The Experts below are selected from a list of 6642 Experts worldwide ranked by ideXlab platform
Hidenori Oguchi - One of the best experts on this subject based on the ideXlab platform.
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Incidence of posterior reversible encephalopathy syndrome in eclamptic and patients with preEclampsia with neurologic symptoms
American journal of obstetrics and gynecology, 2016Co-Authors: Michinori Mayama, Kaname Uno, Sho Tano, Masato Yoshihara, Mayu Ukai, Yasuyuki Kishigami, Yasuhiro Ito, Hidenori OguchiAbstract:Background Posterior reversible encephalopathy syndrome is observed frequently in patients with Eclampsia; however, it has also been reported in some patients with preEclampsia. Objectives The aim of this study was to determine the incidence of posterior reversible encephalopathy syndrome in patients with preEclampsia and Eclampsia and to assess whether these 2 patient groups share similar pathophysiologic backgrounds by comparing clinical and radiologic characteristics. Study Design This was a retrospective cohort study of 4849 pregnant patients. A total of 49 patients with Eclampsia and preEclampsia and with neurologic symptoms underwent magnetic resonance imaging and magnetic resonance angiography; 10 patients were excluded from further analysis because of a history of epilepsy or dissociative disorder. The age, parity, blood pressure, and routine laboratory data at the onset of symptoms were also recorded. Results Among 39 patients with neurologic symptoms, 12 of 13 patients with Eclampsia (92.3%) and 5 of 26 patients with preEclampsia (19.2%) experienced the development of posterior reversible encephalopathy syndrome. Whereas age and blood pressure at onset were not significantly different between patients with and without encephalopathy, hematocrit, serum creatinine, aspartate transaminase, alanine transaminase, and lactate dehydrogenase values were significantly higher in patients with posterior reversible encephalopathy syndrome than in those without magnetic resonance imaging abnormalities. In contrast, patients with Eclampsia with posterior reversible encephalopathy syndrome did not show any significant differences in clinical and laboratory data compared with patients with preEclampsia with posterior reversible encephalopathy syndrome. In addition to the parietooccipital regions, atypical regions (such as the frontal and temporal lobes), and basal ganglia were also involved in patients with Eclampsia and patients with preEclampsia with posterior reversible encephalopathy syndrome. Finally, intraparenchymal hemorrhage was detected in 1 patient with Eclampsia, and subarachnoid hemorrhage was observed in 1 patient with preEclampsia. Conclusions Although the incidence of posterior reversible encephalopathy syndrome was high in patients with Eclampsia, nearly 20% of the patients with preEclampsia with neurologic symptoms also experienced posterior reversible encephalopathy syndrome. The similarities in clinical and radiologic findings of posterior reversible encephalopathy syndrome between the 2 groups support the hypothesis that these 2 patient groups have a shared pathophysiologic background. Thus, magnetic resonance imaging studies should be considered for patients with the recent onset of neurologic symptoms, regardless of the development of Eclampsia.
Aruna Jain - One of the best experts on this subject based on the ideXlab platform.
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Atypical presentation of posterior reversible encephalopathy syndrome: Two cases
Journal of anaesthesiology clinical pharmacology, 2018Co-Authors: Nishant Kumar, Ranju Singh, Neha Sharma, Aruna JainAbstract:Posterior reversible encephalopathy syndrome (PRES) is a clinico-neuroradiological entity, first described in 1996. It is commonly associated with systemic hypertension, intake of immunosuppressant drugs, sepsis and Eclampsia and preEclampsia. Headache, alteration in consciousness, visual disturbances and seizures are common manifestations of PRES. Signs of pyramidal tract involvement and motor dysfunction are uncommon clinical findings. However, clinical presentation is not diagnostic. On neuroimaging, lesions are characteristically found in parieto occipital region of the brain due to vasogenic edema. We report two cases of PRES with atypical clinical presentation-one which was suggestive of neurocysticercosis and the other in which agitation and opisthotonic posture were predominant features.
Michinori Mayama - One of the best experts on this subject based on the ideXlab platform.
