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Bofeng Zhu - One of the best experts on this subject based on the ideXlab platform.

  • genetic polymorphisms of 54 mitochondrial dna snp loci in chinese xibe Ethnic Minority Group
    Scientific Reports, 2017
    Co-Authors: Chunmei Shen, Bofeng Zhu, Chunhua Yang, Caiyong Yin, Haotian Meng, Yuxin Guo, Ting Mei, Feng Chen
    Abstract:

    We analyzed the genetic polymorphisms of 54 mitochondrial DNA (mtDNA) variants in Chinese Xibe Ethnic Minority Group. A total of 137 unrelated healthy volunteers from Chinese Xibe Group were the objects of our study. Among the selected loci, there were 51 variable positions including transitions and transversions, and single nucleotide transitions were common (83.93%) versus transversions. These variations defined 64 different mtDNA haplotypes exclusive of (CA)n and 9 bp deletion variation. The haplotype diversity and discrimination power in Xibe population were 0.9800 ± 0.004 and 0.9699, respectively. Besides, we compared Xibe Group with 18 other populations and reconstructed a phylogenetic tree using Neighbor-Joining method. The result revealed that Xibe Group was a close to Xinjiang Han and Yanbian Korean Groups. Our data also indicated that Xibe Group has a close relationship with Daur and Ewenki Groups, which is reflected by the history that Xibe was influenced by Daur and Ewenki Groups during the development of these Groups. In conclusion, the variants we studied are polymorphic and could be used as informative genetic markers for forensic and population genetic application.

  • allelic frequency distributions of 21 non combined dna index system str loci in a russian Ethnic Minority Group from inner mongolia china
    Journal of Zhejiang University-science B, 2013
    Co-Authors: Hongdan Wang, Chunmei Shen, Wenjuan Liu, Yudang Zhang, Guang Yang, Jiangwei Yan, Haixia Qin, Bofeng Zhu
    Abstract:

    We studied the allelic frequency distributions and statistical forensic parameters of 21 new short tandem repeat (STR) loci and the amelogenin locus, which are not included in the combined DNA index system (CODIS), in a Russian Ethnic Minority Group from the Inner Mongolia Autonomous Region, China. A total of 114 bloodstain samples from unrelated individuals were extracted and co-amplified with four fluorescence-labeled primers in a multiplex polymerase chain reaction (PCR) system. Using capillary electrophoresis, the PCR products of the 21 STR loci were separated and genotyped. A total of 161 alleles were observed in the Russian Ethnic Minority Group, and corresponding allelic frequencies ranged from 0.0044 to 0.5965. The 21 non-CODIS STR loci of the Russian Ethnic Minority Group were characterized by high genetic diversity and therefore may be useful for elucidating the population’s genetic background, for individual identification, and for paternity testing in forensic practice.

  • killer cell immunoglobulin like receptor gene diversity in the tibetan Ethnic Minority Group of china
    Human Immunology, 2010
    Co-Authors: Bofeng Zhu, Hongdan Wang, Chunmei Shen, Guang Yang, Haixia Qin, Yajun Deng, Ping Huang, Shuan Liang Fan, Li Bin Deng, Rudolf Lucas
    Abstract:

