The Experts below are selected from a list of 2556 Experts worldwide ranked by ideXlab platform
Daw Pierce - One of the best experts on this subject based on the ideXlab platform.
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effect of heated humidification on compliance and quality of life in patients with sleep apnea using nasal continuous positive airway pressure
Chest, 2005Co-Authors: Jeffery M Mado, Matthew Krauza, Adna Pervez, Daw PierceAbstract:Study objective To determine whether the addition of heated humidification at treatment initiation with nasal continuous positive airway pressure (CPAP) would lead to better CPAP compliance and improve quality of life and subjective sleepiness in patients with sleep apnea. Design Randomized controlled trial. Setting An academic sleep center located at a Veterans Affairs hospital. Patients Ninety-eight patients with obstructive sleep apnea who had not received nasal CPAP previously. Measurements and results Patients received heated humidification at CPAP initiation in the treatment group. In the control group, patients could receive heated humidification only if they had upper airway symptoms that could not be treated successfully with simpler measures. Patients were followed up at 1 month, 3 months, and 12 months. Outcome measures were compliance with nasal CPAP (mean hours per night at effective pressure), quality of life as measured by the Calgary sleep apnea quality of life index, subjective sleepiness measured with the Epworth sleepiness scale, and CPAP side effects. There was no difference in CPAP compliance between groups. Quality of life and subjective sleepiness improved in both groups with nasal CPAP therapy, but there was no difference in the extent of improvement between groups. The overall CPAP side effect score was similar in both groups, but individual symptoms of Dry Nose and Dry mouth and throat were significantly lower in the heated humidification group. Conclusions The addition of heated humidification when nasal CPAP was instituted did not lead to better compliance, greater improvement in sleepiness, or improved quality of life, but was associated with fewer symptoms attributable to the upper airway.
Gle N Richards - One of the best experts on this subject based on the ideXlab platform.
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effects of humidification on nasal symptoms and compliance in sleep apnea patients using continuous positive airway pressure
Chest, 1999Co-Authors: Clifford A Massie, Kathlee Peralez, Gle N RichardsAbstract:Study objectives To evaluate the effects of humidification on nasal symptoms and compliance in sleep apnea patients using continuous positive airway pressure (CPAP). Design A randomized, crossover design was employed. Setting The study was conducted at two suburban community-based hospital sleep laboratories. Patients Data were collected on 38 obstructive sleep apnea patients (mean age, 44.1 years) in whom CPAP was a novel treatment. Interventions The interventions were heated humidity, cold passover humidity, and a washout period without humidity. Measurements and results Patients were titrated with heated humidity or cold passover humidity in the laboratory and subsequently initiated on humidity. Objective compliance, self-report of factors affecting CPAP use, satisfaction with CPAP, feeling upon awakening, and daytime sleepiness were assessed at the completion of each 3-week treatment period and a 2-week washout period. Outcome measures were assessed with one-way analysis of variance followed by Scheffe post hoc comparisons. Significant main effects were observed for compliance (F 2,37 = 5.2; p = 0.008), satisfaction with CPAP (F 2,37 = 4.5; p = 0.01), and feeling refreshed on awakening (F 2,37 = 4.4; p = 0.02). A significant decrease in daytime sleepiness was observed between baseline and each of the conditions (F 3,37 = 55.5; p 0.56). CPAP use with heated humidity (5.52 ± 2.1 h/night) was greater than CPAP use without humidity (4.93 ± 2.2 h/night; p = 0.008). Compliance differences were not observed between CPAP use with cold passover humidity and CPAP use without humidity. Patients were more satisfied with CPAP when it was used with heated or cold passover humidity (p ≤ 0.05). However, only heated humidity resulted in feeling more refreshed on awakening (p 2,37 = 2.5; p = 0.09). Specific side effects such as Dry mouth or throat and Dry Nose were reported less frequently when CPAP was used with heated humidity compared to CPAP use without humidity (p Conclusions Compliance with CPAP is enhanced when heated humidification is employed. This is likely due to a reduction in side effects associated with upper airway symptoms and a more refreshed feeling upon awakening. Compliance gains may be realized sooner if patients are started with heated humidity at CPAP initiation.
Jeffery M Mado - One of the best experts on this subject based on the ideXlab platform.
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effect of heated humidification on compliance and quality of life in patients with sleep apnea using nasal continuous positive airway pressure
Chest, 2005Co-Authors: Jeffery M Mado, Matthew Krauza, Adna Pervez, Daw PierceAbstract:Study objective To determine whether the addition of heated humidification at treatment initiation with nasal continuous positive airway pressure (CPAP) would lead to better CPAP compliance and improve quality of life and subjective sleepiness in patients with sleep apnea. Design Randomized controlled trial. Setting An academic sleep center located at a Veterans Affairs hospital. Patients Ninety-eight patients with obstructive sleep apnea who had not received nasal CPAP previously. Measurements and results Patients received heated humidification at CPAP initiation in the treatment group. In the control group, patients could receive heated humidification only if they had upper airway symptoms that could not be treated successfully with simpler measures. Patients were followed up at 1 month, 3 months, and 12 months. Outcome measures were compliance with nasal CPAP (mean hours per night at effective pressure), quality of life as measured by the Calgary sleep apnea quality of life index, subjective sleepiness measured with the Epworth sleepiness scale, and CPAP side effects. There was no difference in CPAP compliance between groups. Quality of life and subjective sleepiness improved in both groups with nasal CPAP therapy, but there was no difference in the extent of improvement between groups. The overall CPAP side effect score was similar in both groups, but individual symptoms of Dry Nose and Dry mouth and throat were significantly lower in the heated humidification group. Conclusions The addition of heated humidification when nasal CPAP was instituted did not lead to better compliance, greater improvement in sleepiness, or improved quality of life, but was associated with fewer symptoms attributable to the upper airway.
