The Experts below are selected from a list of 160701 Experts worldwide ranked by ideXlab platform
Pere Rafols - One of the best experts on this subject based on the ideXlab platform.
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rmsicleanup an open source tool for matrix related peak annotation in mass spectrometry imaging and its application to silver assisted laser desorption ionization
Journal of Cheminformatics, 2020Co-Authors: Gerard Baquer, Lluc Semente, Maria Garciaaltares, Young Jin Lee, Pierre Chaurand, X Correig, Pere RafolsAbstract:Mass spectrometry imaging (MSI) has become a mature, widespread analytical technique to perform non-targeted spatial metabolomics. However, the compounds used to promote desorption and ionization of the analyte during acquisition cause spectral interferences in the low mass range that hinder Downstream Data processing in metabolomics applications. Thus, it is advisable to annotate and remove matrix-related peaks to reduce the number of redundant and non-biologically-relevant variables in the Dataset. We have developed rMSIcleanup, an open-source R package to annotate and remove signals from the matrix, according to the matrix chemical composition and the spatial distribution of its ions. To validate the annotation method, rMSIcleanup was challenged with several images acquired using silver-assisted laser desorption ionization MSI (AgLDI MSI). The algorithm was able to correctly classify m/z signals related to silver clusters. Visual exploration of the Data using Principal Component Analysis (PCA) demonstrated that annotation and removal of matrix-related signals improved spectral Data post-processing. The results highlight the need for including matrix-related peak annotation tools such as rMSIcleanup in MSI workflows.
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rmsicleanup an open source tool for matrix related peak annotation in mass spectrometry imaging and its application to silver assisted laser desorption ionization
bioRxiv, 2019Co-Authors: Gerard Baquer, Lluc Semente, Maria Garciaaltares, Young Jin Lee, Pierre Chaurand, X Correig, Pere RafolsAbstract:Abstract Mass spectrometry imaging (MSI) has become a mature, widespread analytical technique to perform non-targeted spatial metabolomics. However, the compounds used to promote desorption and ionization of the analyte during acquisition cause spectral interferences in the low mass range that hinder Downstream Data processing in metabolomics applications. Thus, it is advisable to annotate and remove matrix-related peaks to reduce the number of redundant and non-biologically-relevant variables in the Dataset. We have developed rMSIcleanup, an open-source R package to annotate and remove matrix-related signals based on its chemical formula and the spatial distribution of its ions. To validate the annotation method, rMSIcleanup was challenged with several images acquired using silver-assisted laser desorption ionization MSI (AgLDI MSI). The algorithm was able to correctly classify m/z signals related to silver clusters. Visual exploration of the Data using Principal Component Analysis (PCA) demonstrated that annotation and removal of matrix-related signals improved spectral Data post-processing. The results highlight the need for including matrix-related peak annotation tools such as rMSIcleanup in MSI workflows. Resources availability The R package presented in this publication is freely available under the terms of the GNU General Public License v3.0 at https://github.com/gbaquer/rMSIcleanup. The Datasets used in the experiments can be accessed upon request to the corresponding author.
Rabah Attia - One of the best experts on this subject based on the ideXlab platform.
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bidirectional long reach wdm pon delivering Downstream Data 20 gbps and upstream Data 10 gbps using mode locked laser and rsoa
Optical and Quantum Electronics, 2015Co-Authors: Laxman Tawade, Sofien Mhatli, Rabah AttiaAbstract:This paper presents long reach wavelength division multiplexing passive optical network (WDM-PON) system capable of delivering Downstream 20 Gbit/s Data and upstream 10 Gbit/s Data on a single wavelength. The optical source for Downstream Data and upstream Data is mode locked laser at central office and reflective semiconductor optical amplifier (RSOA) at each optical network unit. We use two RSOAs at each optical network unit for the 10-Gb/s upstream transmission. The operating wavelengths of these RSOAs are separated by the free-spectral range of the cyclic arrayed waveguide gratings used at the central office and remote node (RN) for (de)multiplexing the WDM channels. We extend the maximum reach of this WDM PON to be 45 km by using Erbium-doped fiber amplifiers at the RN.The hybrid amplifier is designed to enhance the signal power and compensated the fiber dispersion over a wide wavelength range. Optical Equalization technique is used before the receiver to improve modulation bandwidth of an RSOA based colorless optical network unit. Optical Equalization technique helps to improve downlink and uplink performance. Author also investigates analysis of backscattered optical signal for upstream Data and Downstream Data simultaneously. Bit error rate, backscattered optical signal power were measured to demonstrate the proposed scheme. In this paper Long reach and large Data service aspects of a WDM-PON is presented.