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Incidence of posterior reversible encephalopathy syndrome in eclamptic and patients with preEclampsia with neurologic symptoms
American journal of obstetrics and gynecology, 2016Co-Authors: Michinori Mayama, Kaname Uno, Sho Tano, Masato Yoshihara, Mayu Ukai, Yasuyuki Kishigami, Yasuhiro Ito, Hidenori OguchiAbstract:Background Posterior reversible encephalopathy syndrome is observed frequently in patients with Eclampsia; however, it has also been reported in some patients with preEclampsia. Objectives The aim of this study was to determine the incidence of posterior reversible encephalopathy syndrome in patients with preEclampsia and Eclampsia and to assess whether these 2 patient groups share similar pathophysiologic backgrounds by comparing clinical and radiologic characteristics. Study Design This was a retrospective cohort study of 4849 pregnant patients. A total of 49 patients with Eclampsia and preEclampsia and with neurologic symptoms underwent magnetic resonance imaging and magnetic resonance angiography; 10 patients were excluded from further analysis because of a history of epilepsy or dissociative disorder. The age, parity, blood pressure, and routine laboratory data at the onset of symptoms were also recorded. Results Among 39 patients with neurologic symptoms, 12 of 13 patients with Eclampsia (92.3%) and 5 of 26 patients with preEclampsia (19.2%) experienced the development of posterior reversible encephalopathy syndrome. Whereas age and blood pressure at onset were not significantly different between patients with and without encephalopathy, hematocrit, serum creatinine, aspartate transaminase, alanine transaminase, and lactate dehydrogenase values were significantly higher in patients with posterior reversible encephalopathy syndrome than in those without magnetic resonance imaging abnormalities. In contrast, patients with Eclampsia with posterior reversible encephalopathy syndrome did not show any significant differences in clinical and laboratory data compared with patients with preEclampsia with posterior reversible encephalopathy syndrome. In addition to the parietooccipital regions, atypical regions (such as the frontal and temporal lobes), and basal ganglia were also involved in patients with Eclampsia and patients with preEclampsia with posterior reversible encephalopathy syndrome. Finally, intraparenchymal hemorrhage was detected in 1 patient with Eclampsia, and subarachnoid hemorrhage was observed in 1 patient with preEclampsia. Conclusions Although the incidence of posterior reversible encephalopathy syndrome was high in patients with Eclampsia, nearly 20% of the patients with preEclampsia with neurologic symptoms also experienced posterior reversible encephalopathy syndrome. The similarities in clinical and radiologic findings of posterior reversible encephalopathy syndrome between the 2 groups support the hypothesis that these 2 patient groups have a shared pathophysiologic background. Thus, magnetic resonance imaging studies should be considered for patients with the recent onset of neurologic symptoms, regardless of the development of Eclampsia.
Nishant Kumar - One of the best experts on this subject based on the ideXlab platform.
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Atypical presentation of posterior reversible encephalopathy syndrome: Two cases
Journal of anaesthesiology clinical pharmacology, 2018Co-Authors: Nishant Kumar, Ranju Singh, Neha Sharma, Aruna JainAbstract:Posterior reversible encephalopathy syndrome (PRES) is a clinico-neuroradiological entity, first described in 1996. It is commonly associated with systemic hypertension, intake of immunosuppressant drugs, sepsis and Eclampsia and preEclampsia. Headache, alteration in consciousness, visual disturbances and seizures are common manifestations of PRES. Signs of pyramidal tract involvement and motor dysfunction are uncommon clinical findings. However, clinical presentation is not diagnostic. On neuroimaging, lesions are characteristically found in parieto occipital region of the brain due to vasogenic edema. We report two cases of PRES with atypical clinical presentation-one which was suggestive of neurocysticercosis and the other in which agitation and opisthotonic posture were predominant features.
Yasuyuki Kishigami - One of the best experts on this subject based on the ideXlab platform.
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Incidence of posterior reversible encephalopathy syndrome in eclamptic and patients with preEclampsia with neurologic symptoms
American journal of obstetrics and gynecology, 2016Co-Authors: Michinori Mayama, Kaname Uno, Sho Tano, Masato Yoshihara, Mayu Ukai, Yasuyuki Kishigami, Yasuhiro Ito, Hidenori OguchiAbstract:Background Posterior reversible encephalopathy syndrome is observed frequently in patients with Eclampsia; however, it has also been reported in some patients with preEclampsia. Objectives The aim of this study was to determine the incidence of posterior reversible encephalopathy syndrome in patients with preEclampsia and Eclampsia and to assess whether these 2 patient groups share similar pathophysiologic backgrounds by comparing clinical and radiologic characteristics. Study Design This was a retrospective cohort study of 4849 pregnant patients. A total of 49 patients with Eclampsia and preEclampsia and with neurologic symptoms underwent magnetic resonance imaging and magnetic resonance angiography; 10 patients were excluded from further analysis because of a history of epilepsy or dissociative disorder. The age, parity, blood pressure, and routine laboratory data at the onset of symptoms were also recorded. Results Among 39 patients with neurologic symptoms, 12 of 13 patients with Eclampsia (92.3%) and 5 of 26 patients with preEclampsia (19.2%) experienced the development of posterior reversible encephalopathy syndrome. Whereas age and blood pressure at onset were not significantly different between patients with and without encephalopathy, hematocrit, serum creatinine, aspartate transaminase, alanine transaminase, and lactate dehydrogenase values were significantly higher in patients with posterior reversible encephalopathy syndrome than in those without magnetic resonance imaging abnormalities. In contrast, patients with Eclampsia with posterior reversible encephalopathy syndrome did not show any significant differences in clinical and laboratory data compared with patients with preEclampsia with posterior reversible encephalopathy syndrome. In addition to the parietooccipital regions, atypical regions (such as the frontal and temporal lobes), and basal ganglia were also involved in patients with Eclampsia and patients with preEclampsia with posterior reversible encephalopathy syndrome. Finally, intraparenchymal hemorrhage was detected in 1 patient with Eclampsia, and subarachnoid hemorrhage was observed in 1 patient with preEclampsia. Conclusions Although the incidence of posterior reversible encephalopathy syndrome was high in patients with Eclampsia, nearly 20% of the patients with preEclampsia with neurologic symptoms also experienced posterior reversible encephalopathy syndrome. The similarities in clinical and radiologic findings of posterior reversible encephalopathy syndrome between the 2 groups support the hypothesis that these 2 patient groups have a shared pathophysiologic background. Thus, magnetic resonance imaging studies should be considered for patients with the recent onset of neurologic symptoms, regardless of the development of Eclampsia.
