The Experts below are selected from a list of 21 Experts worldwide ranked by ideXlab platform
Aiym Kaiyrlykyzy - One of the best experts on this subject based on the ideXlab platform.
-
Endometrial histology in severely obese bariatric surgery candidates: an exploratory analysis
2015Co-Authors: Aiym Kaiyrlykyzy, Kaiyrlykyzy Aiym, Freese, Kyle E., Elishaev Esther, Bovbjerg, Dana H., Ramanathan Ramesh, Hamad, Giselle G., Mccloskey Carol, Althouse, Andrew D., Huang MarilynAbstract:Abstract BackgroundEndometrial pathology risk has been linked to obesity; however, little is known of its prevalence in severely obese women not seeking care for Endometrial pathology associated symptoms. This pilot study was designed to explore the frequency and risk factors associated with Endometrial pathology in cancer-free, severely obese, bariatric surgery candidates using the Pipelle Endometrial sampling technique (SureFlex Preferred Curette, Bioteque America, Inc, New Taipei City, Taiwan). MethodsTwenty-nine severely obese bariatric surgery candidates with intact uteruses and no history of Endometrial cancer or Endometrial ablation were included in this subanalysis from a larger cohort of 47. Endometrial samples were obtained using a Pipelle Endometrial Suction Curette at a single time point before surgery. Logistic regression was used to assess the relationship between body mass index and Endometrial pathology when adjusting for age and race. ResultsOf the 29 successful biopsies, 8 (27.6%) were classified as abnormal endometrium: 1 was classified as complex atypical hyperplasia, 1 was classified as hyperplasia without atypia, 4 samples were identified with Endometrial polyps, and 2 samples were identified with metaplasia. None presented with cancer. Increasing body mass index was significantly associated with higher risk of abnormal endometrium (OR = 1.19, 95% CI [1.03–1.36], P = .01). ConclusionsThe findings in this sample suggest that obesity may be associated with increased risk of having undiagnosed Endometrial pathology. More thorough examination of relationships between levels of obesity and Endometrial pathology are needed to better characterize high cancer risk groups who may benefit from introducing new screening measures
-
integrated health original article Endometrial histology in severely obese bariatric surgery candidates an exploratory analysis
2015Co-Authors: Aiym Kaiyrlykyzy, Kyle E Freese, Esther Elishaev, Dana H Bovbjerg, Ramesh C Ramanathan, Giselle G Hamad, Carol A Mccloskey, Andrew D Althouse, Marilyn Huang, Robert P EdwardsAbstract:Background: Endometrial pathology risk has been linked to obesity; however, little is known of its prevalence in severely obese women not seeking care for Endometrial pathology associated symptoms. This pilot study was designed to explore the frequency and risk factors associated with Endometrial pathology in cancer-free, severely obese, bariatric surgery candidates using the Pipelle Endometrial sampling technique (SureFlex Preferred Curette, Bioteque America, Inc, New Taipei City, Taiwan). Methods: Twenty-nine severely obese bariatric surgery candidates with intact uteruses and no history of Endometrial cancer or Endometrial ablation were included in this subanalysis from a larger cohort of 47. Endometrial samples were obtained using a Pipelle Endometrial Suction Curette at a single time point before surgery. Logistic regression was used to assess the relationship between body mass index and Endometrial pathology when adjusting for age and race. Results: Of the 29 successful biopsies, 8 (27.6%) were classified as abnormal endometrium: 1 was classified as complex atypical hyperplasia, 1 was classified as hyperplasia without atypia, 4 samples were identified with Endometrial polyps, and 2 samples were identified with metaplasia. None presented with cancer. Increasing body mass index was significantly associated with higher risk of abnormal endometrium (OR ¼ 1.19, 95% CI [1.03–1.36], P ¼ .01). Conclusions: The findings in this sample suggest that obesity may be associated with increased risk of having undiagnosed Endometrial pathology. More thorough examination of relationships between levels of obesity and Endometrial pathology are needed to better characterize high cancer risk groups who may benefit from introducing new screening measures. (Surg Obes Relat Dis 2015;11:653– 658.) r 2015 American Society for Metabolic and Bariatric Surgery. All rights reserved.