Patrick Levy - One of the best experts on this subject based on the ideXlab platform.
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side effects of nasal continuous positive airway pressure in sleep apnea syndrome study of 193 patients in two french sleep centers
Chest, 1995Co-Authors: Jeanlouis Pepin, P Leger, Dan Veale, Bruno Langevin, Dominique Robert, Patrick LevyAbstract:Nasal continuous positive airway pressure (N-CPAP) is now the treatment of choice for patients with sleep apnea syndrome (SAS). Side effects and adverse reactions have been described with this device. We have therefore systematically studied side effects of N-CPAP in 193 patients recruited consecutively from two French sleep centers (Lyon and Grenoble). Patients were followed up with repeated polysomnography, clinical assessment, and a formal questionnaire about subjective benefits and side effects of treatment. The patients (mean age, 59 +/- 12 years) were obese (body mass index, 32 +/- 7 kg/m2) and had been using N-CPAP for 19 +/- 17 months for moderate to severe SAS (respiratory disturbance index [RDI] = 53 +/- 25/h). The clinical presentation was the same in the two sleep centers. Fifty percent of the patients complained of at least one side effect due to the nasal mask (allergy to the face, air leaks, abrasions of the ridge of the Nose). Using individually molded masks, the patients exhibited fewer abrasions of the bridge of the Nose (p < 0.01) and had red eyes every morning in only 9% of cases vs 24% for the patients using industrial silicone nasal masks (p < 0.025). Patients with silicone nasal masks also had more allergic reaction to the face (13% vs 5%), but this difference did not reach significance. Dry Nose or mouth in the morning affected 65% of the patients. Sneezing and nasal drip were present in more than 35% of the subjects and nasal congestion in 25%. When the patients were separated in two groups, whether or not using a humidifier, no difference was found for any of the side effects described. The clinical presentation as to the clinical benefits obtained from N-CPAP were different when comparing mild vs moderate-to-severe SAS. However, no differences were shown in the two subgroups regarding the side effects due to the nasal mask. The discomfort of the N-CPAP apparatus in terms of noise was described more frequently in the subgroup with mild SAS. We did not observe any correlation between the side effects and the level of pressure used during N-CPAP. The rate of compliance remains high with a daily use of 6.5 +/- 3 h, with 88% of the patients using their device every night. This could be explained by the clinical benefit obtained: only 1% of the patients had no subjective benefit induced by their therapy.(ABSTRACT TRUNCATED AT 400 WORDS)
Clifford A Massie - One of the best experts on this subject based on the ideXlab platform.
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effects of humidification on nasal symptoms and compliance in sleep apnea patients using continuous positive airway pressure
Chest, 1999Co-Authors: Clifford A Massie, Kathlee Peralez, Gle N RichardsAbstract:Study objectives To evaluate the effects of humidification on nasal symptoms and compliance in sleep apnea patients using continuous positive airway pressure (CPAP). Design A randomized, crossover design was employed. Setting The study was conducted at two suburban community-based hospital sleep laboratories. Patients Data were collected on 38 obstructive sleep apnea patients (mean age, 44.1 years) in whom CPAP was a novel treatment. Interventions The interventions were heated humidity, cold passover humidity, and a washout period without humidity. Measurements and results Patients were titrated with heated humidity or cold passover humidity in the laboratory and subsequently initiated on humidity. Objective compliance, self-report of factors affecting CPAP use, satisfaction with CPAP, feeling upon awakening, and daytime sleepiness were assessed at the completion of each 3-week treatment period and a 2-week washout period. Outcome measures were assessed with one-way analysis of variance followed by Scheffe post hoc comparisons. Significant main effects were observed for compliance (F 2,37 = 5.2; p = 0.008), satisfaction with CPAP (F 2,37 = 4.5; p = 0.01), and feeling refreshed on awakening (F 2,37 = 4.4; p = 0.02). A significant decrease in daytime sleepiness was observed between baseline and each of the conditions (F 3,37 = 55.5; p 0.56). CPAP use with heated humidity (5.52 ± 2.1 h/night) was greater than CPAP use without humidity (4.93 ± 2.2 h/night; p = 0.008). Compliance differences were not observed between CPAP use with cold passover humidity and CPAP use without humidity. Patients were more satisfied with CPAP when it was used with heated or cold passover humidity (p ≤ 0.05). However, only heated humidity resulted in feeling more refreshed on awakening (p 2,37 = 2.5; p = 0.09). Specific side effects such as Dry mouth or throat and Dry Nose were reported less frequently when CPAP was used with heated humidity compared to CPAP use without humidity (p Conclusions Compliance with CPAP is enhanced when heated humidification is employed. This is likely due to a reduction in side effects associated with upper airway symptoms and a more refreshed feeling upon awakening. Compliance gains may be realized sooner if patients are started with heated humidity at CPAP initiation.
