The Experts below are selected from a list of 104343 Experts worldwide ranked by ideXlab platform
John F Alksne - One of the best experts on this subject based on the ideXlab platform.
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idiopathic normal pressure hydrocephalus may be a two hit disease benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood
Journal of Magnetic Resonance Imaging, 2006Co-Authors: William G. Bradley, Gautam Bahl, John F AlksneAbstract:PURPOSE: To determine if normal pressure hydrocephalus (NPH) could result from decreased resorption of cerebrospinal fluid (CSF) by the arachnoidal villi, leading to benign external hydrocephalus [BEH] in infancy, followed by deep white matter ischemia (DWMI) in late adulthood (the more hydrophilic environment increasing resistance to CSF flow through the extracellular space (ECS) of the brain). MATERIALS AND METHODS: CSF outflow via the fourth ventricle and the ECS of the brain was mathematically modeled using a parallel Electrical Circuit analog. The apparent diffusion coefficient (ADC) was measured as a surrogate of the amount of water in the ECS in normals, patients with symptomatic NPH, and patients with dilated ventricles without symptoms of NPH ("pre-NPH"). RESULTS: The Electrical Circuit model demonstrates increasing ventricular volume with increasing resistance to flow through the ECS of the brain. ADC measurements performed in the centrum semiovale are significantly higher in patients with NPH and "pre-NPH" than in age-matched controls (P<0.05), controlling for the same degree of DWMI indicating increased fluid in the ECS of the brain. CONCLUSION: The Electrical Circuit analog and finding of increased periventricular ADC support the theory that NPH is a "two hit" disease.
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idiopathic normal pressure hydrocephalus may be a two hit disease benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood
Journal of Magnetic Resonance Imaging, 2006Co-Authors: William G. Bradley, Gautam Bahl, John F AlksneAbstract:Purpose To determine if normal pressure hydrocephalus (NPH) could result from decreased resorption of cerebrospinal fluid (CSF) by the arachnoidal villi, leading to benign external hydrocephalus [BEH] in infancy, followed by deep white matter ischemia (DWMI) in late adulthood (the more hydrophilic environment increasing resistance to CSF flow through the extracellular space (ECS) of the brain). Materials and Methods CSF outflow via the fourth ventricle and the ECS of the brain was mathematically modeled using a parallel Electrical Circuit analog. The apparent diffusion coefficient (ADC) was measured as a surrogate of the amount of water in the ECS in normals, patients with symptomatic NPH, and patients with dilated ventricles without symptoms of NPH (“pre-NPH”). Results The Electrical Circuit model demonstrates increasing ventricular volume with increasing resistance to flow through the ECS of the brain. ADC measurements performed in the centrum semiovale are significantly higher in patients with NPH and “pre-NPH” than in age-matched controls (P < 0.05), controlling for the same degree of DWMI indicating increased fluid in the ECS of the brain. Conclusion The Electrical Circuit analog and finding of increased periventricular ADC support the theory that NPH is a “two hit” disease. J. Magn. Reson. Imaging 2006. © 2006 Wiley-Liss, Inc.
William G. Bradley - One of the best experts on this subject based on the ideXlab platform.
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idiopathic normal pressure hydrocephalus may be a two hit disease benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood
Journal of Magnetic Resonance Imaging, 2006Co-Authors: William G. Bradley, Gautam Bahl, John F AlksneAbstract:PURPOSE: To determine if normal pressure hydrocephalus (NPH) could result from decreased resorption of cerebrospinal fluid (CSF) by the arachnoidal villi, leading to benign external hydrocephalus [BEH] in infancy, followed by deep white matter ischemia (DWMI) in late adulthood (the more hydrophilic environment increasing resistance to CSF flow through the extracellular space (ECS) of the brain). MATERIALS AND METHODS: CSF outflow via the fourth ventricle and the ECS of the brain was mathematically modeled using a parallel Electrical Circuit analog. The apparent diffusion coefficient (ADC) was measured as a surrogate of the amount of water in the ECS in normals, patients with symptomatic NPH, and patients with dilated ventricles without symptoms of NPH ("pre-NPH"). RESULTS: The Electrical Circuit model demonstrates increasing ventricular volume with increasing resistance to flow through the ECS of the brain. ADC measurements performed in the centrum semiovale are significantly higher in patients with NPH and "pre-NPH" than in age-matched controls (P<0.05), controlling for the same degree of DWMI indicating increased fluid in the ECS of the brain. CONCLUSION: The Electrical Circuit analog and finding of increased periventricular ADC support the theory that NPH is a "two hit" disease.
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idiopathic normal pressure hydrocephalus may be a two hit disease benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood
Journal of Magnetic Resonance Imaging, 2006Co-Authors: William G. Bradley, Gautam Bahl, John F AlksneAbstract:Purpose To determine if normal pressure hydrocephalus (NPH) could result from decreased resorption of cerebrospinal fluid (CSF) by the arachnoidal villi, leading to benign external hydrocephalus [BEH] in infancy, followed by deep white matter ischemia (DWMI) in late adulthood (the more hydrophilic environment increasing resistance to CSF flow through the extracellular space (ECS) of the brain). Materials and Methods CSF outflow via the fourth ventricle and the ECS of the brain was mathematically modeled using a parallel Electrical Circuit analog. The apparent diffusion coefficient (ADC) was measured as a surrogate of the amount of water in the ECS in normals, patients with symptomatic NPH, and patients with dilated ventricles without symptoms of NPH (“pre-NPH”). Results The Electrical Circuit model demonstrates increasing ventricular volume with increasing resistance to flow through the ECS of the brain. ADC measurements performed in the centrum semiovale are significantly higher in patients with NPH and “pre-NPH” than in age-matched controls (P < 0.05), controlling for the same degree of DWMI indicating increased fluid in the ECS of the brain. Conclusion The Electrical Circuit analog and finding of increased periventricular ADC support the theory that NPH is a “two hit” disease. J. Magn. Reson. Imaging 2006. © 2006 Wiley-Liss, Inc.