    Abstract The aim of this study was to analyze killer immunoglobulin-like receptor (KIR) gene polymorphisms in the Tibetan Ethnic Minority of China. To that purpose, we have studied KIR gene frequencies and genotype diversities of 16 KIR genes and three pseudogenes (2DL1, 2DL2, 2DL3, 2DL4, 2DL5A, 2DL5B, 2DS1, 2DS2, 2DS3, 2DS4*001/002, 2DS4*003-007, 2DS5, 3DL1, 3DL2, 3DL3, 3DS1, 2DP1, 3DP1*001/002/004, and 3DP1*003) in a population sample of 102 unrelated healthy individuals of the Tibetan population living in Lhasa city, Tibet Autonomous Region of China. Tibetans mainly live in “the roof of the world,” the Qinghai–Tibet Plateau of China and surrounding areas stretching from central Asia in the North and West to Myanmar and mainland China in the East, and India, Nepal, and Bhutan to the south. KIR gene frequencies and statistical parameters of Tibetan Ethnic Minority were calculated. Fifteen KIR genes were observed in the 102 tested Tibetan individuals with different frequencies. The allelic frequencies of the 15 KIR genes ranged from 0.06 to 0.86. In addition, KIR 2DL1, 2DL4, 3DL2, and 3DL3 were found to be present in every individual. Variable gene content, together with allelic polymorphisms, can result in individualized human KIR genotypes and haplotypes, with the A haplotypes being predominantly observed. The results of tested linkage disequilibrium (LD) among KIR genes demonstrated that KIR genes present a wide range of linkage disequilibrium. Moreover, a comparison of the population data of our study with previously published population data of other Ethnic Groups or areas was performed. The differences of allelic frequency distribution in KIR2DL2, 2DL3, 2DL5, 3DL1, 2DS1, 2DS2, 2DS3, 3DS1, and 2DP1 were statistically significant among different populations using the statistical method of the standard χ 2 test. In conclusion, the results of the present study can be valuable for enriching the Chinese Ethnical gene information resources of the KIR gene pool and for anthological studies, as well as for KIR-related disease research.

  • population data of 15 str loci of chinese yi Ethnic Minority Group
    Legal Medicine, 2008
    Co-Authors: Bofeng Zhu, Chunmei Shen, Yajun Deng
    Abstract:

    Abstract Allele frequency data and statistical parameters for D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA loci were determined in a sample of 120 healthy unrelated individuals of Chinese Yi Ethnic Minority Group living in Yunnan province, China. We observed 132 alleles with allelic frequencies ranging from 0.0042 to 0.5333. The forensic statistical parameters from the data of all the loci showed high values. All loci were in accordance with Hardy–Weinberg equilibrium ( p >0.05). The obtained frequency distributions were compared with previously published other population data, and significant differences were found between Yi population and Korean, Chinese Tibetan, Uigur, Ewenki, Han, Hui population at some STR loci. Our results of present study were valuable for forensic application and Chinese population genetic studies. These population data enriched Chinese genetic informational resources.

  • genetic analysis of 17 y chromosomal strs haplotypes of chinese tibetan Ethnic Group residing in qinghai province of china
    Forensic Science International, 2008
    Co-Authors: Bofeng Zhu, Chunmei Shen, Xi Xun, Yajun Deng, Tiehong Yang, Yingfang Tian, Jincheng Yan
    Abstract:

    Abstract We have co-amplified and analyzed 17 Y-chromosomal STRs loci including European ‘extended haplotypes' (DYS19, DYS389 I, DYS389 II, DYS390, DYS391, DYS392, DYS393, DYS385a,b, DYS438, and DYS439) and also six additional loci DYS437, DYS448, DYS456, DYS458, DYS635 and YGATA H4 in a population sample of 167 healthy unrelated autochthonous male individuals of Chinese Tibetan Ethnic Minority Group residing in Qinghai province of China using a multiplex PCR system. The gene diversity values for the Y-STRs loci ranged from a minimum 0.3581 for DYS391 locus to a maximum of 0.8702 for DYS385a,b loci in Tibetan population. A total of 163 haplotypes were identified in the set of Y-STR loci, of which 159 were unique and 4 found in two individuals. The overall haplotype diversity for the set of Y-STRs loci was 0.9998, and the discrimination capacity was 0.9938. Research results will be valuable for human identification and paternity tests in the region and for Chinese population genetic study in the future.

Chunmei Shen - One of the best experts on this subject based on the ideXlab platform.

