The Experts below are selected from a list of 165 Experts worldwide ranked by ideXlab platform

Evelyne Sernagor - One of the best experts on this subject based on the ideXlab platform.

  • Pan-retinal characterisation of Light Responses from Ganglion Cells in the Developing Mouse Retina
    Scientific Reports, 2017
    Co-Authors: Gerrit Hilgen, Sahar Pirmoradian, Daniela Pamplona, Pierre Kornprobst, Bruno Cessac, Matthias Hennig, Evelyne Sernagor
    Abstract:

    We have investigated the ontogeny of light-driven responses in mouse retinal ganglion cells (RGCs). Using a large-scale, high-density multielectrode array, we recorded from hundreds to thousands of RGCs simultaneously at pan-retinal level, including dorsal and ventral locations. Responses to di erent contrasts not only revealed a complex developmental pro le for ON, OFF and ON-OFF responses, but also unveiled di erences between dorsal and ventral RGC responses. At eye-opening, dorsal RGCs of all types were more responsive to light, perhaps indicating an Environmental Priority to nest viewing for pre-weaning pups. The developmental pro le of ON and OFF responses exhibited antagonistic behaviour, with the strongest ON responses shortly after eye-opening, followed by an increase in the strength of OFF responses later on. Further, we found that with maturation receptive eld (RF) center sizes decrease, spike-triggered averaged responses to white noise become stronger, and centers become more circular while maintaining di erences between RGC types. We conclude that the maturation of retinal functionality is not spatially homogeneous, likely re ecting ecological requirements that favour earlier maturation of the dorsal retina.

  • Pan-retinal characterisation of Light Responses from Ganglion Cells in the Developing Mouse Retina
    2016
    Co-Authors: Gerrit Hilgen, Sahar Pirmoradian, Daniela Pamplona, Pierre Kornprobst, Bruno Cessac, Matthias Hennig, Evelyne Sernagor
    Abstract:

    We have investigated the ontogeny of light-driven responses in mouse retinal ganglion cells (RGCs). Using a large-scale, high-density multielectrode array, we recorded from hundreds to thousands of RGCs simultaneously at pan-retinal level, including dorsal and ventral locations. Responses to different contrasts not only revealed a complex developmental profile for ON, OFF and ON-OFF RGC types, but also unveiled differences between dorsal and ventral RGCs. At eye-opening, dorsal RGCs of all types were more responsive to light, perhaps indicating an Environmental Priority to nest viewing for pre-weaning pups. The developmental profile of ON and OFF RGCs exhibited antagonistic behavior, with the strongest ON responses shortly after eye-opening, followed by an increase in the strength of OFF responses later on. Further, we found that with maturation receptive field (RF) center sizes decrease, responses to light get stronger, and centers become more circular while seeing differences in all of them between RGC types. These findings show that retinal functionality is not spatially homogeneous, likely reflecting ecological requirements that favour the early development of dorsal retina, and reflecting different roles in vision in the mature animal.

Sophie Fourmentin - One of the best experts on this subject based on the ideXlab platform.

  • Remediation technologies using cyclodextrins: an overview
    Environmental Chemistry Letters, 2012
    Co-Authors: David Landy, Anne Ponchel, Isabelle Mallard, Eric Monflier, Sophie Fourmentin
    Abstract:

    Nowadays, the human activity and the modern way of life are responsible for the increase of the Environmental pollution. Industrial processes generate a variety of molecules that may pollute air, water, and soils due to negative impacts for ecosystems and humans. The development of innovative remediation technologies has thus emerged as a significant Environmental Priority. Within this scope, supramolecular chemistry, which is a recent discipline, could provide solutions. In particular, cyclodextrins (CDs) are a family of cyclic oligosaccharides having a low-polarity cavity in which organic compounds of appropriate shape and size can form inclusion complexes. This unique property makes them suitable for application in Environmental protection. Here, we review the use of cyclodextrins and cyclodextrin derivatives in remediation technologies. Accordingly, the present review shows the advantages of using CDs in soil, groundwater, wastewater, and atmosphere remediation. Resulting processes are highly versatile, since the complexing ability of CD is applicable to a wide range of pollutants. They may also been referred to green processes, according to the CD innocuity. Moreover, as inclusion phenomena correspond to reversible equilibriums, a major trend in the CD Environmental application field is to develop methods, which combine supramolecular chemistry and irreversible processes, as advanced oxidation or biodegradation. Such processes might lead to a complete remediation of pollutants and eventually to the CD recycling.

