The Experts below are selected from a list of 258 Experts worldwide ranked by ideXlab platform
Gabi I Kirchner - One of the best experts on this subject based on the ideXlab platform.
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Sirolimus-induced Drug Fever and ciclosporin-induced leukencephalopathia with seizures in one liver transplant recipient.
World journal of gastroenterology, 2007Co-Authors: Doris Schacherer, Martina Zeitoun, Roland Büttner, Cornelia M. Gelbmann, Aiman Obed, Hans-jürgen Schlitt, Jürgen Schölmerich, Gabi I KirchnerAbstract:We describe the first case of sirolimus-induced Drug Fever in a female liver transplant recipient, with a history of hepatitis C-induced end-stage liver cirrhosis in 1999. In 2005, six years after transplantation, she developed calcineurin inhibitor-induced renal function impairment. Immunosuppression was switched from tacrolimus to sirolimus. Two days after the intake of sirolimus, she developed daily Fever spikes, but no infectious focus was found. Antibiotic therapy had no influence on the Fever. After fourteen days, sirolimus was switched back to tacrolimus and the Fever disappeared. In history, the patient developed ciclosporin-induced generalized seizures eleven days after liver transplantation, followed by the development of a motoric speech disorder. Magnetic resonance imaging (MRI) findings were consistent with leucoencephalopathy, therefore immunosuppressive therapy was changed from ciclosporin to tacrolimus and the neurologic symptoms improved significantly. Our case is the first reported case of sirolimus-induced Drug Fever. In addition, the patient showed the rare occurrence of ciclosporin-induced leukencephalopathy with seizures.
Burke A. Cunha - One of the best experts on this subject based on the ideXlab platform.
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Fever of unknown origin (FUO) in a renal transplant recipient due to Drug Fever from sirolimus
Infection, 2016Co-Authors: Sairah Sharif, May W. Kong, James Drakakis, Burke A. CunhaAbstract:Introduction A variety of medications may cause Drug Fever. Drug Fevers may persist for days to weeks until diagnosis is considered. The diagnosis of Drug Fever is confirmed when there is resolution of Fever within 3 days after the medication is discontinued. Only rarely do undiagnosed Drug Fevers persist for over 3 weeks to meet Fever of unknown origin (FUO) criteria. FUOs due to Drug Fever are uncommon, and Drug Fevers due to immunosuppressive Drugs are very rare.
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Clinical approach to Fever in the neurosurgical intensive care unit: Focus on Drug Fever.
Surgical Neurology International, 2013Co-Authors: Burke A. CunhaAbstract:As Fever is one of the cardinal signs of infection, the presence of Fever in a patient in the neurosurgical intensive care unit (NSICU) raises the question of whether it is infectious in etiology. Infectious and noninfectious causes of Fever in the NSICU may be determined based upon assessment of clinical signs and symptoms, the degree of temperature elevation, the relationship of the pulse to the Fever (e.g., an infectious process resulting in hyperpyrexia and bradycardia), and when the Fever occurs (e.g., related to the length of stay in the NSICU). There are many noninfectious disorders which contribute to temperatures >102°F in the NSICU; these include Drug Fevers, deep vein thrombosis, phlebitis/pulmonary embolism, acute myocardial infarction, atelectasis, dehydration, acute gout flare, malignancy, acute pancreatitis, transfusion associated hepatitis, and hemorrhage. Infectious rather than noninfectious disorders, however, are more typically associated with high-grade Fevers (>102°F.) in the NSICU, and nosocomial pneumonia, (synonymous with ventilator-associated pneumonia [VAP]), is the leading culprit, followed by nosocomial infections and Clostridium difficile.
Matthew T. V. Chan - One of the best experts on this subject based on the ideXlab platform.
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Drug Fever induced by piperacillin tazobactam in a scoliosis patient a case report
Medicine, 2015Co-Authors: Jianxiong Shen, Matthew T. V. ChanAbstract:Drug Fever is frequently underrecognized by clinicians despite its common occurrence. Fever induced by piperacillin/tazobactam has not been reported in scoliosis correction surgery.Drug Fever caused by piperacillin/tazobactam in a scoliosis patient was described.A 36-year-old woman with adult scoliosis undergoing correction surgery was reported. She developed a Fever after an intake of piperacillin/tazobactam for 3 days. Eosinophil count, erythrocyte sedimentation rate, and C-reactive proteins were increased in her blood examination. Thorough history, chest radiography, blood cultures, physical examination, and urinalysis revealed no evidences of Fever. A Drug Fever is therefore considered. The Fever lasted for 2 weeks and her body temperature come back to normal 4 days after piperacillin/tazobactam cessation.Fever could be caused by piperacillin/tazobactam. The Drug Fever's diagnosis is easily confounded by a co-occurring infection. Therefore, it is crucial for clinicians to doubt Drugs as a reason when no other origin of Fever could be identified in a patient.
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Drug Fever Induced by Piperacillin/Tazobactam in a Scoliosis Patient: A Case Report.
