The Experts below are selected from a list of 33 Experts worldwide ranked by ideXlab platform
Taichu Lau - One of the best experts on this subject based on the ideXlab platform.
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formation of molecular radical cations of Enkephalin Derivatives via collision induced dissociation of electrospray generated copper ii complex ions of amines and peptides
Journal of the American Society for Mass Spectrometry, 2001Co-Authors: Ivan K Chu, Christopher F Rodriguez, Alan C Hopkinson, K Michael W Siu, Taichu LauAbstract:Fragmentation of some electrospray-generated complex ions, [63CuII(amine)M].2+, where M is an Enkephalin Derivative, produces the radical cation of the peptide, M.+. This ion has only been observed when M contains a tyrosyl or tryptophanyl residue plus a basic residue, typically arginyl or lysyl. A typical viable amine is diethylenetriamine. Collision-induced dissociation (CID) of the M.+ ion yields a prominent [M − 106].+ product ion for tyrosine-containing peptides, and a prominent [M − 129].+ ion for a tryptophan-containing peptide. These fragment ions are formed as a result of elimination of the tyrosyl and tryptophanyl side chains. Dissociation of these ions, in turn, produces second generation product ions, many of which are typically absent in the fragmentation of protonated peptide ions. Structures for some of these unusual ions are proposed.
Ivan K Chu - One of the best experts on this subject based on the ideXlab platform.
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formation of molecular radical cations of Enkephalin Derivatives via collision induced dissociation of electrospray generated copper ii complex ions of amines and peptides
Journal of the American Society for Mass Spectrometry, 2001Co-Authors: Ivan K Chu, Christopher F Rodriguez, Alan C Hopkinson, K Michael W Siu, Taichu LauAbstract:Fragmentation of some electrospray-generated complex ions, [63CuII(amine)M].2+, where M is an Enkephalin Derivative, produces the radical cation of the peptide, M.+. This ion has only been observed when M contains a tyrosyl or tryptophanyl residue plus a basic residue, typically arginyl or lysyl. A typical viable amine is diethylenetriamine. Collision-induced dissociation (CID) of the M.+ ion yields a prominent [M − 106].+ product ion for tyrosine-containing peptides, and a prominent [M − 129].+ ion for a tryptophan-containing peptide. These fragment ions are formed as a result of elimination of the tyrosyl and tryptophanyl side chains. Dissociation of these ions, in turn, produces second generation product ions, many of which are typically absent in the fragmentation of protonated peptide ions. Structures for some of these unusual ions are proposed.
Alan C Hopkinson - One of the best experts on this subject based on the ideXlab platform.
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formation of molecular radical cations of Enkephalin Derivatives via collision induced dissociation of electrospray generated copper ii complex ions of amines and peptides
Journal of the American Society for Mass Spectrometry, 2001Co-Authors: Ivan K Chu, Christopher F Rodriguez, Alan C Hopkinson, K Michael W Siu, Taichu LauAbstract:Fragmentation of some electrospray-generated complex ions, [63CuII(amine)M].2+, where M is an Enkephalin Derivative, produces the radical cation of the peptide, M.+. This ion has only been observed when M contains a tyrosyl or tryptophanyl residue plus a basic residue, typically arginyl or lysyl. A typical viable amine is diethylenetriamine. Collision-induced dissociation (CID) of the M.+ ion yields a prominent [M − 106].+ product ion for tyrosine-containing peptides, and a prominent [M − 129].+ ion for a tryptophan-containing peptide. These fragment ions are formed as a result of elimination of the tyrosyl and tryptophanyl side chains. Dissociation of these ions, in turn, produces second generation product ions, many of which are typically absent in the fragmentation of protonated peptide ions. Structures for some of these unusual ions are proposed.
Christopher F Rodriguez - One of the best experts on this subject based on the ideXlab platform.
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formation of molecular radical cations of Enkephalin Derivatives via collision induced dissociation of electrospray generated copper ii complex ions of amines and peptides
Journal of the American Society for Mass Spectrometry, 2001Co-Authors: Ivan K Chu, Christopher F Rodriguez, Alan C Hopkinson, K Michael W Siu, Taichu LauAbstract:Fragmentation of some electrospray-generated complex ions, [63CuII(amine)M].2+, where M is an Enkephalin Derivative, produces the radical cation of the peptide, M.+. This ion has only been observed when M contains a tyrosyl or tryptophanyl residue plus a basic residue, typically arginyl or lysyl. A typical viable amine is diethylenetriamine. Collision-induced dissociation (CID) of the M.+ ion yields a prominent [M − 106].+ product ion for tyrosine-containing peptides, and a prominent [M − 129].+ ion for a tryptophan-containing peptide. These fragment ions are formed as a result of elimination of the tyrosyl and tryptophanyl side chains. Dissociation of these ions, in turn, produces second generation product ions, many of which are typically absent in the fragmentation of protonated peptide ions. Structures for some of these unusual ions are proposed.
K Michael W Siu - One of the best experts on this subject based on the ideXlab platform.
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formation of molecular radical cations of Enkephalin Derivatives via collision induced dissociation of electrospray generated copper ii complex ions of amines and peptides
Journal of the American Society for Mass Spectrometry, 2001Co-Authors: Ivan K Chu, Christopher F Rodriguez, Alan C Hopkinson, K Michael W Siu, Taichu LauAbstract:Fragmentation of some electrospray-generated complex ions, [63CuII(amine)M].2+, where M is an Enkephalin Derivative, produces the radical cation of the peptide, M.+. This ion has only been observed when M contains a tyrosyl or tryptophanyl residue plus a basic residue, typically arginyl or lysyl. A typical viable amine is diethylenetriamine. Collision-induced dissociation (CID) of the M.+ ion yields a prominent [M − 106].+ product ion for tyrosine-containing peptides, and a prominent [M − 129].+ ion for a tryptophan-containing peptide. These fragment ions are formed as a result of elimination of the tyrosyl and tryptophanyl side chains. Dissociation of these ions, in turn, produces second generation product ions, many of which are typically absent in the fragmentation of protonated peptide ions. Structures for some of these unusual ions are proposed.