The Experts below are selected from a list of 621 Experts worldwide ranked by ideXlab platform
Marie-jeanne P. Gerritsen - One of the best experts on this subject based on the ideXlab platform.
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The current role of in vivo reflectance confocal microscopy within the continuum of actinic keratosis and squamous cell carcinoma: a systematic review
European Journal of Dermatology, 2016Co-Authors: Kim P. Nguyen, Malou Peppelman, Lisa Hoogedoorn, Marie-jeanne P. GerritsenAbstract:Background Clinical differentiation between actinic keratosis (AK), squamous cell carcinoma (SCC) in situ , and invasiveSCCand its variants may be difficult. Reflectance confocal microscopy (RCM) is a noninvasive technique for in vivo skin imaging. Objectives To explicate the diagnostic and monitoring use of RCM within the spectrum of AK and SCC, and evaluate the accuracy of RCM for these diagnoses relative to histopathology. Materials & methods A systematic literature search was performed in PubMed, EMBASE, the Cochrane Library, and Web of Science databases. The quality was assessed using the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) checklist. Results Twenty-five eligible studies were included. Different diagnostic RCM features have been described for AK, actinic cheilitis (AC), Erythroplasia of Queyrat, Bowen disease, invasive SCC, and keratoacanthoma (KA). The overall range of sensitivity and specificity of RCM for the diagnosis of SCC, AK, SCC in situ , and KA was 79-100% and 78-100%, respectively. Conclusion The current literature describes the use ofRCMfor diagnosing AK,AC, Erythroplasia of Queyrat, Bowen disease, invasive SCC, and KA, as well as for monitoring treatments of AK, with good accuracy. Unfortunately, studies with high method-ological quality are lacking. Pre-treatment of hyperkeratotic lesions and uniform definitions of RCM features are required to simplify the differentiation between AKs, SCC in situ , and SCC and its variants in clinical practice.
Kim P. Nguyen - One of the best experts on this subject based on the ideXlab platform.
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The current role of in vivo reflectance confocal microscopy within the continuum of actinic keratosis and squamous cell carcinoma: a systematic review
European Journal of Dermatology, 2016Co-Authors: Kim P. Nguyen, Malou Peppelman, Lisa Hoogedoorn, Marie-jeanne P. GerritsenAbstract:Background Clinical differentiation between actinic keratosis (AK), squamous cell carcinoma (SCC) in situ , and invasiveSCCand its variants may be difficult. Reflectance confocal microscopy (RCM) is a noninvasive technique for in vivo skin imaging. Objectives To explicate the diagnostic and monitoring use of RCM within the spectrum of AK and SCC, and evaluate the accuracy of RCM for these diagnoses relative to histopathology. Materials & methods A systematic literature search was performed in PubMed, EMBASE, the Cochrane Library, and Web of Science databases. The quality was assessed using the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) checklist. Results Twenty-five eligible studies were included. Different diagnostic RCM features have been described for AK, actinic cheilitis (AC), Erythroplasia of Queyrat, Bowen disease, invasive SCC, and keratoacanthoma (KA). The overall range of sensitivity and specificity of RCM for the diagnosis of SCC, AK, SCC in situ , and KA was 79-100% and 78-100%, respectively. Conclusion The current literature describes the use ofRCMfor diagnosing AK,AC, Erythroplasia of Queyrat, Bowen disease, invasive SCC, and KA, as well as for monitoring treatments of AK, with good accuracy. Unfortunately, studies with high method-ological quality are lacking. Pre-treatment of hyperkeratotic lesions and uniform definitions of RCM features are required to simplify the differentiation between AKs, SCC in situ , and SCC and its variants in clinical practice.
Lisa Hoogedoorn - One of the best experts on this subject based on the ideXlab platform.
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The current role of in vivo reflectance confocal microscopy within the continuum of actinic keratosis and squamous cell carcinoma: a systematic review
European Journal of Dermatology, 2016Co-Authors: Kim P. Nguyen, Malou Peppelman, Lisa Hoogedoorn, Marie-jeanne P. GerritsenAbstract:Background Clinical differentiation between actinic keratosis (AK), squamous cell carcinoma (SCC) in situ , and invasiveSCCand its variants may be difficult. Reflectance confocal microscopy (RCM) is a noninvasive technique for in vivo skin imaging. Objectives To explicate the diagnostic and monitoring use of RCM within the spectrum of AK and SCC, and evaluate the accuracy of RCM for these diagnoses relative to histopathology. Materials & methods A systematic literature search was performed in PubMed, EMBASE, the Cochrane Library, and Web of Science databases. The quality was assessed using the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) checklist. Results Twenty-five eligible studies were included. Different diagnostic RCM features have been described for AK, actinic cheilitis (AC), Erythroplasia of Queyrat, Bowen disease, invasive SCC, and keratoacanthoma (KA). The overall range of sensitivity and specificity of RCM for the diagnosis of SCC, AK, SCC in situ , and KA was 79-100% and 78-100%, respectively. Conclusion The current literature describes the use ofRCMfor diagnosing AK,AC, Erythroplasia of Queyrat, Bowen disease, invasive SCC, and KA, as well as for monitoring treatments of AK, with good accuracy. Unfortunately, studies with high method-ological quality are lacking. Pre-treatment of hyperkeratotic lesions and uniform definitions of RCM features are required to simplify the differentiation between AKs, SCC in situ , and SCC and its variants in clinical practice.
