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George Triadafilopoulos - One of the best experts on this subject based on the ideXlab platform.

  • Endoscopic Treatments for Dysplastic Barrett’s Esophagus: Resection, Ablation, What Else?
    World Journal of Surgery, 2015
    Co-Authors: Charumathi Raghu Subramanian, George Triadafilopoulos
    Abstract:

    Background Endoscopic eradication therapy for dysplastic Barrett’s Esophagus (BE) comprises Resection and mucosal ablation techniques. Over the years, these techniques have been tried with success, not only for dysplastic Barrett’s epithelium but also for non-dysplastic Barrett’s epithelium and early adenocarcinoma. Endoscopic Resection is usually carried out for visible lesions, either as endoscopic mucosal Resection (EMR), which is practiced widely in Western countries, or as endoscopic submucosal dissection, which is more popular in Japan and throughout Asia. Among ablative techniques are photodynamic therapy, cryotherapy, and radiofrequency ablation (RFA). Methods We reviewed the published evidence pertaining to endoscopic treatments of dysplastic BE, with emphasis on the various Resection and ablative techniques, their safety, efficacy, durability of effect, and tolerability. Results Both Resection and ablation procedures performed endoscopically have been proved effective, and safe for treating dysplastic BE and early adenocarcinoma. Among the ablative techniques, RFA has shown to be more effective and safe, and is preferred for most cases. Conclusions Endoscopic therapies have revolutionized the treatment of BE and have minimized the need for surgical intervention in many patients. Concomitant treatment of acid reflux with proton pump inhibitors and continuous surveillance are essential. Combination techniques such as EMR followed by RFA may be also considered in some cases.

  • endoscopic treatments for dysplastic barrett s Esophagus Resection ablation what else
    World Journal of Surgery, 2015
    Co-Authors: Charumathi Raghu Subramanian, George Triadafilopoulos
    Abstract:

    Background Endoscopic eradication therapy for dysplastic Barrett’s Esophagus (BE) comprises Resection and mucosal ablation techniques. Over the years, these techniques have been tried with success, not only for dysplastic Barrett’s epithelium but also for non-dysplastic Barrett’s epithelium and early adenocarcinoma. Endoscopic Resection is usually carried out for visible lesions, either as endoscopic mucosal Resection (EMR), which is practiced widely in Western countries, or as endoscopic submucosal dissection, which is more popular in Japan and throughout Asia. Among ablative techniques are photodynamic therapy, cryotherapy, and radiofrequency ablation (RFA).

  • Endoscopic Treatments for Dysplastic Barrett’s Esophagus: Resection, Ablation, What Else?
    World Journal of Surgery, 2014
    Co-Authors: Charumathi Raghu Subramanian, George Triadafilopoulos
    Abstract:

    Background Endoscopic eradication therapy for dysplastic Barrett’s Esophagus (BE) comprises Resection and mucosal ablation techniques. Over the years, these techniques have been tried with success, not only for dysplastic Barrett’s epithelium but also for non-dysplastic Barrett’s epithelium and early adenocarcinoma. Endoscopic Resection is usually carried out for visible lesions, either as endoscopic mucosal Resection (EMR), which is practiced widely in Western countries, or as endoscopic submucosal dissection, which is more popular in Japan and throughout Asia. Among ablative techniques are photodynamic therapy, cryotherapy, and radiofrequency ablation (RFA).

Charumathi Raghu Subramanian - One of the best experts on this subject based on the ideXlab platform.

  • Endoscopic Treatments for Dysplastic Barrett’s Esophagus: Resection, Ablation, What Else?
    World Journal of Surgery, 2015
    Co-Authors: Charumathi Raghu Subramanian, George Triadafilopoulos
    Abstract:

    Background Endoscopic eradication therapy for dysplastic Barrett’s Esophagus (BE) comprises Resection and mucosal ablation techniques. Over the years, these techniques have been tried with success, not only for dysplastic Barrett’s epithelium but also for non-dysplastic Barrett’s epithelium and early adenocarcinoma. Endoscopic Resection is usually carried out for visible lesions, either as endoscopic mucosal Resection (EMR), which is practiced widely in Western countries, or as endoscopic submucosal dissection, which is more popular in Japan and throughout Asia. Among ablative techniques are photodynamic therapy, cryotherapy, and radiofrequency ablation (RFA). Methods We reviewed the published evidence pertaining to endoscopic treatments of dysplastic BE, with emphasis on the various Resection and ablative techniques, their safety, efficacy, durability of effect, and tolerability. Results Both Resection and ablation procedures performed endoscopically have been proved effective, and safe for treating dysplastic BE and early adenocarcinoma. Among the ablative techniques, RFA has shown to be more effective and safe, and is preferred for most cases. Conclusions Endoscopic therapies have revolutionized the treatment of BE and have minimized the need for surgical intervention in many patients. Concomitant treatment of acid reflux with proton pump inhibitors and continuous surveillance are essential. Combination techniques such as EMR followed by RFA may be also considered in some cases.

  • endoscopic treatments for dysplastic barrett s Esophagus Resection ablation what else
    World Journal of Surgery, 2015
    Co-Authors: Charumathi Raghu Subramanian, George Triadafilopoulos
    Abstract:

    Background Endoscopic eradication therapy for dysplastic Barrett’s Esophagus (BE) comprises Resection and mucosal ablation techniques. Over the years, these techniques have been tried with success, not only for dysplastic Barrett’s epithelium but also for non-dysplastic Barrett’s epithelium and early adenocarcinoma. Endoscopic Resection is usually carried out for visible lesions, either as endoscopic mucosal Resection (EMR), which is practiced widely in Western countries, or as endoscopic submucosal dissection, which is more popular in Japan and throughout Asia. Among ablative techniques are photodynamic therapy, cryotherapy, and radiofrequency ablation (RFA).

  • Endoscopic Treatments for Dysplastic Barrett’s Esophagus: Resection, Ablation, What Else?
    World Journal of Surgery, 2014
    Co-Authors: Charumathi Raghu Subramanian, George Triadafilopoulos
    Abstract:

    Background Endoscopic eradication therapy for dysplastic Barrett’s Esophagus (BE) comprises Resection and mucosal ablation techniques. Over the years, these techniques have been tried with success, not only for dysplastic Barrett’s epithelium but also for non-dysplastic Barrett’s epithelium and early adenocarcinoma. Endoscopic Resection is usually carried out for visible lesions, either as endoscopic mucosal Resection (EMR), which is practiced widely in Western countries, or as endoscopic submucosal dissection, which is more popular in Japan and throughout Asia. Among ablative techniques are photodynamic therapy, cryotherapy, and radiofrequency ablation (RFA).

W. T. Broek - One of the best experts on this subject based on the ideXlab platform.

  • Anesthesiological hazards during laparoscopic transhiatal esophageal Resection: a case control study of the laparoscopic-assisted vs the conventional approach
    Surgical Endoscopy And Other Interventional Techniques, 2004
    Co-Authors: Ö. Makay, W. T. Broek, J. Z. Yuan, D. P. Veerman, D. W. H. Helfferich, M. A. Cuesta
    Abstract:

    Background Interest for minimal invasive approach of Esophagus Resection is increasing. Today, a minimally invasive transhiatal esophagectomy is possible and is accepted widespread. Since cardiopulmonary changes during laparoscopic dissection of the mediastinum has not been studied yet we assessed the anesthesiological consequences of pneumothorax during laparoscopic mediastinal dissection. Methods In this case control study, 25 laparoscopically assisted transhiatal espohagus Resections were compared with a control group consisting of 20 open transhiatal Esophagus Resections. Patient characteristics and intraoperative haemodynamic, respiratory, and ventilatory parameters were assessed. Results The laparoscopic assisted procedure was performed successfully in 12 of the 20 patients. The duration of the laparoscopic assisted procedure, compared to the open group was significantly longer (p

  • Anesthesiological hazards during laparoscopic transhiatal esophageal Resection: a case control study of the laparoscopic-assisted vs the conventional approach.
    Surgical Endoscopy and Other Interventional Techniques, 2004
    Co-Authors: Özer Makay, W. T. Broek, J. Z. Yuan, D. P. Veerman, D. W. H. Helfferich, Miguel A. Cuesta
    Abstract:

    Background Interest for minimal invasive approach of Esophagus Resection is increasing. Today, a minimally invasive transhiatal esophagectomy is possible and is accepted widespread. Since cardiopulmonary changes during laparoscopic dissection of the mediastinum has not been studied yet we assessed the anesthesiological consequences of pneumothorax during laparoscopic mediastinal dissection.

