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M Brennenstuhl - One of the best experts on this subject based on the ideXlab platform.
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omeprazole amoxycillin therapy for eradication of helicobacter pylori in Duodenal Ulcer Bleeding preliminary results of a pilot study
Journal of Gastroenterology, 1995Co-Authors: D Jaspersen, T Korner, W Schorr, M BrennenstuhlAbstract:Thirty-five patients with Duodenal Ulcer Bleeding andHelicobacter pylori-colonization were assigned to receive 2×20 mg omeprazole and 3×750 mg amoxycillin daily for 2 weeks. Eradication was defined as no evidence ofH. pylori infection by urease test and by histology 4 weeks after completion of therapy. Two patients were lost to follow up. All Ulcers healed completely (100% Ulcer healing rate). Twenty-nine out of the 33 patients wereH. pylori-negative (87.9% eradication rate). Three patients complained of typical side effects of amoxycillin (9.1% side effect rate). The patients were prospectively followed for 12 months. After Ulcer healing, no maintenance therapy was given. One of the 29 patients in whomH. pylori eradication had been successful suffered a second Ulcer hemorrhage withH. pylori re-infection (3.4% relapse rate of Ulcer Bleeding), and this was managed endoscopically. Recurrent Ulcer hemorrhage occurred in 2 out of 4H. pylori-resistant patients. At the end of the follow-up period, of the patients in whomH. pylori eradication had been initially successful, only the patient with re-Bleeding remained re-infected. The 4H. pylori-resistant patients showed persistentH. pylori colonization. In conclusion, omeprazole plus amoxycillin is a safe and effective treatment for eradicatingH. pylori; this treatment reduces the relapse rate of Duodenal Ulcer Bleeding.
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Omeprazole-amoxycillin therapy for eradication ofHelicobacter pylori in Duodenal Ulcer Bleeding: Preliminary results of a pilot study
Journal of Gastroenterology, 1995Co-Authors: D Jaspersen, T Korner, W Schorr, M BrennenstuhlAbstract:Thirty-five patients with Duodenal Ulcer Bleeding and Helicobacter pylori -colonization were assigned to receive 2×20 mg omeprazole and 3×750 mg amoxycillin daily for 2 weeks. Eradication was defined as no evidence of H. pylori infection by urease test and by histology 4 weeks after completion of therapy. Two patients were lost to follow up. All Ulcers healed completely (100% Ulcer healing rate). Twenty-nine out of the 33 patients were H. pylori -negative (87.9% eradication rate). Three patients complained of typical side effects of amoxycillin (9.1% side effect rate). The patients were prospectively followed for 12 months. After Ulcer healing, no maintenance therapy was given. One of the 29 patients in whom H. pylori eradication had been successful suffered a second Ulcer hemorrhage with H. pylori re-infection (3.4% relapse rate of Ulcer Bleeding), and this was managed endoscopically. Recurrent Ulcer hemorrhage occurred in 2 out of 4 H. pylori -resistant patients. At the end of the follow-up period, of the patients in whom H. pylori eradication had been initially successful, only the patient with re-Bleeding remained re-infected. The 4 H. pylori -resistant patients showed persistent H. pylori colonization. In conclusion, omeprazole plus amoxycillin is a safe and effective treatment for eradicating H. pylori ; this treatment reduces the relapse rate of Duodenal Ulcer Bleeding.
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Helicobacter pylori eradication reduces the rate of reBleeding in Ulcer hemorrhage
Gastrointestinal Endoscopy, 1995Co-Authors: D Jaspersen, M Brennenstuhl, Th. Koerner, Schorr W, C. Raschka, C.-h. HammarAbstract:Abstract To evaluate whether eradication with omeprazole and amoxicillin results in a reduction of Ulcer recurrence and reBleeding in patients with Helicobacter pylori -associated Duodenal Ulcer hemorrhage, patients with upper gastrointestinal hemorrhage from Duodenal Ulcers with stigmata of recent hemorrhage, a drop in hemoglobin level of more than 2 g/dL, and documented H. pylori infection (by rapid urease test and histologic findings) were randomly assigned to receive omeprazole, 40 mg every day, and amoxicillin, 1 g twice a day, (Group A) or omeprazole alone, 40 mg every day, (Group B) for 2 weeks. No maintenance antiUlcer therapy was given. Patients underwent a second endoscopy 4 weeks after completion of therapy and were followed for 1 year. Endoscopy was performed again at the end of 1 year. All patients showed Ulcer healing 4 weeks after completion of therapy. H. pylori eradication rates were 83% (Group A) and 5% (Group B) ( p p p p H. pylori significantly reduces the rates of Ulcer recurrence and reBleeding in patients with Duodenal Ulcer Bleeding. Dual therapy with omeprazole and amoxicillin should be considered in all H. pylori -positive patients with hemorrhage from Duodenal Ulcers. (Gastrointest Endosc 1995;41:5-7.)
D Jaspersen - One of the best experts on this subject based on the ideXlab platform.
