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Yongsoon Park - One of the best experts on this subject based on the ideXlab platform.
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Association of Blood Fatty Acid Composition and Dietary Pattern with the Risk of Non-Alcoholic Fatty Liver Disease in Patients Who Underwent Cholecystectomy.
Annals of nutrition & metabolism, 2017Co-Authors: Poyoung Shim, Dongho Choi, Yongsoon ParkAbstract:Background/aims The relationship between diet and non-alcoholic fatty liver disease (NAFLD) in patients with gallstone disease and in those who have a high risk for NAFLD has not been investigated. This study was conducted to investigate the association between the risk of NAFLD and dietary pattern in patients who underwent cholecystectomy. Additionally, we assessed the association between Erythrocyte fatty acid composition, a marker for diet, and the risk of NAFLD. Methods Patients (n = 139) underwent liver ultrasonography to determine the presence of NAFLD before laparoscopic cholecystectomy, reported dietary intake using food frequency questionnaire, and were assessed for blood fatty acid composition. Results Fifty-eight patients were diagnosed with NAFLD. The risk of NAFLD was negatively associated with 2 dietary patterns: consuming whole grain and legumes and consuming fish, vegetables, and fruit. NAFLD was positively associated with the consumption of refined grain, meat, processed meat, and fried foods. Additionally, the risk of NAFLD was positively associated with Erythrocyte Levels of 16:0 and 18:2t, while it was negatively associated with 20:5n3, 22:5n3, and Omega-3 Index. Conclusion The risk of NAFLD was negatively associated with a healthy dietary pattern of consuming whole grains, legumes, vegetables, fish, and fruit and with an Erythrocyte Level of n-3 polyunsaturated fatty acids rich in fish.
Poyoung Shim - One of the best experts on this subject based on the ideXlab platform.
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Association of Blood Fatty Acid Composition and Dietary Pattern with the Risk of Non-Alcoholic Fatty Liver Disease in Patients Who Underwent Cholecystectomy.
Annals of nutrition & metabolism, 2017Co-Authors: Poyoung Shim, Dongho Choi, Yongsoon ParkAbstract:Background/aims The relationship between diet and non-alcoholic fatty liver disease (NAFLD) in patients with gallstone disease and in those who have a high risk for NAFLD has not been investigated. This study was conducted to investigate the association between the risk of NAFLD and dietary pattern in patients who underwent cholecystectomy. Additionally, we assessed the association between Erythrocyte fatty acid composition, a marker for diet, and the risk of NAFLD. Methods Patients (n = 139) underwent liver ultrasonography to determine the presence of NAFLD before laparoscopic cholecystectomy, reported dietary intake using food frequency questionnaire, and were assessed for blood fatty acid composition. Results Fifty-eight patients were diagnosed with NAFLD. The risk of NAFLD was negatively associated with 2 dietary patterns: consuming whole grain and legumes and consuming fish, vegetables, and fruit. NAFLD was positively associated with the consumption of refined grain, meat, processed meat, and fried foods. Additionally, the risk of NAFLD was positively associated with Erythrocyte Levels of 16:0 and 18:2t, while it was negatively associated with 20:5n3, 22:5n3, and Omega-3 Index. Conclusion The risk of NAFLD was negatively associated with a healthy dietary pattern of consuming whole grains, legumes, vegetables, fish, and fruit and with an Erythrocyte Level of n-3 polyunsaturated fatty acids rich in fish.
Didac Mauricio - One of the best experts on this subject based on the ideXlab platform.
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Lower hemoglobin concentration is associated with retinal ischemia and the severity of diabetic retinopathy in type 2 diabetes
Journal of diabetes research, 2016Co-Authors: Alicia Traveset, Esther Rubinat, Emilio Ortega, Nuria Alcubierre, Beatriz Esquivel Vázquez, Marta Hernández, Carmen Jurjo, Ramon Espinet, Juan Antonio Ezpeleta, Didac MauricioAbstract:Aims. To assess the association of blood oxygen-transport capacity variables with the prevalence of diabetic retinopathy (DR), retinal ischemia, and macular oedema in patients with type 2 diabetes mellitus (T2DM). Methods. Cross-sectional, case-control study (N = 312) with T2DM: 153 individuals with DR and 159 individuals with no DR. Participants were classified according to the severity of DR and the presence of retinal ischemia or macular oedema. Hematological variables were collected by standardized methods. Three logistic models were adjusted to ascertain the association between hematologic variables with the severity of DR and the presence of retinal ischemia or macular oedema. Results. Individuals with severe DR showed significantly lower hemoglobin, hematocrit, and Erythrocyte Levels compared with those with mild disease and in individuals with retinal ischemia and macular oedema compared with those without these disorders. Hemoglobin was the only factor that showed a significant inverse association with the severity of DR [beta-coefficient = -0.52, P value = 0.003] and retinal ischemia [beta-coefficient = -0.49, P value = 0.001]. Lower Erythrocyte Level showed a marginally significant association with macular oedema [beta-coefficient = -0.86, P value = 0.055]. Conclusions. In patients with DR, low blood oxygen-transport capacity was associated with more severe DR and the presence of retinal ischemia. Low hemoglobin Levels may have a key role in the development and progression of DR.