Malou Peppelman - One of the best experts on this subject based on the ideXlab platform.
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The current role of in vivo reflectance confocal microscopy within the continuum of actinic keratosis and squamous cell carcinoma: a systematic review
European Journal of Dermatology, 2016Co-Authors: Kim P. Nguyen, Malou Peppelman, Lisa Hoogedoorn, Marie-jeanne P. GerritsenAbstract:Background Clinical differentiation between actinic keratosis (AK), squamous cell carcinoma (SCC) in situ , and invasiveSCCand its variants may be difficult. Reflectance confocal microscopy (RCM) is a noninvasive technique for in vivo skin imaging. Objectives To explicate the diagnostic and monitoring use of RCM within the spectrum of AK and SCC, and evaluate the accuracy of RCM for these diagnoses relative to histopathology. Materials & methods A systematic literature search was performed in PubMed, EMBASE, the Cochrane Library, and Web of Science databases. The quality was assessed using the STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) checklist. Results Twenty-five eligible studies were included. Different diagnostic RCM features have been described for AK, actinic cheilitis (AC), Erythroplasia of Queyrat, Bowen disease, invasive SCC, and keratoacanthoma (KA). The overall range of sensitivity and specificity of RCM for the diagnosis of SCC, AK, SCC in situ , and KA was 79-100% and 78-100%, respectively. Conclusion The current literature describes the use ofRCMfor diagnosing AK,AC, Erythroplasia of Queyrat, Bowen disease, invasive SCC, and KA, as well as for monitoring treatments of AK, with good accuracy. Unfortunately, studies with high method-ological quality are lacking. Pre-treatment of hyperkeratotic lesions and uniform definitions of RCM features are required to simplify the differentiation between AKs, SCC in situ , and SCC and its variants in clinical practice.
Anthony Hall - One of the best experts on this subject based on the ideXlab platform.
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penile intraepithelial neoplasia Erythroplasia of queyrat bowen s disease
2019Co-Authors: Anthony HallAbstract:Penile intraepithelial neoplasia (PIN) is in situ squamous cell carcinoma of the male genitalia with no invasion into the dermis or lymphovascular system. Penile intraepithelial neoplasia has three variants: Erythroplasia of Queyrat, Bowen’s disease (Bowen disease), and bowenoid papulosis. The distinction between Bowen’s disease of the penis and Erythroplasia of Queyrat is historical. Bowen’s disease of the penis is in situ squamous cell carcinoma (SCC) of genital hair-bearing skin (the penile shaft or scrotum) (Fig. 50.1). Erythroplasia of Queyrat is in situ SCC of the glans penis or of the mucosal aspect of the foreskin in uncircumcised men (Figs. 50.2, 50.3, 50.4, and 50.5). The term Erythroplasia of Queyrat could be abandoned, as it is a subset of male genital Bowen’s disease and both are encompassed within penile intraepithelial neoplasia [1]. Bowenoid papulosis exhibits different biologic behaviour from penile Bowen’s disease and Erythroplasia of Queyrat and is discussed separately in Chap. 51.
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Penile Intraepithelial Neoplasia (Erythroplasia of Queyrat, Bowen’s Disease)
Atlas of Male Genital Dermatology, 2018Co-Authors: Anthony HallAbstract:Penile intraepithelial neoplasia (PIN) is in situ squamous cell carcinoma of the male genitalia with no invasion into the dermis or lymphovascular system. Penile intraepithelial neoplasia has three variants: Erythroplasia of Queyrat, Bowen’s disease (Bowen disease), and bowenoid papulosis. The distinction between Bowen’s disease of the penis and Erythroplasia of Queyrat is historical. Bowen’s disease of the penis is in situ squamous cell carcinoma (SCC) of genital hair-bearing skin (the penile shaft or scrotum) (Fig. 50.1). Erythroplasia of Queyrat is in situ SCC of the glans penis or of the mucosal aspect of the foreskin in uncircumcised men (Figs. 50.2, 50.3, 50.4, and 50.5). The term Erythroplasia of Queyrat could be abandoned, as it is a subset of male genital Bowen’s disease and both are encompassed within penile intraepithelial neoplasia [1]. Bowenoid papulosis exhibits different biologic behaviour from penile Bowen’s disease and Erythroplasia of Queyrat and is discussed separately in Chap. 51.