The Experts below are selected from a list of 54 Experts worldwide ranked by ideXlab platform

Hatem S Shehata - One of the best experts on this subject based on the ideXlab platform.

  • Prevalence of primary Headache disorders in Fayoum Governorate, Egypt
    Journal of Headache and Pain, 2015
    Co-Authors: Naglaa A. El-sherbiny, Mohamed Masoud, Nevin M Shalaby, Hatem S Shehata
    Abstract:

    There is abundance of epidemiological studies of Headache in developed and western countries; however, data in developing countries and in Egypt are still lacking. This study aims to detect the prevalence of primary Headache disorders in both urban and rural sectors in Fayoum governorate, Egypt. A total of 2600 subjects were included using multi-stage stratified systematic random sampling, with respondent rate of 91.3 %. A pre-designed Arabic version, interviewer-administered, pilot tested structured questionnaire was developed according to The International Classification of Headache Disorders, 3rd edition (beta version), and this questionnaire was validated and the strength of agreement in Headache diagnosis was good. The 1-year Headache prevalence was 51.4 %, which was more prevalent in urban dwellers. The most common primary Headache type was Episodic Tension type Headache (prevalence; 24.5 %), followed by Episodic migraine (prevalence; 17.3 %), both types peaked in midlife. Headache disorders were more common in females with exception of cluster Headache that showed the expected male dominance. The risk of chronic Headache increased more than one fold and half when the participants were females, married, and in those with high education. More than 60 % of our participants did not seek medical advice for their Headaches problem; this percentage was higher in rural areas. Primary Headache disorders are common in Egypt; prevalence rate was comparable with western countries with exception of Episodic Tension Headache. Still Headache is under-estimated and under-recognized in Egypt and this problem should be targeted by health care providers.

  • Prevalence of primary Headache disorders in Fayoum Governorate, Egypt
    The Journal of Headache and Pain, 2015
    Co-Authors: Naglaa A. El-sherbiny, Mohamed Masoud, Nevin M Shalaby, Hatem S Shehata
    Abstract:

    Background There is abundance of epidemiological studies of Headache in developed and western countries; however, data in developing countries and in Egypt are still lacking. This study aims to detect the prevalence of primary Headache disorders in both urban and rural sectors in Fayoum governorate, Egypt. Methods A total of 2600 subjects were included using multi-stage stratified systematic random sampling, with respondent rate of 91.3 %. A pre-designed Arabic version, interviewer-administered, pilot tested structured questionnaire was developed according to The International Classification of Headache Disorders, 3rd edition (beta version), and this questionnaire was validated and the strength of agreement in Headache diagnosis was good. Results The 1-year Headache prevalence was 51.4 %, which was more prevalent in urban dwellers. The most common primary Headache type was Episodic Tension type Headache (prevalence; 24.5 %), followed by Episodic migraine (prevalence; 17.3 %), both types peaked in midlife. Headache disorders were more common in females with exception of cluster Headache that showed the expected male dominance. The risk of chronic Headache increased more than one fold and half when the participants were females, married, and in those with high education. More than 60 % of our participants did not seek medical advice for their Headaches problem; this percentage was higher in rural areas. Conclusions Primary Headache disorders are common in Egypt; prevalence rate was comparable with western countries with exception of Episodic Tension Headache. Still Headache is under-estimated and under-recognized in Egypt and this problem should be targeted by health care providers.

Naglaa A. El-sherbiny - One of the best experts on this subject based on the ideXlab platform.

