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Nicola S. Logan - One of the best experts on this subject based on the ideXlab platform.

  • Shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative Ophthalmology & Visual Science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE: To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS: Both eyes of 55 adult subjects were studied, 27 with Emmetropia (mean spherical error [MSE] ≥ -0.55;

  • shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative Ophthalmology & Visual Science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE: To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS: Both eyes of 55 adult subjects were studied, 27 with Emmetropia (mean spherical error [MSE] ≥ -0.55; <+0.75 D; mean +0.09 ± 0.36 D) and 28 with myopia (MSE -5.87 ± 2.31 D). Cycloplegic refraction was measured with a Shin Nippon autorefractor and anterior chamber depth and axial length with a Zeiss IOLMaster. Posterior vitreous chamber shapes were determined from T2-weighted magnetic resonance imaging (3.0-T) using procedures previously reported by our laboratory. Three-dimensional surface model coordinates were assigned to nasal, temporal, superior, and inferior quadrants and plotted in two dimensions to illustrate the composite shape of respective quadrants posterior to the second nodal point. Spherical analogues of chamber shape were constructed to compare relative sphericity between refractive groups and quadrants. RESULTS: Differences in shape occurred in the region posterior to points of maximum globe width and were thus in general accord with an equatorial model of myopic expansion. Shape in Emmetropia is categorized distinctly as that of an oblate ellipse and in myopia as an oblate ellipse of significantly less degree such that it approximates to a sphere. There was concordance between shape and retinotopic projection of respective quadrants into right, left, superior, and inferior visual fields. CONCLUSIONS: Prolate ellipse posterior chamber shapes were rarely found in myopia, and we propose that spherical shape in myopia may constitute a biomechanical limitation on further axial elongation. Synchronization of quadrant shapes with retinotopic projection suggests that binocular growth is coordinated by processes that operate beyond the optic chiasm.

  • Shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative ophthalmology & visual science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE - To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS - Both eyes of 55 adult subjects were studied, 27 with Emmetropia (MSE =-0.55;

  • shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative Ophthalmology & Visual Science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE - To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS - Both eyes of 55 adult subjects were studied, 27 with Emmetropia (MSE =-0.55; <+0.75D; mean +0.09 ±0.36D) and 28 with myopia (MSE -5.87 ±2.31D). Cycloplegic refraction was measured with a Shin Nippon autorefractor and anterior chamber depth and axial length with a Zeiss IOLMaster. Posterior vitreous chamber shapes were determined from T2-weighted MRI (3-Tesla) using procedures previously reported by our laboratory. 3-D surface model coordinates were assigned to nasal, temporal, superior and inferior quadrants and plotted in 2-D to illustrate the composite shape of respective quadrants posterior to the second nodal point. Spherical analogues of chamber shape were constructed to compare relative sphericity between refractive groups and quadrants. RESULTS - Differences in shape occurred in the region posterior to points of maximum globe width and were thus in general accord with an equatorial model of myopic expansion. Shape in Emmetropia is categorised distinctly as that of an oblate ellipse and in myopia as an oblate ellipse of significantly less degree such that it approximates to a sphere. There was concordance between shape and retinotopic projection of respective quadrants into right, left, superior and inferior visual fields. CONCLUSIONS - The transition in shape from oblate ellipse to sphere with axial elongation supports the hypothesis that myopia may be a consequence of equatorial restriction associated with biomechanical anomalies of the ciliary apparatus. The synchronisation of quadrant shapes with retinotopic projection suggests that binocular growth is coordinated by processes that operate beyond the optic chiasm.

Bernard Gilmartin - One of the best experts on this subject based on the ideXlab platform.

  • Shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative Ophthalmology & Visual Science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE: To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS: Both eyes of 55 adult subjects were studied, 27 with Emmetropia (mean spherical error [MSE] ≥ -0.55;

  • shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative Ophthalmology & Visual Science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE: To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS: Both eyes of 55 adult subjects were studied, 27 with Emmetropia (mean spherical error [MSE] ≥ -0.55; <+0.75 D; mean +0.09 ± 0.36 D) and 28 with myopia (MSE -5.87 ± 2.31 D). Cycloplegic refraction was measured with a Shin Nippon autorefractor and anterior chamber depth and axial length with a Zeiss IOLMaster. Posterior vitreous chamber shapes were determined from T2-weighted magnetic resonance imaging (3.0-T) using procedures previously reported by our laboratory. Three-dimensional surface model coordinates were assigned to nasal, temporal, superior, and inferior quadrants and plotted in two dimensions to illustrate the composite shape of respective quadrants posterior to the second nodal point. Spherical analogues of chamber shape were constructed to compare relative sphericity between refractive groups and quadrants. RESULTS: Differences in shape occurred in the region posterior to points of maximum globe width and were thus in general accord with an equatorial model of myopic expansion. Shape in Emmetropia is categorized distinctly as that of an oblate ellipse and in myopia as an oblate ellipse of significantly less degree such that it approximates to a sphere. There was concordance between shape and retinotopic projection of respective quadrants into right, left, superior, and inferior visual fields. CONCLUSIONS: Prolate ellipse posterior chamber shapes were rarely found in myopia, and we propose that spherical shape in myopia may constitute a biomechanical limitation on further axial elongation. Synchronization of quadrant shapes with retinotopic projection suggests that binocular growth is coordinated by processes that operate beyond the optic chiasm.

  • Shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative ophthalmology & visual science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE - To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS - Both eyes of 55 adult subjects were studied, 27 with Emmetropia (MSE =-0.55;

  • shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative Ophthalmology & Visual Science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE - To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS - Both eyes of 55 adult subjects were studied, 27 with Emmetropia (MSE =-0.55; <+0.75D; mean +0.09 ±0.36D) and 28 with myopia (MSE -5.87 ±2.31D). Cycloplegic refraction was measured with a Shin Nippon autorefractor and anterior chamber depth and axial length with a Zeiss IOLMaster. Posterior vitreous chamber shapes were determined from T2-weighted MRI (3-Tesla) using procedures previously reported by our laboratory. 3-D surface model coordinates were assigned to nasal, temporal, superior and inferior quadrants and plotted in 2-D to illustrate the composite shape of respective quadrants posterior to the second nodal point. Spherical analogues of chamber shape were constructed to compare relative sphericity between refractive groups and quadrants. RESULTS - Differences in shape occurred in the region posterior to points of maximum globe width and were thus in general accord with an equatorial model of myopic expansion. Shape in Emmetropia is categorised distinctly as that of an oblate ellipse and in myopia as an oblate ellipse of significantly less degree such that it approximates to a sphere. There was concordance between shape and retinotopic projection of respective quadrants into right, left, superior and inferior visual fields. CONCLUSIONS - The transition in shape from oblate ellipse to sphere with axial elongation supports the hypothesis that myopia may be a consequence of equatorial restriction associated with biomechanical anomalies of the ciliary apparatus. The synchronisation of quadrant shapes with retinotopic projection suggests that binocular growth is coordinated by processes that operate beyond the optic chiasm.

Seyed Ali Tabatabaei - One of the best experts on this subject based on the ideXlab platform.

  • comparison of retinal nerve fiber layer profile in subjects with myopia and Emmetropia using scanning laser polarimetry
    Iranian Journal of Ophthalmology, 2013
    Co-Authors: Reza Zarei, Ramin Daneshvar, Mohammad Soleimani, Mohammad Razzaghi, Heidar Amini, Masoud Mohammadi, Sasan Moghimi, Yadollah Eslami, Ghasem Fakhraie, Seyed Ali Tabatabaei
    Abstract:

    Purpose To compare retinal nerve fiber layer (RNFL) profile in subjects with myopia and Emmetropia using GDx variable corneal compensator (VCC) Methods Besides ophthalmologic standard examination (refraction, visual acuity and slit-lamp examination, applanation tonometry, and funduscopy), perimetry and scanning laser polarimetry (SLP) were performed. 171 healthy age-matched subjects with low to high myopia (90 subjects) and Emmetropia (81 subjects) underwent RNFL analysis by means of GDx VCC. The mean value of each parameter was compared in myopic and emmetropic eyes. Results Mean myopia was 3.43±1.19 diopter (D) (range, -0.50 to -6.50). Except for ratio parameters, RNFL parameters were significantly lower in myopic patients. TNSIT standard deviation (p=0.026), nerve fiber indicator (NFI) (p=0.027), superior/nasal (pConclusion RNFL thicknesses gradually decreased with increasing age in myopic patients. Patients with myopia had significantly lower RNFL thickness than normal subjects and, although weakened by wide age range of myopic group, there was a linear negative correlation between severity of myopia and RNFL thickness in myopic patients.

Manbir Nagra - One of the best experts on this subject based on the ideXlab platform.

  • Shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative Ophthalmology & Visual Science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE: To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS: Both eyes of 55 adult subjects were studied, 27 with Emmetropia (mean spherical error [MSE] ≥ -0.55;

  • shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative Ophthalmology & Visual Science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE: To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS: Both eyes of 55 adult subjects were studied, 27 with Emmetropia (mean spherical error [MSE] ≥ -0.55; <+0.75 D; mean +0.09 ± 0.36 D) and 28 with myopia (MSE -5.87 ± 2.31 D). Cycloplegic refraction was measured with a Shin Nippon autorefractor and anterior chamber depth and axial length with a Zeiss IOLMaster. Posterior vitreous chamber shapes were determined from T2-weighted magnetic resonance imaging (3.0-T) using procedures previously reported by our laboratory. Three-dimensional surface model coordinates were assigned to nasal, temporal, superior, and inferior quadrants and plotted in two dimensions to illustrate the composite shape of respective quadrants posterior to the second nodal point. Spherical analogues of chamber shape were constructed to compare relative sphericity between refractive groups and quadrants. RESULTS: Differences in shape occurred in the region posterior to points of maximum globe width and were thus in general accord with an equatorial model of myopic expansion. Shape in Emmetropia is categorized distinctly as that of an oblate ellipse and in myopia as an oblate ellipse of significantly less degree such that it approximates to a sphere. There was concordance between shape and retinotopic projection of respective quadrants into right, left, superior, and inferior visual fields. CONCLUSIONS: Prolate ellipse posterior chamber shapes were rarely found in myopia, and we propose that spherical shape in myopia may constitute a biomechanical limitation on further axial elongation. Synchronization of quadrant shapes with retinotopic projection suggests that binocular growth is coordinated by processes that operate beyond the optic chiasm.

  • Shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative ophthalmology & visual science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE - To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS - Both eyes of 55 adult subjects were studied, 27 with Emmetropia (MSE =-0.55;

  • shape of the posterior vitreous chamber in human Emmetropia and myopia
    Investigative Ophthalmology & Visual Science, 2013
    Co-Authors: Bernard Gilmartin, Manbir Nagra, Nicola S. Logan
    Abstract:

    PURPOSE - To compare posterior vitreous chamber shape in myopia to that in Emmetropia. METHODS - Both eyes of 55 adult subjects were studied, 27 with Emmetropia (MSE =-0.55; <+0.75D; mean +0.09 ±0.36D) and 28 with myopia (MSE -5.87 ±2.31D). Cycloplegic refraction was measured with a Shin Nippon autorefractor and anterior chamber depth and axial length with a Zeiss IOLMaster. Posterior vitreous chamber shapes were determined from T2-weighted MRI (3-Tesla) using procedures previously reported by our laboratory. 3-D surface model coordinates were assigned to nasal, temporal, superior and inferior quadrants and plotted in 2-D to illustrate the composite shape of respective quadrants posterior to the second nodal point. Spherical analogues of chamber shape were constructed to compare relative sphericity between refractive groups and quadrants. RESULTS - Differences in shape occurred in the region posterior to points of maximum globe width and were thus in general accord with an equatorial model of myopic expansion. Shape in Emmetropia is categorised distinctly as that of an oblate ellipse and in myopia as an oblate ellipse of significantly less degree such that it approximates to a sphere. There was concordance between shape and retinotopic projection of respective quadrants into right, left, superior and inferior visual fields. CONCLUSIONS - The transition in shape from oblate ellipse to sphere with axial elongation supports the hypothesis that myopia may be a consequence of equatorial restriction associated with biomechanical anomalies of the ciliary apparatus. The synchronisation of quadrant shapes with retinotopic projection suggests that binocular growth is coordinated by processes that operate beyond the optic chiasm.

Reza Zarei - One of the best experts on this subject based on the ideXlab platform.

  • comparison of retinal nerve fiber layer profile in subjects with myopia and Emmetropia using scanning laser polarimetry
    Iranian Journal of Ophthalmology, 2013
    Co-Authors: Reza Zarei, Ramin Daneshvar, Mohammad Soleimani, Mohammad Razzaghi, Heidar Amini, Masoud Mohammadi, Sasan Moghimi, Yadollah Eslami, Ghasem Fakhraie, Seyed Ali Tabatabaei
    Abstract:

    Purpose To compare retinal nerve fiber layer (RNFL) profile in subjects with myopia and Emmetropia using GDx variable corneal compensator (VCC) Methods Besides ophthalmologic standard examination (refraction, visual acuity and slit-lamp examination, applanation tonometry, and funduscopy), perimetry and scanning laser polarimetry (SLP) were performed. 171 healthy age-matched subjects with low to high myopia (90 subjects) and Emmetropia (81 subjects) underwent RNFL analysis by means of GDx VCC. The mean value of each parameter was compared in myopic and emmetropic eyes. Results Mean myopia was 3.43±1.19 diopter (D) (range, -0.50 to -6.50). Except for ratio parameters, RNFL parameters were significantly lower in myopic patients. TNSIT standard deviation (p=0.026), nerve fiber indicator (NFI) (p=0.027), superior/nasal (pConclusion RNFL thicknesses gradually decreased with increasing age in myopic patients. Patients with myopia had significantly lower RNFL thickness than normal subjects and, although weakened by wide age range of myopic group, there was a linear negative correlation between severity of myopia and RNFL thickness in myopic patients.