The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform
Jan H Van Maarseveen - One of the best experts on this subject based on the ideXlab platform.
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stereoselective c terminal peptide elongation from chan lam Evans Reaction generated isopropenyl esters
Organic and Biomolecular Chemistry, 2019Co-Authors: Luuk Steemers, Jan H Van MaarseveenAbstract:C-Terminal dipeptide isopropenyl esters were synthesised by a Cu(II)-mediated Chan–Lam–Evans enol esterification of peptide carboxylic acids and isoprenyl boroxine. These shelf stable peptide esters could be coupled stereoselectively with a variety of amino acid and dipeptide nucleophiles in high yield and purity in the presence of pyrazole/DBU as the catalyst.
Luuk Steemers - One of the best experts on this subject based on the ideXlab platform.
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stereoselective c terminal peptide elongation from chan lam Evans Reaction generated isopropenyl esters
Organic and Biomolecular Chemistry, 2019Co-Authors: Luuk Steemers, Jan H Van MaarseveenAbstract:C-Terminal dipeptide isopropenyl esters were synthesised by a Cu(II)-mediated Chan–Lam–Evans enol esterification of peptide carboxylic acids and isoprenyl boroxine. These shelf stable peptide esters could be coupled stereoselectively with a variety of amino acid and dipeptide nucleophiles in high yield and purity in the presence of pyrazole/DBU as the catalyst.
Sung Ho Kang - One of the best experts on this subject based on the ideXlab platform.
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Stereocontrolled Synthesis of the C1-C10 Fragments of Monensin B and Laidlomycin
Asian Journal of Organic Chemistry, 2015Co-Authors: Sungkyoung Kang, Byunghyuck Jung, Sung Ho KangAbstract:An efficient synthetic route to the C1-C10 fragments of laidlomycin and monensin B has been developed toward their total synthesis. The asymmetric carbons have been elaborated by a syn-aldol Reaction using the oxazolidinone chiral auxiliary for C6 and C7, an anti-aldol Reaction for C3 and C4, the Tishchenko–Evans Reaction for C5, and a chiral building block for C2.
Sungkyoung Kang - One of the best experts on this subject based on the ideXlab platform.
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Stereocontrolled Synthesis of the C1-C10 Fragments of Monensin B and Laidlomycin
Asian Journal of Organic Chemistry, 2015Co-Authors: Sungkyoung Kang, Byunghyuck Jung, Sung Ho KangAbstract:An efficient synthetic route to the C1-C10 fragments of laidlomycin and monensin B has been developed toward their total synthesis. The asymmetric carbons have been elaborated by a syn-aldol Reaction using the oxazolidinone chiral auxiliary for C6 and C7, an anti-aldol Reaction for C3 and C4, the Tishchenko–Evans Reaction for C5, and a chiral building block for C2.
Byunghyuck Jung - One of the best experts on this subject based on the ideXlab platform.
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Stereocontrolled Synthesis of the C1-C10 Fragments of Monensin B and Laidlomycin
Asian Journal of Organic Chemistry, 2015Co-Authors: Sungkyoung Kang, Byunghyuck Jung, Sung Ho KangAbstract:An efficient synthetic route to the C1-C10 fragments of laidlomycin and monensin B has been developed toward their total synthesis. The asymmetric carbons have been elaborated by a syn-aldol Reaction using the oxazolidinone chiral auxiliary for C6 and C7, an anti-aldol Reaction for C3 and C4, the Tishchenko–Evans Reaction for C5, and a chiral building block for C2.