  • Prevalence of primary Headache disorders in Fayoum Governorate, Egypt
    Journal of Headache and Pain, 2015
    Co-Authors: Naglaa A. El-sherbiny, Mohamed Masoud, Nevin M Shalaby, Hatem S Shehata
    Abstract:

    There is abundance of epidemiological studies of Headache in developed and western countries; however, data in developing countries and in Egypt are still lacking. This study aims to detect the prevalence of primary Headache disorders in both urban and rural sectors in Fayoum governorate, Egypt. A total of 2600 subjects were included using multi-stage stratified systematic random sampling, with respondent rate of 91.3 %. A pre-designed Arabic version, interviewer-administered, pilot tested structured questionnaire was developed according to The International Classification of Headache Disorders, 3rd edition (beta version), and this questionnaire was validated and the strength of agreement in Headache diagnosis was good. The 1-year Headache prevalence was 51.4 %, which was more prevalent in urban dwellers. The most common primary Headache type was Episodic Tension type Headache (prevalence; 24.5 %), followed by Episodic migraine (prevalence; 17.3 %), both types peaked in midlife. Headache disorders were more common in females with exception of cluster Headache that showed the expected male dominance. The risk of chronic Headache increased more than one fold and half when the participants were females, married, and in those with high education. More than 60 % of our participants did not seek medical advice for their Headaches problem; this percentage was higher in rural areas. Primary Headache disorders are common in Egypt; prevalence rate was comparable with western countries with exception of Episodic Tension Headache. Still Headache is under-estimated and under-recognized in Egypt and this problem should be targeted by health care providers.

  • Prevalence of primary Headache disorders in Fayoum Governorate, Egypt
    The Journal of Headache and Pain, 2015
    Co-Authors: Naglaa A. El-sherbiny, Mohamed Masoud, Nevin M Shalaby, Hatem S Shehata
    Abstract:

    Background There is abundance of epidemiological studies of Headache in developed and western countries; however, data in developing countries and in Egypt are still lacking. This study aims to detect the prevalence of primary Headache disorders in both urban and rural sectors in Fayoum governorate, Egypt. Methods A total of 2600 subjects were included using multi-stage stratified systematic random sampling, with respondent rate of 91.3 %. A pre-designed Arabic version, interviewer-administered, pilot tested structured questionnaire was developed according to The International Classification of Headache Disorders, 3rd edition (beta version), and this questionnaire was validated and the strength of agreement in Headache diagnosis was good. Results The 1-year Headache prevalence was 51.4 %, which was more prevalent in urban dwellers. The most common primary Headache type was Episodic Tension type Headache (prevalence; 24.5 %), followed by Episodic migraine (prevalence; 17.3 %), both types peaked in midlife. Headache disorders were more common in females with exception of cluster Headache that showed the expected male dominance. The risk of chronic Headache increased more than one fold and half when the participants were females, married, and in those with high education. More than 60 % of our participants did not seek medical advice for their Headaches problem; this percentage was higher in rural areas. Conclusions Primary Headache disorders are common in Egypt; prevalence rate was comparable with western countries with exception of Episodic Tension Headache. Still Headache is under-estimated and under-recognized in Egypt and this problem should be targeted by health care providers.

Nevin M Shalaby - One of the best experts on this subject based on the ideXlab platform.

  • Prevalence of primary Headache disorders in Fayoum Governorate, Egypt
    Journal of Headache and Pain, 2015
    Co-Authors: Naglaa A. El-sherbiny, Mohamed Masoud, Nevin M Shalaby, Hatem S Shehata
    Abstract:

    There is abundance of epidemiological studies of Headache in developed and western countries; however, data in developing countries and in Egypt are still lacking. This study aims to detect the prevalence of primary Headache disorders in both urban and rural sectors in Fayoum governorate, Egypt. A total of 2600 subjects were included using multi-stage stratified systematic random sampling, with respondent rate of 91.3 %. A pre-designed Arabic version, interviewer-administered, pilot tested structured questionnaire was developed according to The International Classification of Headache Disorders, 3rd edition (beta version), and this questionnaire was validated and the strength of agreement in Headache diagnosis was good. The 1-year Headache prevalence was 51.4 %, which was more prevalent in urban dwellers. The most common primary Headache type was Episodic Tension type Headache (prevalence; 24.5 %), followed by Episodic migraine (prevalence; 17.3 %), both types peaked in midlife. Headache disorders were more common in females with exception of cluster Headache that showed the expected male dominance. The risk of chronic Headache increased more than one fold and half when the participants were females, married, and in those with high education. More than 60 % of our participants did not seek medical advice for their Headaches problem; this percentage was higher in rural areas. Primary Headache disorders are common in Egypt; prevalence rate was comparable with western countries with exception of Episodic Tension Headache. Still Headache is under-estimated and under-recognized in Egypt and this problem should be targeted by health care providers.