  • genetic polymorphisms of 54 mitochondrial dna snp loci in chinese xibe Ethnic Minority Group
    Scientific Reports, 2017
    Co-Authors: Chunmei Shen, Bofeng Zhu, Chunhua Yang, Caiyong Yin, Haotian Meng, Yuxin Guo, Ting Mei, Feng Chen
    Abstract:

    We analyzed the genetic polymorphisms of 54 mitochondrial DNA (mtDNA) variants in Chinese Xibe Ethnic Minority Group. A total of 137 unrelated healthy volunteers from Chinese Xibe Group were the objects of our study. Among the selected loci, there were 51 variable positions including transitions and transversions, and single nucleotide transitions were common (83.93%) versus transversions. These variations defined 64 different mtDNA haplotypes exclusive of (CA)n and 9 bp deletion variation. The haplotype diversity and discrimination power in Xibe population were 0.9800 ± 0.004 and 0.9699, respectively. Besides, we compared Xibe Group with 18 other populations and reconstructed a phylogenetic tree using Neighbor-Joining method. The result revealed that Xibe Group was a close to Xinjiang Han and Yanbian Korean Groups. Our data also indicated that Xibe Group has a close relationship with Daur and Ewenki Groups, which is reflected by the history that Xibe was influenced by Daur and Ewenki Groups during the development of these Groups. In conclusion, the variants we studied are polymorphic and could be used as informative genetic markers for forensic and population genetic application.

  • genetic profile characterization and population study of 21 autosomal str in chinese kazak Ethnic Minority Group
    Electrophoresis, 2014
    Co-Authors: Jingyi Yuan, Hongdan Wang, Chunmei Shen, Wenjuan Liu, Yudang Zhang, Guang Yang, Jiangwei Yan, Xiaoye Wang, Yanli Wang, Haotian Meng
    Abstract:

    Short tandem repeat loci have been recognized as useful tools in the routine forensic application and in recent decades, more and more new short tandem repeat (STR) loci have been constantly discovered, studied, and applied in forensic caseworks. In this study, we investigated the genetic polymorphisms of 21 STR loci in the Kazak Ethnic Minority as well as the genetic relationships between the Kazak Ethnic Minority and other populations. Allelic frequencies of 21 STR loci were obtained from 114 unrelated healthy Kazak individuals in the Ili Kazak Autonomous Prefecture, Xinjiang Uigur Autonomous Region of China. We observed a total of 159 alleles in the Group with the allelic diversity values ranging from 0.0044 to 0.5088. The highest polymorphism was found at D19S433 locus and the lowest was found at D1S1627. Statistical analysis of the generated data indicated no deviation from Hardy-Weinberg equilibriums at all 21 STR loci. In order to estimate the population differentiation, allelic frequencies of all STR loci of the Kazak were compared with those of other neighboring populations using analysis of molecular variance method. Statistically significant differences were found between the studied population and other populations at 2-7 STR loci. A neighbor-joining tree was constructed based on allelic frequencies of the 21 STR loci and phylogenetic analysis indicates that the Kazak has a close genetic relationship with the Uigur Ethnic Group. The present results may provide useful information for forensic sciences and population genetics studies, and can also increase our understanding of the genetic background of this Group. The present findings showed that all the 21 STR loci are highly genetically polymorphic in the Kazak Group, which provided valuable population genetic data for the genetic information study, forensic human individual identification, and paternity tests.

  • allelic frequency distributions of 21 non combined dna index system str loci in a russian Ethnic Minority Group from inner mongolia china
    Journal of Zhejiang University-science B, 2013
    Co-Authors: Hongdan Wang, Chunmei Shen, Wenjuan Liu, Yudang Zhang, Guang Yang, Jiangwei Yan, Haixia Qin, Bofeng Zhu
    Abstract:

    We studied the allelic frequency distributions and statistical forensic parameters of 21 new short tandem repeat (STR) loci and the amelogenin locus, which are not included in the combined DNA index system (CODIS), in a Russian Ethnic Minority Group from the Inner Mongolia Autonomous Region, China. A total of 114 bloodstain samples from unrelated individuals were extracted and co-amplified with four fluorescence-labeled primers in a multiplex polymerase chain reaction (PCR) system. Using capillary electrophoresis, the PCR products of the 21 STR loci were separated and genotyped. A total of 161 alleles were observed in the Russian Ethnic Minority Group, and corresponding allelic frequencies ranged from 0.0044 to 0.5965. The 21 non-CODIS STR loci of the Russian Ethnic Minority Group were characterized by high genetic diversity and therefore may be useful for elucidating the population’s genetic background, for individual identification, and for paternity testing in forensic practice.