  • Laparoscopically assisted transhiatal Resection for malignancies of the distal Esophagus
    Surgical Endoscopy And Other Interventional Techniques, 2004
    Co-Authors: W. T. Broek, Ö. Makay, F. J. Berends, J. Z. Yuan, A. P. J. Houdijk, S. Meijer, M. A. Cuesta
    Abstract:

    Background Resection of the Esophagus remains the only curative therapy for esophageal cancer. Conventional Resections are right-side thoracotomy in combination with laparotomy, gastric tube creation, and the transhiatal approach according to Orringer. This study evaluated laparoscopically assisted transhiatal Esophagus Resection, which offers perfect visualization of the Esophagus during mediastinal dissection without the necessity of a thoracotomy. Methods In this study, 25 laparoscopically assisted transhiatal Esophagus Resections were compared with a historical control group consisting of 20 open transhiatal Esophagus Resections. Results Nine laparoscopically assisted Resections (36%) were converted to open procedures. The operating time was longer in the laparoscopically assisted group (300 vs 257 min; p < 0.05), but laparoscopically assisted Esophagus Resection was associated with less blood loss (600 vs 900 ml; p < 0.05) and shorter intensive care unit stay (1 vs 2 days; p < 0.05). There were no differences in morbidity, mortality, and hosptital stay. During a shorter follow-up time for the laparoscopic group (17 vs 54 months), 11 patients (44%) in the laparoscopically assisted group and 10 (50%) patients in the open group had recurrence of the disease. Conclusions Laparoscopically assisted transhiatal Esophagus Resection is a safe procedure with important advantages, as compared with the open procedure, such as less blood loss and shorter intensive care unit stay. At this point, the oncologic consequences are not clear.

  • laparoscopically assisted transhiatal Resection for malignancies of the distal Esophagus
    Surgical Endoscopy and Other Interventional Techniques, 2004
    Co-Authors: W. T. Broek, F. J. Berends, J. Z. Yuan, A. P. J. Houdijk, S. Meijer, Özer Makay, Miguel A. Cuesta
    Abstract:

    Background Resection of the Esophagus remains the only curative therapy for esophageal cancer. Conventional Resections are right-side thoracotomy in combination with laparotomy, gastric tube creation, and the transhiatal approach according to Orringer. This study evaluated laparoscopically assisted transhiatal Esophagus Resection, which offers perfect visualization of the Esophagus during mediastinal dissection without the necessity of a thoracotomy.

M. A. Cuesta - One of the best experts on this subject based on the ideXlab platform.

  • Anesthesiological hazards during laparoscopic transhiatal esophageal Resection: a case control study of the laparoscopic-assisted vs the conventional approach
    Surgical Endoscopy And Other Interventional Techniques, 2004
    Co-Authors: Ö. Makay, W. T. Broek, J. Z. Yuan, D. P. Veerman, D. W. H. Helfferich, M. A. Cuesta
    Abstract:

    Background Interest for minimal invasive approach of Esophagus Resection is increasing. Today, a minimally invasive transhiatal esophagectomy is possible and is accepted widespread. Since cardiopulmonary changes during laparoscopic dissection of the mediastinum has not been studied yet we assessed the anesthesiological consequences of pneumothorax during laparoscopic mediastinal dissection. Methods In this case control study, 25 laparoscopically assisted transhiatal espohagus Resections were compared with a control group consisting of 20 open transhiatal Esophagus Resections. Patient characteristics and intraoperative haemodynamic, respiratory, and ventilatory parameters were assessed. Results The laparoscopic assisted procedure was performed successfully in 12 of the 20 patients. The duration of the laparoscopic assisted procedure, compared to the open group was significantly longer (p

