The Experts below are selected from a list of 234 Experts worldwide ranked by ideXlab platform
James D Cherry - One of the best experts on this subject based on the ideXlab platform.
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Exchange Blood Transfusion in the management of severe pertussis in young infants
Pediatric Infectious Disease Journal, 2013Co-Authors: Delma Nieves, John S Bradley, Jessie Gargas, Wilbert H Mason, Deborah Lehman, Samuel M Lehman, Erin L Murray, Kathleen Harriman, James D CherryAbstract:: We analyzed data from 10 young infants who received Exchange Blood Transfusions for management of severe pertussis. Our data are insufficient to address efficacy of the procedure, but our data, as well as previous reports in the literature, indicate that if the procedure is to be successful, it should be done before organ failure has occurred and immediately if shock/hypotension occur.
Rajesh M Prabhu - One of the best experts on this subject based on the ideXlab platform.
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Clinical review: Severe malaria
Critical Care, 2003Co-Authors: Andrej Trampuz, Matjaz Jereb, Igor Muzlovic, Rajesh M PrabhuAbstract:Malaria represents a medical emergency because it may rapidly progress to complications and death without prompt and appropriate treatment. Severe malaria is almost exclusively caused by Plasmodium falciparum . The incidence of imported malaria is increasing and the case fatality rate remains high despite progress in intensive care and antimalarial treatment. Clinical deterioration usually appears 3–7 days after onset of fever. Complications involve the nervous, respiratory, renal, and/or hematopoietic systems. Metabolic acidosis and hypoglycemia are common systemic complications. Intravenous quinine and quinidine are the most widely used drugs in the initial treatment of severe falciparum malaria, whereas artemisinin derivatives are currently recommended for quinine-resistant cases. As soon as the patient is clinically stable and able to swallow, oral treatment should be given. The intravascular volume should be maintained at the lowest level sufficient for adequate systemic perfusion to prevent development of acute respiratory distress syndrome. Renal replacement therapy should be initiated early. Exchange Blood Transfusion has been suggested for the treatment of patients with severe malaria and high parasitemia. For early diagnosis, it is paramount to consider malaria in every febrile patient with a history of travel in an area endemic for malaria.
Rainer Weber - One of the best experts on this subject based on the ideXlab platform.
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Exchange Blood Transfusion in severe falciparum malaria retrospective evaluation of 61 patients treated with compared to 63 patients treated without Exchange Transfusion
Tropical Medicine & International Health, 1997Co-Authors: G D Burchard, J Kroger, Jurgen Knobloch, W J Hartmann, D Eichenlaub, O Moling, K Fleischer, J Van Den Ende, H E Demey, Rainer WeberAbstract:Summary The rationale for Exchange Blood Transfusion (ET) in severe falciparum malaria is threefold: reduction of parasitaemia, reduction of presumptive 'toxic' factors, and improvement of the rheological quality of the Blood. We evaluated the records of 61 patients treated with ET to describe the present status of malaria treatment in Germany, Austria and Switzerland and to assess the efficacy of ET. Clinical data of 61 patients treated with ET were compared to data of 63 patients treated in 2 hospitals where ETs were generally not performed. We found that Exchange Transfusion is applied according to the clinician's subjective impression rather than strict guidelines. Logistic regression analysis adjusting for the differences in clinical parameters between patients treated with or without ET did not identify treatment as a prognostic indicator (odds ratio for relative risk of death with ET: 1.3; 95% CI: 0.4-4.9). Exchange Transfusion did not significantly improve the unfavourable prognosis in cases of severe falciparum malaria. However, failure to reach statistical significance may be due to the retrospective design of the study and therefore non-systematic approach.
J Lankoande - One of the best experts on this subject based on the ideXlab platform.
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preventive Exchange Blood Transfusion in pregnant women with sickle cell disease maternal and perinatal prognosis in a country with limited resources burkina faso
Open Journal of Obstetrics and Gynecology, 2016Co-Authors: Hyacinthe Zamane, Dantola Paul Kain, Sibraogo Kiemtore, Abdoul Azize Diallo, Jean Baptiste Valea, Samba Diallo, Fabienne Sanou, J LankoandeAbstract:Context: In pregnant women with sickle cell disease, the management with Exchange Transfusion could be useful in improving the prognosis of mother and child by reducing the level of hemoglobin S less than 40%. Objective: To analyze the maternal and perinatal outcome during the program of the Exchange Transfusion in pregnant women with sickle cell disease. Patients and Methods: We conducted a prospective study over a period of 18 months. Pregnant women with a major form of sickle cell disease were included. A manual Blood Exchange Transfusion was performed monthly. We monitored the occurrence of maternal and perinatal morbidity during the follow-up. Results: A total of 42 pregnant women with sickle cell disease were monitored. The frequency of infectious episodes and vaso-occlusive crisis was significantly reduced, respectively from 47.6% and 83.3% before the beginning of the Blood Exchanges Transfusion to 11.9% and 16.7% during Blood Exchanges Transfusion program. All newborns were alive at birth with an Apgar score higher or equal to 7 at the 5th minute. The rate of admission of the newborns at neonatal intensive care unit was 9.3%. Maternal mortality was estimated at 7.1% and there was no early neonatal mortality. Conclusion: Prophylactic Exchange Transfusion reduces infections and the reoccurrence of vaso-occlusive crisis, which has an impact on perinatal prognosis.
Delma Nieves - One of the best experts on this subject based on the ideXlab platform.
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Exchange Blood Transfusion in the management of severe pertussis in young infants
Pediatric Infectious Disease Journal, 2013Co-Authors: Delma Nieves, John S Bradley, Jessie Gargas, Wilbert H Mason, Deborah Lehman, Samuel M Lehman, Erin L Murray, Kathleen Harriman, James D CherryAbstract:: We analyzed data from 10 young infants who received Exchange Blood Transfusions for management of severe pertussis. Our data are insufficient to address efficacy of the procedure, but our data, as well as previous reports in the literature, indicate that if the procedure is to be successful, it should be done before organ failure has occurred and immediately if shock/hypotension occur.