  • genetic diversities of 21 non codis autosomal strs of a chinese tibetan Ethnic Minority Group in lhasa
    International Journal of Legal Medicine, 2011
    Co-Authors: Chunmei Shen, Hongdan Wang, Guang Yang, Jingfeng Huang, Hang Jing
    Abstract:

    In the present study, we investigated 21 short tandem repeat (STR) loci (D6S474, D12ATA63, D22S1045, D10S1248, D1S1677, D11S4463, D1S1627, D3S4529, D2S441, D6S1017, D4S2408, D19S433, D17S1301, D1GATA113, D18S853, D20S482, D14S1434, D9S1122, D2S1776, D10S1435, D5S2500), which are not included in the Combined DNA Index System and Amelogenin locus in 104 randomly selected healthy autochthonous individuals from the Tibetan Ethnic Minority Group residing in the Lhasa region, Tibet Autonomous Region of China. Allelic frequencies, common forensic statistical parameters, and the Hardy–Weinberg equilibrium in this population were calculated with a modified PowerState V12.xls. A total of 143 alleles were found in the Tibetan Group with corresponding allelic frequencies ranging from 0.005 to 0.582. The observed heterozygosity, the expected heterozygosity, the power of discrimination, the power of exclusion, and the polymorphic information content ranged from 0.615 to 0.817, 0.559 to 0.787, 0.727 to 0.926, 0.310 to 0.632, and 0.488 to 0.760, respectively. Chi-square tests of the observed genotype frequencies and expected genotype frequencies in the samples showed no departure from the Hardy–Weinberg equilibrium at all loci except for D5S2500. Our results demonstrate that these 21 STRs are highly polymorphic and suitable for anthropological research, population genetics, and forensic paternity testing and human individual identification in this region, and can enrich Chinese Ethnical genetic informational resources.

  • killer cell immunoglobulin like receptor gene diversity in the tibetan Ethnic Minority Group of china
    Human Immunology, 2010
    Co-Authors: Bofeng Zhu, Hongdan Wang, Chunmei Shen, Guang Yang, Haixia Qin, Yajun Deng, Ping Huang, Shuan Liang Fan, Li Bin Deng, Rudolf Lucas
    Abstract:

    Abstract The aim of this study was to analyze killer immunoglobulin-like receptor (KIR) gene polymorphisms in the Tibetan Ethnic Minority of China. To that purpose, we have studied KIR gene frequencies and genotype diversities of 16 KIR genes and three pseudogenes (2DL1, 2DL2, 2DL3, 2DL4, 2DL5A, 2DL5B, 2DS1, 2DS2, 2DS3, 2DS4*001/002, 2DS4*003-007, 2DS5, 3DL1, 3DL2, 3DL3, 3DS1, 2DP1, 3DP1*001/002/004, and 3DP1*003) in a population sample of 102 unrelated healthy individuals of the Tibetan population living in Lhasa city, Tibet Autonomous Region of China. Tibetans mainly live in “the roof of the world,” the Qinghai–Tibet Plateau of China and surrounding areas stretching from central Asia in the North and West to Myanmar and mainland China in the East, and India, Nepal, and Bhutan to the south. KIR gene frequencies and statistical parameters of Tibetan Ethnic Minority were calculated. Fifteen KIR genes were observed in the 102 tested Tibetan individuals with different frequencies. The allelic frequencies of the 15 KIR genes ranged from 0.06 to 0.86. In addition, KIR 2DL1, 2DL4, 3DL2, and 3DL3 were found to be present in every individual. Variable gene content, together with allelic polymorphisms, can result in individualized human KIR genotypes and haplotypes, with the A haplotypes being predominantly observed. The results of tested linkage disequilibrium (LD) among KIR genes demonstrated that KIR genes present a wide range of linkage disequilibrium. Moreover, a comparison of the population data of our study with previously published population data of other Ethnic Groups or areas was performed. The differences of allelic frequency distribution in KIR2DL2, 2DL3, 2DL5, 3DL1, 2DS1, 2DS2, 2DS3, 3DS1, and 2DP1 were statistically significant among different populations using the statistical method of the standard χ 2 test. In conclusion, the results of the present study can be valuable for enriching the Chinese Ethnical gene information resources of the KIR gene pool and for anthological studies, as well as for KIR-related disease research.