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long reach ofdm wdm pon delivering 100 gb s of Data Downstream and 2 gb s of Data upstream using a continuous wave laser and a reflective semiconductor optical amplifier
Optics Letters, 2014Co-Authors: Sofien Mhatli, Laxman Tawade, Mohammad Ghanbarisabagh, Bechir Nsiri, Mutsam A Jarajreh, Malak Channoufi, Rabah AttiaAbstract:This paper presents a long-reach orthogonal frequency division multiplexing wavelength division multiplexing passive optical network (OFDM WDM–PON), a system capable of delivering 100 Gb/s of Data Downstream and 2 Gb/s of Data upstream on a single wavelength. The optical sources for Downstream Data and upstream Data are a continuous-wave laser at a central office and a reflective semiconductor optical amplifier (RSOA) at each optical network unit.
Gerard Baquer - One of the best experts on this subject based on the ideXlab platform.
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rmsicleanup an open source tool for matrix related peak annotation in mass spectrometry imaging and its application to silver assisted laser desorption ionization
Journal of Cheminformatics, 2020Co-Authors: Gerard Baquer, Lluc Semente, Maria Garciaaltares, Young Jin Lee, Pierre Chaurand, X Correig, Pere RafolsAbstract:Mass spectrometry imaging (MSI) has become a mature, widespread analytical technique to perform non-targeted spatial metabolomics. However, the compounds used to promote desorption and ionization of the analyte during acquisition cause spectral interferences in the low mass range that hinder Downstream Data processing in metabolomics applications. Thus, it is advisable to annotate and remove matrix-related peaks to reduce the number of redundant and non-biologically-relevant variables in the Dataset. We have developed rMSIcleanup, an open-source R package to annotate and remove signals from the matrix, according to the matrix chemical composition and the spatial distribution of its ions. To validate the annotation method, rMSIcleanup was challenged with several images acquired using silver-assisted laser desorption ionization MSI (AgLDI MSI). The algorithm was able to correctly classify m/z signals related to silver clusters. Visual exploration of the Data using Principal Component Analysis (PCA) demonstrated that annotation and removal of matrix-related signals improved spectral Data post-processing. The results highlight the need for including matrix-related peak annotation tools such as rMSIcleanup in MSI workflows.
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rmsicleanup an open source tool for matrix related peak annotation in mass spectrometry imaging and its application to silver assisted laser desorption ionization
bioRxiv, 2019Co-Authors: Gerard Baquer, Lluc Semente, Maria Garciaaltares, Young Jin Lee, Pierre Chaurand, X Correig, Pere RafolsAbstract:Abstract Mass spectrometry imaging (MSI) has become a mature, widespread analytical technique to perform non-targeted spatial metabolomics. However, the compounds used to promote desorption and ionization of the analyte during acquisition cause spectral interferences in the low mass range that hinder Downstream Data processing in metabolomics applications. Thus, it is advisable to annotate and remove matrix-related peaks to reduce the number of redundant and non-biologically-relevant variables in the Dataset. We have developed rMSIcleanup, an open-source R package to annotate and remove matrix-related signals based on its chemical formula and the spatial distribution of its ions. To validate the annotation method, rMSIcleanup was challenged with several images acquired using silver-assisted laser desorption ionization MSI (AgLDI MSI). The algorithm was able to correctly classify m/z signals related to silver clusters. Visual exploration of the Data using Principal Component Analysis (PCA) demonstrated that annotation and removal of matrix-related signals improved spectral Data post-processing. The results highlight the need for including matrix-related peak annotation tools such as rMSIcleanup in MSI workflows. Resources availability The R package presented in this publication is freely available under the terms of the GNU General Public License v3.0 at https://github.com/gbaquer/rMSIcleanup. The Datasets used in the experiments can be accessed upon request to the corresponding author.