  • Prevalence of primary Headache disorders in Fayoum Governorate, Egypt
    The Journal of Headache and Pain, 2015
    Co-Authors: Naglaa A. El-sherbiny, Mohamed Masoud, Nevin M Shalaby, Hatem S Shehata
    Abstract:

    Background There is abundance of epidemiological studies of Headache in developed and western countries; however, data in developing countries and in Egypt are still lacking. This study aims to detect the prevalence of primary Headache disorders in both urban and rural sectors in Fayoum governorate, Egypt. Methods A total of 2600 subjects were included using multi-stage stratified systematic random sampling, with respondent rate of 91.3 %. A pre-designed Arabic version, interviewer-administered, pilot tested structured questionnaire was developed according to The International Classification of Headache Disorders, 3rd edition (beta version), and this questionnaire was validated and the strength of agreement in Headache diagnosis was good. Results The 1-year Headache prevalence was 51.4 %, which was more prevalent in urban dwellers. The most common primary Headache type was Episodic Tension type Headache (prevalence; 24.5 %), followed by Episodic migraine (prevalence; 17.3 %), both types peaked in midlife. Headache disorders were more common in females with exception of cluster Headache that showed the expected male dominance. The risk of chronic Headache increased more than one fold and half when the participants were females, married, and in those with high education. More than 60 % of our participants did not seek medical advice for their Headaches problem; this percentage was higher in rural areas. Conclusions Primary Headache disorders are common in Egypt; prevalence rate was comparable with western countries with exception of Episodic Tension Headache. Still Headache is under-estimated and under-recognized in Egypt and this problem should be targeted by health care providers.

Mohamed Masoud - One of the best experts on this subject based on the ideXlab platform.

  • Prevalence of primary Headache disorders in Fayoum Governorate, Egypt
    Journal of Headache and Pain, 2015
    Co-Authors: Naglaa A. El-sherbiny, Mohamed Masoud, Nevin M Shalaby, Hatem S Shehata
    Abstract:

    There is abundance of epidemiological studies of Headache in developed and western countries; however, data in developing countries and in Egypt are still lacking. This study aims to detect the prevalence of primary Headache disorders in both urban and rural sectors in Fayoum governorate, Egypt. A total of 2600 subjects were included using multi-stage stratified systematic random sampling, with respondent rate of 91.3 %. A pre-designed Arabic version, interviewer-administered, pilot tested structured questionnaire was developed according to The International Classification of Headache Disorders, 3rd edition (beta version), and this questionnaire was validated and the strength of agreement in Headache diagnosis was good. The 1-year Headache prevalence was 51.4 %, which was more prevalent in urban dwellers. The most common primary Headache type was Episodic Tension type Headache (prevalence; 24.5 %), followed by Episodic migraine (prevalence; 17.3 %), both types peaked in midlife. Headache disorders were more common in females with exception of cluster Headache that showed the expected male dominance. The risk of chronic Headache increased more than one fold and half when the participants were females, married, and in those with high education. More than 60 % of our participants did not seek medical advice for their Headaches problem; this percentage was higher in rural areas. Primary Headache disorders are common in Egypt; prevalence rate was comparable with western countries with exception of Episodic Tension Headache. Still Headache is under-estimated and under-recognized in Egypt and this problem should be targeted by health care providers.