Yao Liu - One of the best experts on this subject based on the ideXlab platform.

  • genetic polymorphisms of 15 str in chinese salar Ethnic Minority Group
    Forensic Science International, 2007
    Co-Authors: Chunmei Shen, Jun Zhu, Yao Liu, Jie Zhao
    Abstract:

    Abstract Allele frequency data for 15 STR loci, namely D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA, were obtained from a sample of 258 healthy unrelated individuals of Salar population in China. All loci were in Hardy–Weinberg equilibrium. After comparing, significant differences were found between the Salar and Miao, Uigur, Han, Korean, Belgian, Byelorussian population at some loci. The results demonstrate that the loci are useful for forensic human identification and parentage testing.

  • population genetic polymorphisms for 17 y chromosomal strs haplotypes of chinese salar Ethnic Minority Group
    Legal Medicine, 2007
    Co-Authors: Chunmei Shen, Jiangwei Yan, Bofeng Zhu, Xi Xun, Yajun Deng, Jun Zhu, Yao Liu
    Abstract:

    We studied and established a DNA database of 17 Y-STRs in a population sample of 133 unrelated individuals of Salar Ethnic Minority Group, in order to investigate haplotype frequencies of Salar population, evaluate their usefulness in forensic applications, and enrich Chinese population genetic informational resources. Out of a total of 133 individuals 123 showed different haplotypes, while six haplotypes occurred more than once. The overall haplotype diversity for the Y-STRs loci was 0.9983, and the discrimination capacity was 0.9248.

  • population genetics for y chromosomal strs haplotypes of chinese tibetan Ethnic Minority Group in tibet
    Forensic Science International, 2006
    Co-Authors: Bofeng Zhu, Jun Zhu, Shunzhi Liu, Jingfeng Huang, Youcai Wang, Liping Chen, Qianzi Zhao, Yao Liu
    Abstract:

    Y-chromosomal STRs loci were analyzed from a sample of 119 healthy unrelated autochthonous male individuals of Chinese Tibetan Ethnic Minority Group using a multiplex PCR system. Allele and haplotype frequencies for DYS19, DYS389 I, DYS389 II, DYS390, DYS391, DYS392, DYS393, DYS385a,b, DYS438, and DYS439 were determined by the Y-PLEXtrade mark 12 kit. The gene diversity values for the Y-STRs loci ranged from 0.3347 (DYS438) to 0.9547 (DYS385a,b). A total of 110 haplotypes were identified in the Y-STR loci, among which 104 were unique, while six occurred more than once. The overall haplotype diversity for the Y-STRs loci was 0.9981, and the discrimination capacity was 0.9897. The results in the present study can be used for routine forensic application in the region, and enrich Chinese Ethnical genetic informational resources.

  • genetic polymorphisms for 11 y strs haplotypes of chinese yi Ethnic Minority Group
    Forensic Science International, 2006
    Co-Authors: Bofeng Zhu, Chunmei Shen, Jun Zhu, Qianzi Zhao, Guangli Qian, Ruiyi Shi, Yonghui Dang, Ping Huang, Yao Liu
    Abstract:

    Eleven Y-STRs loci including minimal haplotypes (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, and DYS385a,b) and two additional loci, namely DYS438 and DYS439 have been co-amplified in 100 healthy unrelated males of Chinese Yi Minority Ethnic Group using the Y-PLEX™ 5 and Y-PLEX™ 6 kit, in order to investigate allele and haplotype frequencies of Yi population, evaluate their usefulness in forensic paternity testing and human identification, and enrich Chinese population genetic informational resources. Out of a total of 100 individuals 85 showed different haplotypes, while 8 haplotypes occurred more than once. The overall haplotype diversity for 11 Y-STRs loci was 0.9945.

