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Puja B. Parikh - One of the best experts on this subject based on the ideXlab platform.

Andrew C. Glatz - One of the best experts on this subject based on the ideXlab platform.

  • relation of left ventricular End Diastolic Pressure to right ventricular End Diastolic volume after operative treatment of tetralogy of fallot
    American Journal of Cardiology, 2012
    Co-Authors: Matthew C. Schwartz, Jonathan J. Rome, Matthew J. Gillespie, Kevin K. Whitehead, Matthew A. Harris, Mark A. Fogel, Andrew C. Glatz
    Abstract:

    Left ventricular (LV) Diastolic dysfunction is associated with poor outcomes after tetralogy of Fallot (TOF) repair, although its cause is not known, and its relation to right ventricular (RV) performance has never been examined. The aim of this study was to test the hypothesis that RV dilation leads to LV Diastolic dysfunction after TOF repair. Patients with repaired TOF who underwent cardiac catheterization and cardiac magnetic resonance imaging within 6 months from January 2003 and April 2011 were reviewed to assess the relation of LV End-Diastolic Pressure (LVEDP) and indexed RV End-Diastolic volume (RVEDVi). Thirty-eight patients were included at a median age of 10.1 years (range 0.6 to 54.7). There was a significant linear association between RVEDVi and LVEDP (p = 0.05). RV End-Diastolic Pressure (p <0.001), right pulmonary artery systolic Pressure (p = 0.009), left pulmonary artery systolic Pressure (p = 0.02), and total cardiopulmonary support time (p = 0.04) during TOF repair were also significantly associated with LVEDP. Compared to patients with LVEDP <12 mm Hg, those with LVEDP ≥12 mm Hg had significantly higher mean RVEDVi (135.2 ± 47.8 vs 98.6 ± 28 ml/m(2), p = 0.007) and mean RV End-Diastolic Pressure (11.7 ± 1.6 vs 8.5 ± 2.8 mm Hg, p = 0.0003). In conclusion, after TOF repair, LVEDP is significantly associated with RVEDVi. Furthermore, mean RVEDVi is significantly higher in patients with LVEDP ≥12 mm Hg. These findings support the theory that RV dilation may impair LV Diastolic function and that LV parameters may also be important to consider in determining timing of pulmonary valve replacement.

  • Relation of left ventricular End Diastolic Pressure to right ventricular End Diastolic volume after operative treatment of tetralogy of fallot.
    The American journal of cardiology, 2011
    Co-Authors: Matthew C. Schwartz, Jonathan J. Rome, Matthew J. Gillespie, Kevin K. Whitehead, Matthew A. Harris, Mark A. Fogel, Andrew C. Glatz
    Abstract:

    Left ventricular (LV) Diastolic dysfunction is associated with poor outcomes after tetralogy of Fallot (TOF) repair, although its cause is not known, and its relation to right ventricular (RV) performance has never been examined. The aim of this study was to test the hypothesis that RV dilation leads to LV Diastolic dysfunction after TOF repair. Patients with repaired TOF who underwent cardiac catheterization and cardiac magnetic resonance imaging within 6 months from January 2003 and April 2011 were reviewed to assess the relation of LV End-Diastolic Pressure (LVEDP) and indexed RV End-Diastolic volume (RVEDVi). Thirty-eight patients were included at a median age of 10.1 years (range 0.6 to 54.7). There was a significant linear association between RVEDVi and LVEDP (p = 0.05). RV End-Diastolic Pressure (p

  • Abstract 12799: Left Ventricular End-Diastolic Pressure Correlates with Right Ventricular End-Diastolic Volume in Patients Following Tetralogy of Fallot Repair
    Circulation, 2010
    Co-Authors: Matthew C. Schwartz, Jonathan J. Rome, Matthew A. Harris, Mark C Fogel, Andrew C. Glatz
    Abstract:

    Introduction: Right ventricular dilation is a long-term complication after tetralogy of Fallot (TOF) repair and is associated with poor outcomes. Left ventricular End-Diastolic Pressure (LVEDP) ≥12...

Luis Gruberg - One of the best experts on this subject based on the ideXlab platform.

Allen Jeremias - One of the best experts on this subject based on the ideXlab platform.

Matthew C. Schwartz - One of the best experts on this subject based on the ideXlab platform.

  • Identification of patient variables that are associated with ventricular End-Diastolic Pressure before the bidirectional Glenn operation.
    Cardiology in the young, 2021
    Co-Authors: Matthew C. Schwartz, Aravinth Karunanandaa, William E. Anderson, J. Rene Herlong, Joseph Paolillo, Gonzalo A. Wallis, Paul M. Kirshbom, Thomas S. Maxey
    Abstract:

    INTRODUCTION Systemic ventricular End-Diastolic Pressure is important in patients with single ventricle heart disease. Predictors of an elevated systemic ventricular End-Diastolic Pressure prior to bidirectional Glenn operation have been incompletely identified. METHODS All patients who underwent bidirectional Glenn operation operation at our centre between January 2007 and March 2017 were retrospectively identified and patient variables were extracted. For patients who had undergone Fontan operation at the time of this study, post-Fontan patient variables were also extracted. RESULTS One-hundred patients were included with a median age at pre-bidirectional Glenn operation catheterisation of 4.5 months. In total, 71 (71%) patients had a systemic right ventricle. At the pre-bidirectional Glenn operation catheterisation, the mean systemic ventricular End-Diastolic Pressure was higher amongst those with systemic right ventricle compared to left ventricle (9.1 mmHg ± 2.1 versus 7.7 ± 2.7 mmHg, p < 0.01). On univariate analysis, pre-bidirectional Glenn operation systemic ventricular End-Diastolic Pressure was positively associated with the presence of a systemic right ventricle (p < 0.01), history of recoarctation (p = 0.03), history of Norwood operation (p = 0.04), and ventricular systolic Pressure (p < 0.01). On multivariate analysis, systemic ventricular End-Diastolic Pressure was positively associated with the presence of a systemic right ventricle (p < 0.01) and ventricular systolic Pressure (p < 0.01). Amongst those who had undergone Fontan operation at the time of study (n = 49), those with a higher pre-bidirectional Glenn operation systemic ventricular End-Diastolic Pressure were more likely to have experienced death, transplantation, or listed for transplantation (p = 0.02) and more likely to have had heart failure symptoms (p = 0.04) at a mean time from Fontan of 5.2 years ± 1.3. CONCLUSIONS In patients undergoing bidirectional Glenn operation operation, the volume-loaded, pre-bidirectional Glenn operation state may expose Diastolic dysfunction that has prognostic value.

  • relation of left ventricular End Diastolic Pressure to right ventricular End Diastolic volume after operative treatment of tetralogy of fallot
    American Journal of Cardiology, 2012
    Co-Authors: Matthew C. Schwartz, Jonathan J. Rome, Matthew J. Gillespie, Kevin K. Whitehead, Matthew A. Harris, Mark A. Fogel, Andrew C. Glatz
    Abstract:

    Left ventricular (LV) Diastolic dysfunction is associated with poor outcomes after tetralogy of Fallot (TOF) repair, although its cause is not known, and its relation to right ventricular (RV) performance has never been examined. The aim of this study was to test the hypothesis that RV dilation leads to LV Diastolic dysfunction after TOF repair. Patients with repaired TOF who underwent cardiac catheterization and cardiac magnetic resonance imaging within 6 months from January 2003 and April 2011 were reviewed to assess the relation of LV End-Diastolic Pressure (LVEDP) and indexed RV End-Diastolic volume (RVEDVi). Thirty-eight patients were included at a median age of 10.1 years (range 0.6 to 54.7). There was a significant linear association between RVEDVi and LVEDP (p = 0.05). RV End-Diastolic Pressure (p <0.001), right pulmonary artery systolic Pressure (p = 0.009), left pulmonary artery systolic Pressure (p = 0.02), and total cardiopulmonary support time (p = 0.04) during TOF repair were also significantly associated with LVEDP. Compared to patients with LVEDP <12 mm Hg, those with LVEDP ≥12 mm Hg had significantly higher mean RVEDVi (135.2 ± 47.8 vs 98.6 ± 28 ml/m(2), p = 0.007) and mean RV End-Diastolic Pressure (11.7 ± 1.6 vs 8.5 ± 2.8 mm Hg, p = 0.0003). In conclusion, after TOF repair, LVEDP is significantly associated with RVEDVi. Furthermore, mean RVEDVi is significantly higher in patients with LVEDP ≥12 mm Hg. These findings support the theory that RV dilation may impair LV Diastolic function and that LV parameters may also be important to consider in determining timing of pulmonary valve replacement.

  • Relation of left ventricular End Diastolic Pressure to right ventricular End Diastolic volume after operative treatment of tetralogy of fallot.
    The American journal of cardiology, 2011
    Co-Authors: Matthew C. Schwartz, Jonathan J. Rome, Matthew J. Gillespie, Kevin K. Whitehead, Matthew A. Harris, Mark A. Fogel, Andrew C. Glatz
    Abstract:

    Left ventricular (LV) Diastolic dysfunction is associated with poor outcomes after tetralogy of Fallot (TOF) repair, although its cause is not known, and its relation to right ventricular (RV) performance has never been examined. The aim of this study was to test the hypothesis that RV dilation leads to LV Diastolic dysfunction after TOF repair. Patients with repaired TOF who underwent cardiac catheterization and cardiac magnetic resonance imaging within 6 months from January 2003 and April 2011 were reviewed to assess the relation of LV End-Diastolic Pressure (LVEDP) and indexed RV End-Diastolic volume (RVEDVi). Thirty-eight patients were included at a median age of 10.1 years (range 0.6 to 54.7). There was a significant linear association between RVEDVi and LVEDP (p = 0.05). RV End-Diastolic Pressure (p

  • Abstract 12799: Left Ventricular End-Diastolic Pressure Correlates with Right Ventricular End-Diastolic Volume in Patients Following Tetralogy of Fallot Repair
    Circulation, 2010
    Co-Authors: Matthew C. Schwartz, Jonathan J. Rome, Matthew A. Harris, Mark C Fogel, Andrew C. Glatz
    Abstract:

    Introduction: Right ventricular dilation is a long-term complication after tetralogy of Fallot (TOF) repair and is associated with poor outcomes. Left ventricular End-Diastolic Pressure (LVEDP) ≥12...