Dongho Choi - One of the best experts on this subject based on the ideXlab platform.
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Association of Blood Fatty Acid Composition and Dietary Pattern with the Risk of Non-Alcoholic Fatty Liver Disease in Patients Who Underwent Cholecystectomy.
Annals of nutrition & metabolism, 2017Co-Authors: Poyoung Shim, Dongho Choi, Yongsoon ParkAbstract:Background/aims The relationship between diet and non-alcoholic fatty liver disease (NAFLD) in patients with gallstone disease and in those who have a high risk for NAFLD has not been investigated. This study was conducted to investigate the association between the risk of NAFLD and dietary pattern in patients who underwent cholecystectomy. Additionally, we assessed the association between Erythrocyte fatty acid composition, a marker for diet, and the risk of NAFLD. Methods Patients (n = 139) underwent liver ultrasonography to determine the presence of NAFLD before laparoscopic cholecystectomy, reported dietary intake using food frequency questionnaire, and were assessed for blood fatty acid composition. Results Fifty-eight patients were diagnosed with NAFLD. The risk of NAFLD was negatively associated with 2 dietary patterns: consuming whole grain and legumes and consuming fish, vegetables, and fruit. NAFLD was positively associated with the consumption of refined grain, meat, processed meat, and fried foods. Additionally, the risk of NAFLD was positively associated with Erythrocyte Levels of 16:0 and 18:2t, while it was negatively associated with 20:5n3, 22:5n3, and Omega-3 Index. Conclusion The risk of NAFLD was negatively associated with a healthy dietary pattern of consuming whole grains, legumes, vegetables, fish, and fruit and with an Erythrocyte Level of n-3 polyunsaturated fatty acids rich in fish.
Turková A - One of the best experts on this subject based on the ideXlab platform.
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The role of erythrocytapheresis in secondary erythrocytosis therapy.
Clinical hemorheology and microcirculation, 2002Co-Authors: Milan Blaha, Skorepová M, Masín, Spásová I, Paráková Z, Jaroslav Malý, Pavel Zak, David Belada, Turková AAbstract:Clinic of Pneumology, Charles University, Hradec Kralove, Czech RepublicDear Sirs,We were very interested in the article of Pollari et al., 1999 [2] published in your journal. We alsoperform large volume erythrocytapheresis (LVE) for more than 20 years. According to data reported byG. Pollari, we evaluated the group of our patients and were pleased to find that our principal results werevery similar – however some details and experience are different.We agree that in secondary polyglobulia the mechanism increasing hemoglobin Level is in most casesreasonable, but then develops the situation when we have also found an inconvenient increase in bloodviscosity, due to Erythrocyte aggregation, and in peripheral resistance. In these cases, hemoglobin reduc-tion is justifiable and brings relief to the patient when other methods fail.Phlebotomy could be useful, but LVE offers several advantages: it is bulky but quick and sometimesonly a single procedure maintaines the patient’s condition for a considerable period of time. From themedical point of view, LVE is not just a primitive removal of whole blood that does not save plasmaproteins and other factors present in plasma (clotting factors, hormones, complement, “reactants ofearly phase”, sometimes even drugs as demonstrates the case of our patients treated successfuly withantiepileptic drugs whose condition worsened probably after repeated relatively large volume phle-botomy). The aim of LVE is to remove only “pathogenic” blood elements – Erythrocytes.For several years now, we carry out about 1000 therapeutic hemaphereses per year, out of which LVEaccounted for 5–10%. We assessed the effects of LVE in 80 patients treated over 5 last years, on average4 procedures per 1 patient, total number of procedures being 339. Basic data are shown in Table 1. In con-trast with the report of Pollari et al. [2], our group includes patients with polycythemia vera and patientswith secondary polyglobulia, which, in some of them developes after renal transplantation. The causes ofthis type of polyglobulia are not known but polyglobulia is observed up to 20% of patients, mostly onlyduring a limited period of time. We wish to stress here that LVE, especially for posttransplant patients, isrecommandable, because if Erythrocyte Level extremely increases, there is the risk of thrombosis and incase of its progression, there is the risk of renal veins thrombosis resulting in transplantation failure. Inthis situation, a quick success as LVE offers, is the treatment of choice.