Gautam Bahl - One of the best experts on this subject based on the ideXlab platform.
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idiopathic normal pressure hydrocephalus may be a two hit disease benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood
Journal of Magnetic Resonance Imaging, 2006Co-Authors: William G. Bradley, Gautam Bahl, John F AlksneAbstract:PURPOSE: To determine if normal pressure hydrocephalus (NPH) could result from decreased resorption of cerebrospinal fluid (CSF) by the arachnoidal villi, leading to benign external hydrocephalus [BEH] in infancy, followed by deep white matter ischemia (DWMI) in late adulthood (the more hydrophilic environment increasing resistance to CSF flow through the extracellular space (ECS) of the brain). MATERIALS AND METHODS: CSF outflow via the fourth ventricle and the ECS of the brain was mathematically modeled using a parallel Electrical Circuit analog. The apparent diffusion coefficient (ADC) was measured as a surrogate of the amount of water in the ECS in normals, patients with symptomatic NPH, and patients with dilated ventricles without symptoms of NPH ("pre-NPH"). RESULTS: The Electrical Circuit model demonstrates increasing ventricular volume with increasing resistance to flow through the ECS of the brain. ADC measurements performed in the centrum semiovale are significantly higher in patients with NPH and "pre-NPH" than in age-matched controls (P<0.05), controlling for the same degree of DWMI indicating increased fluid in the ECS of the brain. CONCLUSION: The Electrical Circuit analog and finding of increased periventricular ADC support the theory that NPH is a "two hit" disease.
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idiopathic normal pressure hydrocephalus may be a two hit disease benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood
Journal of Magnetic Resonance Imaging, 2006Co-Authors: William G. Bradley, Gautam Bahl, John F AlksneAbstract:Purpose To determine if normal pressure hydrocephalus (NPH) could result from decreased resorption of cerebrospinal fluid (CSF) by the arachnoidal villi, leading to benign external hydrocephalus [BEH] in infancy, followed by deep white matter ischemia (DWMI) in late adulthood (the more hydrophilic environment increasing resistance to CSF flow through the extracellular space (ECS) of the brain). Materials and Methods CSF outflow via the fourth ventricle and the ECS of the brain was mathematically modeled using a parallel Electrical Circuit analog. The apparent diffusion coefficient (ADC) was measured as a surrogate of the amount of water in the ECS in normals, patients with symptomatic NPH, and patients with dilated ventricles without symptoms of NPH (“pre-NPH”). Results The Electrical Circuit model demonstrates increasing ventricular volume with increasing resistance to flow through the ECS of the brain. ADC measurements performed in the centrum semiovale are significantly higher in patients with NPH and “pre-NPH” than in age-matched controls (P < 0.05), controlling for the same degree of DWMI indicating increased fluid in the ECS of the brain. Conclusion The Electrical Circuit analog and finding of increased periventricular ADC support the theory that NPH is a “two hit” disease. J. Magn. Reson. Imaging 2006. © 2006 Wiley-Liss, Inc.
T K Dong - One of the best experts on this subject based on the ideXlab platform.
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dynamic modeling of li ion batteries using an equivalent Electrical Circuit
Journal of The Electrochemical Society, 2011Co-Authors: T K Dong, A Kirchev, F Mattera, Julia Kowal, Yann BultelAbstract:The modeling of Li-ion batteries may work as a powerful tool for the introduction and widespread testing of this technology in alternative energy storage, hybrid, and electric vehicle applications. In this paper, the authors propose a model for Li-ion batteries that is based on a typical equivalent Electrical Circuit (EEC) representation of these batteries and valid over a wide frequency range (2 mHz―65 kHz). However, a full parameterization of EEC models was not possible only with the electrochemical impedance spectroscopy (EIS) method, particularly at high charge/discharge currents. Therefore, a method combining EIS and charge/ discharge curves analysis has been developed. The simulated and experimental results were compared, and it was demonstrated that the developed method provides accurate predictions of the dynamic behavior of Li-ion batteries over wide state of charge and charge/discharge current range.
Yann Bultel - One of the best experts on this subject based on the ideXlab platform.
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dynamic modeling of li ion batteries using an equivalent Electrical Circuit
Journal of The Electrochemical Society, 2011Co-Authors: T K Dong, A Kirchev, F Mattera, Julia Kowal, Yann BultelAbstract:The modeling of Li-ion batteries may work as a powerful tool for the introduction and widespread testing of this technology in alternative energy storage, hybrid, and electric vehicle applications. In this paper, the authors propose a model for Li-ion batteries that is based on a typical equivalent Electrical Circuit (EEC) representation of these batteries and valid over a wide frequency range (2 mHz―65 kHz). However, a full parameterization of EEC models was not possible only with the electrochemical impedance spectroscopy (EIS) method, particularly at high charge/discharge currents. Therefore, a method combining EIS and charge/ discharge curves analysis has been developed. The simulated and experimental results were compared, and it was demonstrated that the developed method provides accurate predictions of the dynamic behavior of Li-ion batteries over wide state of charge and charge/discharge current range.
