, isosalvipuberulin, and dugesin B, has been reported for the first time. The key features of the strategy are based on a Beckwith–Dowd Ring Expansion, a tandem diastereoselective Stille coupling/debromination/desilylation/lactonization reaction, and a photoinduced electrocyclic Ring contraction