The Experts below are selected from a list of 351 Experts worldwide ranked by ideXlab platform
Stanković Dalibor - One of the best experts on this subject based on the ideXlab platform.
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Anti-human albumin monoclonal antibody immobilized on EDC-NHS functionalized carboxylic graphene/AuNPs composite as promising electrochemical HSA immunosensor
Elsevier BV, 2020Co-Authors: Stanković Vesna, Ognjanović Miloš, Antić Bratislav, Kalcher Kurt, Mutić Jelena, Đurđić Slađana, Stanković DaliborAbstract:Diagnosis and treatment of some important diseased and metabolic disorders is based on successful detection of albumin. In this work, we aim to develop a simple immunosensor for the detection of human serum albumin in biological fluids. Anti-human albumin antibody was covalently attached to the activated surface of screen-printed carbon electrodes enriched with carboxyl graphene/gold nanoparticles composite. Microstructure (TEM, FE-SEM, XRD) and electrochemical (CV, EIS) characterization methods were used to investigate composite properties and to confirm the successful modification of the electrodes. Under the optimal conditions, linear working range and limit of detection were 2.5–500 μg/mL and 1.55 μg/mL, respectively. Additionally, the effect of some possibly interfering compounds was investigated and the immunosensor was used for real sample analysis. The results showed that the sensor exhibited accurate, precise and sensitive characteristics and can be promising replacement to the convention methods for albumin detection in clinical practice.This is the peer-reviewed version of the article: Journal of Electroanalytical Chemistry, 2020, 860, 113928, doi: [https://doi.org/10.1016/j.jelechem.2020.113928]The published version: [http://cer.ihtm.bg.ac.rs/handle/123456789/3419
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Anti-human albumin monoclonal antibody immobilized on EDC-NHS functionalized carboxylic graphene/AuNPs composite as promising electrochemical HSA immunosensor
Elsevier, 2020Co-Authors: Stanković Vesna, Ognjanović Miloš, Antić Bratislav, Kalcher Kurt, Mutić Jelena, Đurđić Slađana, Stanković DaliborAbstract:Diagnosis and treatment of some important diseased and metabolic disorders is based on successful detection of albumin. In this work, we aim to develop a simple immunosensor for the detection of human serum albumin in biological fluids. Anti-human albumin antibody was covalently attached to the activated surface of screen-printed carbon electrodes enriched with carboxyl graphene/gold nanoparticles composite. Microstructure (TEM, FE-SEM, XRD) and electrochemical (CV, EIS) characterization methods were used to investigate composite properties and to confirm the successful modification of the electrodes. Under the optimal conditions, linear working range and limit of detection were 2.5–500 μg/mL and 1.55 μg/mL, respectively. Additionally, the effect of some possibly interfering compounds was investigated and the immunosensor was used for real sample analysis. The results showed that the sensor exhibited accurate, precise and sensitive characteristics and can be promising replacement to the convention methods for albumin detection in clinical practice.This is the peer-reviewed version of the article: Stanković, V.; Đurđić, S.; Ognjanović, M.; Antić, B.; Kalcher, K.; Mutić, J.; Stanković, D. M. Anti-Human Albumin Monoclonal Antibody Immobilized on EDC-NHS Functionalized Carboxylic Graphene/AuNPs Composite as Promising Electrochemical HSA Immunosensor. Journal of Electroanalytical Chemistry 2020, 860. [https://doi.org/10.1016/j.jelechem.2020.113928]Supplementary material: [http://cherry.chem.bg.ac.rs/handle/123456789/3892
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A novel nonenzymatic hydrogen peroxide amperometric sensor based on AgNp@GNR nanocomposites modified screen-printed carbon electrode
'Elsevier BV', 2020Co-Authors: Stanković Vesna, Ognjanović Miloš, Kalcher Kurt, Mutić Jelena, Đurđić Slađana, Stanković DaliborAbstract:A nonenzymatic hydrogen-peroxide sensor was developed by utilization of silver nanoparticles and graphenenanoribbons. The mentioned composite was inflicted on a screen-printed carbon electrode which provides disposable,ready-to-use sensor. The structure and morphology of the nanocomposite were analyzed by scanning electron microscopyand X-ray diffraction. The sensor has excellent performance toward H2O2 amperometric detection. Figures ofmerit include dynamic response range from 0.05 to 5 mM and detection limit of 20 μM (at S/N =3). The fabricatedsensor was used for the determination ofH2O2 in milk samples. The obtained results showed that the proposed AgNp@GNR/SPCE sensor can be used for the determination of hydrogen peroxide in real samples.This is the peer-reviewed version o the article: V. Stanković, S. Đurđić, M. Ognjanović, et al., A novel nonenzymatic hydrogen peroxide amperometric sensor based on AgNp@GNR nanocomposites modified screen-printed carbon electrode, Journal of Electroanalytical Chemistry (2020), 876, 114487, doi: [https://doi.org/10.1016/j.jelechem.2020.114487]Published version: [http://cer.ihtm.bg.ac.rs/handle/123456789/3612
Leslaw K Bieniasz - One of the best experts on this subject based on the ideXlab platform.