  • population genetics for y strs haplotypes of chinese ewenki Ethnic Minority Group
    Journal of Forensic Sciences, 2005
    Co-Authors: Bofeng Zhu, Chunmei Shen, Jun Zhu, Zhaozhong Gong, Gong Yang, Jie Zhao, Yao Liu
    Abstract:

    Chinese Ewenki Ethnic Minority Group, with a population of 26,300 in a statistical survey conducted in 2000, has a lifestyle of nomad, and is distributed across seven counties in the Inner Mongolia Autonomous Region and in Nahe County of Heilongjiang Province of China. The Ewenki people have no written script but a spoken language with three dialects belonging to the Manchu-Tungusic Group of the Altai language family. Raising reindeers is the key livelihood of Ewenkis.

Yajun Deng - One of the best experts on this subject based on the ideXlab platform.

  • killer cell immunoglobulin like receptor gene diversity in the tibetan Ethnic Minority Group of china
    Human Immunology, 2010
    Co-Authors: Bofeng Zhu, Hongdan Wang, Chunmei Shen, Guang Yang, Haixia Qin, Yajun Deng, Ping Huang, Shuan Liang Fan, Li Bin Deng, Rudolf Lucas
    Abstract:

    Abstract The aim of this study was to analyze killer immunoglobulin-like receptor (KIR) gene polymorphisms in the Tibetan Ethnic Minority of China. To that purpose, we have studied KIR gene frequencies and genotype diversities of 16 KIR genes and three pseudogenes (2DL1, 2DL2, 2DL3, 2DL4, 2DL5A, 2DL5B, 2DS1, 2DS2, 2DS3, 2DS4*001/002, 2DS4*003-007, 2DS5, 3DL1, 3DL2, 3DL3, 3DS1, 2DP1, 3DP1*001/002/004, and 3DP1*003) in a population sample of 102 unrelated healthy individuals of the Tibetan population living in Lhasa city, Tibet Autonomous Region of China. Tibetans mainly live in “the roof of the world,” the Qinghai–Tibet Plateau of China and surrounding areas stretching from central Asia in the North and West to Myanmar and mainland China in the East, and India, Nepal, and Bhutan to the south. KIR gene frequencies and statistical parameters of Tibetan Ethnic Minority were calculated. Fifteen KIR genes were observed in the 102 tested Tibetan individuals with different frequencies. The allelic frequencies of the 15 KIR genes ranged from 0.06 to 0.86. In addition, KIR 2DL1, 2DL4, 3DL2, and 3DL3 were found to be present in every individual. Variable gene content, together with allelic polymorphisms, can result in individualized human KIR genotypes and haplotypes, with the A haplotypes being predominantly observed. The results of tested linkage disequilibrium (LD) among KIR genes demonstrated that KIR genes present a wide range of linkage disequilibrium. Moreover, a comparison of the population data of our study with previously published population data of other Ethnic Groups or areas was performed. The differences of allelic frequency distribution in KIR2DL2, 2DL3, 2DL5, 3DL1, 2DS1, 2DS2, 2DS3, 3DS1, and 2DP1 were statistically significant among different populations using the statistical method of the standard χ 2 test. In conclusion, the results of the present study can be valuable for enriching the Chinese Ethnical gene information resources of the KIR gene pool and for anthological studies, as well as for KIR-related disease research.

  • population data of 15 str loci of chinese yi Ethnic Minority Group
    Legal Medicine, 2008
    Co-Authors: Bofeng Zhu, Chunmei Shen, Yajun Deng
    Abstract:

    Abstract Allele frequency data and statistical parameters for D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA loci were determined in a sample of 120 healthy unrelated individuals of Chinese Yi Ethnic Minority Group living in Yunnan province, China. We observed 132 alleles with allelic frequencies ranging from 0.0042 to 0.5333. The forensic statistical parameters from the data of all the loci showed high values. All loci were in accordance with Hardy–Weinberg equilibrium ( p >0.05). The obtained frequency distributions were compared with previously published other population data, and significant differences were found between Yi population and Korean, Chinese Tibetan, Uigur, Ewenki, Han, Hui population at some STR loci. Our results of present study were valuable for forensic application and Chinese population genetic studies. These population data enriched Chinese genetic informational resources.

