The Experts below are selected from a list of 10656 Experts worldwide ranked by ideXlab platform
M H Shyr - One of the best experts on this subject based on the ideXlab platform.
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high resolution human leukocyte antigen hla haplotypes and linkage disequilibrium of hla b and c and hla drb1 and dqb1 alleles in a taiwanese population
Human Immunology, 2009Co-Authors: Kuoliang Yang, Sheeping Chen, M H Shyr, P Y LinAbstract:Using the maximum-likelihood method with the expectation-maximization (EM) algorithm of PYPOP, high-resolution human leukocyte antigen (HLA) three-locus haplotypes (HLA-A, -B, and -C; HLA-A, -B, and -DRB1) and four-locus haplotypes (HLA-A, -B, -C, and -DRB1) were determined. Linkage disequilibrium of high-resolution HLA-B and -C alleles and HLA-DRB1 and -DQB1 alleles was also calculated. Comparison of the Taiwanese haplotypes and haplotypes from donors in the Chinese Han population, the Asia Pacific Islander Ethnic Category of the NMDP (National Marrow Donor Program), and the Taiwanese cord blood units demonstrated similarities and dissimilarities among the four populations. HLA allele frequencies of our study suggested that the Taiwanese have a relative population relationship with the southern Han Chinese with regard to HLA. Our results also indicated that the Taiwanese population exhibits genetic proximity with Asian Americans with regard to HLA-A and -DRB1 but not HLA-B.
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high resolution human leukocyte antigen hla haplotypes and linkage disequilibrium of hla b and c and hla drb1 and dqb1 alleles in a taiwanese population
Human Immunology, 2009Co-Authors: Kuoliang Yang, Sheeping Chen, M H ShyrAbstract:Using the maximum-likelihood method with the expectation-maximization (EM) algorithm of PYPOP, high-resolution human leukocyte antigen (HLA) three-locus haplotypes (HLA-A, -B, and -C; HLA-A, -B, and -DRB1) and four-locus haplotypes (HLA-A, -B, -C, and -DRB1) were determined. Linkage disequilibrium of high-resolution HLA-B and -C alleles and HLA-DRB1 and -DQB1 alleles was also calculated. Comparison of the Taiwanese haplotypes and haplotypes from donors in the Chinese Han population, the Asia Pacific Islander Ethnic Category of the NMDP (National Marrow Donor Program), and the Taiwanese cord blood units demonstrated similarities and dissimilarities among the four populations. HLA allele frequencies of our study suggested that the Taiwanese have a relative population relationship with the southern Han Chinese with regard to HLA. Our results also indicated that the Taiwanese population exhibits genetic proximity with Asian Americans with regard to HLA-A and -DRB1 but not HLA-B.
Kuoliang Yang - One of the best experts on this subject based on the ideXlab platform.
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high resolution human leukocyte antigen hla haplotypes and linkage disequilibrium of hla b and c and hla drb1 and dqb1 alleles in a taiwanese population
Human Immunology, 2009Co-Authors: Kuoliang Yang, Sheeping Chen, M H Shyr, P Y LinAbstract:Using the maximum-likelihood method with the expectation-maximization (EM) algorithm of PYPOP, high-resolution human leukocyte antigen (HLA) three-locus haplotypes (HLA-A, -B, and -C; HLA-A, -B, and -DRB1) and four-locus haplotypes (HLA-A, -B, -C, and -DRB1) were determined. Linkage disequilibrium of high-resolution HLA-B and -C alleles and HLA-DRB1 and -DQB1 alleles was also calculated. Comparison of the Taiwanese haplotypes and haplotypes from donors in the Chinese Han population, the Asia Pacific Islander Ethnic Category of the NMDP (National Marrow Donor Program), and the Taiwanese cord blood units demonstrated similarities and dissimilarities among the four populations. HLA allele frequencies of our study suggested that the Taiwanese have a relative population relationship with the southern Han Chinese with regard to HLA. Our results also indicated that the Taiwanese population exhibits genetic proximity with Asian Americans with regard to HLA-A and -DRB1 but not HLA-B.
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high resolution human leukocyte antigen hla haplotypes and linkage disequilibrium of hla b and c and hla drb1 and dqb1 alleles in a taiwanese population
Human Immunology, 2009Co-Authors: Kuoliang Yang, Sheeping Chen, M H ShyrAbstract:Using the maximum-likelihood method with the expectation-maximization (EM) algorithm of PYPOP, high-resolution human leukocyte antigen (HLA) three-locus haplotypes (HLA-A, -B, and -C; HLA-A, -B, and -DRB1) and four-locus haplotypes (HLA-A, -B, -C, and -DRB1) were determined. Linkage disequilibrium of high-resolution HLA-B and -C alleles and HLA-DRB1 and -DQB1 alleles was also calculated. Comparison of the Taiwanese haplotypes and haplotypes from donors in the Chinese Han population, the Asia Pacific Islander Ethnic Category of the NMDP (National Marrow Donor Program), and the Taiwanese cord blood units demonstrated similarities and dissimilarities among the four populations. HLA allele frequencies of our study suggested that the Taiwanese have a relative population relationship with the southern Han Chinese with regard to HLA. Our results also indicated that the Taiwanese population exhibits genetic proximity with Asian Americans with regard to HLA-A and -DRB1 but not HLA-B.
P Y Lin - One of the best experts on this subject based on the ideXlab platform.