  • Cyclodextrins for Remediation Technologies
    Environmental Chemistry for a Sustainable World, 2012
    Co-Authors: David Landy, Anne Ponchel, Isabelle Mallard, Eric Monflier, Sophie Fourmentin
    Abstract:

    Human activity and the modern way of life are responsible for the increase of Environmental pollution. Industrial processes generate many substances that pollute air, water and soils with negative impacts for ecosystems and humans. The development of innovative remediation technologies has thus emerged as a significant Environmental Priority. Supramolecular chemistry can provide promising remediation methods to solve pollution issues. In particular, cyclodextrins (CDs) are a family of cyclic oligosaccharides that are composed of α-1,4-linked glucopyranose subunits. Cyclodextrins have thus a low-polarity cavity in which organic pollutants of appropriate shape and size can form inclusion complexes. This unique property makes cyclodextrins suitable for application in Environmental protection by pollutant trapping. Accordingly, the present review lists the advantages of using cyclodextrins in soil, groundwater, wastewater and atmosphere remediation. The inclusion mechanism have been used in soil, water and air, either as solubilizing agent when the cyclodextrin is diluted in aqueous solution, or as trapping agent when cyclodextrin is immobilized on various supports. Resulting processes are highly versatile, since the complexing ability of cyclodextrins includes a wide range of pollutants. Remediation using cyclodextrins is a green processe due to cyclodextrins innocuity. Moreover, since inclusion involves reversible equilibriums, a major trend in the cyclodextrin Environmental application field is to develop methods that combine both supramolecular chemistry and irreversible processes such as advanced oxidation or biodegradation. Such processes could lead to a complete remediation of pollutants and to cyclodextrin recycling.

Gerrit Hilgen - One of the best experts on this subject based on the ideXlab platform.

  • Pan-retinal characterisation of Light Responses from Ganglion Cells in the Developing Mouse Retina
    Scientific Reports, 2017
    Co-Authors: Gerrit Hilgen, Sahar Pirmoradian, Daniela Pamplona, Pierre Kornprobst, Bruno Cessac, Matthias Hennig, Evelyne Sernagor
    Abstract:

    We have investigated the ontogeny of light-driven responses in mouse retinal ganglion cells (RGCs). Using a large-scale, high-density multielectrode array, we recorded from hundreds to thousands of RGCs simultaneously at pan-retinal level, including dorsal and ventral locations. Responses to di erent contrasts not only revealed a complex developmental pro le for ON, OFF and ON-OFF responses, but also unveiled di erences between dorsal and ventral RGC responses. At eye-opening, dorsal RGCs of all types were more responsive to light, perhaps indicating an Environmental Priority to nest viewing for pre-weaning pups. The developmental pro le of ON and OFF responses exhibited antagonistic behaviour, with the strongest ON responses shortly after eye-opening, followed by an increase in the strength of OFF responses later on. Further, we found that with maturation receptive eld (RF) center sizes decrease, spike-triggered averaged responses to white noise become stronger, and centers become more circular while maintaining di erences between RGC types. We conclude that the maturation of retinal functionality is not spatially homogeneous, likely re ecting ecological requirements that favour earlier maturation of the dorsal retina.

  • Pan-retinal characterisation of Light Responses from Ganglion Cells in the Developing Mouse Retina
    2016
    Co-Authors: Gerrit Hilgen, Sahar Pirmoradian, Daniela Pamplona, Pierre Kornprobst, Bruno Cessac, Matthias Hennig, Evelyne Sernagor
    Abstract:

    We have investigated the ontogeny of light-driven responses in mouse retinal ganglion cells (RGCs). Using a large-scale, high-density multielectrode array, we recorded from hundreds to thousands of RGCs simultaneously at pan-retinal level, including dorsal and ventral locations. Responses to different contrasts not only revealed a complex developmental profile for ON, OFF and ON-OFF RGC types, but also unveiled differences between dorsal and ventral RGCs. At eye-opening, dorsal RGCs of all types were more responsive to light, perhaps indicating an Environmental Priority to nest viewing for pre-weaning pups. The developmental profile of ON and OFF RGCs exhibited antagonistic behavior, with the strongest ON responses shortly after eye-opening, followed by an increase in the strength of OFF responses later on. Further, we found that with maturation receptive field (RF) center sizes decrease, responses to light get stronger, and centers become more circular while seeing differences in all of them between RGC types. These findings show that retinal functionality is not spatially homogeneous, likely reflecting ecological requirements that favour the early development of dorsal retina, and reflecting different roles in vision in the mature animal.