Medicine, 2015Co-Authors: Jianxiong Shen, Matthew T. V. ChanAbstract:Drug Fever is frequently underrecognized by clinicians despite its common occurrence. Fever induced by piperacillin/tazobactam has not been reported in scoliosis correction surgery.Drug Fever caused by piperacillin/tazobactam in a scoliosis patient was described.A 36-year-old woman with adult scoliosis undergoing correction surgery was reported. She developed a Fever after an intake of piperacillin/tazobactam for 3 days. Eosinophil count, erythrocyte sedimentation rate, and C-reactive proteins were increased in her blood examination. Thorough history, chest radiography, blood cultures, physical examination, and urinalysis revealed no evidences of Fever. A Drug Fever is therefore considered. The Fever lasted for 2 weeks and her body temperature come back to normal 4 days after piperacillin/tazobactam cessation.Fever could be caused by piperacillin/tazobactam. The Drug Fever's diagnosis is easily confounded by a co-occurring infection. Therefore, it is crucial for clinicians to doubt Drugs as a reason when no other origin of Fever could be identified in a patient.
Doris Schacherer - One of the best experts on this subject based on the ideXlab platform.
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Sirolimus-induced Drug Fever and ciclosporin-induced leukencephalopathia with seizures in one liver transplant recipient.
World journal of gastroenterology, 2007Co-Authors: Doris Schacherer, Martina Zeitoun, Roland Büttner, Cornelia M. Gelbmann, Aiman Obed, Hans-jürgen Schlitt, Jürgen Schölmerich, Gabi I KirchnerAbstract:We describe the first case of sirolimus-induced Drug Fever in a female liver transplant recipient, with a history of hepatitis C-induced end-stage liver cirrhosis in 1999. In 2005, six years after transplantation, she developed calcineurin inhibitor-induced renal function impairment. Immunosuppression was switched from tacrolimus to sirolimus. Two days after the intake of sirolimus, she developed daily Fever spikes, but no infectious focus was found. Antibiotic therapy had no influence on the Fever. After fourteen days, sirolimus was switched back to tacrolimus and the Fever disappeared. In history, the patient developed ciclosporin-induced generalized seizures eleven days after liver transplantation, followed by the development of a motoric speech disorder. Magnetic resonance imaging (MRI) findings were consistent with leucoencephalopathy, therefore immunosuppressive therapy was changed from ciclosporin to tacrolimus and the neurologic symptoms improved significantly. Our case is the first reported case of sirolimus-induced Drug Fever. In addition, the patient showed the rare occurrence of ciclosporin-induced leukencephalopathy with seizures.
Jianxiong Shen - One of the best experts on this subject based on the ideXlab platform.
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Drug Fever induced by piperacillin tazobactam in a scoliosis patient a case report
Medicine, 2015Co-Authors: Jianxiong Shen, Matthew T. V. ChanAbstract:Drug Fever is frequently underrecognized by clinicians despite its common occurrence. Fever induced by piperacillin/tazobactam has not been reported in scoliosis correction surgery.Drug Fever caused by piperacillin/tazobactam in a scoliosis patient was described.A 36-year-old woman with adult scoliosis undergoing correction surgery was reported. She developed a Fever after an intake of piperacillin/tazobactam for 3 days. Eosinophil count, erythrocyte sedimentation rate, and C-reactive proteins were increased in her blood examination. Thorough history, chest radiography, blood cultures, physical examination, and urinalysis revealed no evidences of Fever. A Drug Fever is therefore considered. The Fever lasted for 2 weeks and her body temperature come back to normal 4 days after piperacillin/tazobactam cessation.Fever could be caused by piperacillin/tazobactam. The Drug Fever's diagnosis is easily confounded by a co-occurring infection. Therefore, it is crucial for clinicians to doubt Drugs as a reason when no other origin of Fever could be identified in a patient.
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Drug Fever Induced by Piperacillin/Tazobactam in a Scoliosis Patient: A Case Report.
Medicine, 2015Co-Authors: Jianxiong Shen, Matthew T. V. ChanAbstract:Drug Fever is frequently underrecognized by clinicians despite its common occurrence. Fever induced by piperacillin/tazobactam has not been reported in scoliosis correction surgery.Drug Fever caused by piperacillin/tazobactam in a scoliosis patient was described.A 36-year-old woman with adult scoliosis undergoing correction surgery was reported. She developed a Fever after an intake of piperacillin/tazobactam for 3 days. Eosinophil count, erythrocyte sedimentation rate, and C-reactive proteins were increased in her blood examination. Thorough history, chest radiography, blood cultures, physical examination, and urinalysis revealed no evidences of Fever. A Drug Fever is therefore considered. The Fever lasted for 2 weeks and her body temperature come back to normal 4 days after piperacillin/tazobactam cessation.Fever could be caused by piperacillin/tazobactam. The Drug Fever's diagnosis is easily confounded by a co-occurring infection. Therefore, it is crucial for clinicians to doubt Drugs as a reason when no other origin of Fever could be identified in a patient.
