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Hideaki Kado - One of the best experts on this subject based on the ideXlab platform.
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modification of Expanded Polytetrafluoroethylene valved conduit using the thin type leaflets
The Journal of Thoracic and Cardiovascular Surgery, 2018Co-Authors: Yusuke Yamamoto, Takako Miyazaki, Masaaki Yamagishi, Hitoshi Yaku, Satoshi Asada, Yoshinobu Maeda, Hideaki KadoAbstract:Abstract Objectives The Expanded Polytetrafluoroethylene conduit with fan-shaped leaflets and bulging sinuses for right ventricular outflow tract reconstruction was modified with a newly developed thin-type Expanded Polytetrafluoroethylene leaflet. The purpose of this study was to evaluate the clinical outcomes and hemodynamic performance of the modified conduit. Methods From January 2010 to December 2013, 149 patients underwent definitive right ventricular outflow tract reconstruction using the Expanded Polytetrafluoroethylene conduit; the 55 patients receiving a conventional conduit (group N) were compared with the 94 patients receiving a modified conduit (group T). Results There were no conduit-related deaths, operative deaths, or reimplantations for conduit failure. The overall survival and freedom from reintervention for conduit-related reasons at 3 years were 98.2% versus 95.6% ( P = .438) and 94.7% versus 97.9% ( P = .954) for groups N and T, respectively. The mean peak pressure gradients were 22.6 ± 15.6 mm Hg versus 18.2 ± 11.5 mm Hg ( P = .161), and in the subanalysis within small-sized conduits, they were 30.2 ± 16.5 mm Hg versus 20.4 ± 10.7 mm Hg ( P = .034). Regarding conduit insufficiency, the modified conduit showed a significantly worse grade of insufficiency ( P = .014) only in the subanalysis within large-sized conduits. Conclusions Although the clinical outcomes did not differ within midterm observation, the thin-type Expanded Polytetrafluoroethylene leaflet was considered to be suitable for the small-sized conduits, but not for large-sized conduits, based on the comparison of the hemodynamic performance. Long-term follow-up is necessary to address the appropriate sheet type for middle-sized conduits and to estimate the durability of the thin-type leaflet.
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Expanded Polytetrafluoroethylene valved conduit and patch with bulging sinuses in right ventricular outflow tract reconstruction
The Journal of Thoracic and Cardiovascular Surgery, 2007Co-Authors: Takako Miyazaki, Masaaki Yamagishi, Toshihide Nakano, Atsuhiro Nakashima, Kouji Fukae, Hitoshi Yaku, Hideaki KadoAbstract:Objectives No specific prosthetic material is currently recognized as being the most suitable for right ventricular outflow tract reconstruction for congenital heart defects. Prosthetic valves are subject to wear and stress because they do not create vortex flow, which helps natural valves to close. We designed a fan-shaped Expanded Polytetrafluoroethylene valved conduit and patch with bulging sinuses that create vortex flow, making them more reliable over the long term. Methods Bulging sinuses were formed on a sheet of Expanded Polytetrafluoroethylene using a specially designed mold. Fan-shaped Expanded Polytetrafluoroethylene sheets (0.1 mm thick) were anastomosed to the edge of the bulging sinuses as valve leaflets, creating monocuspid, bicuspid, or tricuspid valves. These valves were implanted in 157 patients undergoing right ventricular outflow tract reconstruction (age 16 days to 45.4 years, median 2.0 years), in 48 patients as a conduit, and in 109 patients as a patch. Valve function was followed up by echocardiography for 5.6 to 63.7 months (mean 20.8 months). Results There was no mortality or morbidity, and no patients required reoperation during follow-up. No patients had stenosis, and regurgitation was less than mild in all patients with conduits and moderate in 15 patients (13.8%) with patches, but moderate regurgitation did not further develop during follow-up. Valve motion was fully maintained in all patients. Conclusions The Expanded Polytetrafluoroethylene valved conduits and patches with bulging sinuses showed excellent early-to-midterm results. The valved conduits and patches seem to be promising alternatives to homografts in right ventricular outflow tract reconstruction. Their function will be followed up further.
Masaaki Yamagishi - One of the best experts on this subject based on the ideXlab platform.
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Right ventricle to pulmonary artery conduit with tricuspid Expanded Polytetrafluoroethylene valves.
