The Experts below are selected from a list of 48 Experts worldwide ranked by ideXlab platform
Xingtao Zhou - One of the best experts on this subject based on the ideXlab platform.
-
using donor lenticules obtained through smile for an Epikeratophakia technique combined with phototherapeutic keratectomy
Journal of Refractive Surgery, 2016Co-Authors: Jing Zhao, Yang Shen, Mi Tian, Xingtao ZhouAbstract:PURPOSE: To investigate the feasibility, safety, and efficacy of using a donor lenticule created during small incision lenticule extraction (SMILE) in an Epikeratophakia technique combined with phototherapeutic keratectomy (PTK). METHODS: Six patients with decreased visual acuity due to a recurrence of corneal dystrophy were included in this prospective pilot study. PTK was performed using the MEL 80 excimer laser (Carl Zeiss Meditec, Jena, Germany) followed by the transplantation of donor lenticules onto the recipient eyes. These lenticules were extracted during SMILE procedures using the VisuMax femtosecond laser (Carl Zeiss Meditec) on 6 donors with myopia and served as the Epikeratophakia tissue. RESULTS: The surgeries and postoperative follow-up examinations were uneventful and no complications were noted over 6 months of follow-up. The epithelium remodelling was achieved within 1 month. At the last measurement, the corrected distance visual acuity of all recipient eyes gained at least two lines. Five eyes (83.3%) gained at least two lines of uncorrected distance visual acuity compared to their preoperative levels. Mean keratometric power increased by 5.97 ± 3.73 diopters and central corneal thickness increased by 55.25 ± 36.38 µm. The epithelium healed and the lenticules remained clear over the follow-up period as observed under slit-lamp examination. Anterior segment optical coherence tomography observation showed the lenticule was transparent with a visible demarcation line during the follow-up examination. CONCLUSIONS: The use of a SMILE lenticule as a donor lenticule for an Epikeratophakia technique appears feasible and safe in the short term. The predictability and long-term effects need further investigation. [J Refract Surg. 2016;32(12):840-845.].
Jing Zhao - One of the best experts on this subject based on the ideXlab platform.
-
using donor lenticules obtained through smile for an Epikeratophakia technique combined with phototherapeutic keratectomy
Journal of Refractive Surgery, 2016Co-Authors: Jing Zhao, Yang Shen, Mi Tian, Xingtao ZhouAbstract:PURPOSE: To investigate the feasibility, safety, and efficacy of using a donor lenticule created during small incision lenticule extraction (SMILE) in an Epikeratophakia technique combined with phototherapeutic keratectomy (PTK). METHODS: Six patients with decreased visual acuity due to a recurrence of corneal dystrophy were included in this prospective pilot study. PTK was performed using the MEL 80 excimer laser (Carl Zeiss Meditec, Jena, Germany) followed by the transplantation of donor lenticules onto the recipient eyes. These lenticules were extracted during SMILE procedures using the VisuMax femtosecond laser (Carl Zeiss Meditec) on 6 donors with myopia and served as the Epikeratophakia tissue. RESULTS: The surgeries and postoperative follow-up examinations were uneventful and no complications were noted over 6 months of follow-up. The epithelium remodelling was achieved within 1 month. At the last measurement, the corrected distance visual acuity of all recipient eyes gained at least two lines. Five eyes (83.3%) gained at least two lines of uncorrected distance visual acuity compared to their preoperative levels. Mean keratometric power increased by 5.97 ± 3.73 diopters and central corneal thickness increased by 55.25 ± 36.38 µm. The epithelium healed and the lenticules remained clear over the follow-up period as observed under slit-lamp examination. Anterior segment optical coherence tomography observation showed the lenticule was transparent with a visible demarcation line during the follow-up examination. CONCLUSIONS: The use of a SMILE lenticule as a donor lenticule for an Epikeratophakia technique appears feasible and safe in the short term. The predictability and long-term effects need further investigation. [J Refract Surg. 2016;32(12):840-845.].
H W Thompson - One of the best experts on this subject based on the ideXlab platform.