  • genetic polymorphism of mitochondrial dna hvs i and hvs ii of chinese tu Ethnic Minority Group
    Journal of Genetics and Genomics, 2008
    Co-Authors: Feng Chen, Yajun Deng, Yonghui Dang, Bo Zhang, Chunxia Yan, Teng Chen
    Abstract:

    We analyzed the two hypervariable segments HVS-I and HVS-II of 108 Chinese Tu Ethnic Minority Group samples for forensic and population genetics purposes. Comparing with Anderson sequence, 79 polymorphic loci in HVS-I and 40 in HVS-II were found in Chinese Tu Ethnic Minority Group mtDNA sequences, and 90 and 64 haplotypes were then defined. Haplotype diversity and the mean pairwise differences were 0.9903+/-0.0013 and 5.7785 in HVS-I, and 0.9777+/-0.0013 and 3.5819 in HVS-II, respectively. By analyzing the hypervariable domain from nucleotide 1,6180 to 1,6193 in HVS-I, we defined some new types of sequence variations. We also compared the relationship between Tu population and other populations using mtDNA HVS-I sequences. According to Rst genetic distances, the phylogenetic tree showed that the Tu population, the Xi'an Han population, the Chinese Korean, and the Mongol Ethnic Group were in a clade. This indicated a close genetic relationship between them. There were far relations between the Tu population and other Chinese southern Han populations, Siberian, European, African, and other foreign populations. The results suggest that Tu population has a multi-origin and has also merged with other local populations.

  • genetic analysis of 17 y chromosomal strs haplotypes of chinese tibetan Ethnic Group residing in qinghai province of china
    Forensic Science International, 2008
    Co-Authors: Bofeng Zhu, Chunmei Shen, Xi Xun, Yajun Deng, Tiehong Yang, Yingfang Tian, Jincheng Yan
    Abstract:

    Abstract We have co-amplified and analyzed 17 Y-chromosomal STRs loci including European ‘extended haplotypes' (DYS19, DYS389 I, DYS389 II, DYS390, DYS391, DYS392, DYS393, DYS385a,b, DYS438, and DYS439) and also six additional loci DYS437, DYS448, DYS456, DYS458, DYS635 and YGATA H4 in a population sample of 167 healthy unrelated autochthonous male individuals of Chinese Tibetan Ethnic Minority Group residing in Qinghai province of China using a multiplex PCR system. The gene diversity values for the Y-STRs loci ranged from a minimum 0.3581 for DYS391 locus to a maximum of 0.8702 for DYS385a,b loci in Tibetan population. A total of 163 haplotypes were identified in the set of Y-STR loci, of which 159 were unique and 4 found in two individuals. The overall haplotype diversity for the set of Y-STRs loci was 0.9998, and the discrimination capacity was 0.9938. Research results will be valuable for human identification and paternity tests in the region and for Chinese population genetic study in the future.

  • population genetic analysis of 15 str loci of chinese tu Ethnic Minority Group
    Forensic Science International, 2008
    Co-Authors: Bofeng Zhu, Chunmei Shen, Jiangwei Yan, Yajun Deng, Xin Xiong, Yanqing Huang
    Abstract:

    We studied and established a DNA database of 15 euchromosome STRs (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA) in a population sample of 151 unrelated individuals of Tu Ethnic Minority Group. Allelic frequencies and statistical parameters of Tu population were calculated. Totally 136 alleles were observed, with the corresponding allelic frequencies ranging from 0.0033 to 0.5359. Chi-square test showed that all STR loci agreed with Hardy-Weinberg equilibrium. Our study population data were compared with the previously publishing population data of other Ethnic Groups or areas. Our results of present study were valuable for human identification and paternity tests in Chinese Tu population.

Jun Zhu - One of the best experts on this subject based on the ideXlab platform.

  • genetic polymorphisms of 15 str in chinese salar Ethnic Minority Group
    Forensic Science International, 2007
    Co-Authors: Chunmei Shen, Jun Zhu, Yao Liu, Jie Zhao
    Abstract:

    Abstract Allele frequency data for 15 STR loci, namely D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA, were obtained from a sample of 258 healthy unrelated individuals of Salar population in China. All loci were in Hardy–Weinberg equilibrium. After comparing, significant differences were found between the Salar and Miao, Uigur, Han, Korean, Belgian, Byelorussian population at some loci. The results demonstrate that the loci are useful for forensic human identification and parentage testing.