The Annals of Thoracic Surgery, 2020Co-Authors: Kei Kobayashi, Masaaki Yamagishi, Takeshi Shinkawa, Satoshi Saito, Yuki Nakayama, Ryogo Houki, Hisashi Yoshida, Hiroshi NiinamiAbstract:Abstract Background Excellent outcomes of right ventricle to pulmonary artery conduits with Expanded Polytetrafluoroethylene valves have been reported. The purpose of this study was to evaluate the outcomes of the different material conduits with tricuspid Expanded Polytetrafluoroethylene valves. Methods Forty-one consecutive patients who received right ventricle to pulmonary artery conduit with tricuspid Expanded Polytetrafluoroethylene valves for biventricular repair between April 2004 and December 2016 were studied. The conduits made of autologous pericardial roll or xenograft roll were used in 22 patients (group P) and the conduits made of Expanded Polytetrafluoroethylene tube were used in 19 patients (group G). The conduit reoperation and the conduit dysfunction were analyzed. Results During the median follow-up of 5.8 years, no death related to the conduit was observed. There were 4 reoperations (3 in group P and 1 in group G). Freedom from conduit reoperation at 5 years was 100% in both groups (p=0.30). Freedom from more than moderate conduit stenosis at 5 years after operation was not significantly different between both groups (46.9% in group P vs. 76.3% in group G; p=0.23) despite the group G conduits were significantly smaller, and freedom from more than moderate conduit regurgitation at 5 years was significantly better in group G (63.3% in group P vs. 94.1% in group G; p=0.04). Conclusions The conduit with Expanded Polytetrafluoroethylene valves in the Expanded Polytetrafluoroethylene tubes had better conduit function compared to the conduit with autologous pericardial or xenograft roll, especially in terms of conduit regurgitation.
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modification of Expanded Polytetrafluoroethylene valved conduit using the thin type leaflets
The Journal of Thoracic and Cardiovascular Surgery, 2018Co-Authors: Yusuke Yamamoto, Takako Miyazaki, Masaaki Yamagishi, Hitoshi Yaku, Satoshi Asada, Yoshinobu Maeda, Hideaki KadoAbstract:Abstract Objectives The Expanded Polytetrafluoroethylene conduit with fan-shaped leaflets and bulging sinuses for right ventricular outflow tract reconstruction was modified with a newly developed thin-type Expanded Polytetrafluoroethylene leaflet. The purpose of this study was to evaluate the clinical outcomes and hemodynamic performance of the modified conduit. Methods From January 2010 to December 2013, 149 patients underwent definitive right ventricular outflow tract reconstruction using the Expanded Polytetrafluoroethylene conduit; the 55 patients receiving a conventional conduit (group N) were compared with the 94 patients receiving a modified conduit (group T). Results There were no conduit-related deaths, operative deaths, or reimplantations for conduit failure. The overall survival and freedom from reintervention for conduit-related reasons at 3 years were 98.2% versus 95.6% ( P = .438) and 94.7% versus 97.9% ( P = .954) for groups N and T, respectively. The mean peak pressure gradients were 22.6 ± 15.6 mm Hg versus 18.2 ± 11.5 mm Hg ( P = .161), and in the subanalysis within small-sized conduits, they were 30.2 ± 16.5 mm Hg versus 20.4 ± 10.7 mm Hg ( P = .034). Regarding conduit insufficiency, the modified conduit showed a significantly worse grade of insufficiency ( P = .014) only in the subanalysis within large-sized conduits. Conclusions Although the clinical outcomes did not differ within midterm observation, the thin-type Expanded Polytetrafluoroethylene leaflet was considered to be suitable for the small-sized conduits, but not for large-sized conduits, based on the comparison of the hemodynamic performance. Long-term follow-up is necessary to address the appropriate sheet type for middle-sized conduits and to estimate the durability of the thin-type leaflet.
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Expanded Polytetrafluoroethylene-valved conduit with bulging sinuses for right ventricular outflow tract reconstruction in adults.
The Japanese Journal of Thoracic and Cardiovascular Surgery, 2010Co-Authors: Yosuke Takahashi, Takako Miyazaki, Yasushi Tsutsumi, Osamu Monta, Yasuyuki Kato, Keitaro Kohshi, Tomohiko Sakamoto, Hirokazu Ohashi, Masaaki YamagishiAbstract:Purpose Generally, right ventricular outflow tract reconstruction in adults is performed using homografts or xenograft. However, sufficient graft material is difficult to obtain and has the problems of calcification and structure destruction. We, therefore, evaluated using Expanded Polytetrafluoroethylene- (ePTFE)-valved conduits with bulging sinuses for right ventricular outflow tract reconstruction in adults.