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a nonlinear transient reaction diffusion problem from Electroanalytical Chemistry
Siam Journal on Applied Mathematics, 2021Co-Authors: Michael Vynnycky, Sean Mckee, Leslaw K BieniaszAbstract:A nonlinear reaction-diffusion partial differential equation occurring in models of transient controlled-potential experiments in Electroanalytical Chemistry is investigated analytically and numeri...
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automatic simulation of electrochemical transients by the adaptive huber method for volterra integral equations involving kernel terms exp α t τ erex β t τ 1 2 and exp α t τ daw β t τ 1 2
Journal of Mathematical Chemistry, 2012Co-Authors: Leslaw K BieniaszAbstract:Development of fully automatic methods for the simulation of transient experiments in Electroanalytical Chemistry is a desirable element of the contemporary trends of laboratory automation in electroChemistry. In accord with this idea, the adaptive Huber method, elaborated by the present author, is intended to solve automatically integral equations of Volterra type, encountered in the theory of controlled-potential transients. The coefficients of the method have been recently obtained for integral transformation kernels involving terms K(t, τ) = exp[−α(t − τ)]erex{[β(t − τ)]1/2} and K(t, τ) = exp[−α(t − τ)]daw{[β(t − τ)]1/2} with α ≥ 0 and β ≥ 0, which are known to occur in the above integral equations. In this work the validity of the resulting method, for electrochemical simulations, is examined using representative examples of Electroanalytical models involving integral equations with various special cases of such kernel terms. The performance of the method is found similar to that previously reported for integral equations involving exclusively kernels K(t, τ) = 1, K(t, τ) = (t − τ)−1/2, and K(t, τ) = exp[−λ (t − τ)](t − τ)−1/2 with λ > 0.
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extension of the adaptive huber method for volterra integral equations arising in Electroanalytical Chemistry to convolution kernels exp α t τ erex β t τ 1 2 and exp α t τ daw β t τ 1 2
Journal of Computational Methods in Sciences and Engineering archive, 2011Co-Authors: Leslaw K BieniaszAbstract:Integral transformation kernels having convolution forms exp[-α(t -τ)]erex{[β(t - τ)]1/2} and exp[-α(t- τ)]daw{⌊β(t - τ)⌋1/2}, where erex(z) = exp(z2)erfc(z), daw(z) is the Dawson integral, and α ≥ 0 and β ≥ 0, occur in integral equations of Volterra type, pertinent to Electroanalytical Chemistry. An ability to solve this sort of integral equations has been added to the recently developed adaptive Huber method. Relevant formulae for the method coefficients are reported, and computational tests of the convergence and numerical stability of the method for these kernels are presented. Practical accuracy orders are close to 2. In cases when integral equations contain contributions from the kernel exp⌊- α(t - τ)⌋daw{[β(t - τ)]1/2}, such that the total kernels are increasing functions of t -τ, the method may become unstable. In cases when α > 0, β > 0, β/α ≫ 1 and integration steps are very small, β/α cannot exceed a certain threshold due to machine precision. Similarly, in the case of kernel exp[-α(t - τ)]erex{⌊β(t -τ)⌋l/2}, when α > 0, β > 0, α ≠ β, but α is very close to β, |β/α -1| cannot be smaller than a certain threshold.
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cyclic voltammetric current functions determined with a prescribed accuracy by the adaptive huber method for abel integral equations
Analytical Chemistry, 2008Co-Authors: Leslaw K BieniaszAbstract:Modern Electroanalytical applications of cyclic voltammetry require that theoretical current functions be obtainable automatically, efficiently, and with a prescribed accuracy, by computer simulation algorithms. One of the classical simulation approaches relies on formulating and solving relevant integral equations. Numerical solution methods, used for this purpose so far, are nonautomatic and do not provide information about accuracy of the results. The adaptive variant of the Huber method, developed by the present author, can generate theoretical cyclic voltammograms automatically, with a given target accuracy, and more efficiently than the formerly studied patch-adaptive direct simulation method. This is demonstrated using examples of cyclic voltammograms described by the first-kind Abel integral equations. The method is therefore a candidate for automatic integral equation solvers, needed for building a new generation of problem solving environments for Electroanalytical Chemistry and for widely under...