Leonid G. Kazovsky - One of the best experts on this subject based on the ideXlab platform.
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success a next generation hybrid wdm tdm optical access network architecture
Journal of Lightwave Technology, 2004Co-Authors: Futai An, E S Hu, David Gutierrez, K Shrikhande, Leonid G. KazovskyAbstract:In this paper, the authors propose a next-generation hybrid WDM/TDM optical access network architecture called Stanford University aCCESS or SUCCESS. This architecture provides practical migration steps from current-generation time-division multiplexing (TDM)-passive optical network (PONs) to future WDM optical access networks. The architecture is backward compatible for users on existing TDM-PONs, while simultaneously capable of providing upgraded high-bandwidth services to new users on DWDM-PONs through advanced WDM techniques. The SUCCESS architecture is based on a collector ring and several distribution stars connecting the CO and the users. A semipassive configuration of the Remote Nodes (RNs) enables protection and restoration, making the network resilient to power failures. A novel design of the OLT and DWDM-PON ONUs minimizes the system cost considerably: 1) tunable lasers and receivers at the OLT are shared by all ONUs on the network to reduce the transceiver count and 2) the fast tunable lasers not only generate Downstream Data traffic but also provide DWDM-PON ONUs with optical CW bursts for their upstream Data transmission. Results from an experimental system testbed support the feasibility of the proposed SUCCESS architecture. Also, simulation results of the first SUCCESS DWDM-PON MAC protocol verify that it can efficiently provide bidirectional transmission between the OLT and ONUs over multiple wavelengths with a small number of tunable transmitters and receivers.
Liankuan Chen - One of the best experts on this subject based on the ideXlab platform.
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upstream traffic transmitter using injection locked fabry perot laser diode as modulator for wdm access networks
Electronics Letters, 2002Co-Authors: L Y Chan, F Tong, D T K Tong, Chunkit Chan, Liankuan ChenAbstract:An upstream-traffic transmitter based on a Fabry-Perot laser diode (FP-LD) as modulator is proposed and demonstrated for wavelength division multiplexed (WDM) access networks. By injection-locking the FP-LD with the Downstream wavelength at the optical network unit (ONU), the original Downstream Data can be largely suppressed while the upstream Data can be transmitted on the same injection-locked wavelength by simultaneously directly-modulating the FP-LD.
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demonstration of an onu for wdm access network with Downstream bpsk and upstream remodulated ook Data using injection locked fp laser
European Conference on Optical Communication, 2001Co-Authors: S Y Cheung, L Y Chan, Cheongfat Chan, F Tong, D T K Tong, Liankuan ChenAbstract:We propose an ONU for a WDM access network with 2.5 Gb/s passband BPSK Downstream Data and 1.25 Gb/s OOK upstream Data. The Downstream wavelength is reused to injection-lock a Fabry-Perot (FP) laser diode at the ONU to provide remodulation for the upstream Data.
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demonstration of Data remodulation for upstream traffic in wdm access networks using injection locked fp laser as modulator
Optical Fiber Communication Conference, 2001Co-Authors: L Y Chan, Cheongfat Chan, T K Tong, S Y Cheung, F Tong, Liankuan ChenAbstract:We propose and demonstrate an upstream-traffic remodulation scheme based on injection locking of a FP laser diode on the Downstream wavelength. The original 10 Gbit/s Downstream Data are largely suppressed, allowing simultaneous direct modulation of 1-Gb/s upstream Data with improved signal quality.