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Expanded Polytetrafluoroethylene valved conduit and patch with bulging sinuses in right ventricular outflow tract reconstruction
The Journal of Thoracic and Cardiovascular Surgery, 2007Co-Authors: Takako Miyazaki, Masaaki Yamagishi, Toshihide Nakano, Atsuhiro Nakashima, Kouji Fukae, Hitoshi Yaku, Hideaki KadoAbstract:Objectives No specific prosthetic material is currently recognized as being the most suitable for right ventricular outflow tract reconstruction for congenital heart defects. Prosthetic valves are subject to wear and stress because they do not create vortex flow, which helps natural valves to close. We designed a fan-shaped Expanded Polytetrafluoroethylene valved conduit and patch with bulging sinuses that create vortex flow, making them more reliable over the long term. Methods Bulging sinuses were formed on a sheet of Expanded Polytetrafluoroethylene using a specially designed mold. Fan-shaped Expanded Polytetrafluoroethylene sheets (0.1 mm thick) were anastomosed to the edge of the bulging sinuses as valve leaflets, creating monocuspid, bicuspid, or tricuspid valves. These valves were implanted in 157 patients undergoing right ventricular outflow tract reconstruction (age 16 days to 45.4 years, median 2.0 years), in 48 patients as a conduit, and in 109 patients as a patch. Valve function was followed up by echocardiography for 5.6 to 63.7 months (mean 20.8 months). Results There was no mortality or morbidity, and no patients required reoperation during follow-up. No patients had stenosis, and regurgitation was less than mild in all patients with conduits and moderate in 15 patients (13.8%) with patches, but moderate regurgitation did not further develop during follow-up. Valve motion was fully maintained in all patients. Conclusions The Expanded Polytetrafluoroethylene valved conduits and patches with bulging sinuses showed excellent early-to-midterm results. The valved conduits and patches seem to be promising alternatives to homografts in right ventricular outflow tract reconstruction. Their function will be followed up further.
Takako Miyazaki - One of the best experts on this subject based on the ideXlab platform.
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modification of Expanded Polytetrafluoroethylene valved conduit using the thin type leaflets
The Journal of Thoracic and Cardiovascular Surgery, 2018Co-Authors: Yusuke Yamamoto, Takako Miyazaki, Masaaki Yamagishi, Hitoshi Yaku, Satoshi Asada, Yoshinobu Maeda, Hideaki KadoAbstract:Abstract Objectives The Expanded Polytetrafluoroethylene conduit with fan-shaped leaflets and bulging sinuses for right ventricular outflow tract reconstruction was modified with a newly developed thin-type Expanded Polytetrafluoroethylene leaflet. The purpose of this study was to evaluate the clinical outcomes and hemodynamic performance of the modified conduit. Methods From January 2010 to December 2013, 149 patients underwent definitive right ventricular outflow tract reconstruction using the Expanded Polytetrafluoroethylene conduit; the 55 patients receiving a conventional conduit (group N) were compared with the 94 patients receiving a modified conduit (group T). Results There were no conduit-related deaths, operative deaths, or reimplantations for conduit failure. The overall survival and freedom from reintervention for conduit-related reasons at 3 years were 98.2% versus 95.6% ( P = .438) and 94.7% versus 97.9% ( P = .954) for groups N and T, respectively. The mean peak pressure gradients were 22.6 ± 15.6 mm Hg versus 18.2 ± 11.5 mm Hg ( P = .161), and in the subanalysis within small-sized conduits, they were 30.2 ± 16.5 mm Hg versus 20.4 ± 10.7 mm Hg ( P = .034). Regarding conduit insufficiency, the modified conduit showed a significantly worse grade of insufficiency ( P = .014) only in the subanalysis within large-sized conduits. Conclusions Although the clinical outcomes did not differ within midterm observation, the thin-type Expanded Polytetrafluoroethylene leaflet was considered to be suitable for the small-sized conduits, but not for large-sized conduits, based on the comparison of the hemodynamic performance. Long-term follow-up is necessary to address the appropriate sheet type for middle-sized conduits and to estimate the durability of the thin-type leaflet.