David Landy - One of the best experts on this subject based on the ideXlab platform.

  • Remediation technologies using cyclodextrins: an overview
    Environmental Chemistry Letters, 2012
    Co-Authors: David Landy, Anne Ponchel, Isabelle Mallard, Eric Monflier, Sophie Fourmentin
    Abstract:

    Nowadays, the human activity and the modern way of life are responsible for the increase of the Environmental pollution. Industrial processes generate a variety of molecules that may pollute air, water, and soils due to negative impacts for ecosystems and humans. The development of innovative remediation technologies has thus emerged as a significant Environmental Priority. Within this scope, supramolecular chemistry, which is a recent discipline, could provide solutions. In particular, cyclodextrins (CDs) are a family of cyclic oligosaccharides having a low-polarity cavity in which organic compounds of appropriate shape and size can form inclusion complexes. This unique property makes them suitable for application in Environmental protection. Here, we review the use of cyclodextrins and cyclodextrin derivatives in remediation technologies. Accordingly, the present review shows the advantages of using CDs in soil, groundwater, wastewater, and atmosphere remediation. Resulting processes are highly versatile, since the complexing ability of CD is applicable to a wide range of pollutants. They may also been referred to green processes, according to the CD innocuity. Moreover, as inclusion phenomena correspond to reversible equilibriums, a major trend in the CD Environmental application field is to develop methods, which combine supramolecular chemistry and irreversible processes, as advanced oxidation or biodegradation. Such processes might lead to a complete remediation of pollutants and eventually to the CD recycling.

  • Cyclodextrins for Remediation Technologies
    Environmental Chemistry for a Sustainable World, 2012
    Co-Authors: David Landy, Anne Ponchel, Isabelle Mallard, Eric Monflier, Sophie Fourmentin
    Abstract:

    Human activity and the modern way of life are responsible for the increase of Environmental pollution. Industrial processes generate many substances that pollute air, water and soils with negative impacts for ecosystems and humans. The development of innovative remediation technologies has thus emerged as a significant Environmental Priority. Supramolecular chemistry can provide promising remediation methods to solve pollution issues. In particular, cyclodextrins (CDs) are a family of cyclic oligosaccharides that are composed of α-1,4-linked glucopyranose subunits. Cyclodextrins have thus a low-polarity cavity in which organic pollutants of appropriate shape and size can form inclusion complexes. This unique property makes cyclodextrins suitable for application in Environmental protection by pollutant trapping. Accordingly, the present review lists the advantages of using cyclodextrins in soil, groundwater, wastewater and atmosphere remediation. The inclusion mechanism have been used in soil, water and air, either as solubilizing agent when the cyclodextrin is diluted in aqueous solution, or as trapping agent when cyclodextrin is immobilized on various supports. Resulting processes are highly versatile, since the complexing ability of cyclodextrins includes a wide range of pollutants. Remediation using cyclodextrins is a green processe due to cyclodextrins innocuity. Moreover, since inclusion involves reversible equilibriums, a major trend in the cyclodextrin Environmental application field is to develop methods that combine both supramolecular chemistry and irreversible processes such as advanced oxidation or biodegradation. Such processes could lead to a complete remediation of pollutants and to cyclodextrin recycling.

G. T. Mcdonald - One of the best experts on this subject based on the ideXlab platform.

  • The assets, threats and solvability (ATS) model for setting Environmental priorities
    Journal of Environmental Policy & Planning, 2006
    Co-Authors: Stefan Hajkowicz, G. T. Mcdonald
    Abstract:

    Abstract Environmental and natural resource management agencies routinely encounter the task of setting priorities. Limited time, staff and financial resources result in some projects, programmes or issues being given greater attention than others. In multi-stakeholder and multi-objective settings the decision-making process is complex. The task is often made harder by incomplete or inaccurate datasets. Decision makers will aim to adopt a procedure that is analytically robust, auditable, transparent and understandable. This paper presents the assets, threats and solvability (ATS) model for structuring an Environmental Priority-setting problem. A brief illustration of its use for setting priorities in the Wet Tropics of North Queensland is given. The ATS model provides a structured decision procedure applicable with limited information in a multi-objective policy environment. It helps guide the selection and application of Priority-setting criteria under these conditions.