Robert P Edwards - One of the best experts on this subject based on the ideXlab platform.
-
integrated health original article Endometrial histology in severely obese bariatric surgery candidates an exploratory analysis
2015Co-Authors: Aiym Kaiyrlykyzy, Kyle E Freese, Esther Elishaev, Dana H Bovbjerg, Ramesh C Ramanathan, Giselle G Hamad, Carol A Mccloskey, Andrew D Althouse, Marilyn Huang, Robert P EdwardsAbstract:Background: Endometrial pathology risk has been linked to obesity; however, little is known of its prevalence in severely obese women not seeking care for Endometrial pathology associated symptoms. This pilot study was designed to explore the frequency and risk factors associated with Endometrial pathology in cancer-free, severely obese, bariatric surgery candidates using the Pipelle Endometrial sampling technique (SureFlex Preferred Curette, Bioteque America, Inc, New Taipei City, Taiwan). Methods: Twenty-nine severely obese bariatric surgery candidates with intact uteruses and no history of Endometrial cancer or Endometrial ablation were included in this subanalysis from a larger cohort of 47. Endometrial samples were obtained using a Pipelle Endometrial Suction Curette at a single time point before surgery. Logistic regression was used to assess the relationship between body mass index and Endometrial pathology when adjusting for age and race. Results: Of the 29 successful biopsies, 8 (27.6%) were classified as abnormal endometrium: 1 was classified as complex atypical hyperplasia, 1 was classified as hyperplasia without atypia, 4 samples were identified with Endometrial polyps, and 2 samples were identified with metaplasia. None presented with cancer. Increasing body mass index was significantly associated with higher risk of abnormal endometrium (OR ¼ 1.19, 95% CI [1.03–1.36], P ¼ .01). Conclusions: The findings in this sample suggest that obesity may be associated with increased risk of having undiagnosed Endometrial pathology. More thorough examination of relationships between levels of obesity and Endometrial pathology are needed to better characterize high cancer risk groups who may benefit from introducing new screening measures. (Surg Obes Relat Dis 2015;11:653– 658.) r 2015 American Society for Metabolic and Bariatric Surgery. All rights reserved.
Huang Marilyn - One of the best experts on this subject based on the ideXlab platform.
-
Endometrial histology in severely obese bariatric surgery candidates: an exploratory analysis
2015Co-Authors: Aiym Kaiyrlykyzy, Kaiyrlykyzy Aiym, Freese, Kyle E., Elishaev Esther, Bovbjerg, Dana H., Ramanathan Ramesh, Hamad, Giselle G., Mccloskey Carol, Althouse, Andrew D., Huang MarilynAbstract:Abstract BackgroundEndometrial pathology risk has been linked to obesity; however, little is known of its prevalence in severely obese women not seeking care for Endometrial pathology associated symptoms. This pilot study was designed to explore the frequency and risk factors associated with Endometrial pathology in cancer-free, severely obese, bariatric surgery candidates using the Pipelle Endometrial sampling technique (SureFlex Preferred Curette, Bioteque America, Inc, New Taipei City, Taiwan). MethodsTwenty-nine severely obese bariatric surgery candidates with intact uteruses and no history of Endometrial cancer or Endometrial ablation were included in this subanalysis from a larger cohort of 47. Endometrial samples were obtained using a Pipelle Endometrial Suction Curette at a single time point before surgery. Logistic regression was used to assess the relationship between body mass index and Endometrial pathology when adjusting for age and race. ResultsOf the 29 successful biopsies, 8 (27.6%) were classified as abnormal endometrium: 1 was classified as complex atypical hyperplasia, 1 was classified as hyperplasia without atypia, 4 samples were identified with Endometrial polyps, and 2 samples were identified with metaplasia. None presented with cancer. Increasing body mass index was significantly associated with higher risk of abnormal endometrium (OR = 1.19, 95% CI [1.03–1.36], P = .01). ConclusionsThe findings in this sample suggest that obesity may be associated with increased risk of having undiagnosed Endometrial pathology. More thorough examination of relationships between levels of obesity and Endometrial pathology are needed to better characterize high cancer risk groups who may benefit from introducing new screening measures
J Gonzalez - One of the best experts on this subject based on the ideXlab platform.