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omeprazole amoxycillin therapy for eradication of helicobacter pylori in Duodenal Ulcer Bleeding preliminary results of a pilot study
Journal of Gastroenterology, 1995Co-Authors: D Jaspersen, T Korner, W Schorr, M BrennenstuhlAbstract:Thirty-five patients with Duodenal Ulcer Bleeding andHelicobacter pylori-colonization were assigned to receive 2×20 mg omeprazole and 3×750 mg amoxycillin daily for 2 weeks. Eradication was defined as no evidence ofH. pylori infection by urease test and by histology 4 weeks after completion of therapy. Two patients were lost to follow up. All Ulcers healed completely (100% Ulcer healing rate). Twenty-nine out of the 33 patients wereH. pylori-negative (87.9% eradication rate). Three patients complained of typical side effects of amoxycillin (9.1% side effect rate). The patients were prospectively followed for 12 months. After Ulcer healing, no maintenance therapy was given. One of the 29 patients in whomH. pylori eradication had been successful suffered a second Ulcer hemorrhage withH. pylori re-infection (3.4% relapse rate of Ulcer Bleeding), and this was managed endoscopically. Recurrent Ulcer hemorrhage occurred in 2 out of 4H. pylori-resistant patients. At the end of the follow-up period, of the patients in whomH. pylori eradication had been initially successful, only the patient with re-Bleeding remained re-infected. The 4H. pylori-resistant patients showed persistentH. pylori colonization. In conclusion, omeprazole plus amoxycillin is a safe and effective treatment for eradicatingH. pylori; this treatment reduces the relapse rate of Duodenal Ulcer Bleeding.
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Omeprazole-amoxycillin therapy for eradication ofHelicobacter pylori in Duodenal Ulcer Bleeding: Preliminary results of a pilot study
Journal of Gastroenterology, 1995Co-Authors: D Jaspersen, T Korner, W Schorr, M BrennenstuhlAbstract:Thirty-five patients with Duodenal Ulcer Bleeding and Helicobacter pylori -colonization were assigned to receive 2×20 mg omeprazole and 3×750 mg amoxycillin daily for 2 weeks. Eradication was defined as no evidence of H. pylori infection by urease test and by histology 4 weeks after completion of therapy. Two patients were lost to follow up. All Ulcers healed completely (100% Ulcer healing rate). Twenty-nine out of the 33 patients were H. pylori -negative (87.9% eradication rate). Three patients complained of typical side effects of amoxycillin (9.1% side effect rate). The patients were prospectively followed for 12 months. After Ulcer healing, no maintenance therapy was given. One of the 29 patients in whom H. pylori eradication had been successful suffered a second Ulcer hemorrhage with H. pylori re-infection (3.4% relapse rate of Ulcer Bleeding), and this was managed endoscopically. Recurrent Ulcer hemorrhage occurred in 2 out of 4 H. pylori -resistant patients. At the end of the follow-up period, of the patients in whom H. pylori eradication had been initially successful, only the patient with re-Bleeding remained re-infected. The 4 H. pylori -resistant patients showed persistent H. pylori colonization. In conclusion, omeprazole plus amoxycillin is a safe and effective treatment for eradicating H. pylori ; this treatment reduces the relapse rate of Duodenal Ulcer Bleeding.
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Helicobacter pylori eradication reduces the rate of reBleeding in Ulcer hemorrhage
Gastrointestinal Endoscopy, 1995Co-Authors: D Jaspersen, M Brennenstuhl, Th. Koerner, Schorr W, C. Raschka, C.-h. HammarAbstract:Abstract To evaluate whether eradication with omeprazole and amoxicillin results in a reduction of Ulcer recurrence and reBleeding in patients with Helicobacter pylori -associated Duodenal Ulcer hemorrhage, patients with upper gastrointestinal hemorrhage from Duodenal Ulcers with stigmata of recent hemorrhage, a drop in hemoglobin level of more than 2 g/dL, and documented H. pylori infection (by rapid urease test and histologic findings) were randomly assigned to receive omeprazole, 40 mg every day, and amoxicillin, 1 g twice a day, (Group A) or omeprazole alone, 40 mg every day, (Group B) for 2 weeks. No maintenance antiUlcer therapy was given. Patients underwent a second endoscopy 4 weeks after completion of therapy and were followed for 1 year. Endoscopy was performed again at the end of 1 year. All patients showed Ulcer healing 4 weeks after completion of therapy. H. pylori eradication rates were 83% (Group A) and 5% (Group B) ( p p p p H. pylori significantly reduces the rates of Ulcer recurrence and reBleeding in patients with Duodenal Ulcer Bleeding. Dual therapy with omeprazole and amoxicillin should be considered in all H. pylori -positive patients with hemorrhage from Duodenal Ulcers. (Gastrointest Endosc 1995;41:5-7.)
Jae Bock Chung - One of the best experts on this subject based on the ideXlab platform.