-
automated keratoconus screening with corneal topography analysis
Investigative Ophthalmology & Visual Science, 1994Co-Authors: Naoyuki Maeda, Michael K Smolek, H W ThompsonAbstract:Purpose Although visual inspection of corneal topography maps by trained experts can be powerful, this method is inherently subjective. Quantitative classification methods that can detect and classify abnormal topographic patterns would be useful. An automated system was developed to differentiate keratoconus patterns from other conditions using computer-assisted videokeratoscopy. Methods This system combined a classification tree with a linear discriminant function derived from discriminant analysis of eight indices obtained from TMS-1 videokeratoscope data. One hundred corneas with a variety of diagnoses (keratoconus, normal, keratoplasty, Epikeratophakia, excimer laser photorefractive keratectomy, radical keratotomy, contact lens-induced warpage, and others) were used for training, and a validation set of 100 additional corneas was used to evaluate the results. Results In the training set, all 22 cases of clinically diagnosed keratoconus were detected with three-false-positive cases (sensitivity 100%, specificity 96%, and accuracy 97%). With the validation set, 25 out of 28 keratoconus cases were detected with one false-positive case, which was a transplanted cornea (sensitivity 89%, specificity 99%, and accuracy 96%). Conclusions This system can be used as a screening procedure to distinguish clinical keratoconus from other corneal topographies. This quantitative classification method may also aid in refining the clinical interpretation of topographic maps.
Yang Shen - One of the best experts on this subject based on the ideXlab platform.
-
using donor lenticules obtained through smile for an Epikeratophakia technique combined with phototherapeutic keratectomy
Journal of Refractive Surgery, 2016Co-Authors: Jing Zhao, Yang Shen, Mi Tian, Xingtao ZhouAbstract:PURPOSE: To investigate the feasibility, safety, and efficacy of using a donor lenticule created during small incision lenticule extraction (SMILE) in an Epikeratophakia technique combined with phototherapeutic keratectomy (PTK). METHODS: Six patients with decreased visual acuity due to a recurrence of corneal dystrophy were included in this prospective pilot study. PTK was performed using the MEL 80 excimer laser (Carl Zeiss Meditec, Jena, Germany) followed by the transplantation of donor lenticules onto the recipient eyes. These lenticules were extracted during SMILE procedures using the VisuMax femtosecond laser (Carl Zeiss Meditec) on 6 donors with myopia and served as the Epikeratophakia tissue. RESULTS: The surgeries and postoperative follow-up examinations were uneventful and no complications were noted over 6 months of follow-up. The epithelium remodelling was achieved within 1 month. At the last measurement, the corrected distance visual acuity of all recipient eyes gained at least two lines. Five eyes (83.3%) gained at least two lines of uncorrected distance visual acuity compared to their preoperative levels. Mean keratometric power increased by 5.97 ± 3.73 diopters and central corneal thickness increased by 55.25 ± 36.38 µm. The epithelium healed and the lenticules remained clear over the follow-up period as observed under slit-lamp examination. Anterior segment optical coherence tomography observation showed the lenticule was transparent with a visible demarcation line during the follow-up examination. CONCLUSIONS: The use of a SMILE lenticule as a donor lenticule for an Epikeratophakia technique appears feasible and safe in the short term. The predictability and long-term effects need further investigation. [J Refract Surg. 2016;32(12):840-845.].
Mi Tian - One of the best experts on this subject based on the ideXlab platform.
-
using donor lenticules obtained through smile for an Epikeratophakia technique combined with phototherapeutic keratectomy
Journal of Refractive Surgery, 2016Co-Authors: Jing Zhao, Yang Shen, Mi Tian, Xingtao ZhouAbstract:PURPOSE: To investigate the feasibility, safety, and efficacy of using a donor lenticule created during small incision lenticule extraction (SMILE) in an Epikeratophakia technique combined with phototherapeutic keratectomy (PTK). METHODS: Six patients with decreased visual acuity due to a recurrence of corneal dystrophy were included in this prospective pilot study. PTK was performed using the MEL 80 excimer laser (Carl Zeiss Meditec, Jena, Germany) followed by the transplantation of donor lenticules onto the recipient eyes. These lenticules were extracted during SMILE procedures using the VisuMax femtosecond laser (Carl Zeiss Meditec) on 6 donors with myopia and served as the Epikeratophakia tissue. RESULTS: The surgeries and postoperative follow-up examinations were uneventful and no complications were noted over 6 months of follow-up. The epithelium remodelling was achieved within 1 month. At the last measurement, the corrected distance visual acuity of all recipient eyes gained at least two lines. Five eyes (83.3%) gained at least two lines of uncorrected distance visual acuity compared to their preoperative levels. Mean keratometric power increased by 5.97 ± 3.73 diopters and central corneal thickness increased by 55.25 ± 36.38 µm. The epithelium healed and the lenticules remained clear over the follow-up period as observed under slit-lamp examination. Anterior segment optical coherence tomography observation showed the lenticule was transparent with a visible demarcation line during the follow-up examination. CONCLUSIONS: The use of a SMILE lenticule as a donor lenticule for an Epikeratophakia technique appears feasible and safe in the short term. The predictability and long-term effects need further investigation. [J Refract Surg. 2016;32(12):840-845.].