  • Laparoscopically assisted transhiatal Resection for malignancies of the distal Esophagus
    Surgical Endoscopy And Other Interventional Techniques, 2004
    Co-Authors: W. T. Broek, Ö. Makay, F. J. Berends, J. Z. Yuan, A. P. J. Houdijk, S. Meijer, M. A. Cuesta
    Abstract:

    Background Resection of the Esophagus remains the only curative therapy for esophageal cancer. Conventional Resections are right-side thoracotomy in combination with laparotomy, gastric tube creation, and the transhiatal approach according to Orringer. This study evaluated laparoscopically assisted transhiatal Esophagus Resection, which offers perfect visualization of the Esophagus during mediastinal dissection without the necessity of a thoracotomy. Methods In this study, 25 laparoscopically assisted transhiatal Esophagus Resections were compared with a historical control group consisting of 20 open transhiatal Esophagus Resections. Results Nine laparoscopically assisted Resections (36%) were converted to open procedures. The operating time was longer in the laparoscopically assisted group (300 vs 257 min; p < 0.05), but laparoscopically assisted Esophagus Resection was associated with less blood loss (600 vs 900 ml; p < 0.05) and shorter intensive care unit stay (1 vs 2 days; p < 0.05). There were no differences in morbidity, mortality, and hosptital stay. During a shorter follow-up time for the laparoscopic group (17 vs 54 months), 11 patients (44%) in the laparoscopically assisted group and 10 (50%) patients in the open group had recurrence of the disease. Conclusions Laparoscopically assisted transhiatal Esophagus Resection is a safe procedure with important advantages, as compared with the open procedure, such as less blood loss and shorter intensive care unit stay. At this point, the oncologic consequences are not clear.

Johan F Lange - One of the best experts on this subject based on the ideXlab platform.

  • vascular anatomy of the stomach related to gastric tube construction
    Diseases of The Esophagus, 2008
    Co-Authors: M Buunen, P P G M Rooijens, H J Smaal, Gertjan Kleinrensink, E Van Der Harst, H W Tilanus, Johan F Lange
    Abstract:

    In view of constructing a gastric tube after Esophagus Resection, the vascular anatomy of the greater curvature of the stomach, especially the connection between the left and right gastro-epiploic arteries, was investigated. The vascular anatomy was studied in 20 embalmed human specimens. After dissection a gastric tube of 4 cm wide was constructed, using the greater gastric curvature. Various lengths of the arterial arcades were measured. In 70% an anastomosis between the right and left gastro-epiploic arteries was present. With the construction of an isoperistaltic gastric tube, in which the left gastro-epiploic artery is left in situ (ligating it at the splenic hilus), there is an 18.7% increase of length of arterial arcade along the gastric tube. Leaving the left gastro-epiploic artery in situ increases the feeding arterial arcaded-length along the gastric tube with 5.0 cm (19%).

  • Vascular anatomy of the stomach related to gastric tube construction
    Diseases of The Esophagus, 2008
    Co-Authors: M Buunen, P P G M Rooijens, H J Smaal, Gertjan Kleinrensink, E Van Der Harst, H W Tilanus, Johan F Lange
    Abstract:

    In view of constructing a gastric tube after Esophagus Resection, the vascular anatomy of the greater curvature of the stomach, especially the connection between the left and right gastro-epiploic arteries, was investigated. The vascular anatomy was studied in 20 embalmed human specimens. After dissection a gastric tube of 4 cm wide was constructed, using the greater gastric curvature. Various lengths of the arterial arcades were measured. In 70% an anastomosis between the right and left gastro-epiploic arteries was present. With the construction of an isoperistaltic gastric tube, in which the left gastro-epiploic artery is left in situ (ligating it at the splenic hilus), there is an 18.7% increase of length of arterial arcade along the gastric tube. Leaving the left gastro-epiploic artery in situ increases the feeding arterial arcaded-length along the gastric tube with 5.0 cm (19%). © 2007 The Authors Journal compilation