Daniel Mandler - One of the best experts on this subject based on the ideXlab platform.
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applications of self assembled monolayers in Electroanalytical Chemistry
Electroanalysis, 1996Co-Authors: Daniel Mandler, Iva TuryanAbstract:The different approaches in which self-assembled monolayers (SAMs) have been applied in Electroanalytical Chemistry are reviewed. Three principal concepts have been used and can be categorized according to the mechanism of attachment of the monolayer to the electrode. These include the formation of covalent bonds between reactive organic molecules, such as chlorosilanes, with activated surfaces, the formation of lipid and bilayer lipid membranes that self-assemble on conductive surfaces and the adsorption of functionalized alkanes, e.g., alkanethiols, on well ordered surfaces. Systems for detecting inorganic, organic and biological species are described and conclusions are drawn.
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self assembled monolayers in Electroanalytical Chemistry application of omega mercaptocarboxylic acid monolayers for electrochemical determination of ultralow levels of cadmium ii
Analytical Chemistry, 1994Co-Authors: Iva Turyan, Daniel MandlerAbstract:Self-assembled monolayers of ω-mercaptocarboxylic acids, HS(CH 2 ) n H (n=1, 2, 5, 10), on mercury film (MF) and gold electrodes have been used for the very sensitive and selective analysis of ultralow levels of cadmium(II). We find that shorter ω-mercaptocarboxylic acids provide superior sensitivity. Other parameters that govern the sensitivity and selectivity of this system have been examined in detail. Optimizing these factors resulted in a detection limit of 4×10 -12 M (0.45 ppt)
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self assembled monolayers in Electroanalytical Chemistry application of omega mercapto carboxylic acid monolayers for the electrochemical detection of dopamine in the presence of a high concentration of ascorbic acid
Analytical Chemistry, 1993Co-Authors: Franck Malem, Daniel MandlerAbstract:Self-assembled monolayers of ω-mercapto carboxylic acids, HS(CH 2 ) n CO 2 H (n=2, 5, 10), C n , on gold electrodes were used as a means to induce electrochemical differentiation between a neurotransmitter, dopamine (DO), and ascorbic acid (AA). Optimum differentiation is found for n=5, and it is attributed a compromise between as well-organized system that requires long ω-mercapto carboxylic acids and a reasonable rate of electron transfer which is observed with short ω-mercapto carboxylic acids
Shuang Han - One of the best experts on this subject based on the ideXlab platform.
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recent development of carbon electrode materials and their bioanalytical and environmental applications
Chemical Society Reviews, 2016Co-Authors: Wei Zhang, Shuyun Zhu, Rafael Luque, Shuang HanAbstract:Carbon materials have been extensively investigated due to their diversity, favorable properties, and active applications including Electroanalytical Chemistry. This critical review discusses new synthetic methods, novel carbon materials, new properties and Electroanalytical applications of carbon materials particularly related to the preparation as well as bioanalytical and environmental applications of highly oriented pyrolytic graphite, graphene, carbon nanotubes, various carbon films (e.g. pyrolyzed carbon films, boron-doped diamond films and diamond-like carbon films) and screen printing carbon electrodes. Future perspectives in the field have also been discussed (366 references).
Rafael Luque - One of the best experts on this subject based on the ideXlab platform.
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recent development of carbon electrode materials and their bioanalytical and environmental applications
Chemical Society Reviews, 2016Co-Authors: Wei Zhang, Shuyun Zhu, Rafael Luque, Shuang HanAbstract:Carbon materials have been extensively investigated due to their diversity, favorable properties, and active applications including Electroanalytical Chemistry. This critical review discusses new synthetic methods, novel carbon materials, new properties and Electroanalytical applications of carbon materials particularly related to the preparation as well as bioanalytical and environmental applications of highly oriented pyrolytic graphite, graphene, carbon nanotubes, various carbon films (e.g. pyrolyzed carbon films, boron-doped diamond films and diamond-like carbon films) and screen printing carbon electrodes. Future perspectives in the field have also been discussed (366 references).