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Expanded Polytetrafluoroethylene-valved conduit with bulging sinuses for right ventricular outflow tract reconstruction in adults.
The Japanese Journal of Thoracic and Cardiovascular Surgery, 2010Co-Authors: Yosuke Takahashi, Takako Miyazaki, Yasushi Tsutsumi, Osamu Monta, Yasuyuki Kato, Keitaro Kohshi, Tomohiko Sakamoto, Hirokazu Ohashi, Masaaki YamagishiAbstract:Purpose Generally, right ventricular outflow tract reconstruction in adults is performed using homografts or xenograft. However, sufficient graft material is difficult to obtain and has the problems of calcification and structure destruction. We, therefore, evaluated using Expanded Polytetrafluoroethylene- (ePTFE)-valved conduits with bulging sinuses for right ventricular outflow tract reconstruction in adults.
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Expanded Polytetrafluoroethylene valved conduit and patch with bulging sinuses in right ventricular outflow tract reconstruction
The Journal of Thoracic and Cardiovascular Surgery, 2007Co-Authors: Takako Miyazaki, Masaaki Yamagishi, Toshihide Nakano, Atsuhiro Nakashima, Kouji Fukae, Hitoshi Yaku, Hideaki KadoAbstract:Objectives No specific prosthetic material is currently recognized as being the most suitable for right ventricular outflow tract reconstruction for congenital heart defects. Prosthetic valves are subject to wear and stress because they do not create vortex flow, which helps natural valves to close. We designed a fan-shaped Expanded Polytetrafluoroethylene valved conduit and patch with bulging sinuses that create vortex flow, making them more reliable over the long term. Methods Bulging sinuses were formed on a sheet of Expanded Polytetrafluoroethylene using a specially designed mold. Fan-shaped Expanded Polytetrafluoroethylene sheets (0.1 mm thick) were anastomosed to the edge of the bulging sinuses as valve leaflets, creating monocuspid, bicuspid, or tricuspid valves. These valves were implanted in 157 patients undergoing right ventricular outflow tract reconstruction (age 16 days to 45.4 years, median 2.0 years), in 48 patients as a conduit, and in 109 patients as a patch. Valve function was followed up by echocardiography for 5.6 to 63.7 months (mean 20.8 months). Results There was no mortality or morbidity, and no patients required reoperation during follow-up. No patients had stenosis, and regurgitation was less than mild in all patients with conduits and moderate in 15 patients (13.8%) with patches, but moderate regurgitation did not further develop during follow-up. Valve motion was fully maintained in all patients. Conclusions The Expanded Polytetrafluoroethylene valved conduits and patches with bulging sinuses showed excellent early-to-midterm results. The valved conduits and patches seem to be promising alternatives to homografts in right ventricular outflow tract reconstruction. Their function will be followed up further.
Ji Ae Park - One of the best experts on this subject based on the ideXlab platform.
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a new simplified technique for making tricuspid Expanded Polytetrafluoroethylene valved conduit for right ventricular outflow reconstruction
The Annals of Thoracic Surgery, 2013Co-Authors: Si Chan Sung, Yun-hee Chang, Ji Ae ParkAbstract:Several methods of making Expanded Polytetrafluoroethylene valved conduit have been reported, but these techniques are complicated and less reproducible. We have developed a new simplified technique for making a tricuspid Expanded Polytetrafluoroethylene valved conduit for right ventricular outflow tract reconstruction and have been using this conduit for approximately 3 years with excellent results. Our technique is straightforward and reproducible, and the cusps in the conduit are durable due to the use of a specialized suturing technique.
Si Chan Sung - One of the best experts on this subject based on the ideXlab platform.
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a new simplified technique for making tricuspid Expanded Polytetrafluoroethylene valved conduit for right ventricular outflow reconstruction
The Annals of Thoracic Surgery, 2013Co-Authors: Si Chan Sung, Yun-hee Chang, Ji Ae ParkAbstract:Several methods of making Expanded Polytetrafluoroethylene valved conduit have been reported, but these techniques are complicated and less reproducible. We have developed a new simplified technique for making a tricuspid Expanded Polytetrafluoroethylene valved conduit for right ventricular outflow tract reconstruction and have been using this conduit for approximately 3 years with excellent results. Our technique is straightforward and reproducible, and the cusps in the conduit are durable due to the use of a specialized suturing technique.