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high resolution human leukocyte antigen hla haplotypes and linkage disequilibrium of hla b and c and hla drb1 and dqb1 alleles in a taiwanese population
Human Immunology, 2009Co-Authors: Kuoliang Yang, Sheeping Chen, M H Shyr, P Y LinAbstract:Using the maximum-likelihood method with the expectation-maximization (EM) algorithm of PYPOP, high-resolution human leukocyte antigen (HLA) three-locus haplotypes (HLA-A, -B, and -C; HLA-A, -B, and -DRB1) and four-locus haplotypes (HLA-A, -B, -C, and -DRB1) were determined. Linkage disequilibrium of high-resolution HLA-B and -C alleles and HLA-DRB1 and -DQB1 alleles was also calculated. Comparison of the Taiwanese haplotypes and haplotypes from donors in the Chinese Han population, the Asia Pacific Islander Ethnic Category of the NMDP (National Marrow Donor Program), and the Taiwanese cord blood units demonstrated similarities and dissimilarities among the four populations. HLA allele frequencies of our study suggested that the Taiwanese have a relative population relationship with the southern Han Chinese with regard to HLA. Our results also indicated that the Taiwanese population exhibits genetic proximity with Asian Americans with regard to HLA-A and -DRB1 but not HLA-B.
Sheeping Chen - One of the best experts on this subject based on the ideXlab platform.
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high resolution human leukocyte antigen hla haplotypes and linkage disequilibrium of hla b and c and hla drb1 and dqb1 alleles in a taiwanese population
Human Immunology, 2009Co-Authors: Kuoliang Yang, Sheeping Chen, M H Shyr, P Y LinAbstract:Using the maximum-likelihood method with the expectation-maximization (EM) algorithm of PYPOP, high-resolution human leukocyte antigen (HLA) three-locus haplotypes (HLA-A, -B, and -C; HLA-A, -B, and -DRB1) and four-locus haplotypes (HLA-A, -B, -C, and -DRB1) were determined. Linkage disequilibrium of high-resolution HLA-B and -C alleles and HLA-DRB1 and -DQB1 alleles was also calculated. Comparison of the Taiwanese haplotypes and haplotypes from donors in the Chinese Han population, the Asia Pacific Islander Ethnic Category of the NMDP (National Marrow Donor Program), and the Taiwanese cord blood units demonstrated similarities and dissimilarities among the four populations. HLA allele frequencies of our study suggested that the Taiwanese have a relative population relationship with the southern Han Chinese with regard to HLA. Our results also indicated that the Taiwanese population exhibits genetic proximity with Asian Americans with regard to HLA-A and -DRB1 but not HLA-B.
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high resolution human leukocyte antigen hla haplotypes and linkage disequilibrium of hla b and c and hla drb1 and dqb1 alleles in a taiwanese population
Human Immunology, 2009Co-Authors: Kuoliang Yang, Sheeping Chen, M H ShyrAbstract:Using the maximum-likelihood method with the expectation-maximization (EM) algorithm of PYPOP, high-resolution human leukocyte antigen (HLA) three-locus haplotypes (HLA-A, -B, and -C; HLA-A, -B, and -DRB1) and four-locus haplotypes (HLA-A, -B, -C, and -DRB1) were determined. Linkage disequilibrium of high-resolution HLA-B and -C alleles and HLA-DRB1 and -DQB1 alleles was also calculated. Comparison of the Taiwanese haplotypes and haplotypes from donors in the Chinese Han population, the Asia Pacific Islander Ethnic Category of the NMDP (National Marrow Donor Program), and the Taiwanese cord blood units demonstrated similarities and dissimilarities among the four populations. HLA allele frequencies of our study suggested that the Taiwanese have a relative population relationship with the southern Han Chinese with regard to HLA. Our results also indicated that the Taiwanese population exhibits genetic proximity with Asian Americans with regard to HLA-A and -DRB1 but not HLA-B.
Retrovirus Epidemiology Donor Study - One of the best experts on this subject based on the ideXlab platform.
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abo and rh d phenotype frequencies of different racial Ethnic groups in the united states
Transfusion, 2004Co-Authors: George Garratty, Simone A Glynn, Robin Mcentire, Retrovirus Epidemiology Donor StudyAbstract:BACKGROUND: Commonly quoted ABO/Rh(D) frequencies in the US are usually from relatively small studies with racial or Ethnic categories often judged by name or appearance. STUDY DESIGN AND METHODS: A 10-year demo-graphic database that contained racial or Ethnic and ABO/Rh(D) phenotype data on 3.1 million allogeneic and autologous donors giving blood at five blood centers in the US was used to compute ABO and Rh(D) phenotypes in various racial/Ethnic groups. The racial or Ethnic Category was designated by the donor. RESULTS: The highest percentage of Group O was found in Hispanic (56.5%), North American Indian (54.6%), and black non-Hispanic (50.2%) donors. Hispanic and black non-Hispanic donors had a much lower percentage (7.3 and 7.1%, respectively) of Rh– compared to white non-Hispanic donors (17.3%). Group O Rh– and Group B Rh– were found more commonly (8.0 and 1.8%, respectively) in white non-Hispanic donors than in Hispanic (3.9 and 0.7%), black non-Hispanic (3.6 and 1.3%), and Asian (0.7 and 0.4%) donors. CONCLUSIONS: These data confirmed that the highest percentages of ORh+, BRh+/ABRh+, and Rh– are present in Hispanic, Asian, and white non-Hispanic donors, respectively. These are the largest and most accurate data of ABO/Rh(D) phenotype frequencies for the major racial/Ethnic donor groups in the US.