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a case of intramural Duodenal hematoma accompanied by acute pancreatitis following endoscopic hemostasis for Duodenal Ulcer Bleeding
The Korean Journal of Gastroenterology, 2009Co-Authors: Min Keun Song, Joon Beom Shin, Ha Na Park, Ki Cheun Jeong, Jae Bock ChungAbstract:Intramural Duodenal hematoma is an uncommon condition, which usually develops after blunt abdominal trauma. It is also reported as a complication of anticoagulant therapy, blood dyscrasia, pancreatic disease, and diagnostic and therapeutic endoscopy. The typical clinical pictures of intramural Duodenal hematoma consist of upper abdominal pain, vomiting, fever, and hematochezia, and it is rarely accompanied by intestinal obstruction, peritonitis, and pancreatitis as its complication. We report a case of intramural Duodenal hematoma extended to peritoneal cavity, and accompanied by acute pancreatitis following therapeutic endoscopy for Duodenal Ulcer Bleeding in a 32-year-old man who was on maintenance of anti-coagulation therapy after valvular heart surgery.
Young Jun Choi - One of the best experts on this subject based on the ideXlab platform.
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a case of Duodenal Ulcer Bleeding caused by pancreatic arteriovenous malformation
Clinical Endoscopy, 2005Co-Authors: Seil Oh, Ilno Do, Young Jun ChoiAbstract:Arteriovenous malformation (AVM) of the pancreas is an extremely rare disease. It may be asymptomatic, but more than half of the patients present with gastrointestinal Bleeding. The most common cause of the gastrointestinal Bleeding is variceal Bleeding due to the portal hypertension resulting from AVM. Bleeding from a Duodenal Ulcer and AVM to the pancreatic duct are rare findings. Surgical excision is the treatment of choice, but when portal hypertension has developed, this cannot be corrected even after surgical resection. We experienced a case of recurrent Duodenal Ulcer Bleeding that was due to arteriovenous malformation in the head of the pancreas in a 45 year old man. He was successfully treated with pylorus preserving pancreaticoduodenectomy.
W Schorr - One of the best experts on this subject based on the ideXlab platform.
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omeprazole amoxycillin therapy for eradication of helicobacter pylori in Duodenal Ulcer Bleeding preliminary results of a pilot study
Journal of Gastroenterology, 1995Co-Authors: D Jaspersen, T Korner, W Schorr, M BrennenstuhlAbstract:Thirty-five patients with Duodenal Ulcer Bleeding andHelicobacter pylori-colonization were assigned to receive 2×20 mg omeprazole and 3×750 mg amoxycillin daily for 2 weeks. Eradication was defined as no evidence ofH. pylori infection by urease test and by histology 4 weeks after completion of therapy. Two patients were lost to follow up. All Ulcers healed completely (100% Ulcer healing rate). Twenty-nine out of the 33 patients wereH. pylori-negative (87.9% eradication rate). Three patients complained of typical side effects of amoxycillin (9.1% side effect rate). The patients were prospectively followed for 12 months. After Ulcer healing, no maintenance therapy was given. One of the 29 patients in whomH. pylori eradication had been successful suffered a second Ulcer hemorrhage withH. pylori re-infection (3.4% relapse rate of Ulcer Bleeding), and this was managed endoscopically. Recurrent Ulcer hemorrhage occurred in 2 out of 4H. pylori-resistant patients. At the end of the follow-up period, of the patients in whomH. pylori eradication had been initially successful, only the patient with re-Bleeding remained re-infected. The 4H. pylori-resistant patients showed persistentH. pylori colonization. In conclusion, omeprazole plus amoxycillin is a safe and effective treatment for eradicatingH. pylori; this treatment reduces the relapse rate of Duodenal Ulcer Bleeding.
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Omeprazole-amoxycillin therapy for eradication ofHelicobacter pylori in Duodenal Ulcer Bleeding: Preliminary results of a pilot study
Journal of Gastroenterology, 1995Co-Authors: D Jaspersen, T Korner, W Schorr, M BrennenstuhlAbstract:Thirty-five patients with Duodenal Ulcer Bleeding and Helicobacter pylori -colonization were assigned to receive 2×20 mg omeprazole and 3×750 mg amoxycillin daily for 2 weeks. Eradication was defined as no evidence of H. pylori infection by urease test and by histology 4 weeks after completion of therapy. Two patients were lost to follow up. All Ulcers healed completely (100% Ulcer healing rate). Twenty-nine out of the 33 patients were H. pylori -negative (87.9% eradication rate). Three patients complained of typical side effects of amoxycillin (9.1% side effect rate). The patients were prospectively followed for 12 months. After Ulcer healing, no maintenance therapy was given. One of the 29 patients in whom H. pylori eradication had been successful suffered a second Ulcer hemorrhage with H. pylori re-infection (3.4% relapse rate of Ulcer Bleeding), and this was managed endoscopically. Recurrent Ulcer hemorrhage occurred in 2 out of 4 H. pylori -resistant patients. At the end of the follow-up period, of the patients in whom H. pylori eradication had been initially successful, only the patient with re-Bleeding remained re-infected. The 4 H. pylori -resistant patients showed persistent H. pylori colonization. In conclusion, omeprazole plus amoxycillin is a safe and effective treatment for eradicating H. pylori ; this treatment reduces the relapse rate of Duodenal Ulcer Bleeding.