  • population genetic polymorphisms for 17 y chromosomal strs haplotypes of chinese salar Ethnic Minority Group
    Legal Medicine, 2007
    Co-Authors: Chunmei Shen, Jiangwei Yan, Bofeng Zhu, Xi Xun, Yajun Deng, Jun Zhu, Yao Liu
    Abstract:

    We studied and established a DNA database of 17 Y-STRs in a population sample of 133 unrelated individuals of Salar Ethnic Minority Group, in order to investigate haplotype frequencies of Salar population, evaluate their usefulness in forensic applications, and enrich Chinese population genetic informational resources. Out of a total of 133 individuals 123 showed different haplotypes, while six haplotypes occurred more than once. The overall haplotype diversity for the Y-STRs loci was 0.9983, and the discrimination capacity was 0.9248.

  • population genetics for y chromosomal strs haplotypes of chinese tibetan Ethnic Minority Group in tibet
    Forensic Science International, 2006
    Co-Authors: Bofeng Zhu, Jun Zhu, Shunzhi Liu, Jingfeng Huang, Youcai Wang, Liping Chen, Qianzi Zhao, Yao Liu
    Abstract:

    Y-chromosomal STRs loci were analyzed from a sample of 119 healthy unrelated autochthonous male individuals of Chinese Tibetan Ethnic Minority Group using a multiplex PCR system. Allele and haplotype frequencies for DYS19, DYS389 I, DYS389 II, DYS390, DYS391, DYS392, DYS393, DYS385a,b, DYS438, and DYS439 were determined by the Y-PLEXtrade mark 12 kit. The gene diversity values for the Y-STRs loci ranged from 0.3347 (DYS438) to 0.9547 (DYS385a,b). A total of 110 haplotypes were identified in the Y-STR loci, among which 104 were unique, while six occurred more than once. The overall haplotype diversity for the Y-STRs loci was 0.9981, and the discrimination capacity was 0.9897. The results in the present study can be used for routine forensic application in the region, and enrich Chinese Ethnical genetic informational resources.

  • genetic polymorphisms for 11 y strs haplotypes of chinese yi Ethnic Minority Group
    Forensic Science International, 2006
    Co-Authors: Bofeng Zhu, Chunmei Shen, Jun Zhu, Qianzi Zhao, Guangli Qian, Ruiyi Shi, Yonghui Dang, Ping Huang, Yao Liu
    Abstract:

    Eleven Y-STRs loci including minimal haplotypes (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, and DYS385a,b) and two additional loci, namely DYS438 and DYS439 have been co-amplified in 100 healthy unrelated males of Chinese Yi Minority Ethnic Group using the Y-PLEX™ 5 and Y-PLEX™ 6 kit, in order to investigate allele and haplotype frequencies of Yi population, evaluate their usefulness in forensic paternity testing and human identification, and enrich Chinese population genetic informational resources. Out of a total of 100 individuals 85 showed different haplotypes, while 8 haplotypes occurred more than once. The overall haplotype diversity for 11 Y-STRs loci was 0.9945.

  • population genetics for y strs haplotypes of chinese ewenki Ethnic Minority Group
    Journal of Forensic Sciences, 2005
    Co-Authors: Bofeng Zhu, Chunmei Shen, Jun Zhu, Zhaozhong Gong, Gong Yang, Jie Zhao, Yao Liu
    Abstract:

    Chinese Ewenki Ethnic Minority Group, with a population of 26,300 in a statistical survey conducted in 2000, has a lifestyle of nomad, and is distributed across seven counties in the Inner Mongolia Autonomous Region and in Nahe County of Heilongjiang Province of China. The Ewenki people have no written script but a spoken language with three dialects belonging to the Manchu-Tungusic Group of the Altai language family. Raising reindeers is the key livelihood of Ewenkis.