The Experts below are selected from a list of 24 Experts worldwide ranked by ideXlab platform

Takashi Akamizu - One of the best experts on this subject based on the ideXlab platform.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report
    Diabetes Therapy, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Introduction Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. Case Report The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. Conclusion An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report.
    Diabetes therapy : research treatment and education of diabetes and related disorders, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.

Ken Takeshima - One of the best experts on this subject based on the ideXlab platform.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report
    Diabetes Therapy, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Introduction Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. Case Report The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. Conclusion An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report.
    Diabetes therapy : research treatment and education of diabetes and related disorders, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.

Machi Furuta - One of the best experts on this subject based on the ideXlab platform.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report
    Diabetes Therapy, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Introduction Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. Case Report The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. Conclusion An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report.
    Diabetes therapy : research treatment and education of diabetes and related disorders, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.

Hiroyuki Ariyasu - One of the best experts on this subject based on the ideXlab platform.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report
    Diabetes Therapy, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Introduction Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. Case Report The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. Conclusion An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report.
    Diabetes therapy : research treatment and education of diabetes and related disorders, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.

Hiroshi Iwakura - One of the best experts on this subject based on the ideXlab platform.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report
    Diabetes Therapy, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Introduction Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. Case Report The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. Conclusion An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.

  • Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report.
    Diabetes therapy : research treatment and education of diabetes and related disorders, 2018
    Co-Authors: Ken Takeshima, Hiroyuki Ariyasu, Hiroshi Iwakura, Shintaro Kawai, Shinsuke Uraki, Hidefumi Inaba, Machi Furuta, Kenji Warigaya, Shin-ichi Murata, Takashi Akamizu
    Abstract:

    Autoimmune pancreatitis (AIP) is a subset of inflammatory pancreatic disease, responsive to corticosteroid therapy. It is prone to being affected by diabetes mellitus, but the effectiveness of steroid therapy on pancreatic Endocrine Function is still controversial. We present a case of AIP, focusing on pancreatic Endocrine Function after steroid therapy. The patient was referred to our hospital with exacerbation of diabetic control and pancreatic swelling. By admission, the insulin secretory capacity was severely impaired. The patient was diagnosed with AIP and treated with prednisolone, resulting in marked improvement of the pancreatic swelling. Glycemic control worsened transiently after initiation of steroid therapy, but insulin requirements decreased along with tapering prednisolone dosage. Pancreatic cytology showed that the acinar structure had been destroyed, and the islets had disappeared. Insulin and glucagon immunostaining revealed slightly scattered alpha and beta cells within the fibrotic stroma. The patient notably showed improved pancreatic alpha cell Function predominantly after steroid therapy, despite partial improvement of beta cell Function. An imbalance between alpha and beta cell Function may contribute to insufficient diabetic control in some patients with AIP. The pancreatic Endocrine Function Test in combination with pancreatic cytology could be helpful when considering the treatment strategy for diabetic control in patients with AIP.