-
vabra aspirator and pipelle Endometrial Suction Curette a comparison
Journal of Reproductive Medicine, 1998Co-Authors: P D Manganiello, L J Burrows, B J Dain, J GonzalezAbstract:Objective To compare the Pipelle Suction Curette with the Vabra aspirating catheter in terms of their ability to obtain a sufficient amount of tissue (> or = 1 mm2 of endometrium) in order to make a histologic diagnosis. Study design A prospective, randomized, double-blind, crossover study at Dartmouth-Hitchcock Medical Center, which serves as the clinical staff of the Dartmouth Medical School. Results Agreement between the Pipelle and Vabra was high: 74 of 79 (93.7%) samples. The Pipelle obtained adequate samples in 78 of 79 (98.7%) cases as compared with 75 of 79 (94.9%) for the Vabra. The McNemar test comparing these two proportions, adjusting for the fact that the Pipelle and Vabra readings were taken on the same subjects at the same visits, yielded a nonsignificant result (P = .180). Conclusion The Pipelle and Vabra have equal diagnostic accuracy.
Marilyn Huang - One of the best experts on this subject based on the ideXlab platform.
-
integrated health original article Endometrial histology in severely obese bariatric surgery candidates an exploratory analysis
2015Co-Authors: Aiym Kaiyrlykyzy, Kyle E Freese, Esther Elishaev, Dana H Bovbjerg, Ramesh C Ramanathan, Giselle G Hamad, Carol A Mccloskey, Andrew D Althouse, Marilyn Huang, Robert P EdwardsAbstract:Background: Endometrial pathology risk has been linked to obesity; however, little is known of its prevalence in severely obese women not seeking care for Endometrial pathology associated symptoms. This pilot study was designed to explore the frequency and risk factors associated with Endometrial pathology in cancer-free, severely obese, bariatric surgery candidates using the Pipelle Endometrial sampling technique (SureFlex Preferred Curette, Bioteque America, Inc, New Taipei City, Taiwan). Methods: Twenty-nine severely obese bariatric surgery candidates with intact uteruses and no history of Endometrial cancer or Endometrial ablation were included in this subanalysis from a larger cohort of 47. Endometrial samples were obtained using a Pipelle Endometrial Suction Curette at a single time point before surgery. Logistic regression was used to assess the relationship between body mass index and Endometrial pathology when adjusting for age and race. Results: Of the 29 successful biopsies, 8 (27.6%) were classified as abnormal endometrium: 1 was classified as complex atypical hyperplasia, 1 was classified as hyperplasia without atypia, 4 samples were identified with Endometrial polyps, and 2 samples were identified with metaplasia. None presented with cancer. Increasing body mass index was significantly associated with higher risk of abnormal endometrium (OR ¼ 1.19, 95% CI [1.03–1.36], P ¼ .01). Conclusions: The findings in this sample suggest that obesity may be associated with increased risk of having undiagnosed Endometrial pathology. More thorough examination of relationships between levels of obesity and Endometrial pathology are needed to better characterize high cancer risk groups who may benefit from introducing new screening measures. (Surg Obes Relat Dis 2015;11:653– 658.) r 2015 American Society for Metabolic and Bariatric Surgery. All rights reserved.