  • Prevalence of primary Headache disorders in Fayoum Governorate, Egypt
    The Journal of Headache and Pain, 2015
    Co-Authors: Naglaa A. El-sherbiny, Mohamed Masoud, Nevin M Shalaby, Hatem S Shehata
    Abstract:

    Background There is abundance of epidemiological studies of Headache in developed and western countries; however, data in developing countries and in Egypt are still lacking. This study aims to detect the prevalence of primary Headache disorders in both urban and rural sectors in Fayoum governorate, Egypt. Methods A total of 2600 subjects were included using multi-stage stratified systematic random sampling, with respondent rate of 91.3 %. A pre-designed Arabic version, interviewer-administered, pilot tested structured questionnaire was developed according to The International Classification of Headache Disorders, 3rd edition (beta version), and this questionnaire was validated and the strength of agreement in Headache diagnosis was good. Results The 1-year Headache prevalence was 51.4 %, which was more prevalent in urban dwellers. The most common primary Headache type was Episodic Tension type Headache (prevalence; 24.5 %), followed by Episodic migraine (prevalence; 17.3 %), both types peaked in midlife. Headache disorders were more common in females with exception of cluster Headache that showed the expected male dominance. The risk of chronic Headache increased more than one fold and half when the participants were females, married, and in those with high education. More than 60 % of our participants did not seek medical advice for their Headaches problem; this percentage was higher in rural areas. Conclusions Primary Headache disorders are common in Egypt; prevalence rate was comparable with western countries with exception of Episodic Tension Headache. Still Headache is under-estimated and under-recognized in Egypt and this problem should be targeted by health care providers.

Mario Giacovazzo - One of the best experts on this subject based on the ideXlab platform.

  • Alteration of central excitation circuits in chronic Headache and analgesic misuse.
    Headache, 1997
    Co-Authors: Bruno M. Fusco, Ornella Colantoni, Mario Giacovazzo
    Abstract:

    : Central excitatory circuits could be involved in the pathophysiology of pain; particularly, the genesis of chronic pain. The "second pain" is the sensation that follows the initial pain after an appropriate nociceptive stimulus. The second pain is amplified by repeating the stimulus after brief intervals (temporal summation). This phenomenon is the psychophysical correlate of the excitatory pain circuits. The temporal summation of the second pain was evaluated in four groups of subjects; one group affected by migraine without aura, one by Episodic Tension Headache, one by chronic daily Headache, and a group of healthy subjects. A percutaneous electrical shock was used as the nociceptive stimulus. The intensity of the second pain was significantly greater in the group of patients with chronic Headache in comparison with the other groups. The patients with chronic Headache were subdivided into three groups on the basis of their clinical history: a group with transformed migraine; a group with chronic Headache ab initio, a form related to the first one; (both groups suffered from chronic daily Headache with a frequent superimposition of episodes of migraine attacks) and the third group consisted of patients with chronic Tension Headache. The temporal summation of the second pain was altered in the first two groups. The patients with chronic migraine abused ergotamine given as a symptomatic drug. Those who were able to discontinue this drug were retested and reported a decrease of the second pain in comparison to the previous measurements. The results of the present study indicate that central excitatory circuits could be involved in the mechanism leading to the development of chronic daily Headache.

  • Inhibition of intercellular adhesion molecule-1 (ICAM-1), soluble ICAM-1 and interleukin-4 by nitric oxide expression in migraine patients
    Journal of Molecular Medicine, 1997
    Co-Authors: P. Martelletti, Giuseppe Stirparo, Stefania Morrone, Cristina Rinaldi, Mario Giacovazzo
    Abstract:

     The mechanisms of the postulated ”sterile” inflammation in migraine were studied utilizing flow cytometry (intercellular adhesion molecule 1, ICAM-1; interleukin-1 receptor, IL-1R) and enzyme-linked immunosorbent assay (soluble intercellular adhesion molecule 1, sICAM-1; interleukin-4, IL-4). Twenty patients suffering from migraine without aura, 20 healthy subjects, and 10 patients suffering from Episodic Tension Headache were selected. All of the migraine patients were studied during a migraine crisis experimentally induced by the administration of isosorbide dinitrate (a nitric oxide donor), and 10 out the 20 were also studied during a spontaneous migraine attack. A sharp decrease in the expression of ICAM-1 ( F =5.09, p